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A Handbook for DNA-Encoded Chemistry

Author : Robert A. Goodnow, Jr.
Publisher : John Wiley & Sons
ISBN 13 : 1118487680
Total Pages : 495 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis A Handbook for DNA-Encoded Chemistry by : Robert A. Goodnow, Jr.

Download or read book A Handbook for DNA-Encoded Chemistry written by Robert A. Goodnow, Jr. and published by John Wiley & Sons. This book was released on 2014-04-28 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available “chemical space” for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods

DNA Handbook

Author : Cecilia Mary Hageman
Publisher :
ISBN 13 : 9780433456360
Total Pages : 274 pages
Book Rating : 4.4/5 (563 download)

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Book Synopsis DNA Handbook by : Cecilia Mary Hageman

Download or read book DNA Handbook written by Cecilia Mary Hageman and published by . This book was released on 2008 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: "DNA evidence is now commonplace in criminal trials, due to rapid advances in sophisticated analysis technology. These developments also mean that DNA has tremendous value in quasi-criminal and civil matters, such as clarifying family relationships and identifying senders of private or confidential communications. Regardless of the scenario, DNA evidence is highly legislated and subject to rigorous procedures and standards."--pub. desc.

Regenesis

Author : George M Church
Publisher : Basic Books
ISBN 13 : 0465038654
Total Pages : 305 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis Regenesis by : George M Church

Download or read book Regenesis written by George M Church and published by Basic Books. This book was released on 2014-04-08 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Harvard biologist and master inventor explores how new biotechnologies will enable us to bring species back from the dead, unlock vast supplies of renewable energy, and extend human life. In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies-far from the out-of-control nightmare depicted in science fiction-have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

Your DNA Guide - the Book

Author : Diahan Southard
Publisher :
ISBN 13 : 9781734613902
Total Pages : 250 pages
Book Rating : 4.6/5 (139 download)

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Book Synopsis Your DNA Guide - the Book by : Diahan Southard

Download or read book Your DNA Guide - the Book written by Diahan Southard and published by . This book was released on 2020-02-26 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: You don't have to learn everything about genetic genealogy before asking specific questions of your DNA! That's the premise of Diahan Southard's brand new book, Your DNA Guide - the Book, now available for pre-order at a special sale price. Your DNA Guide - the Book is like no other genetic genealogy book on the market. Instead of learning more-than-you-need-to-know in textbook style, you'll choose a specific DNA question to start exploring right away. You'll follow concrete step-by-step plans, learning important DNA concepts--in plain English--as you go. Do you want to learn who your 2X great grandmother is? Turn to page 23. Do you want to know how you are related to one of your DNA matches? Page 37. As you proceed, you check your progress and get new guidance based on your specific results at each stage. (Including troubleshooting, like when your matches just aren't responding or your great-grandparents turn out to be first cousins.) This powerful, hands-on approach is based on Diahan's 20 years of experience in the genetic genealogy industry and especially in the past five years, as she helps clients one-on-one make DNA discoveries. It became clear to her that while each client's situation may be unique, there are patterns in how you can find solutions that you can apply yourself. Your DNA Guide - the Book is for anyone who has taken a DNA test or may want to. It helps genealogists reconstruct family trees. It helps adoptees identify biological relatives. It can help you identify a specific DNA match. In short, it helps anyone explore what their DNA--and their DNA matches--can tell them about their origins.

DNA Handbook

Author : Cecilia Mary Hageman
Publisher :
ISBN 13 : 9780433437666
Total Pages : 245 pages
Book Rating : 4.4/5 (376 download)

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Book Synopsis DNA Handbook by : Cecilia Mary Hageman

Download or read book DNA Handbook written by Cecilia Mary Hageman and published by . This book was released on 2002 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Understanding DNA

Author : Chris R. Calladine
Publisher : Elsevier
ISBN 13 : 0080474667
Total Pages : 349 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Understanding DNA by : Chris R. Calladine

Download or read book Understanding DNA written by Chris R. Calladine and published by Elsevier. This book was released on 2004-03-13 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: The functional properties of any molecule are directly related to, and affected by, its structure. This is especially true for DNA, the molecular that carries the code for all life on earth. The third edition of Understanding DNA has been entirely revised and updated, and expanded to cover new advances in our understanding. It explains, step by step, how DNA forms specific structures, the nature of these structures and how they fundamentally affect the biological processes of transcription and replication. Written in a clear, concise and lively fashion, Understanding DNA is essential reading for all molecular biology, biochemistry and genetics students, to newcomers to the field from other areas such as chemistry or physics, and even for seasoned researchers, who really want to understand DNA. Describes the basic units of DNA and how these form the double helix, and the various types of DNA double helix Outlines the methods used to study DNA structure Contains over 130 illustrations, some in full color, as well as exercises and further readings to stimulate student comprehension

