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Drug Hepatotoxicity An Issue Of Clinics In Liver Disease
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Download or read book Drug-Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series
Book Synopsis Drug Hepatotoxicity, An Issue of Clinics in Liver Disease by : Nicholaos Pyrsopoulos
Download or read book Drug Hepatotoxicity, An Issue of Clinics in Liver Disease written by Nicholaos Pyrsopoulos and published by Elsevier Health Sciences. This book was released on 2013-12-28 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Pyrsopolous has created a comprehensive review on the most important and timely topics in drug heptatotoxicity. He has arraanged for there to be a full span of very basic articles that discuss drug metabolism, hepatotoxicity, and drug-induced acute liver failure as well as other important articles devoted to clinical manifestations and treatment of drug induced hepatotoxicity; Pathological manifestations of drug induced hepatotoxicity; Drug induced cholestasis; Lipid lowering agents induced hepatotoxicity; Herbal ,complementary and alternative medicine induced liver injury; Antiretroviral and anti - HCV DAA related hepatotoxicity; Antibiotic related hepatotoxicity; Acetaminophen related hepatoxicity; NSAIDS induced hepatoxocity; Chemotherapy induced hepatotoxicity; Anti epileptic induced hepatotoxicity; and steatohepatitis induced by drugs.
Book Synopsis Drug Hepatotoxicity,An Issue of Clinics in Liver Disease, E-Book by : Pierre Gholam
Download or read book Drug Hepatotoxicity,An Issue of Clinics in Liver Disease, E-Book written by Pierre Gholam and published by Elsevier Health Sciences. This book was released on 2019-12-03 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: In collaboration with Consulting Editor, Dr. Norman Gitlin, Dr. Pierre Gholam has put together topics that provide a current clinical update on the treatment and management of patients with drug-induced liver injury (DILI). Expert authors have contributed clinical review articles on the following topics: Epidemiology, Predisposing Factors and Outcomes; Genetic Predisposition to DILI; Causality Assessment Frequent Offenders and Patterns of Injury; Quantitative Systems Toxicology Approaches to Understand and Predict DILI; Liver Histology: Diagnostic and Prognostic Features; Acute Liver Failure Secondary to DILI; DILI in Persons with Pre-existing Chronic Liver Disease; DILI in the Setting of Statin Use; DILI in the Setting of Analgesic Use; DILI Secondary to Herbals and Dietary Supplements; and DILI Reporting and Resources for the Clinician. Readers will come away with the information they need to improve outcomes in patients with DILI.
Book Synopsis Drug Hepatotoxicity, An Issue of Clinics in Liver Disease by : Vinod K. Rustgi
Download or read book Drug Hepatotoxicity, An Issue of Clinics in Liver Disease written by Vinod K. Rustgi and published by Elsevier Health Sciences. This book was released on 2016-11-16 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Rustgi has assembled the leading experts in the management of Heptatitis B to present the current treatment and clinical course for diagnosis and management of the disease. Articles are devoted to: Drug metabolism in the liver; Mechanism of Liver Damage including the RUCAM scale; Drug-induced acute liver failure; Epidemiology and genetic risk factors; Adverse drug reactions: type A (intrinsic or pharmacological) or type B (idiosyncratic); Pathology of injury including phenotypes; The clinical course of drug-induced liver disease; Environmental factors of drug hepatotoxicity; Newer agents in drug hepatotoxicity; Drug hepatotoxicity: herbal products; Drug hepatotoxicity: models including “human on a chip and zebrafish; Acute and chronic liver failure from drugs: impact on the kidney; and Management of acute hepatotoxicity including medical agents and liver support systems. Readers will come away with the cutting edge science behind the latest innovations in the treatment of Hepatitis B.
Book Synopsis Pharmacokinetics and Adverse Effects of Drugs by : Ntambwe Malangu
Download or read book Pharmacokinetics and Adverse Effects of Drugs written by Ntambwe Malangu and published by BoD – Books on Demand. This book was released on 2018-05-23 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a fruit of a collaborative work from several international scientists. It will be a useful resource for researchers, students, and clinicians. Each individual chapter could serve as a prescribed reading for postgraduate students and clinicians specializing in and practicing clinical pharmacology and toxicology, pharmacotherapy and pharmacotherapeutics, pharmacovigilance, and toxicovigilance, as well as those involved in clinical research, drug discovery, and development. Every chapter in this book discusses and provides illustrations on the theme discussed based on authors' understanding and experience while summarizing existing knowledge. In doing so, each chapter provides a new insight that would benefit a novice as well as a seasoned reader in understanding the pharmacokinetic mechanisms and risk factors involved in the occurrence of adverse effects of drugs.
