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Drugs From The Sea
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Book Synopsis Sex, Drugs, and Sea Slime by : Ellen Prager
Download or read book Sex, Drugs, and Sea Slime written by Ellen Prager and published by University of Chicago Press. This book was released on 2011-10 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: When viewed from a quiet beach, the ocean can seem calm, even serene. But hidden beneath the sea's waves are a staggering variety of active creatures, engaged in the never-ending struggles of life--to reproduce, to eat, and to avoid being eaten. Marine scientist Ellen Prager takes us deep into the sea to introduce a cast of fascinating and bizarre creatures. From the tiny arrow worms whose voracious ways may lead to death by overeating, to the lobsters that battle rivals or seduce mates with their urine, Prager reveals the ways they interact as predators, prey, or potential mates. And while these animals make for some jaw-dropping stories--there's far more to Prager's account than entertaining anecdotes: again and again, she illustrates the crucial connections between life in the ocean and humankind, in everything from our food supply to our economy, and in drug discovery, biomedical research, and popular culture.--From publisher description.
Book Synopsis Handbook of Anticancer Drugs from Marine Origin by : Se-Kwon Kim
Download or read book Handbook of Anticancer Drugs from Marine Origin written by Se-Kwon Kim and published by Springer. This book was released on 2014-11-27 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.
Book Synopsis Pharmaceuticals in Marine and Coastal Environments by : Juan Carlos Duran-Alvarez
Download or read book Pharmaceuticals in Marine and Coastal Environments written by Juan Carlos Duran-Alvarez and published by Elsevier. This book was released on 2021-06-23 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceuticals in Marine and Coastal Environments: Occurrence, Effects, and Challenges in a Changing World is divided into three sections that address a) coastal areas as the main entrance of pharmaceuticals into the ocean, b) the occurrence and distribution of pharmaceuticals in the environmental compartments of the ocean media, and c) the effects that such pollutants may cause to the exposed marine organisms. With its comprehensive discussions, the book provides a wide depiction of the current state-of-the-art on these topics in an effort to open new sources of investigation and find suitable solutions. - Includes maps edited by the Water Information Network System of the International Hydrological Program (IHP-WINS) - Provides a compilation of information regarding the occurrence and distribution of pharmaceuticals in the marine environment which will help establish new and more efficient monitoring programs and new research lines - Depicts the most important results of environmental risk assessments that can be used as a first step for further toxicological studies
Author :Nobuhiro Fusetani Publisher :Karger Medical and Scientific Publishers ISBN 13 :3805570988 Total Pages :164 pages Book Rating :4.8/5 (55 download)
Book Synopsis Drugs from the Sea by : Nobuhiro Fusetani
Download or read book Drugs from the Sea written by Nobuhiro Fusetani and published by Karger Medical and Scientific Publishers. This book was released on 2000-01-01 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book consists of three parts: discovery, development and production of drugs from marine organisms. Marine bacteria, fungi, microalgae, sponges and opisthobranch mollusks have attracted much attention as sources of potential drugs, which is described in the first part. A pain-killing drug developed from the venom of a cone shell is a recent highlight of marine natural product research; the interesting story of its discovery is provided. The second part features an anticancer drug with a novel mode of action which was originally isolated from a songe and a potential antiosteoporotic drug of a hexacoral origin. But the most serious problem for development of drugs from the sea remains supply. Two possible solutions, production by fermentation and by aquaculture, are described in the third part. Identification and culture of symbiotic bacteria which are responsible for the production of bioactive sponge metabolites are the main objectives for many researchers.
Book Synopsis Marine Niche: Applications in Pharmaceutical Sciences by : Neelam M Nathani
Download or read book Marine Niche: Applications in Pharmaceutical Sciences written by Neelam M Nathani and published by Springer Nature. This book was released on 2020-11-09 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive study of biological molecules acquired from marine organisms, which have been exploited for drug discovery with the aim to treat human diseases. Biomolecules have potential impacts on a diverse range of fields, including medical and pharmaceutical science, industrial science, biotechnology, basic research, molecular science, environmental science and climate change, etc. To understand and effectively apply medicinally important biomolecules, multidisciplinary approaches are called for. The ocean remains a rich biological resource, and the vast untapped potential of novel molecules from marine bio-resources has caught the interest of more and more researchers. These novel biological compounds have never been found in terrestrial or other ecosystems, but only in this rich niche. Advances in sampling techniques and technologies, along with increased funding for research and nature conservation, have now encouraged scientists to look deeper in the waters. Aquaculture supports both tremendous seafood production and the bulk production of marine-derived drugs. Furthermore, molecular methods are now being extensively employed to explore the untapped marine microbial diversity. With the help of molecular and biotech tools, the ability of marine organisms to produce new biosynthetic drugs can be greatly enhanced. This book provides an extensive compilation of the latest information on marine resources and their undisputedly vital role in the treatment of diverse ailments.
