Dna Replication Control In Microbial Cell Factories

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DNA Replication Control in Microbial Cell Factories

Author : Monika Glinkowska
Publisher : Springer
ISBN 13 : 3319105337
Total Pages : 56 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis DNA Replication Control in Microbial Cell Factories by : Monika Glinkowska

Download or read book DNA Replication Control in Microbial Cell Factories written by Monika Glinkowska and published by Springer. This book was released on 2014-09-23 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in Escherichia coli, which focuses on the control of activity of the DnaA protein. Examples of direct linkages between DNA replication and other cellular processes are provided. In addition, similarities of the mechanisms of regulation of DNA replication operating in prokaryotic and eukaryotic cells are identified, and implications for understanding more complex processes, like carcinogenesis are suggested. Studies of recent years provided evidence that regulation of DNA replication in bacteria is more complex than previously anticipated. Multiple layers of control seem to ensure coordination of this process with the increase of cellular mass and the division cycle. Metabolic processes and membrane composition may serve as points where integration of genome replication with growth conditions occurs. It is also likely that coupling of DNA synthesis with cellular metabolism may involve interactions of replication proteins with other macromolecular complexes, responsible for various cellular processes. Thus, the exact set of factors participating in triggering the replication initiation may differ depending on growth conditions. Therefore, understanding the regulation of DNA duplication requires placing this process in the context of the current knowledge on bacterial metabolism, as well as cellular and chromosomal structure. Moreover, in both Escherichia coli and eukaryotic cells, replication initiator proteins were shown to play other roles in addition to driving the assembly of replication complexes, which constitutes another, yet not sufficiently understood, layer of coordinating DNA replication with the cell cycle.

Microbial Cell Factories Engineering for Production of Biomolecules

Author : Vijai Singh
Publisher : Academic Press
ISBN 13 : 0128214783
Total Pages : 490 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Microbial Cell Factories Engineering for Production of Biomolecules by : Vijai Singh

Download or read book Microbial Cell Factories Engineering for Production of Biomolecules written by Vijai Singh and published by Academic Press. This book was released on 2021-02-13 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. - Offers basic understanding and a clear picture of various MCFs - Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others - Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications - Highlights the advances, challenges, and future opportunities in designing MCFs

Metabolic Engineering

Author : Sang Yup Lee
Publisher : John Wiley & Sons
ISBN 13 : 352782345X
Total Pages : 1075 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Metabolic Engineering by : Sang Yup Lee

Download or read book Metabolic Engineering written by Sang Yup Lee and published by John Wiley & Sons. This book was released on 2021-06-02 with total page 1075 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn more about foundational and advanced topics in metabolic engineering in this comprehensive resource edited by leaders in the field Metabolic Engineering: Concepts and Applications delivers a one-stop resource for readers seeking a complete description of the concepts, models, and applications of metabolic engineering. This guide offers practical insights into the metabolic engineering of major cell lines, including E. Coli, Bacillus and Yarrowia Lipolytica, and organisms, including human, animal, and plant). The distinguished editors also offer readers resources on microbiome engineering and the use of metabolic engineering in bioremediation. Written in two parts, Metabolic Engineering begins with the essential models and strategies of the field, like Flux Balance Analysis, Quantitative Flux Analysis, and Proteome Constrained Models. It also provides an overview of topics like Pathway Design, Metabolomics, and Genome Editing of Bacteria and Eukarya. The second part contains insightful descriptions of the practical applications of metabolic engineering, including specific examples that shed light on the topics within. In addition to subjects like the metabolic engineering of animals, humans, and plants, you’ll learn more about: Metabolic engineering concepts and a historical perspective on their development The different modes of analysis, including flux balance analysis and quantitative flux analysis An illuminating and complete discussion of the thermodynamics of metabolic pathways The Genome architecture of E. coli, as well as genome editing of both bacteria and eukarya An in-depth treatment of the application of metabolic engineering techniques to organisms including corynebacterial, bacillus, and pseudomonas, and more Perfect for students of biotechnology, bioengineers, and biotechnologists, Metabolic Engineering: Concepts and Applications also has a place on the bookshelves of research institutes, biotechnological institutes and industry labs, and university libraries. It's comprehensive treatment of all relevant metabolic engineering concepts, models, and applications will be of use to practicing biotechnologists and bioengineers who wish to solidify their understanding of the field.

