The Organic Chemistry of Drug Synthesis, Volume 7

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Publisher : John Wiley & Sons
ISBN 13 : 0470180668
Total Pages : 288 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis The Organic Chemistry of Drug Synthesis, Volume 7 by : Daniel Lednicer

Download or read book The Organic Chemistry of Drug Synthesis, Volume 7 written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 2007-12-14 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The classic reference on the synthesis of medicinal agents -- now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6. Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered. As in the previous volumes, materials are organized by chemical class and syntheses originate with available starting materials. Organized to make the information accessible, this resource covers disease state, rationale for method of drug therapy, and the biological activities of each compound and preparation. The Organic Chemistry of Drug Synthesis, Volume 7 is a hands-on reference for medicinal and organic chemists, and a great resource for graduate and advanced undergraduate students in organic and medicinal chemistry.

The Art of Drug Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 0470134968
Total Pages : 294 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis The Art of Drug Synthesis by : Douglas S. Johnson

Download or read book The Art of Drug Synthesis written by Douglas S. Johnson and published by John Wiley & Sons. This book was released on 2007-07-09 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-selling drugs on the market today. An introduction to each drug is provided, as well as background to the biology, pharmacology, pharmacokinetics, and drug metabolism, followed by a detailed account of the drug synthesis. Edited by prominent scientists working in drug discovery for Pfizer Meets the needs of a growing community of researchers in pharmaceutical R&D Provides a useful guide for practicing pharmaceutical scientists as well as a text for medicinal chemistry students An excellent follow-up to the very successful first book by these editors, Contemporary Drug Synthesis, but with all new therapeutic categories and drugs discussed.

Early Drug Development, 2 Volume Set

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Publisher : John Wiley & Sons
ISBN 13 : 3527341498
Total Pages : 810 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Early Drug Development, 2 Volume Set by : Fabrizio Giordanetto

Download or read book Early Drug Development, 2 Volume Set written by Fabrizio Giordanetto and published by John Wiley & Sons. This book was released on 2018-12-10 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt: This one-stop reference systematically covers key aspects in early drug development that are directly relevant to the discovery phase and are required for first-in-human studies. Its broad scope brings together critical knowledge from many disciplines, ranging from process technology to pharmacology to intellectual property issues. After introducing the overall early development workflow, the critical steps of early drug development are described in a sequential and enabling order: the availability of the drug substance and that of the drug product, the prediction of pharmacokinetics and -dynamics, as well as that of drug safety. The final section focuses on intellectual property aspects during early clinical development. The emphasis throughout is on recent case studies to exemplify salient points, resulting in an abundance of practice-oriented information that is usually not available from other sources. Aimed at medicinal chemists in industry as well as academia, this invaluable reference enables readers to understand and navigate the challenges in developing clinical candidate molecules that can be successfully used in phase one clinical trials.

Current Drug Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 1119847257
Total Pages : 404 pages
Book Rating : 4.1/5 (198 download)

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Book Synopsis Current Drug Synthesis by : Jie Jack Li

Download or read book Current Drug Synthesis written by Jie Jack Li and published by John Wiley & Sons. This book was released on 2022-09-21 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Drug Synthesis The latest entry in the widely read Drug Synthesis series In Current Drug Synthesis, accomplished medicinal chemist and researcher Dr. Jie Jack Li and 27 expert coauthors deliver an authoritative and comprehensive discussion of the medicinal chemistry of current drugs, as well as the cutting-edge science involved in their synthesis. The book demystifies the process of modern drug discovery for both industry practitioners and students, while capturing the state-of-the-art techniques used to discover some of the most impactful medicines on the market today. Covering six different disease areas – including infectious disease, cancer, cardiovascular and metabolic disease, the central nervous system, anti-inflammatory disease, and a miscellaneous section – the book explores 18 different drugs before concluding with chapters on computational drug discovery and peptide drugs. Each chapter includes coverage of background material on a relevant drug class or disease indication and key aspects of drug discovery, including structure-activity relationships, pharmacokinetics, drug metabolism, efficacy, and safety. Readers will also find: Thorough introductions to drugs for infectious diseases, including relebactam, vaborbactam, and baloxavir marboxil In-depth treatments of cancer-treating drugs, including darolutamide, venetoclax, and osimertinib Comprehensive explorations of central nervous system drugs, including zuranolone and risdiplam Extensive discussions of computational drug discovery and peptide drugs Perfect for medicinal, organic, synthetic, and process chemists, Current Drug Synthesis will also earn a place in the libraries of research scientists working in lead optimization and process development, as well as graduate students studying organic chemistry, heterocyclic chemistry, or medicinal chemistry.

Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 111953030X
Total Pages : 6057 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set by :

Download or read book Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set written by and published by John Wiley & Sons. This book was released on 2021-04-20 with total page 6057 pages. Available in PDF, EPUB and Kindle. Book excerpt: Burger’s Medicinal Chemistry, Drug Discovery and Development Explore the freshly updated flagship reference for medicinal chemists and pharmaceutical professionals The newly revised eighth edition of the eight-volume Burger’s Medicinal Chemistry, Drug Discovery and Development is the latest installment in this celebrated series covering the entirety of the drug development and discovery process. With the addition of expert editors in each subject area, this eight-volume set adds 35 chapters to the extensive existing chapters. New additions include analyses of opioid addiction treatments, antibody and gene therapy for cancer, blood-brain barrier, HIV treatments, and industrial-academic collaboration structures. Along with the incorporation of practical material on drug hunting, the set features sections on drug discovery, drug development, cardiovascular diseases, metabolic diseases, immunology, cancer, anti-Infectives, and CNS disorders. The text continues the legacy of previous volumes in the series by providing recognized, renowned, authoritative, and comprehensive information in the area of drug discovery and development while adding cutting-edge new material on issues like the use of artificial intelligence in medicinal chemistry. Included: Volume 1: Methods in Drug Discovery, edited by Kent D. Stewart Volume 2: Discovering Lead Molecules, edited by Kent D. Stewart Volume 3: Drug Development, edited by Ramnarayan S. Randad and Michael Myers Volume 4: Cardiovascular, Endocrine, and Metabolic Diseases, edited by Scott D. Edmondson Volume 5: Pulmonary, Bone, Immunology, Vitamins, and Autocoid Therapeutic Agents, edited by Bryan H. Norman Volume 6: Cancer, edited by Barry Gold and Donna M. Huryn Volume 7: Anti-Infectives, edited by Roland E. Dolle Volume 8: CNS Disorders, edited by Richard A. Glennon Perfect for research departments in the pharmaceutical and biotechnology industries, Burger’s Medicinal Chemistry, Drug Discovery and Development can be used by graduate students seeking a one-stop reference for drug development and discovery and deserves its place in the libraries of biomedical research institutes, medical, pharmaceutical, and veterinary schools.

Synthesis of Essential Drugs

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Publisher : Elsevier
ISBN 13 : 008046212X
Total Pages : 635 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Synthesis of Essential Drugs by : Ruben Vardanyan

Download or read book Synthesis of Essential Drugs written by Ruben Vardanyan and published by Elsevier. This book was released on 2006-03-10 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs. This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO's Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry. * Provides a brief description of methods of synthesis, activity and implementation of all drug types* Includes synonyms* Includes over 2300 references

Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1437720609
Total Pages : 4306 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases E-Book by : John E. Bennett