Book Synopsis Marine Compounds and Cancer by : Friedemann Honecker
Download or read book Marine Compounds and Cancer written by Friedemann Honecker and published by MDPI. This book was released on 2018-06-26 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Marine Compounds and Cancer" that was published in Marine Drugs
Download or read book Phylum Bryozoa written by Thomas Schwaha and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-11-23 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: With an account of over 6.000 recent and 15.000 fossil species, phylum Bryozoa represents a quite large and important phylum of colonial filter feeders. This volume of the series Handbook of Zoology contains new findings on phylogeny, morphology and evolution that have significantly improved our knowledge and understanding of this phylum. It is a comprehensive book that will be a standard for many specialists but also newcomers to the field of bryozoology.
Download or read book Drugged written by Richard J. Miller and published by Oxford University Press, USA. This book was released on 2014 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Miller takes readers on an eye-opening tour of psychotropic drugs, describing the various kinds, how they were discovered and developed, and how they have played multiple roles in virtually every culture.
Download or read book Jackpot written by Jason Ryan and published by Rowman & Littlefield. This book was released on 2012-08-07 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1970s and early '80s, a cadre of freewheeling, Southern pot smugglers lived at the crossroads of Miami Vice and a Jimmy Buffett song. These irrepressible adventurers unloaded nearly a billion dollars worth of marijuana and hashish through the eastern seaboard’s marshes. Then came their undoing: Operation Jackpot, one of the largest drug investigations ever and an opening volley in Ronald Reagan’s War on Drugs. In Jackpot, author Jason Ryan takes us back to the heady days before drug smuggling was synonymous with deadly gunplay. During this golden age of marijuana trafficking, the country’s most prominent kingpins were a group of wayward and fun-loving Southern gentlemen who forsook college educations to sail drug-laden luxury sailboats across the Mediterranean, the Atlantic, and the Caribbean. Les Riley, Barry Foy, and their comrades eschewed violence as much as they loved pleasure, and it was greed, lust, and disaster at sea that ultimately caught up with them, along with the law. In a cat-and-mouse game played out in exotic locations across the globe, the smugglers sailed through hurricanes, broke out of jail and survived encounters with armed militants in Colombia, Grenada and Lebanon. Based on years of research and interviews with imprisoned and recently released smugglers and the law enforcement agents who tracked them down, Jackpot is sure to become a classic story from America's controversial Drug Wars. “The adventures, the long-gone economy, and the sting that ultimately brought them down and changed US drug policy are meticulously documented and lucidly spun…. Part New Yorker feature-part Jimmy Buffet song. . . . The result is adventuresome, lavish, informative fun.” —GQ “[A] rollicking story, Ryan manages to pack in one amusing tale after another.... Jackpot is a rip-roaring good read.” —Charleston City Paper “High times on the high seas: Investigative reporter Ryan recounts the glory days of dope smuggling and their terrible denouement.... A well-told tale of true crime that provides a few good arguments for why it should not be a crime at all.” —Kirkus Reviews “Reads like an international thriller. . . . chock-a-block with hilarious and hair-raising anecdotes of fast times.” —New York Journal of Books “[A] thoroughly researched account of Operation Jackpot, the drug investigation that ended the reign of South Carolina’s ‘gentlemen smugglers,’.... Ryan recreates the era with a vivid, sun-drenched intensity.” —Publishers Weekly
Download or read book Marine Medicine written by Eric Weiss and published by The Mountaineers Books. This book was released on 2012-04-19 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: CLICK HERE to download the sections on abdominal injury, dislocations, and animal stings from Marine Medicine * Advice for sailing, pleasure boating, fishing, and diving emergencies * More than 100 illustrations * Near-shore or out-at-sea first aid covered * As vital a piece of gear as your PFD and signal flares This edition features the latest information on marine first aid. It includes chapters on hazardous marine life, submersion injury and dive medicine, rescue and evacuation of the sick and injured, wound cleaning and closing, and much more.
Download or read book Venoms to Drugs written by Glenn F. King and published by Royal Society of Chemistry. This book was released on 2015-01-27 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. This unique book provides an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. Topics covered include chemistry and structural biology of animal venoms, proteomic and transcriptomic approaches to drug discovery, bioassays, high-throughput screens and target identification, and reptile, scorpion, spider and cone snail venoms as a platform for drug development. Case studies are used to illustrate methods and successes and highlight issues surrounding administration and other important lessons that have been learnt from the development of approved therapeutics based on venoms. The first text to focus on this fascinating area and bridging an important gap, this book provides the reader with essential and current knowledge on this fast-developing area. Venoms to Drugs will find wide readership with researchers working in academia and industry working in all medicinal and pharmaceutical areas.
