Author : Eric Reid
Publisher : Springer Science & Business Media
ISBN 13 : 1468444840
Total Pages : 281 pages
Book Rating : 4.4/5 (684 download)
Book Synopsis Drug Metabolite Isolation and Determination by : Eric Reid
Download or read book Drug Metabolite Isolation and Determination written by Eric Reid and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scope of the book, and acknowledgements.- The articles are focused on 'real problems' in body-fluid analysis, typically with a final chromatographic separation of ~g or often ng amounts if the aim is quantitation. The pitfalls may not be realized by a typical chemist (cf. remarks in #A-3), but he may excel in metabolite iden tification - which this book covers to a fair extent. Where identity is known, and the metabolite could interfere in therapeutic drug monitoring or in diagnosis or itself have clinical relevance, useful guidance will come from articles that follow. Authors have gone to much trouble, and are not to be blamed by any reader who would have liked an introduction to chromatography or to metabolic pathways (cf. list of conjugation reactions at end of concluding article). Appre ciation is also expressed for permission to reproduce published mat erial; the acknowledged sources include 1. Chroma tog. (Elsevier; e. g. in #A-l) , Anal. Chem. (American Chemical Society; #A-2) and Wiley.