Handbook of Epigenetics

Author : Trygve O Tollefsbol
Publisher : Academic Press
ISBN 13 : 0128054778
Total Pages : 684 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Handbook of Epigenetics by : Trygve O Tollefsbol

Download or read book Handbook of Epigenetics written by Trygve O Tollefsbol and published by Academic Press. This book was released on 2017-07-10 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue and organ regeneration, X-chromosome inactivation, stem cell differentiation, genomic imprinting, and aging. The first edition of this important work received excellent reviews; the second edition continues its comprehensive coverage adding more current research and new topics based on customer and reader reviews, including new discoveries, approved therapeutics, and clinical trials. From molecular mechanisms and epigenetic technology, to discoveries in human disease and clinical epigenetics, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics, to therapeutic interventions for epigenetic-based disorders. Timely and comprehensive collection of fully up-to-date reviews on epigenetics that are organized into one volume and written by leading figures in the field Covers the latest advances in many different areas of epigenetics, ranging from basic aspects, to technologies, to clinical medicine Written at a verbal and technical level that can be understood by scientists and college students Updated to include new epigenetic discoveries, newly approved therapeutics, and clinical trials

Forensic DNA Biology

Author : Kelly M. Elkins
Publisher : Academic Press
ISBN 13 : 0123945852
Total Pages : 226 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Forensic DNA Biology by : Kelly M. Elkins

Download or read book Forensic DNA Biology written by Kelly M. Elkins and published by Academic Press. This book was released on 2012-09-11 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of forensic DNA typing laboratory experiments designed for academic and training courses at the collegiate level.

The Nucleic Acid Protocols Handbook

Author : Ralph Rapley
Publisher : Springer Science & Business Media
ISBN 13 : 1592590381
Total Pages : 997 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis The Nucleic Acid Protocols Handbook by : Ralph Rapley

Download or read book The Nucleic Acid Protocols Handbook written by Ralph Rapley and published by Springer Science & Business Media. This book was released on 2008-06-29 with total page 997 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive treasury of all the key molecular biology methods-ranging from DNA extraction to gene localization in situ-needed to function effectively in the modern laboratory. Each of the 120 highly successful techniques follows the format of the much acclaimed Methods in Molecular BiologyOao series, providing an introduction to the scientific basis of each technique, a complete listing of all the necessary materials and reagents, and clear step-by-step instruction to permit error-free execution. Included for each technique are notes about pitfalls to avoid, troubleshooting tips, alternate methods, and explanations of the reasons for certain steps-all key elements contributing significantly to success or failure in the lab. The Nucleic Acid Protocols Handbook constitutes today's most comprehensive collection of all the key classic and cutting-edge techniques for the successful isolation, analysis, and manipulation of nucleic acids by both experienced researchers and those new to the field."

DNA Structure and Function

Author : Richard R. Sinden
Publisher : Elsevier
ISBN 13 : 0080571735
Total Pages : 423 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis DNA Structure and Function by : Richard R. Sinden

Download or read book DNA Structure and Function written by Richard R. Sinden and published by Elsevier. This book was released on 2012-12-02 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA Structure and Function, a timely and comprehensive resource, is intended for any student or scientist interested in DNA structure and its biological implications. The book provides a simple yet comprehensive introduction to nearly all aspects of DNA structure. It also explains current ideas on the biological significance of classic and alternative DNA conformations. Suitable for graduate courses on DNA structure and nucleic acids, the text is also excellent supplemental reading for courses in general biochemistry, molecular biology, and genetics. Explains basic DNA Structure and function clearly and simply Contains up-to-date coverage of cruciforms, Z-DNA, triplex DNA, and other DNA conformations Discusses DNA-protein interactions, chromosomal organization, and biological implications of structure Highlights key experiments and ideas within boxed sections Illustrated with 150 diagrams and figures that convey structural and experimental concepts

The DNA Book

Author : DK
Publisher : Dorling Kindersley Ltd
ISBN 13 : 0241466008
Total Pages : 72 pages
Book Rating : 4.2/5 (414 download)

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Book Synopsis The DNA Book by : DK