Book Synopsis Drug Hepatotoxicity, An Issue of Clinics in Liver Disease by : Nicholaos Pyrsopoulos
Download or read book Drug Hepatotoxicity, An Issue of Clinics in Liver Disease written by Nicholaos Pyrsopoulos and published by Elsevier Health Sciences. This book was released on 2013-10-16 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Pyrsopolous has created a comprehensive review on the most important and timely topics in drug heptatotoxicity. He has arraanged for there to be a full span of very basic articles that discuss drug metabolism, hepatotoxicity, and drug-induced acute liver failure as well as other important articles devoted to clinical manifestations and treatment of drug induced hepatotoxicity; Pathological manifestations of drug induced hepatotoxicity; Drug induced cholestasis; Lipid lowering agents induced hepatotoxicity; Herbal ,complementary and alternative medicine induced liver injury; Antiretroviral and anti - HCV DAA related hepatotoxicity; Antibiotic related hepatotoxicity; Acetaminophen related hepatoxicity; NSAIDS induced hepatoxocity; Chemotherapy induced hepatotoxicity; Anti epileptic induced hepatotoxicity; and steatohepatitis induced by drugs.
Book Synopsis Hepatitis B Virus, An Issue of Clinics in Liver Disease by : Tarek I. Hassanein
Download or read book Hepatitis B Virus, An Issue of Clinics in Liver Disease written by Tarek I. Hassanein and published by Elsevier Health Sciences. This book was released on 2019-07-06 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: In collaboration with Consulting Editor, Dr. Norman Gitlin, Dr. Tarek Hassanein has assembled top experts in hepatology to bring current information on the topic of Hepatitis B Virus. The issue provides the most current information on the prevention and care of infected patients. Specific articles are devoted to the following topics: Global perspective on HBV infections in the era of effective vaccines; Understanding the natural history of HBV infection and the new definitions of cure and the endpoints of clinical trials; HBV/HCV coinfection in the era of HCV-DAAs; Antiretroviral effects on HBV/HIV coinfection and the natural history of liver disease; Impact of HBV infection on HCC and liver transplantation; HBV in pregnant women and their infants; WHO guidelines for prevention, care and treatment of individuals infected with HBV: A US perspective; Reconciling the difference between the major HBV treatment guidelines: AASLD, EASL, APASL; HBV/HDV coinfection: A challenge for therapeutics; and The effects of hepatic steatosis on the natural history of HBV infection. Readers will come away with the current information they need to manage patient outcomes.
Book Synopsis Hepatitis B Virus, An Issue of Clinics in Liver Disease by : Tarik Asselah
Download or read book Hepatitis B Virus, An Issue of Clinics in Liver Disease written by Tarik Asselah and published by Elsevier Health Sciences. This book was released on 2013-08-28 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Guest Editors have assembled top international experts to present clinical reviews on the most current data being utilized in the diagnosis, treatment, and management of HBV. In fact, the most recent EASL meeting fndings are included in many of the articles. Special focus is given to Results of Treatment of Chronic Hepatitis B with Pegylated Interferon; Impact of Therapy on the Long Term Outcome of Chronic Hepatitis B; HBsAg Quantification: Clinical; HBV Infection and Hepatocellular Carcinoma; HIV-HBV Co-Infection: An Update; Hepatitis Delta: The Rediscovery; and Treatment of Patients with HBV Related Decompensated Cirrhosis and Liver Transplanted Patients
Book Synopsis Consultations in Liver Disease, An Issue of Clinics in Liver Disease by : Steven L. Flamm
Download or read book Consultations in Liver Disease, An Issue of Clinics in Liver Disease written by Steven L. Flamm and published by Elsevier Health Sciences. This book was released on 2017-10-11 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consultations of Gastroenterology practitioners are frequently sought for many complex issues relating to acute and chronic liver disease. Many of the disease entities are uncommon and complicated in scope. Liver disease may occur in the setting of other chronic medical conditions and involve other organ systems, with recommendations for diagnostic strategies and therapeutic approaches somewhat challenging. Serious consequences are often the rule with misdiagnosed or inadequately treated liver disease. Dr. Flamm has provided a framework for approaching consultation for common liver-related problems for the gastroenterology practitioner. Articles are devoted to the following topics: Common Findings and Interpretation for the Clinician; Genetic Testing in Liver Disease: What to Order and When; Acute Liver Failure; Liver Disease in Oncology Patients; Primary Sclerosing Cholangitis: What the Gastroenterologist/Hepatologist Needs to Know; An Update on the Treatment and Follow up of Patients with PBC; Wilson’s Disease: Diagnosis, Treatment, and Follow Up; Follow Up of the Post-Liver Transplantation Patient: A Primer for the Practicing Gastroenterologist; Liver Disease in Patients on Total Parenteral Nutrition; Treatment Strategies in NAFLD: What’s Coming; Resistance Testing in Chronic HCV; and HCV genotype 3: Treatment Approach and Natural History.
