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Author : Abdelhamid Mahmoud Hasan
Publisher :
ISBN 13 :
Total Pages : 228 pages
Book Rating : 4.:/5 (124 download)
Download or read book Dynamics of Steroid Secretions in Rats written by Abdelhamid Mahmoud Hasan and published by . This book was released on 1985 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gregory Pincus
Publisher : Academic Press
ISBN 13 : 1483270858
Total Pages : 596 pages
Book Rating : 4.4/5 (832 download)
Download or read book Steroid Dynamics written by Gregory Pincus and published by Academic Press. This book was released on 2013-10-22 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Steroid Dynamics compiles papers presented at the Symposium on the Dynamics of Steroid Hormones held in Tokyo, in May 1965. This compilation discusses the effect of LH and ACTH on production and excretion of testosterone in vivo, estrogen receptors in target tissues, and influence of morphine on corticoid production. The binding of steroids to follicular fluid proteins, conjugation and excretion of aldosterone, and active cholesterol pool for corticodogenesis in the rat adrenal are also elaborated. This book likewise covers the dynamics of steroid hormone distribution in the body, biosynthesis of steroids in testicular tissue in vitro, and isotopic dilution methods for the estimation of rates of secretion of the steroid hormones. This publication is a good reference for endocrinologists, biochemists, and medical practitioners interested in steroid dynamics.
Author : Nicole Gallo-Payet
Publisher : Frontiers Media SA
ISBN 13 : 2889452328
Total Pages : 421 pages
Book Rating : 4.8/5 (894 download)
Download or read book ACTH Action in the Adrenal Cortex: From Molecular Biology to Pathophysiology written by Nicole Gallo-Payet and published by Frontiers Media SA. This book was released on 2017-07-27 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: By stimulating adrenal gland and corticosteroid synthesis, the adrenocorticotropic hormone (ACTH) plays a central role in response to stress. In this Research Topic, a particular attention has been given to the recent developments on adrenocortical zonation; the growth-promoting activities of ACTH; the various steps involved in acute and chronic regulation of steroid secretion by ACTH, including the effect of ACTH on circadian rhythms of glucocorticoid secretion. The Research Topic also reviews progress and challenges surrounding the properties of ACTH binding to the MC2 receptor (MC2R), including the importance of melanocortin-2 receptor accessory protein (MRAP) in MC2R expression and function, the various intracellular signaling cascades, which involve not only protein kinase A, the key mediator of ACTH action, but also phosphatases, phosphodiesterases, ion channels and the cytoskeleton. The importance of the proteins involved in the cell detoxification is also considered, in particular the effect that ACTH has on protection against reactive oxygen species generated during steroidogenesis. The impact of the cellular microenvironment, including local production of ACTH is discussed, both as an important factor in the maintenance of homeostasis, but also in pathological situations, such as severe inflammation. Finally, the Research Topic reviews the role that the pituitary-adrenal axis may have in the development of metabolic disorders. In addition to mutations or alterations of expression of genes encoding components of the steroidogenesis and signaling pathways, chronic stress and sleep disturbance are both associated with hyperactivity of the adrenal gland. A resulting effect is increased glucocorticoid secretion inducing food intake and weight gain, which, in turn, leads to insulin and leptin resistance. These aspects are described in detail in this Research Topic by key investigators in the field. Many of the aspects addressed in this Research Topic still represent a stimulus for future studies, their outcome aimed at providing evidence of the central position occupied by the adrenal cortex in many metabolic functions when its homeostasis is disrupted. An in-depth investigation of the mechanisms underlying these pathways will be invaluable in developing new therapeutic tools and strategies.
Author : Paolo Sassone-Corsi
Publisher : Springer
ISBN 13 : 3319270699
Total Pages : 141 pages
Book Rating : 4.3/5 (192 download)
Download or read book A Time for Metabolism and Hormones written by Paolo Sassone-Corsi and published by Springer. This book was released on 2016-04-04 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.
Author :
Publisher :
ISBN 13 :
Total Pages : 776 pages
Book Rating : 4.3/5 (91 download)
Download or read book Research Awards Index written by and published by . This book was released on 1989 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Institutes of Health (U.S.). Division of Research Grants
Publisher :
ISBN 13 :
Total Pages : 1224 pages
Book Rating : 4.3/5 (91 download)
Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1975 with total page 1224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 764 pages
Book Rating : 4.3/5 (91 download)
Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1989 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Robert J. Handa
Publisher : CRC Press
ISBN 13 : 1420041193
Total Pages : 427 pages
Book Rating : 4.4/5 (2 download)
Download or read book Neuroplasticity, Development, and Steroid Hormone Action written by Robert J. Handa and published by CRC Press. This book was released on 2001-07-30 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: A compilation of cutting-edge research, Neuroplasticity, Development, and Steroid Hormone Action explores the effects of steroid hormones on brain development, function, and aging. The experimental approaches used by the authors ranges from molecular to behavioral and endocrine to neurobiological. It contains scientific photographs, line drawings, tables, color illustrations, and graphs, this interesting and timely text covers the neuroplastic effects of steroid hormones throughout the lifetime of various animal models, such as bees, fish, lizards, turtles, birds, mice, rats, and primates.
