The Dopamine Receptors

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1603273336
Total Pages : 650 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis The Dopamine Receptors by : Kim Neve

Download or read book The Dopamine Receptors written by Kim Neve and published by Springer Science & Business Media. This book was released on 2009-12-01 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: As sites of action for drugs used to treat schizophrenia and Parkinson’s disease, dopamine receptors are among the most validated drug targets for neuropsychiatric disorders. Dopamine receptors are also drug targets or potential targets for other disorders such as substance abuse, depression, Tourette’s syndrome, and attention deficit hyperactivity disorder. Updated from the successful first edition, "The Dopamine Receptors" serves as a reference work on dopamine receptors while also highlighting the areas of research that are most active today. To achieve this goal, authors have written chapters that set a broad area of research in its historical context, rather than focusing on the research output of their own laboratories.

Encyclopedia of Movement Disorders

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Publisher : Academic Press
ISBN 13 : 012374105X
Total Pages : 1633 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Encyclopedia of Movement Disorders by :

Download or read book Encyclopedia of Movement Disorders written by and published by Academic Press. This book was released on 2010-02-26 with total page 1633 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Movement Disorders is a comprehensive reference work on movement disorders, encompassing a wide variety of topics in neurology, neurosurgery, psychiatry and pharmacology. This compilation will feature more than 300 focused entries, including sections on different disease states, pathophysiology, epidemiology, genetics, clinical presentation, diagnostic tools, as well as discussions on relevant basic science topics. This Encyclopedia is an essential addition to any collection, written to be accessible for both the clinical and non-clinical reader. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in the laboratory to the clinical features, pathophysiology and treatment of movement disorders. The Encyclopedia targets a broad readership, ranging from students to general physicians, basic scientists and Movement Disorder specialists. Published both in print and via Elsevier’s online platform of Science Direct, this Encyclopedia will have the enhanced option of integrating traditional print with online multimedia. Connects experimental findings made in the laboratory to the clinical features, pathophysiology, and treatment of movement disorders Encompasses a wide variety of topics in neurology neurosurgery, psychiatry, and pharmacology Written for a broad readership ranging from students to general physicians, basic scientists, and movement disorder specialists

Dopamine Receptors and Transporters

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Author :
Publisher : CRC Press
ISBN 13 : 0824747429
Total Pages : 663 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Dopamine Receptors and Transporters by : Anita Sidhu

Download or read book Dopamine Receptors and Transporters written by Anita Sidhu and published by CRC Press. This book was released on 2003-01-31 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Details the function, characterization, and physiology of various dopamine receptor/transporter systems and explores their role in etiology, diagnosis, and disease management."

Biology of the NMDA Receptor

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Publisher : CRC Press
ISBN 13 : 142004415X
Total Pages : 368 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Biology of the NMDA Receptor by : Antonius M. VanDongen

Download or read book Biology of the NMDA Receptor written by Antonius M. VanDongen and published by CRC Press. This book was released on 2008-10-29 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written

Central D1 Dopamine Receptors

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Author :
Publisher : Springer
ISBN 13 : 1489927239
Total Pages : 184 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Central D1 Dopamine Receptors by : M. J. Goldstein

Download or read book Central D1 Dopamine Receptors written by M. J. Goldstein and published by Springer. This book was released on 2013-11-21 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of a selective D1 dopamine (DA) receptor antagonist SCH 23390 stimulated a number of studies on the functions mediated by central DA receptor subtypes. It was generally assumed that the central D1 DA receptor isa molecular entity whose function awaits further discovery. The papers presented in this volume clearly show that this is no longer the case and that D1 DA receptors have many behavioral fuctions which might be altered in pathological states. A number of papers have recognized the interdependence of the regulatory functions of the D1 DA receptors with D2 and other receptor proteins, and vice versa. The biochemical, pharmacological and morphological characterization of the D1 and D2 DA receptor binding proteins, as well as of DARPP-32, illustrates the complex interactions between various macromolecules. Procedures described for the purification of the D1 and D2 DA receptor subtypes are fundamental for future studies on the mechanisms involved in the coupling of the receptor proteins with signal transducing systems. Several studies in this volume show that D1 DA receptors have behavioral functions and that they are often similar to the responses mediated by D2 DA receptors, but in some instances reflect divergent neuronal activity of both systems. The knowledge of the physiology and biochemistry of the central DA receptor subtypes could lead to the development of a new generation of drugs which ameliorate some mental and neurological dysfunctions without producing severe undesirable side effects.

Dopamine Receptors and Transporters

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Author :
Publisher : CRC Press
ISBN 13 :
Total Pages : 720 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Dopamine Receptors and Transporters by : Hyman B. Niznik

Download or read book Dopamine Receptors and Transporters written by Hyman B. Niznik and published by CRC Press. This book was released on 1994 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Details the function, characterization, and physiology of various dopamine receptor/transporter systems and explores their role in etiology, diagnosis, and disease management."

Dopamine Receptor Subtypes

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Publisher : IOS Press
ISBN 13 : 9789051992915
Total Pages : 200 pages
Book Rating : 4.9/5 (929 download)

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Book Synopsis Dopamine Receptor Subtypes by : Peter Jenner

Download or read book Dopamine Receptor Subtypes written by Peter Jenner and published by IOS Press. This book was released on 1998 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple subtypes of dopamine receptors exist in the brain. This volume reviews the characteristics of D-1, D-2, D-3 and D-4 receptors and describes the current concepts of their involvement in motor disorders and in the control of schizophrenia. Readers: the book will be of great interest to professionals in pharmacology, medicinal chemistry, neuroscience, cell biology and therapeutic applications in clinical medicine as antipsychotics, anti-Parkinson's disease and related areas.

Molecular Biology of G-Protein-Coupled Receptors

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Author :
Publisher : Birkhäuser
ISBN 13 : 9780817634650
Total Pages : 0 pages
Book Rating : 4.6/5 (346 download)

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Book Synopsis Molecular Biology of G-Protein-Coupled Receptors by : M. Brann

Download or read book Molecular Biology of G-Protein-Coupled Receptors written by M. Brann and published by Birkhäuser. This book was released on 1992-11-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: LESLIE L. IVERSEN The present series of volumes is well timed, as the impact of molecular genetics on pharmacology has been profound, and a comprehensive review of the rapid advances of the past decade is much needed. Since the pioneering work of Dale, Ariens, and others in the early years of this century, much of pharmacology has been founded on the concept of receptors. To begin with, the receptor was conceived of as a "black box," which recognized and transduced the biological effects of neurotransmit ters, hormones, or other biological messengers-and which could also represent a target for man-made drugs. It is only in the last two decades that "molecular pharmacology" has blossomed, first with the advent of radioligand binding techniques and second messenger studies which greatly facilitated the biochemical study of drug-receptor interactions, and latterly with increasing knowledge of the molecular architecture of the receptor proteins themselves. This started with the traditional biochemical approach of isolating and purifying the receptor molecules. This proved to be a task of immense technical difficulty because of the low density of receptors in most biological source tissues, although there were some notable successes, e. g. , the purification of the nicotinic acetylcholine receptor from the electric organ of Torpedo. It was the ap plication of molecular genetics technology during the 1980s, however, which really accelerated progress in this field.

Neurobiology of Central D1-Dopamine Receptors

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 146845191X
Total Pages : 223 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Neurobiology of Central D1-Dopamine Receptors by : George Breese

Download or read book Neurobiology of Central D1-Dopamine Receptors written by George Breese and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of the functional mechanisms relating dopamine activity to normal and abnormal behavior has been turned "upside-down" by the recent developments described in the chapters of this volume. Heretofore, it was generally agreed that all of the pharmacological and behavioral properties ascribed to dopamine systems were mediated via activation or inhibition of the subtype of dopamine receptors termed D2. The properties of these receptors were first characterized in 1975 following their identification by receptor binding techniques utilizing 3H-butyrophenones, potent antipsychotic drugs, used in the treatment of schizophrenia. Although another subtype of dopamine receptor had already been identified a few years earlier, now termed the Dl receptor, its functional properties were unknow- other than the fact that it was associated with the activation of the enzyme adenylate cyclase. Our absence of knowledge of the behavioral functions of this receptor stemmed primarily from the lack of selective agonist and antagonists for DI receptors - drugs which did not also interact with D2 receptors. Selective agents for D2 receptors did exist and hence the behavioral roles of D2 receptors were easily ascribed. The work described in this text is primarily stimulated by the development of two selective Dl receptor drugs - the antagonist SCH 23390 and the agonist SKF 38393. The studies described herein clearly show that D1 receptors do indeed have many behavioral functions, on the surface often similar to those responses mediated by D2 receptors.

The Neurobiology of Dopamine Systems

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Author :
Publisher : Manchester University Press
ISBN 13 : 9780719017995
Total Pages : 502 pages
Book Rating : 4.0/5 (179 download)

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Book Synopsis The Neurobiology of Dopamine Systems by : Northern Neurobiology Group (Great Britain). Symposium

Download or read book The Neurobiology of Dopamine Systems written by Northern Neurobiology Group (Great Britain). Symposium and published by Manchester University Press. This book was released on 1986 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dopamine in the CNS I

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Publisher : Springer Science & Business Media
ISBN 13 : 3642560512
Total Pages : 355 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Dopamine in the CNS I by : Gaetano Di Chiara

Download or read book Dopamine in the CNS I written by Gaetano Di Chiara and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts

The Role of Brain Dopamine

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Publisher : Springer Science & Business Media
ISBN 13 : 3642738974
Total Pages : 62 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Role of Brain Dopamine by :

Download or read book The Role of Brain Dopamine written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt: As in other volumes in the series, this newest volume conveys up-to-date knowledge in a clear and straightforward manner. It begins with a survey of the neurobiological functions of the brain, with the emphasis on Parkinson's disease. This is followed by a presentation of the role of dopamine in the regulation of human anterior pituitary function. The final two chapters concentrate on the dopamine receptors: first, the binding sites are characterized and the biochemical and physiological consequences of dopamine-receptor stimulation are discussed and, finally, there is a report on the topology of a dopamine-receptor model that can account comprehensively for agonists and antagonists.

Dopamine Receptors

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Publisher :
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Dopamine Receptors by : Ian Creese

Download or read book Dopamine Receptors written by Ian Creese and published by . This book was released on 1987 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Dopamine Receptors" precisely chronicles the research being done on dopamine receptors, appraises the techniques and strategies being used, and provides thoughts on future trends. This volume is unique for its multidisciplinary coverage of dopamine receptors, with contributions ranging from physiological and behavioral studies to the biological characterization of dopamine receptors. Examines classifications of receptor subtypes based on ligand binding and adenylate cyclase studies, biochemical analysis, electrophysiological observations and autoradiography. This book also summarizes dopamine receptor involvement in a number of diseases and covers the role of autoreceptors in modulation of dopaminergic systems.

Serotonin and Dopamine Receptors

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Publisher : Nova Biomedical Books
ISBN 13 : 9781536132168
Total Pages : 0 pages
Book Rating : 4.1/5 (321 download)

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Book Synopsis Serotonin and Dopamine Receptors by : Monica Munoz

Download or read book Serotonin and Dopamine Receptors written by Monica Munoz and published by Nova Biomedical Books. This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this compilation, the authors begin with a review of the mechanisms of synthesis and secretion, cellular effects and the involvement of serotonin (5-HT) in physiological and behavioral functions horses. In addition, the pathological conditions in which 5-HT is involved at the level of equine clinics are studied. Following this, the capabilities and limitations of PET imaging research on non-human primates are discussed for translation to brain DA research on humans, as well as therapeutic drug development for neurodegenerative diseases. This book also examines the etiology of autism spectrum disorder (ASD). The authors present available data contributing to the appreciation of a serotonergic dysfunction in ASD, as well as discuss new avenues to reveal the pathophysiology of this multifactorial disorder. Next, they review the historical and current evidence that links neurotransmitters with hemopoeitic stem cell mobilization, trafficking, and specially emphasize the role of serotonin in erythropoiesis. Potential actionable myelodysplastic and leukemic pathways are described and investigated.

Dopamine Receptors—Advances in Research and Application: 2012 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481609858
Total Pages : 74 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Dopamine Receptors—Advances in Research and Application: 2012 Edition by :

Download or read book Dopamine Receptors—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dopamine Receptors—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Dopamine Receptors in a concise format. The editors have built Dopamine Receptors—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Dopamine Receptors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Dopamine Receptors—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

CNS Neurotransmitters and Neuromodulators

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Publisher : CRC Press
ISBN 13 : 9780849376320
Total Pages : 280 pages
Book Rating : 4.3/5 (763 download)

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Book Synopsis CNS Neurotransmitters and Neuromodulators by : Trevor W. Stone

Download or read book CNS Neurotransmitters and Neuromodulators written by Trevor W. Stone and published by CRC Press. This book was released on 1996-05-09 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: CNS Neurotransmitters and Neuromodulators: Dopamine is an indispensable single-volume resource for any researcher involved with dopamine in the central nervous system (CNS). Part of the CNS Neurotransmitters and Neuromodulators Series, it is destined to be the definitive reference work on this topic. This book is comprised of independently authored chapters dealing with biochemistry, molecular biology and localization of dopamine receptors and transporters, receptor interactions, growth factors, new antipsychotic drugs, and the neuroendocrinal and retinal functions of dopamine. The authors, an international group of well-known researchers from varied disciplines, have utilized the most up-to-date material in preparing their reviews. CNS Neurotransmitters and Neuromodulators: Dopamine is the perfect source for established researchers seeking the latest information or for students requiring an in-depth one-step introduction.

Dopamine Receptor Agonists

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Publisher : Springer Science & Business Media
ISBN 13 : 1475703104
Total Pages : 402 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Dopamine Receptor Agonists by : George Poste

Download or read book Dopamine Receptor Agonists written by George Poste and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dopamine, in addition to its importance as a precursor of norepinephrine, is now known to be an important neurotransmitter in regulating functional activities in a number of major organ systems, including the central ner vous system. the cardiovascular system, the kidney, and the gut. Recent advances in our understanding of the functional role of dopamine, its mechanism of action and the pharmacology of dopaminergic agents have occurred on a broad front. The last few years have witnessed significant progress in the identification and classification of central and peripheral dopamine receptors and the factors that affect their responsiveness to inhibitory and stimulatory ligands. These advances have been paralleled by new insights into the contribution of alterations in dopaminergic reg ulation in causing disease and the utility of dopamine agonists and an tagonists as therapeutic modalities. This volume, the first in a series of publications arising from the annual Smith Kline and French Research Symposium on New Horizons in Therapeutics, provides a comprehensive survey of current research on peripheral dopamine receptors and the physiologic and therapeutic con sequences of stimulating pre-and postsynaptic dopamine receptors. Research in dopamine pharmacology mirrors the remarkable ad vances that are occurring in the field of pharmacology at large as a con sequence of the involvement of an ever-larger number of scientific dis ciplines in the study of drug action.