Book Synopsis Acute Liver Failure, An Issue of Clinics in Liver Disease by : Nikolaos T. Pyrsopoulos
Download or read book Acute Liver Failure, An Issue of Clinics in Liver Disease written by Nikolaos T. Pyrsopoulos and published by Elsevier Health Sciences. This book was released on 2018-04-13 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Pyrsopoulos has assembled the top authors in the field to provide current reviews on acute liver failure, to be the first time this topic is addressed in one volume. Topics are devoted to Classification and Epidemiologic Aspects of Acute Liver Failure; Acute Liver Failure: Mechanisms of disease and multi-systemic involvement; The Pathology of Acute Liver Failure; Liver Regeneration in the Acute Liver Failure Patient; Viral Hepatitis and Acute Liver Failure: Still a Problem; Drug- induced Liver Injury and Acute Liver Failure; Acetaminophen and Acute Liver Failure; Non-Viral Or Drug-Induced Etiologies of Acute Liver Failure; The Clinical Spectrum and Manifestations of Acute Liver Failure; Non ICU Management of Acute Liver Failure; Management of Acute Liver Failure in the ICU Setting; Prognostic Models of Acute Liver Failure; The Role of Liver Transplantation in Acute Liver Failure; and Future Approaches and Therapeutic Modalities for Acute Liver Failure. Readers will come away with a current point of view about how to approach and manage the patient with acute liver failure.
Book Synopsis Alcoholic Liver Disease, An Issue of Clinics in Liver Disease by : Stanley Cohen
Download or read book Alcoholic Liver Disease, An Issue of Clinics in Liver Disease written by Stanley Cohen and published by Elsevier Health Sciences. This book was released on 2016-07-15 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol abuse remains a significant problem world-wide. The most commonly affected organ remains the liver with a risk of alcoholic liver disease (ALD) which can range from asymptomatic to alcoholic hepatitis to alcoholic cirrhosis. In 2010, alcohol-attributable cirrhosis was responsible for 0.9% of all global deaths. Given the sheer magnitude of alcohol abuse and alcoholic liver disease, an update on this topic is pertinent and relevant. This issue will focus on a variety of topics including alcoholism, the pathogenesis of ALD, the spectrum of ALD, the pathology of ALD, and the long-term management of patients with ALD. Alcoholic hepatitis is a particular type of ALD with a high mortality. This issue will explore the syndrome of alcoholic hepatitis, its prognostic markers, and the available therapies. Because alcohol intake can influence so many other conditions of the liver (especially hepatitis C), articles in this issue will also explore the impact of alcohol abuse on other liver conditions. In addition, several other topics such as nutritional therapy for ALD, ALD and liver cancer, and ALD and infection risk will be explored. Also, even though it is quite controversial, we will also explore liver transplant as a therapy for alcoholic liver disease including alcoholic hepatitis.
Book Synopsis Liver in Systemic Diseases, An Issue of Clinics in Liver Disease by : Jorge Herrera
Download or read book Liver in Systemic Diseases, An Issue of Clinics in Liver Disease written by Jorge Herrera and published by Elsevier Health Sciences. This book was released on 2019-05-28 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: In consultation with Consulting Editor, Dr. Norman Gitlin, Dr. Jorge Herrera has put together a timely look at health and function of the liver in systemic diseases. The issue has all of the top experts in their field contributing conscise reviews of the following topics: The Liver in Celiac Disease; The Liver in Sickle Cell Disease; Hepatic Complications of Inflammatory Bowel Disease; The Liver in Circulatory Disturbances; Hepatobiliary Complications in Critically Ill Patients; Endocrine Diseases and the Liver; Rheumatologic Diseases and the Liver; Hepatic Manifestations of Cystic Fibrosis; Hepatic Complications of Total Parenteral Nutrition; Hepatic Manifestations of Lymphoproliferative Disorders; Liver Disease in HIV Infection; Sarcoidosis and the Liver; Liver Disease in Pregnancy; and Obstructive Sleep Apnea and the Liver.Readers will come away with the latest updates they need to improve outcomes in hepatology patients.
Book Synopsis Hepatic Encephalopathy, An Issue of Clinics in Liver Disease by : Vinod K. Rustgi
Download or read book Hepatic Encephalopathy, An Issue of Clinics in Liver Disease written by Vinod K. Rustgi and published by Elsevier Health Sciences. This book was released on 2020-05-11 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: In collaboration with Consulting Editor, Dr. Norman Gitlin, Dr. Vinod Rustgi has put together topics that provide a current clinical update on the treatment and management of patients with Hepatic Encephalopathy (HE). Experts in the field have contributetd clinical review articles on the following topics: Definition, Prevalence, and Epidemiology of HE; Pathophysiology of HE; Clinical Manifestations of HE; Laboratory Abnormalities of HE; Minimal or Subclinical HE; Prognosis of Prognosis of HE; Pharmacological Management of HE; Non-pharmacological Management of HE; Cost Burden of HE; Long-term management of HE: Modern Measures to Prevent Re-admission; Social Impact of HE; and Novel Therapies for HE. Readers will come away with the information they need to improve outcomes in patients with HE.
Book Synopsis Hepatotoxicity by : Hyman J. Zimmerman
Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Book Synopsis Cholestatic Liver Diseases, An Issue of Clinics in Liver Disease by : Cynthia Levy
Download or read book Cholestatic Liver Diseases, An Issue of Clinics in Liver Disease written by Cynthia Levy and published by Elsevier Health Sciences. This book was released on 2013-05-28 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Levy is a key leader in the field of hepatology , and she has enlisted authors who are top experts in their fields to submit state-of-the-art clinical reviews on cholestatic liver diseases. Articles are devoted to genetic determinants of cholestasis, nuclear receptors as drug targets, drug-induced cholestasis, primary sclerosing cholangitis, therapeutic advances in primary biliary cirrhosis, overlap syndromes, autoimmune sclerosing cholangitis, secondary sclerosing cholangitis, Focus is also on familial cholestasis, allagile syndrome and other hereditary causes of cholestasis, Systemic causes of cholestasis, advances in pathogenesis and treatment of pruritus, care of the cholestatic patient, and transplantation for cholestatic diseases . Readers will come away with a full overview of the diagnosis and treatment of cholestatic liver diseases.
Book Synopsis Liver Transplantation, An Issue of Clinics in Liver Disease by : Roberto J. Firpi
Download or read book Liver Transplantation, An Issue of Clinics in Liver Disease written by Roberto J. Firpi and published by Elsevier Health Sciences. This book was released on 2017-04-12 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cirrhosis from hepatitis C (HCV) is now the most common indication for liver transplant (LT) in the U.S., but between 2004 and 2013, new LT listings for NASH increased by 170%. Unfortunately, fibrosis progression leading to cirrhosis, liver cancer, and liver decompensation continues to occur after transplantation. Once cirrhosis and decompensation are evident, patient survival is poor and repeat LT is considered to improve outcomes. Therefore, the never-ending thirst for new approaches in the management of patients pre- and post-transplant has led to a very promising future in transplantation, thought there is much to learn to achieve better patient outcomes. This issue of Clinics in Liver Disease addresses the core areas to achieve better patient outcomes, with articles devoted to coagulopathy before liver transplant, challenges in renal failure before LT, LT for acute alcoholic hepatitis, LT in the pregnant patient, bariatric surgery and LT,and MELD Scores in prioritization of LT, to name a few. Readers will place a high value on the current state of liver transplantation in this issue.
Book Synopsis Approach to Consultations for Patients with Liver Disease, An Issue of Clinics in Liver Disease by : Steven L. Flamm
Download or read book Approach to Consultations for Patients with Liver Disease, An Issue of Clinics in Liver Disease written by Steven L. Flamm and published by Elsevier Health Sciences. This book was released on 2012-05-28 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: With very much success in 2009, this topic is being updated again in 2012. Dr. Flamm has invited a group of distinguished hepatologists to provide insight into the assessment of a variety of scenarios where clinical judgment based on experience and published literature is an invaluable addition to the care of individual patients. Articles included in the issue address the following topics: Evaluatio of Elevated Liver Enzymes and Abnormal Liver Panel; Evaluation of Liver Lesions; Chronic HCV; Evaluation of Hepatic Cholestasis; Chronic HBV; Ascites; Fatty Liver; Pruritus in the patient with chronic cholestatic liver disease; Is the patient a candidate for liver transplantation; Care of the cirrhotic patient; Abnormal liver panel in pregnancy; Surgical clearance for the patient with chronic liver disease; Granulomatous Liver Disease; Drug Induced Liver Disease; and Hepatic Encephalopathy.