Download or read book The DNA Book written by DK and published by Dorling Kindersley Ltd. This book was released on 2020-05-07 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's inside every living plant and animal, from the tiniest seed to the person standing next to you, but how much do you know about DNA? From why we have different coloured eyes to why we age, this book gives children an in-depth look at DNA and its role in all living things. Discover what DNA is, what it does, and how it shapes our lives, including inheritance and why we look like our parents; forensic science and how DNA evidence helps catch criminals; and how genetic engineering could theoretically bring dinosaurs back to life. With fun illustrated characters, clear diagrams, and fascinating photographs, children will love learning about themselves and this all-important molecule. The DNA Book is packed with colourful illustrations and mind-boggling facts, a great addition to any STEAM library. Perfect for curious young minds, this is an ideal introduction to the amazing science of genetics, and what makes you you.

DNA Technology

Author : David E. Newton
Publisher :
ISBN 13 : 9781598843286
Total Pages : 0 pages
Book Rating : 4.8/5 (432 download)

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Book Synopsis DNA Technology by : David E. Newton

Download or read book DNA Technology written by David E. Newton and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise, authoritative source that explores the latest advances and potential uses of DNA, as well as the ethical dilemmas surrounding the altering of genetic material. Authoritative and accessible, DNA Technology: A Reference Handbook discusses the scientific developments that have contributed to our current understanding of DNA and the wide application of such technology in numerous fields. DNA Technology explores early scientists whose work laid the foundation for Watson and Crick's groundbreaking paper, as well as subsequent researchers who have furthered our knowledge of DNA. Readers will see how DNA technology is used to catch criminals, exonerate prisoners, identify disorders, produce more effective drugs, and enhance food production. Beyond explaining the science, the book also addresses the ethical, legal, economic, and social concerns that have been raised over the power to alter life, and gives readers context and background to think through these issues for themselves. - Includes a range of primary sources including tables on genetically modified crops, position papers written by nongovernmental organizations, laws, and regulations in the United States and elsewhere in the world - Offers a listing of the most important terms used in a discussion of DNA technologies

Handbook of DNA Profiling

Author : Hirak Ranjan Dash
Publisher : Springer
ISBN 13 : 9789811643170
Total Pages : 1206 pages
Book Rating : 4.6/5 (431 download)

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Book Synopsis Handbook of DNA Profiling by : Hirak Ranjan Dash

Download or read book Handbook of DNA Profiling written by Hirak Ranjan Dash and published by Springer. This book was released on 2022-06-29 with total page 1206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference book comprehensively reviews the significance of DNA technology in forensic science. After presenting the theory, basic principles, tools and techniques that are used in forensic DNA typing, it summarizes various techniques, including autosomal STR, Y-STR, X-STR, mitochondrial DNA and NGS, used in solving both criminal as and civil cases, such as paternity disputes, identification of mutilated remains, and culprit identification in sexual assault and murder cases. It also provides an overview of DNA-based genetic diagnostics for various diseases, and discusses the role of DNA typing in drug reactions, as well as the application of non-human DNA profiling of animals and plants in forensic science investigations. Lastly, the book examines the role of internal quality control in maintaining the high quality of DNA profiling.

Junk DNA

Author : Nessa Carey
Publisher : Icon Books
ISBN 13 : 184831826X
Total Pages : 376 pages
Book Rating : 4.8/5 (483 download)

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Book Synopsis Junk DNA by : Nessa Carey

Download or read book Junk DNA written by Nessa Carey and published by Icon Books. This book was released on 2015-03-05 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the author of the acclaimed The Epigenetics Revolution (‘A book that would have had Darwin swooning’ – Guardian) comes another thrilling exploration of the cutting edge of human science. For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions – 98% of the human genome – were dismissed as ‘junk’. But in recent years researchers have discovered that variations in this ‘junk’ DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them. Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. She shows how junk DNA plays an important role in areas as diverse as genetic diseases, viral infections, sex determination in mammals, human biological complexity, disease treatments, even evolution itself – and reveals how we are only now truly unlocking its secrets, more than half a century after Crick and Watson won their Nobel prize for the discovery of the structure of DNA in 1962.