Author : National Heart, Lung, and Blood Institute
Publisher :
ISBN 13 :
Total Pages : 486 pages
Book Rating : 4.M/5 ( download)
Download or read book Subject Index of Current Research Grants and Contracts Administered by the National Heart, Lung and Blood Institute written by National Heart, Lung, and Blood Institute and published by . This book was released on 1975 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Albert Altchek
Publisher : Elsevier
ISBN 13 : 008049451X
Total Pages : 595 pages
Book Rating : 4.0/5 (84 download)
Download or read book Diagnosis and Management of Ovarian Disorders written by Albert Altchek and published by Elsevier. This book was released on 2003-09-04 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders.KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine
Author :
Publisher :
ISBN 13 :
Total Pages : 610 pages
Book Rating : 4.3/5 ( download)
Download or read book Population Sciences written by and published by . This book was released on with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Heart and Lung Institute
Publisher :
ISBN 13 :
Total Pages : 482 pages
Book Rating : 4.:/5 (319 download)
Download or read book Subject Index of Current Research Grants and Contracts Administered by the National Heart and Lung Institute written by National Heart and Lung Institute and published by . This book was released on 1975 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : W. Savino
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318060143
Total Pages : 190 pages
Book Rating : 4.3/5 (18 download)
Download or read book Endocrine Immunology written by W. Savino and published by Karger Medical and Scientific Publishers. This book was released on 2017-02-28 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decades, several in vitro and in vivo studies have revealed the existence of a very complex network between the neuroendocrine and immune system. Important molecular mechanisms underlying these interactions, in both physiological and pathological conditions, have also been described. Indeed, hormones play a pivotal role in the development and functional regulation of the immune system – both innate and acquired responses. Immune system cells present specific hormone receptors and themselves produce some hormones, thus influencing hormone secretion. More recently, the modulation of hormone secretion has been attempted for treating associated autoimmune disorders, further supporting the strong interplay between the endocrine and immune system. Distinguished experts, who have published extensively in their fields, have contributed comprehensive chapters to this volume. The focus is on the various aspects of endocrine-neuro-immune connections, providing an updated panorama - from basics to clinical applications - of current knowledge and still debated issues.
Author :
Publisher :
ISBN 13 :
Total Pages : 2730 pages
Book Rating : 4.3/5 (91 download)
Download or read book Chemical Abstracts written by and published by . This book was released on 2002 with total page 2730 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309051266
Total Pages : 188 pages
Book Rating : 4.3/5 (9 download)
Download or read book Nutrient Requirements of Laboratory Animals, written by National Research Council and published by National Academies Press. This book was released on 1995-02-01 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.
Author :
Publisher :
ISBN 13 :
Total Pages : 666 pages
Book Rating : 4.:/5 (45 download)
Download or read book Journal of Physiology and Pharmacology written by and published by . This book was released on 1992 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lajos Okolicsanyi
Publisher : Springer Science & Business Media
ISBN 13 : 3642726313
Total Pages : 435 pages
Book Rating : 4.6/5 (427 download)
Download or read book Assessment and Management of Hepatobiliary Disease written by Lajos Okolicsanyi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contributions to this volume cover all aspects of the assessment and management of hepatobiliary disease. The focal points of the book consist of three state-of-the-art summaries. The first of these deals with the highly topical problem of liver transplants from the point of view of patient selection. The second considers drug-induced liver injury in view of the fact that the liver is the main metabolic site for a number of drugs. The final summary deals with liver and aging: it asks whether the liver follows the aging process of the host organisms and whether the liver of aged liver transplant candidate donors could be suitable for grafting. Aside from these topics, the volume presents basic research on hepatic transport mechanisms, intrahepatic cholestasis and gall-stone disease, which serves as a background for the topics more specifically concerning the assessment of liver function. Much of the book is then devoted to the management of the commonest forms of liver diseases and their complications, such as chronic active hepatitis, liver cirrhosis, portal hypertension, hepatic encephalopathy, hepatorenal syndrome, and ascites.
