Differing Routes to Stem Cell Research

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Publisher :
ISBN 13 :
Total Pages : 284 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Differing Routes to Stem Cell Research by : Renato Giuseppe Mazzolini

Download or read book Differing Routes to Stem Cell Research written by Renato Giuseppe Mazzolini and published by . This book was released on 2012 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells have been in the center of a heated biomedical and biopolitical debate in the first decade of the new millennium. Ethical concerns prevailed. The present volume follows the controversial discussions on stem cells in Italy and Germany, respectively, over the past 15 years. It aims at an assessment of the situation, and its method is comparative. The first part of the book takes a step back and sheds light on the early history of views on stem cells and on cellular reprogramming from the middle of the nineteenth to the end of the twentieth century. Part two and three have a close look on the recent developments in Germany and in Italy from three different viewpoints: the state of the art in scientific research, the public debate on its perceived promises and dangers, and the political and legal regulations that followed. It turns out that, despite their cultural and geographical vicinity, there are significant national differences in the discursive and juridical strategies followed in both European countries.

Stem Cells and the Future of Regenerative Medicine

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Publisher : National Academies Press
ISBN 13 : 0309170427
Total Pages : 112 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Stem Cells and the Future of Regenerative Medicine by : Institute of Medicine

Download or read book Stem Cells and the Future of Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Stem Cells: Current Challenges and New Directions

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Publisher : Springer Science & Business Media
ISBN 13 : 1461480663
Total Pages : 379 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Stem Cells: Current Challenges and New Directions by : Kursad Turksen

Download or read book Stem Cells: Current Challenges and New Directions written by Kursad Turksen and published by Springer Science & Business Media. This book was released on 2013-09-24 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume looks at the state-of-the-science in stem cells, discusses the current challenges, and examines the new directions the field is taking. Dr. Turksen, editor-in-chief of the journal "Stem Cell Reviews and Reports," has assembled a volume of internationally-known scientists who cover topics that are both clinically and research-oriented. The contents range from sources of stem cells through their physiological role in health and disease, therapeutic applications in regenerative medicine, and ethics and society. An initial overview and a final summary bookend the contents into a cohesive and invaluable volume.

A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics

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Author :
Publisher : Academic Press
ISBN 13 : 0128119217
Total Pages : 548 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics by : Xiao-Dong Chen

Download or read book A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics written by Xiao-Dong Chen and published by Academic Press. This book was released on 2018-08-31 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Roadmap to Non-hematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic is a resource that provides an overview of the principles of stem cell therapy, the promises and challenges of using stem cells for treating various clinical conditions, and future perspectives. The overall goal is to facilitate the translation of basic research on stem cells to clinical applications. The properties of stem cells from various sources are reviewed and the advantages and disadvantages of each for clinical use are discussed. Modifying stem cell properties through preconditioning strategies using physical, chemical, genetic, and molecular manipulation to improve cell survival, increase cell differentiation potential, enhance production of paracrine factors, and facilitate homing to the site of injury or disease upon transplantation are reviewed. Various routes of stem cell administration and dosing, and the duration of effects, are explored. Individual chapters are written by experts in the field and focus on the use of stem cells in treating various degenerative diseases, autoimmune diseases, wound healing, cardiovascular disease, spinal cord injury, oral and dental diseases, and skeletal disorders. Finally, experts in the regulatory arena discuss mechanisms used in different countries for approving the use of stem cells to treat diseases and many common issues that are typically encountered while seeking approval for this class of therapeutic agent. - Offers advanced students, as well as new researchers, an overview of the principles of stem cell therapy - Discusses a wide array of pressing clinical issues with stem cell-based therapies so that new ideas in the laboratory can be efficiently translated to the clinic through better designed clinical trials - Helps clarify current regulatory mechanisms so that the safe use of stem cells for treating a variety of diseases can move forward - Fosters cross-disciplinary dialogue between research scientists and physicians to accelerate the safe implementation of efficacious cell therapies

Differing Routes to Stem Cell Research

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Author :
Publisher :
ISBN 13 :
Total Pages : 276 pages
Book Rating : 4.:/5 (891 download)

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Book Synopsis Differing Routes to Stem Cell Research by : Renato Giuseppe Mazzolini

Download or read book Differing Routes to Stem Cell Research written by Renato Giuseppe Mazzolini and published by . This book was released on 2012 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells have been in the center of a heated biomedical and biopolitical debate in the first decade of the new millennium. Ethical concerns prevailed. The present volume follows the controversial discussions on stem cells in Italy and Germany, respectively, over the past 15 years. It aims at an assessment of the situation, and its method is comparative. The first part of the book takes a step back and sheds light on the early history of views on stem cells and on cellular reprogramming from the middle of the nineteenth to the end of the twentieth century. Part two and three have a close look on the recent developments in Germany and in Italy from three different viewpoints: the state of the art in scientific research, the public debate on its perceived promises and dangers, and the political and legal regulations that followed. It turns out that, despite their cultural and geographical vicinity, there are significant national differences in the discursive and juridical strategies followed in both European countries.