Download or read book Red Crew written by Jim Howe and published by Naval Institute Press. This book was released on 2018-06-15 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Red Crew is a first-hand account of U.S. Coast Guard anti-smuggling operations during the early years of the nation’s maritime war on drugs. Jim Howe describes his experience as the executive officer of a specialized drug-hunting crew that sailed in then-state-of-the-art “surface effect ships,” a small flotilla of high-speed vessels pressed into the drug war on short notice. In the early 1980s, South Florida and the Caribbean were awash in illicit drugs, with hundreds of smuggling organizations bringing huge loads of marijuana, and later cocaine, into the United States. To fight this epidemic, the Reagan administration led a massive effort to disrupt shore-side gangs while bolstering interdiction activity at sea. To increase the number of days at sea for each surface effect ship, a “multi-crewing” concept was employed, with four teams of sixteen sailors—the Red, Blue, Green, and Gold Crews—rotating among three hulls. Through its first-person narrative, Red Crew offers a rare glimpse into the day-to-day pressures, challenges, failures, and successes of Coast Guard cuttermen as they carried out complex and dangerous missions. Red Crew provides a unique historical view of the early days in the Coast Guard’s war on drugs, and is the only book-length history of the diminutive, one-of-a-kind surface effect ship fleet.
Book Synopsis Pharmaceuticals in the aquatic environment of the Baltic Sea region by : Vieno, Niina
Download or read book Pharmaceuticals in the aquatic environment of the Baltic Sea region written by Vieno, Niina and published by UNESCO Publishing. This book was released on 2017-09-25 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Natural Products written by Lixin Zhang and published by Springer Science & Business Media. This book was released on 2007-11-17 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
Book Synopsis Drug-like Properties: Concepts, Structure Design and Methods by : Li Di
Download or read book Drug-like Properties: Concepts, Structure Design and Methods written by Li Di and published by Elsevier. This book was released on 2010-07-26 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties. - Serves as an essential working handbook aimed at scientists and students in medicinal chemistry - Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies - Discusses improvements in pharmacokinetics from a practical chemist's standpoint
Book Synopsis A Brief History of Drugs by : Antonio Escohotado
Download or read book A Brief History of Drugs written by Antonio Escohotado and published by Simon and Schuster. This book was released on 1999-05-01 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: A clear-eyed look at the instrumental role drugs have played in our cultural, social, and spiritual development. • First American publication of the surprising European bestseller. • Examines everything from the ancient use of ergot and datura to the modern phenomenon of "designer" drugs such as Ecstasy and crack cocaine. From remotest antiquity to the present era of designer drugs and interdiction, drugs have played a prominent role in the cultural, spiritual, and social development of civilizations. Antonio Escohotado demonstrates how the history of drugs illuminates the history of humanity as he explores the long relationship between mankind and mind-altering substances. Hemp, for example, has been used in India since time immemorial to stimulate mental agility and sexual prowess. Aristotle's disciple Theophrastus testifies to the use of datura by the ancient Greeks and further evidence links the rites at Eleusis to the ingestion of a hallucinogen. Similar examples can be found in cultures as diverse as the Celts, the ancient Egyptians, the Aztecs, and other indigenous peoples around the world. Professor Escohotado also looks at the present-day differences that exist between the more drug-tolerant societies like Holland and Switzerland and countries advocating complete repression of these substances. The author provides a comprehensive analysis of the enormous social costs of the drug war that is coming under increasing fire from all levels of society. Professor Escohotado's work demonstrates that drugs have always existed and been used by societies throughout the world and the contribution they have made to humanity's development has been enormous. The choice we face today is to teach people how to use them correctly or to continue to indiscriminately demonize them. "Just say no," the author says, is not an option. Just say "know" is. Antonio Escohotado is a professor of philosophy and social science methodology at the National University of Distance Education in Madrid, Spain. He travels widely, offering lectures and seminars on the subject of drugs and history.
Book Synopsis Narcosubmarines by : Javier Guerrero C.
Download or read book Narcosubmarines written by Javier Guerrero C. and published by Springer Nature. This book was released on 2019-09-26 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the encounters of Colombian drug smugglers and the Colombian Navy, both in the open seas and along coastlines. Javier Guerrero C. specifically examines the technologies involved in the War on Drugs, such as the narcosubmarines and patrol boats, the knowledge required to transport drugs and the knowledge required to stop the illicit flows. The author presents compelling new evidence for advancing an understanding of technological innovation in antagonist contexts, as well as the symbiotic and co-evolutionary character of the process of technological innovation in the War on Drugs. This book will appeal both to practitioners and scholars interested in the War on Drugs and the production of technologies in outlaw contexts.