Download or read book Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases E-Book written by John E. Bennett and published by Elsevier Health Sciences. This book was released on 2009-10-19 with total page 4306 pages. Available in PDF, EPUB and Kindle. Book excerpt: After thirty years, PPID is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. Mandell, Bennett, and Dolin have substantially revised and meticulously updated, this new edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 7th Edition helps you identify and treat whatever infectious disease you see. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Get the answers to questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you’ll find in any other infectious disease resource. Find the latest diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on influenza (new pandemic strains); new Middle East respiratory syndrome (MERS) virus; probiotics; antibiotics for resistant bacteria; antifungal drugs; new antivirals for hepatitis B and C; Clostridium difficile treatment; sepsis; advances in HIV prevention and treatment; viral gastroenteritis; Lyme disease; Helicobacter pylori; malaria; infections in immunocompromised hosts; immunization (new vaccines and new recommendations); and microbiome. Benefit from fresh perspectives and global insights from an expanded team of international contributors. Find and grasp the information you need easily and rapidly with newly added chapter summaries. These bulleted templates include diagnosis, therapy, and prevention and are designed as a quick summary of the chapter and to enhance relevancy in search and retrieval on Expert Consult. Stay current on Expert Consult with a thorough and regularly scheduled update program that ensures access to new developments in the field, advances in therapy, and timely information. Access the information you need easily and rapidly with new succinct chapter summaries that include diagnosis, therapy, and prevention. Experience clinical scenarios with vivid clarity through a richly illustrated, full-color format that includes 1500 photographs for enhanced visual guidance.

Strategies for Organic Drug Synthesis and Design

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Publisher : John Wiley & Sons
ISBN 13 : 9780470399590
Total Pages : 700 pages
Book Rating : 4.3/5 (995 download)

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Book Synopsis Strategies for Organic Drug Synthesis and Design by : Daniel Lednicer

Download or read book Strategies for Organic Drug Synthesis and Design written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 2009-03-04 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as medical professionals, by providing a useful guide for designing and synthesizing pharmaceutical agents. Additionally, it is a useful text for medicinal chemistry students.

Handbook of Modern Pharmaceutical Analysis

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Publisher : Academic Press
ISBN 13 : 9780120455553
Total Pages : 566 pages
Book Rating : 4.4/5 (555 download)

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Book Synopsis Handbook of Modern Pharmaceutical Analysis by : Satinder Ahuja

Download or read book Handbook of Modern Pharmaceutical Analysis written by Satinder Ahuja and published by Academic Press. This book was released on 2001 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the role modern pharmaceutical analysis plays in the development of new drugs. Detailed information is provided as to how the quality of drug products is assured from the point of discovery until the patient uses the drug. Coverage includes state-of-the-art topics such as analytics for combinatorial chemistry and high-throughput screening, formulation development, stability studies, international regulatory aspects and documentation, and future technologies that are likely to impact the field. Emphasis is placed on current, easy-to-follow methods that readers can apply in their laboratories. No book has effectively replaced the very popular text, Pharmaceutical Analysis, that was edited in the 1960s by Tak Higuchi. This book will fill that gap with an up-to-date treatment that is both handy and authoritative.

Modern Natural Product Synthesis

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Publisher : Springer Nature
ISBN 13 : 9819716195
Total Pages : 518 pages
Book Rating : 4.8/5 (197 download)

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Book Synopsis Modern Natural Product Synthesis by : Masahisa Nakada

Download or read book Modern Natural Product Synthesis written by Masahisa Nakada and published by Springer Nature. This book was released on with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Pharmaceutical Era

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Publisher :
ISBN 13 :
Total Pages : 688 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis The Pharmaceutical Era by :

Download or read book The Pharmaceutical Era written by and published by . This book was released on 1924 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Pharmaceutical Era

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Publisher :
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis The Pharmaceutical Era by : Charles W. Parsons

Download or read book The Pharmaceutical Era written by Charles W. Parsons and published by . This book was released on 1919 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Click Reactions in Organic Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 3527694188
Total Pages : 360 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Click Reactions in Organic Synthesis by : Srinivasan Chandrasekaran

Download or read book Click Reactions in Organic Synthesis written by Srinivasan Chandrasekaran and published by John Wiley & Sons. This book was released on 2016-06-22 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on click reactions to focus on organic synthesis, this reference work describes the click concept and underlying mechanisms as well as the main applications in various fields. As such, the chapters cover green chemical synthesis, metal-free click reactions, synthesis of pharmaceuticals, peptides, carbohydrates, DNA, macrocycles, dendrimers, polymers, and supramolecular architectures. By filling a gap in the market, this is the ultimate reference for synthetic chemists in academia and industry aiming for a fast and simple design and synthesis of novel compounds with useful properties.