Human Embryonic Stem Cells

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Author :
Publisher : Springer Science & Business Media
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Human Embryonic Stem Cells by : Arlene Chiu

Download or read book Human Embryonic Stem Cells written by Arlene Chiu and published by Springer Science & Business Media. This book was released on 2003-08 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.

Stem Cells

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Publisher : Cambridge University Press
ISBN 13 : 1108663176
Total Pages : 149 pages
Book Rating : 4.1/5 (86 download)

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Book Synopsis Stem Cells by : Melinda Bonnie Fagan

Download or read book Stem Cells written by Melinda Bonnie Fagan and published by Cambridge University Press. This book was released on 2021-05-27 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is a stem cell? The answer is seemingly obvious: a cell that is also a stem, or point of origin, for something else. Upon closer examination, however, this combination of ideas leads directly to fundamental questions about biological development. A cell is a basic category of living thing; a fundamental 'unit of life.' A stem is a site of growth; an active source that supports or gives rise to something else. Both concepts are deeply rooted in biological thought, with rich and complex histories. The idea of a stem cell unites them, but the union is neither simple nor straightforward. This book traces the origins of the stem cell concept, its use in stem cell research today, and implications of the idea for stem cell experiments, their concrete results, and hoped-for clinical advances.

Stem Cell Manufacturing

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Publisher : Elsevier
ISBN 13 : 0444632662
Total Pages : 342 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Stem Cell Manufacturing by : Joaquim M.S. Cabral

Download or read book Stem Cell Manufacturing written by Joaquim M.S. Cabral and published by Elsevier. This book was released on 2016-07-24 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cell Manufacturing discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product. The advent of stem cell research unveiled the therapeutic potential of stem cells and their derivatives and increased the awareness of the public and scientific community for the topic. The successful manufacturing of stem cells and their derivatives is expected to have a positive impact in the society since it will contribute to widen the offer of therapeutic solutions to the patients. Fully defined cellular products can be used to restore the structure and function of damaged tissues and organs and to develop stem cell-based cellular therapies for the treatment of cancer and hematological disorders, autoimmune and other inflammatory diseases and genetic disorders. - Presents the first 'Flowchart' of stem cell manufacturing enabling easy understanding of the various processes in a sequential and coherent manner - Covers all bioprocess technologies required for the transfer of the bench findings to the clinic including the process components: cell signals, bioreactors, modeling, automation, safety, etc. - Presents comprehensive coverage of a true multidisciplinary topic by bringing together specialists in their particular area - Provides the basics of the processes and identifies the issues to be resolved for large scale cell culture by the bioengineer - Addresses the critical need in bioprocessing for the successful delivery of stem cell technology to the market place by involving professional engineers in sections of the book

Stem Cells: From Basic Research to Therapy, Volume 1

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Author :
Publisher : CRC Press
ISBN 13 : 1482207761
Total Pages : 670 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Stem Cells: From Basic Research to Therapy, Volume 1 by : Federico Calegari

Download or read book Stem Cells: From Basic Research to Therapy, Volume 1 written by Federico Calegari and published by CRC Press. This book was released on 2014-02-07 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first volume of Stem Cells deals with the fundamental principles that govern embryonic and somatic stem cell biology. Historically, the identification and characterization of such pathways and general rules of stemness occurred during embryonic development and Volume I reflects this with topics spanning cell cycle regulation, epigenetics, and a

The Third Lens

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Publisher : University of Chicago Press
ISBN 13 : 022656343X
Total Pages : 278 pages
Book Rating : 4.2/5 (265 download)

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Book Synopsis The Third Lens by : Andrew S. Reynolds

Download or read book The Third Lens written by Andrew S. Reynolds and published by University of Chicago Press. This book was released on 2018-06-21 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Does science aim at providing an account of the world that is literally true or objectively true? Understanding the difference requires paying close attention to metaphor and its role in science. In The Third Lens, Andrew S. Reynolds argues that metaphors, like microscopes and other instruments, are a vital tool in the construction of scientific knowledge and explanations of how the world works. More than just rhetorical devices for conveying difficult ideas, metaphors provide the conceptual means with which scientists interpret and intervene in the world. Reynolds here investigates the role of metaphors in the creation of scientific concepts, theories, and explanations, using cell theory as his primary case study. He explores the history of key metaphors that have informed the field and the experimental, philosophical, and social circumstances under which they have emerged, risen in popularity, and in some cases faded from view. How we think of cells—as chambers, organisms, or even machines—makes a difference to scientific practice. Consequently, an accurate picture of how scientific knowledge is made requires us to understand how the metaphors scientists use—and the social values that often surreptitiously accompany them—influence our understanding of the world, and, ultimately, of ourselves. The influence of metaphor isn’t limited to how we think about cells or proteins: in some cases they can even lead to real material change in the very nature of the thing in question, as scientists use technology to alter the reality to fit the metaphor. Drawing out the implications of science’s reliance upon metaphor, The Third Lens will be of interest to anyone working in the areas of history and philosophy of science, science studies, cell and molecular biology, science education and communication, and metaphor in general.