DNA Technology

Author : David E. Newton
Publisher : Bloomsbury Publishing USA
ISBN 13 :
Total Pages : 229 pages
Book Rating : 4.2/5 (16 download)

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Book Synopsis DNA Technology by : David E. Newton

Download or read book DNA Technology written by David E. Newton and published by Bloomsbury Publishing USA. This book was released on 2016-12-12 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This accessibly written book introduces readers to DNA—one of the most important technologies for the manipulation of all forms of life, from simple bacteria to plants and animals. It also addresses the most important social, ethical, political, economic, and other issues raised by this form of technology. The great strides made in our understanding of the structure and function of DNA in recent decades have led to applying this invaluable knowledge to use in serving humanity. For example, recent discoveries in the field of genetic editing have created the potential for the creation of life forms de novo, a possibility that results in profound ethical issues for the human race that are just beginning to be discussed. What other positive—and potentially negative—developments are coming our way with continuing advancements in DNA research? DNA Technology: A Reference Handbook provides an up-to-date historical overview and general technical background to the topic as well as a broad introduction to current issues related to the development of DNA technology, such as genetically modified organisms, the use of DNA technology in the forensic sciences, and genetic testing and genetic therapy. Written by David E. Newton, an author and former teacher who has dedicated a lifetime to authoring educational texts on science and technology, this book examines the history of DNA technology from its discovery in the 1950s to the present day and covers recent advances, such as new methods for gene editing, including CRISP-Cas9 technology. Readers need to have little or no background knowledge of the technology of genetic engineering to improve their understanding of DNA-based technologies and how DNA research influences many current issues and debates in agriculture, food science, forensics, public health, and other fields. The single-volume work is particularly well-suited to students and young adults because of the range of references included that serve further study, such as a glossary of terms, a chronology, and an extensive annotated bibliography.

Handbook of the Biology of Aging

Author : Nicolas Musi
Publisher : Academic Press
ISBN 13 : 0124116205
Total Pages : 576 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Handbook of the Biology of Aging by : Nicolas Musi

Download or read book Handbook of the Biology of Aging written by Nicolas Musi and published by Academic Press. This book was released on 2015-08-20 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of the Biology of Aging, Eighth Edition, provides readers with an update on the rapid progress in the research of aging. It is a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology, and focuses on the trend of ‘big data’ approaches in the biological sciences, presenting new strategies to analyze, interpret, and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and the metabolomics methodologies applied to aging related problems. The book includes discussions on longevity pathways and interventions that modulate aging, innovative new tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, new strategies to pharmacologically modulate the mTOR pathway to delay aging, the importance of sirtuins and the hypoxic response in aging, and how various pathways interact within the context of aging as a complex genetic trait, amongst others. Covers the key areas in biological gerontology research in one volume, with an 80% update from the previous edition Edited by Matt Kaeberlein and George Martin, highly respected voices and researchers within the biology of aging discipline Assists basic researchers in keeping abreast of research and clinical findings outside their subdiscipline Presents information that will help medical, behavioral, and social gerontologists in understanding what basic scientists and clinicians are discovering New chapters on genetics, evolutionary biology, bone aging, and epigenetic control Provides a close examination of the diverse research being conducted today in the study of the biology of aging, detailing recent breakthroughs and potential new directions

Mobile DNA III

Author : Michael Chandler
Publisher : John Wiley & Sons
ISBN 13 : 1555819214
Total Pages : 1321 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Mobile DNA III by : Michael Chandler

Download or read book Mobile DNA III written by Michael Chandler and published by John Wiley & Sons. This book was released on 2020-07-24 with total page 1321 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exploration of the raw power of genetic material to refashion itself to any purpose... Virtually all organisms contain multiple mobile DNAs that can move from place to place, and in some organisms, mobile DNA elements make up a significant portion of the genome. Mobile DNA III provides a comprehensive review of recent research, including findings suggesting the important role that mobile elements play in genome evolution and stability. Editor-in-Chief Nancy L. Craig assembled a team of multidisciplinary experts to develop this cutting-edge resource that covers the specific molecular mechanisms involved in recombination, including a detailed structural analysis of the enzymes responsible presents a detailed account of the many different recombination systems that can rearrange genomes examines the tremendous impact of mobile DNA in virtually all organisms Mobile DNA III is valuable as an in-depth supplemental reading for upper level life sciences students and as a reference for investigators exploring new biological systems. Biomedical researchers will find documentation of recent advances in understanding immune-antigen conflict between host and pathogen. It introduces biotechnicians to amazing tools for in vivo control of designer DNAs. It allows specialists to pick and choose advanced reviews of specific elements and to be drawn in by unexpected parallels and contrasts among the elements in diverse organisms. Mobile DNA III provides the most lucid reviews of these complex topics available anywhere.