Molecular Biology, Pathogenicity, and Ecology of Bacterial Plasmids

Author : Stuart B. Levy
Publisher : Springer Science & Business Media
ISBN 13 : 1468439839
Total Pages : 692 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Molecular Biology, Pathogenicity, and Ecology of Bacterial Plasmids by : Stuart B. Levy

Download or read book Molecular Biology, Pathogenicity, and Ecology of Bacterial Plasmids written by Stuart B. Levy and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book resulted from presentations at an international conference on bacterial p1asmids held January 5-9, 1981 in Santo Domingo, Dominican Republic. This was the first meeting of its kind in the Southern Hemisphere. The meeting place was selected for its relaxed and comfortable climate, conducive to interactions among participants. More importantly the locale facilitated the participation of nearby Latin American clinical and research scientists who deal directly with the health manifestations of pathogenic p1asmids. Diseases and socio-economic practices of developing countries exist in the Dominican Republic whose scientific community could directly benefit from having the meeting there. The book includes the talks as well as extended abstracts of poster presentations from the meeting. This combination, which provides readers with reviews as well as recent findings, captures the full scientific exchange which took place during the 5-day meeting. As one indication of pathogenicity related to p1asmids, the conferees were surveyed for gastro-intestina1 problems during and after their stay in the Dominican Republic. The results are summarized at the end of this book.

Minimal Cells: Design, Construction, Biotechnological Applications

Author : Alvaro R. Lara
Publisher : Springer Nature
ISBN 13 : 3030318974
Total Pages : 233 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Minimal Cells: Design, Construction, Biotechnological Applications by : Alvaro R. Lara

Download or read book Minimal Cells: Design, Construction, Biotechnological Applications written by Alvaro R. Lara and published by Springer Nature. This book was released on 2019-12-04 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the design, generation and characterization of minimal cell systems. Written by leading experts, it presents an in-depth analysis of the current issues and challenges in the field, including recent advances in the generation and characterization of reduced-genome strains generated from model organisms with relevance in biotechnology, and basic research such as Escherichia coli, Corynebacterium glutamicum and yeast. It also discusses methodologies, such as bottom-up and top-down genome minimization strategies, as well as novel analytical and experimental approaches to characterize and generate minimal cells. Lastly, it presents the latest research related to minimal cells of serveral microorganisms, e.g. Bacillus subtilis. The design of biological systems for biotechnological purposes employs strategies aimed at optimizing specific tasks. This approach is based on enhancing certain biological functions while reducing other capacities that are not required or that could be detrimental to the desired objective. A highly optimized cell factory would be expected to have only the capacity for reproduction and for performing the expected task. Such a hypothetical organism would be considered a minimal cell. At present, numerous research groups in academia and industry are exploring the theoretical and practical implications of constructing and using minimal cells and are providing valuable fundamental insights into the characteristics of minimal genomes, leading to an understanding of the essential gene set. In addition, research in this field is providing valuable information on the physiology of minimal cells and their utilization as a biological chassis to which useful biotechnological functions can be added.

Biopolymers for Biomedical and Biotechnological Applications

Author : Bernd H. A. Rehm
Publisher : John Wiley & Sons
ISBN 13 : 3527818308
Total Pages : 400 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Biopolymers for Biomedical and Biotechnological Applications by : Bernd H. A. Rehm

Download or read book Biopolymers for Biomedical and Biotechnological Applications written by Bernd H. A. Rehm and published by John Wiley & Sons. This book was released on 2020-12-01 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides insight into biopolymers, their physicochemical properties, and their biomedical and biotechnological applications This comprehensive book is a one-stop reference for the production, modifications, and assessment of biopolymers. It highlights the technical and methodological advancements in introducing biopolymers, their study, and promoted applications. "Biopolymers for Biomedical and Biotechnological Applications" begins with a general overview of biopolymers, properties, and biocompatibility. It then provides in-depth information in three dedicated sections: Biopolymers through Bioengineering and Biotechnology Venues; Polymeric Biomaterials with Wide Applications; and Biopolymers for Specific Applications. Chapters cover: advances in biocompatibility; advanced microbial polysaccharides; microbial cell factories for biomanufacturing of polysaccharides; exploitation of exopolysaccharides from lactic acid bacteria; and the new biopolymer for biomedical application called nanocellulose. Advances in mucin biopolymer research are presented, along with those in the synthesis of fibrous proteins and their applications. The book looks at microbial polyhydroxyalkanoates (PHAs), as well as natural and synthetic biopolymers in drug delivery and tissue engineering. It finishes with a chapter on the current state and applications of, and future trends in, biopolymers in regenerative medicine. * Offers a complete and thorough treatment of biopolymers from synthesis strategies and physiochemical properties to applications in industrial and medical biotechnology * Discusses the most attracted biopolymers with wide and specific applications * Takes a systematic approach to the field which allows readers to grasp and implement strategies for biomedical and biotechnological applications "Biopolymers for Biomedical and Biotechnological Applications" appeals to biotechnologists, bioengineers, and polymer chemists, as well as to those working in the biotechnological industry and institutes.

Microbial Physiology

Author : Albert G. Moat
Publisher : John Wiley & Sons
ISBN 13 : 0471461199
Total Pages : 715 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Microbial Physiology by : Albert G. Moat

Download or read book Microbial Physiology written by Albert G. Moat and published by John Wiley & Sons. This book was released on 2003-03-31 with total page 715 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fourth Edition of Microbial Physiology retains the logical, easy-to-follow organization of the previous editions. An introduction to cell structure and synthesis of cell components is provided, followed by detailed discussions of genetics, metabolism, growth, and regulation for anyone wishing to understand the mechanisms underlying cell survival and growth. This comprehensive reference approaches the subject from a modern molecular genetic perspective, incorporating new insights gained from various genome projects.

Continuous Biomanufacturing

Author : Ganapathy Subramanian
Publisher : John Wiley & Sons
ISBN 13 : 3527699899
Total Pages : 632 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Continuous Biomanufacturing by : Ganapathy Subramanian

Download or read book Continuous Biomanufacturing written by Ganapathy Subramanian and published by John Wiley & Sons. This book was released on 2017-09-12 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive treatise of this topic available, providing invaluable information on the technological and economic benefits to be gained from implementing continuous processes in the biopharmaceutical industry. Top experts from industry and academia cover the latest technical developments in the field, describing the use of single-use technologies alongside perfusion production platforms and downstream operations. Special emphasis is given to process control and monitoring, including such topics as 'quality by design' and automation. The book is supplemented by case studies that highlight the enormous potential of continuous manufacturing for biopharmaceutical production facilities.

Fungal Cell Factories for Sustainable Nanomaterials Productions and Agricultural Applications

Author : Kamel A Abd-Elsalam
Publisher : Elsevier
ISBN 13 : 0323985505
Total Pages : 824 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Fungal Cell Factories for Sustainable Nanomaterials Productions and Agricultural Applications by : Kamel A Abd-Elsalam

Download or read book Fungal Cell Factories for Sustainable Nanomaterials Productions and Agricultural Applications written by Kamel A Abd-Elsalam and published by Elsevier. This book was released on 2022-10-26 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungal Cell Factories for Sustainable Nanomaterials Productions and Agricultural Applications explores the mycogenic synthesis of many metal nanoparticles, including processing processes, environmental protection, and future perspectives. Nanomaterials, including silver, gold, palladium, copper, zinc, selenium, titanium dioxide, metal sulphide, cellulose, have been formed by major fungal genes, such as mushrooms, Fusarium, Trichoderma, endophytic fungi, and yeast, in addition to lichens. Understanding the exact process involved in the synthesis of nanoparticles and the effects of various factors on the reduction of metal ions can help to improve low-cost strategies for the synthesis and extraction of nanoparticles. Other sections focus on a new framework for the production of nano-antimicrobial, the use of myconanoparticles against plant diseases, post-harvest antibiotics, mycotoxin control and plant pests in addition to certain animal pathogens. Myconanomaterials are well developed with great potential and promise for advanced diagnostics, biosensors, precision farming and targeted smart delivery systems. - Assesses the impact of a variety of copper-based nanostructures on agri-food sectors, addressing the most relevant knowledge gaps - Explores the opportunities that myconanotechnology can provide for industrial applications - Explains the major challenges of applying myconanotechnology at an industrial scale

Alcamo's Fundamentals of Microbiology

Author :
Publisher : Jones & Bartlett Publishers
ISBN 13 : 144961566X
Total Pages : 916 pages
Book Rating : 4.4/5 (496 download)

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Book Synopsis Alcamo's Fundamentals of Microbiology by :

Download or read book Alcamo's Fundamentals of Microbiology written by and published by Jones & Bartlett Publishers. This book was released on with total page 916 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Alcamo's Fundamentals of Microbiology

Author : Jeffrey C. Pommerville
Publisher : Jones & Bartlett Publishers
ISBN 13 : 1449655823
Total Pages : 916 pages
Book Rating : 4.4/5 (496 download)

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Book Synopsis Alcamo's Fundamentals of Microbiology by : Jeffrey C. Pommerville