Homologation Reactions

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Publisher : John Wiley & Sons
ISBN 13 : 3527830219
Total Pages : 1256 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Homologation Reactions by : Vittorio Pace

Download or read book Homologation Reactions written by Vittorio Pace and published by John Wiley & Sons. This book was released on 2023-05-24 with total page 1256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a unique summary of homologation strategies in organic synthesis Homologation Reactions presents different concepts underpinning the use of homologating reagents as well as their applications in organic synthesis. It covers in-depth discussions on the rationales governing this kind of transformations with a strong emphasis on mechanistic elements modulating critical aspects (e.g. selectivity) of the processes. In addition, this two-volume work features: Metal carbenoids, ylides, and diazo reagents Homologating agents working under nucleophilic, electrophilic, and radical regime Homologations realized on boron-containing or carbon-centered linchpins Use of highly sensitive fluorinated homologating agents Progressive homologations and the concept of assembly line synthesis Homologation processes followed by rearrangement cascades Construction of cyclic motifs and ring-expansion Homologation reactions with carbon monoxide and carbon dioxide New and/or challenging directions to expect in the future Written by an international team of leaders in the field, the book is a useful guide for designing effective transformations by using homologation reactions. It is a must-read for every synthetic chemist in academia and industry!

Graduate Aptitude Test [GPAT] Question Bank Book 22 Practice Sets [ Based on Online Test Series Pattern] As Per Updated Syllabus

Download Graduate Aptitude Test [GPAT] Question Bank Book 22 Practice Sets [ Based on Online Test Series Pattern] As Per Updated Syllabus PDF Online Free

Author :
Publisher : DIWAKAR EDUCATION HUB
ISBN 13 :
Total Pages : 621 pages
Book Rating : 4./5 ( download)

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Book Synopsis Graduate Aptitude Test [GPAT] Question Bank Book 22 Practice Sets [ Based on Online Test Series Pattern] As Per Updated Syllabus by : DIWAKAR EDUCATION HUB

Download or read book Graduate Aptitude Test [GPAT] Question Bank Book 22 Practice Sets [ Based on Online Test Series Pattern] As Per Updated Syllabus written by DIWAKAR EDUCATION HUB and published by DIWAKAR EDUCATION HUB . This book was released on 2022-03-24 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: Include 22 Test [10 Full Length [125 MCQ] + 12 Section Test MCQ] Pharmaceutical Chemistry – 3 Section Test 38 Questions Each Pharmaceutics – 3 Section Test 38 Questions Each Pharmacology – 3 Section Test 28 Questions Each Pharmacognosy – 3 Section Test 10 Questions Each Solution of Each question Given at the End of Each Set Based on Same Exam Pattern Like Online Test Series [ in Exam Hall] Most Expected Questions Chosen by Expert Faculties For More Details & Want to Practice Online Test Series in App or Web Call/Whats App - 7310762592,7078549303

USMLE Step 3 Lecture Notes 2019-2020

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Author :
Publisher : Kaplan Test Prep
ISBN 13 : 1506223176
Total Pages : 494 pages
Book Rating : 4.5/5 (62 download)

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Book Synopsis USMLE Step 3 Lecture Notes 2019-2020 by : Kaplan Medical

Download or read book USMLE Step 3 Lecture Notes 2019-2020 written by Kaplan Medical and published by Kaplan Test Prep. This book was released on 2019-01-01 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Always study with the most up-to-date prep! Look for USMLE Step 3 Lecture Notes 2021-2022, ISBN 9781506255255, on sale April 06, 2021. Publisher's Note: Products purchased from third-party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitles included with the product.

New Technical Books

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Publisher :
ISBN 13 :
Total Pages : 308 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis New Technical Books by : New York Public Library

Download or read book New Technical Books written by New York Public Library and published by . This book was released on 1925 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: