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Author : Niels Olsen Saraiva Camara
Publisher : Frontiers Media SA
ISBN 13 : 2832505147
Total Pages : 163 pages
Book Rating : 4.8/5 (325 download)
Download or read book DNA repair and immune response written by Niels Olsen Saraiva Camara and published by Frontiers Media SA. This book was released on 2023-01-27 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Feilong Meng
Publisher : Frontiers Media SA
ISBN 13 : 2889768856
Total Pages : 136 pages
Book Rating : 4.8/5 (897 download)
Download or read book DNA Repair Machinery in Innate and Adaptive Immunity written by Feilong Meng and published by Frontiers Media SA. This book was released on 2022-09-01 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Qiang Zhang
Publisher : Frontiers Media SA
ISBN 13 : 2832533841
Total Pages : 155 pages
Book Rating : 4.8/5 (325 download)
Download or read book Targeting DNA damage response to enhance antitumor innate immunity in radiotherapy written by Qiang Zhang and published by Frontiers Media SA. This book was released on 2023-09-08 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jean Krutmann
Publisher : Wiley-Blackwell
ISBN 13 : 9780865428263
Total Pages : 303 pages
Book Rating : 4.4/5 (282 download)
Download or read book Photoimmunology written by Jean Krutmann and published by Wiley-Blackwell. This book was released on 1995 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: The skin immune response/photoallergy/photoimmunology of lupus/UV & infectious disease/therapeutic photoimmunology.
Author : Eileen Parkes
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (117 download)
Download or read book The Immune Response to DNA Damage written by Eileen Parkes and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Nina Papavasiliou
Publisher : World Scientific
ISBN 13 : 1908977949
Total Pages : 232 pages
Book Rating : 4.9/5 (89 download)
Download or read book Dna Deamination And The Immune System: Aid In Health And Disease written by Nina Papavasiliou and published by World Scientific. This book was released on 2010-10-27 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the current understanding of the role of activation-induced cytidine deaminase (AID) in the generation of antibody response to antigenic challenge. Since the discovery of AID, and the genetic demonstration of its role in somatic hypermutation and class-switch recombination of antibody genes, much has been learned about the biochemistry of this enzyme. However, some key questions remain hotly contested, such as: how does this enzyme get to the antibody locus leaving the rest of the genome intact, and why are DNA repair pathways which normally repair deamination events co-opted into actually fixing mutations into the genome? These questions, among others, will be addressed in this monograph from various perspectives. Being leading experts in their respective fields, the contributors of this highly valued title summarize current research in the field of AID and put forth hypotheses in order to provide a platform for future experiments./a
Author :
Publisher : CSHL Press
ISBN 13 : 9780879696061
Total Pages : 680 pages
Book Rating : 4.6/5 (96 download)
Download or read book Biological Responses to DNA Damage written by and published by CSHL Press. This book was released on 2000 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Living cells have evolved many ways of coping with metabolic events and environmental influences that damage DNA. These mechanisms, and the frequent progression to cancer that results when they go awry, are rev iewed in this volume by authors from over sixty of the world's leading laboratories. The topics discussed include DNA repair, mutagenesis and other damage-tolerance functions, checkpoint control, apoptosis, and adaptation. They draw from studies on human and yeast cells. Current, but with a valuable historical perspective, this volume has the depth and lasting value typical of this most prestigious series and is esse ntial reading for investigators of DNA replication, cell cycle control, and tumorigenesis.
Author : P. Gopalakrishnakone
Publisher : Springer
ISBN 13 : 9789400764484
Total Pages : 502 pages
Book Rating : 4.7/5 (644 download)
Download or read book Microbial Toxins written by P. Gopalakrishnakone and published by Springer. This book was released on 2018-03-14 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.
Author : Hasan Muezzin
Publisher :
ISBN 13 :
Total Pages : 68 pages
Book Rating : 4.:/5 (643 download)
Download or read book DNA Damage Response and Molecular Recognition by the Innate Immune System written by Hasan Muezzin and published by . This book was released on 2007 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gillian Dunphy
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (16 download)
Download or read book The Cell-intrinsic Innate Immune Response to DNA Damage in Human Cells written by Gillian Dunphy and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rolf Jessberger
Publisher : Springer Science & Business Media
ISBN 13 : 3642501400
Total Pages : 329 pages
Book Rating : 4.6/5 (425 download)
Download or read book Molecular Analysis of DNA Rearrangements in the Immune System written by Rolf Jessberger and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vertebrate immune system is distinctive among defense systems of multicellular organisms. In addition to nonspecific immunity, it generates a randomized array of millions of antigen receptors (immunoglobulins and T-cell receptors). A subset of these receptors are critical for binding to invading microbes or biochemicals from them to tag the microbes for elimination. Three site-directed DNA modification processes are critical to this process in vertebrates. V(D)J recombination generates the array of exons that encode the antigen binding pockets. Recent work summarized in this volume describes the dissection of this process at the biochemical level. The mechanism of the reaction is now understood in considerable detail. The proteins that catalyze many steps of the process have now been identified by biochemical and genetic recon stitution and by analysis of genetic mutants defective in V(D)J recombination. Class switch recombination is the process by which the variable domain exon of the heavy chain is changed from IgM to IgG, IgA. or IgE. Recent progress is described in the de velopment of an extrachromosomal substrate assay system. Molecular genetic analysis of the process in transgenics is defining some of the cis sequence requirements. Biochemical assays for defining enzymatic components are also described. In addition to exciting progress in V(D)J recombination and class switch recombination, one chapter describes recent pro gress in somatic hypermutation.
Author : G. Pawelec
Publisher : Elsevier
ISBN 13 : 008054648X
Total Pages : 323 pages
Book Rating : 4.0/5 (85 download)
Download or read book Basic Biology and Clinical Impact of Immunosenescence written by G. Pawelec and published by Elsevier. This book was released on 2003-05-01 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ageing is of perennial interest as a universal feature in all human societies. The genetic background and biochemical bases of ageing processes are currently being revealed in unprecedented detail. It is emerging that one of the main hurdles to be overcome in achieving a long and healthy lifespan is the maintenance of a properly functioning immune system. The main cause of death in people who have achieved "successful ageing" (which mostly means not having succumbed to cancer or cardiovascular disease) is infectious disease, caused by immunosenescence. This book contains chapters by many of the leaders in the field of immune-related issues in ageing and remediation.
Author :
Publisher :
ISBN 13 : 9789493197114
Total Pages : 141 pages
Book Rating : 4.1/5 (971 download)
Download or read book Regulation of DNA Damage and Immune Response Pathways by Post-translational Protein Modification written by and published by . This book was released on 2020 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rodolphe Barrangou
Publisher : Springer Science & Business Media
ISBN 13 : 364234657X
Total Pages : 300 pages
Book Rating : 4.6/5 (423 download)
Download or read book CRISPR-Cas Systems written by Rodolphe Barrangou and published by Springer Science & Business Media. This book was released on 2012-12-13 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.
Author : Nadia Danilova
Publisher : Bentham Science Publishers
ISBN 13 : 9811437157
Total Pages : 459 pages
Book Rating : 4.8/5 (114 download)
Download or read book Stress Response and Immunity: Links and Trade Offs written by Nadia Danilova and published by Bentham Science Publishers. This book was released on 2020-02-04 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: When environmental conditions deviate from the optimal range, stress ensues. Stress response is a set of reactions that allow the organism to adjust and survive adverse conditions. Stress can be physical, such as extreme temperature, radiation, injury, or psychological, caused by perceived danger or deprivation. Every living cell has biochemical mechanisms to cope with physical stress. These mechanisms show a degree of similarity among several types of living organisms. Stress Response and Immunity: Links and Trade Offs explores the functional and evolutionary connections between stress response and immunity. The book introduces the reader to the concept of stress and subsequently examines the connection between stress response and immunity at various evolutionary stages of living organisms - from bacteria to humans. The book also features chapters dedicated to the role of tumor suppressor genes and the immune system of the brain. The information presented in this reference demonstrates the profound effects of physical and psychological stress on human health. Readers with basic knowledge of molecular biology will learn about the interesting facets of stress responses and the evolutionary trade offs observed in different life forms.
Author : Blossom Damania
Publisher : Springer Science & Business Media
ISBN 13 : 0387689451
Total Pages : 805 pages
Book Rating : 4.3/5 (876 download)
Download or read book DNA Tumor Viruses written by Blossom Damania and published by Springer Science & Business Media. This book was released on 2008-12-19 with total page 805 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book focuses on the DNA viruses in the human population that are associated with cancers. It covers most of the viruses that are thought to contribute to human malignancy. This book represents a comprehensive review of the field of DNA tumor virology. Right now, while there are books out there that cover individual viruses that are also covered in this book, there is no single book that covers this topic comprehensively. This book is the first current, comprehensive review of its kind in the market.
Author :
Publisher : Academic Press
ISBN 13 : 0128155604
Total Pages : 386 pages
Book Rating : 4.1/5 (281 download)
Download or read book DNA Repair written by and published by Academic Press. This book was released on 2019-02-22 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA Repair, Volume 115, the latest release in the Advances in Protein Chemistry and Structural Biology series, provides an overview of current developments in mechanisms underlying DNA repair, their involvement in maintaining chromatin repair, the balance between chromosome breaks repair pathways, tumorigenesis, immune signaling and infection-induced inflammation. Specific chapters cover the Structure and function of the multi-subunit TFIIH with insights into nucleotide excision repair, Chromatin repair: how DNA packaging controls double-strand break repair, Controlling the balance between chromosome breaks repair pathways, The targeting of DNA repair pathways in the era of precision oncology, and much more. - Describes advances in our understanding on DNA repair mechanisms and the involvement of their dysregulation in promoting diseases - Presents data that is targeted to a very wide audience of specialists, researchers and students - Contains timely chapters written by well-renowned authorities in their field - Provides targeted information that is well supported by a number of high-quality illustrations, figures and tables