Download or read book Alcamo's Fundamentals of Microbiology written by Jeffrey C. Pommerville and published by Jones & Bartlett Publishers. This book was released on 2010-08-10 with total page 916 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ninth edition of award-winning author Jeffrey Pommerville's classic text provides nursing and allied health students with a firm foundation in microbiology, with an emphasis on human disease. An educator himself, Dr. Pommerville incorporates accessible, engaging pedagogical elements and student-friendly ancillaries to help students maximize their understanding and retention of key concepts. Ideal for the non-major, the ninth edition includes numerous updates and additions, including the latest disease data and statistics, new material on emerging disease outbreaks, an expanded use of concept maps, and may other pedagogical features. With an inviting "Learning Design" format and Study Smart notes to students, Alcamo's Fundamentals of Microbiology, Ninth Edition ensures student success as they delve into the exciting world of microbiology.

The Science and Applications of Synthetic and Systems Biology

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309219396
Total Pages : 570 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis The Science and Applications of Synthetic and Systems Biology by : Institute of Medicine

Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Genetic Engineering of Plants

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309034345
Total Pages : 97 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Genetic Engineering of Plants by : National Research Council

Download or read book Genetic Engineering of Plants written by National Research Council and published by National Academies Press. This book was released on 1984-02-01 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The book...is, in fact, a short text on the many practical problems...associated with translating the explosion in basic biotechnological research into the next Green Revolution," explains Economic Botany. The book is "a concise and accurate narrative, that also manages to be interesting and personal...a splendid little book." Biotechnology states, "Because of the clarity with which it is written, this thin volume makes a major contribution to improving public understanding of genetic engineering's potential for enlarging the world's food supply...and can be profitably read by practically anyone interested in application of molecular biology to improvement of productivity in agriculture."

Horizons in Bioprocess Engineering

Author : Ravindra Pogaku
Publisher : Springer Nature
ISBN 13 : 3030290697
Total Pages : 354 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Horizons in Bioprocess Engineering by : Ravindra Pogaku

Download or read book Horizons in Bioprocess Engineering written by Ravindra Pogaku and published by Springer Nature. This book was released on 2019-10-12 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is divided into four parts that outline the use of science and technology for applications pertaining to chemical and bioprocess engineering. The book endeavors to help academia, researchers, and practitioners to use the principles and tools of Chemical and Bioprocess Engineering in a pertinent way, while attempting to point out the novel thoughts associated with the brain storming concepts encountered. As an example, the ability to use case studies appropriately is more important, to most practitioners.

Efficient biomanufacturing via microbial cell factories, volume II

Author : Wei Luo
Publisher : Frontiers Media SA
ISBN 13 : 2832534538
Total Pages : 189 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Efficient biomanufacturing via microbial cell factories, volume II by : Wei Luo

Download or read book Efficient biomanufacturing via microbial cell factories, volume II written by Wei Luo and published by Frontiers Media SA. This book was released on 2023-09-29 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Encyclopedia of Cell Biology

Author :
Publisher : Academic Press
ISBN 13 : 0123947960
Total Pages : 2972 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Encyclopedia of Cell Biology by :

Download or read book Encyclopedia of Cell Biology written by and published by Academic Press. This book was released on 2015-08-07 with total page 2972 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Cell Biology, Four Volume Set offers a broad overview of cell biology, offering reputable, foundational content for researchers and students across the biological and medical sciences. This important work includes 285 articles from domain experts covering every aspect of cell biology, with fully annotated figures, abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, the Encyclopedia of Cell Biology provides a fully cross-referenced, one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences. Fully annotated color images and videos for full comprehension of concepts, with layered content for readers from different levels of experience Includes information on cytokinesis, cell biology, cell mechanics, cytoskeleton dynamics, stem cells, prokaryotic cell biology, RNA biology, aging, cell growth, cell Injury, and more In-depth linking to Academic Press/Elsevier content and additional links to outside websites and resources for further reading A one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences

DNA Repair Mechanisms

Author : ICN Pharmaceuticals, inc
Publisher :
ISBN 13 :
Total Pages : 840 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis DNA Repair Mechanisms by : ICN Pharmaceuticals, inc

Download or read book DNA Repair Mechanisms written by ICN Pharmaceuticals, inc and published by . This book was released on 1978 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA Repair Mechanisms is an account of the proceedings at a major international conference on DNA Repair Mechanisms held at Keystone, Colorado on February 1978. The conference discusses through plenary sessions the overall standpoint of DNA repair. The papers presented and other important documents, such as short summaries by the workshop session conveners, comprise this book. The compilation describes the opposing views, those that agree and dispute about certain topic areas. This book, divided into 15 parts, is arranged according to the proceedings in the conference. The plenary sessions are ...