Investigating Interdisciplinary Collaboration

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Publisher : Rutgers University Press
ISBN 13 : 0813585910
Total Pages : 260 pages
Book Rating : 4.8/5 (135 download)

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Book Synopsis Investigating Interdisciplinary Collaboration by : Scott Frickel

Download or read book Investigating Interdisciplinary Collaboration written by Scott Frickel and published by Rutgers University Press. This book was released on 2016-11-25 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interdisciplinarity has become a buzzword in academia, as research universities funnel their financial resources toward collaborations between faculty in different disciplines. In theory, interdisciplinary collaboration breaks down artificial divisions between different departments, allowing more innovative and sophisticated research to flourish. But does it actually work this way in practice? Investigating Interdisciplinary Collaboration puts the common beliefs about such research to the test, using empirical data gathered by scholars from the United States, Canada, and Great Britain. The book’s contributors critically interrogate the assumptions underlying the fervor for interdisciplinarity. Their attentive scholarship reveals how, for all its potential benefits, interdisciplinary collaboration is neither immune to academia’s status hierarchies, nor a simple antidote to the alleged shortcomings of disciplinary study. Chapter 10 is available Open Access here (https://www.ncbi.nlm.nih.gov/books/NBK395883)

Encyclopedia of Stem Cell Research

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Publisher : SAGE Publications
ISBN 13 : 1452265933
Total Pages : 953 pages
Book Rating : 4.4/5 (522 download)

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Book Synopsis Encyclopedia of Stem Cell Research by : Clive N. Svendsen

Download or read book Encyclopedia of Stem Cell Research written by Clive N. Svendsen and published by SAGE Publications. This book was released on 2008-08-12 with total page 953 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is a stem cell? We have a basic working definition, but the way we observe a stem cell function in a dish may not represent how it functions in a living organism. Only this is clear: Stem cells are the engine room of multicelluar organisms—both plants and animals. However, controversies, breakthroughs, and frustration continue to swirl in eternal storms through this rapidly moving area of research. But what does the average person make of all this, and how can an interested scholar probe this vast sea of information? The Encyclopedia of Stem Cell Research provides a clear understanding of the basic concepts in stem cell biology and addresses the politics, ethics, and challenges currently facing the field. While stem cells are exciting alone, they are also clearly fueling the traditional areas of developmental biology and the field of regenerative medicine. These two volumes present more than 320 articles that explore major topics related to the emerging science of stem cell research and therapy. Key Features · Describes the different types of stem cells that have been reported so far and, where possible, tries to explain for each age, tissue, and species what is known about the biology of the cells and their history · Captures a strong sense of stem cell biology as it stands today and provides the reader with a reference manual to probe the mysteries of the field · Considers various religious, legal, and political perspectives · Includes selected reprints of major journal articles that pertain to the milestones achieved in stem cell research · Elucidates stem cell terminology for the nonscientist. Key Themes · Biology · Clinical Trials · Countries · Diseases · Ethics · History and Technology · Industry · Institutions · Legal · Organizations · People · Politics · Religion · States With contributions from scholars and institutional experts in the stem cell and social sciences, this Encyclopedia provides a primarily nonscientific resource to understanding the complexities of stem cell research for academic and public libraries.

Adult and Embryonic Stem Cells

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1617796298
Total Pages : 267 pages
Book Rating : 4.6/5 (177 download)

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Book Synopsis Adult and Embryonic Stem Cells by : Kursad Turksen

Download or read book Adult and Embryonic Stem Cells written by Kursad Turksen and published by Springer Science & Business Media. This book was released on 2012-02-03 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will cover a series of reviews on stem cells including adult and embryonic stem cells. Speakers were invited to present these talks during the Stem Cell Symposia in fall of 2010, in Samsun, Turkey. Unique aspect of this volume is that it brings a multidisciplinary aspect of stem cells extracted from a symposium.

Differentiation of Embryonic Stem Cells

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Author :
Publisher : Elsevier
ISBN 13 : 0080546161
Total Pages : 577 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Differentiation of Embryonic Stem Cells by :

Download or read book Differentiation of Embryonic Stem Cells written by and published by Elsevier. This book was released on 2003-12-18 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers all aspects of embryonic stem cell differentiation, including mouse embryonic stem cells, mouse embryonic germ cells, monkey and human embryonic stem cells, and gene discovery.* Early commitment steps and generation of chimeric mice* Differentiation to mesoderm derivatives* Gene discovery by manipulation of mouse embryonic stem cells

Encyclopedia of Stem Cell Research

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Author :
Publisher : SAGE
ISBN 13 : 141295908X
Total Pages : 953 pages
Book Rating : 4.4/5 (129 download)

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Book Synopsis Encyclopedia of Stem Cell Research by :

Download or read book Encyclopedia of Stem Cell Research written by and published by SAGE. This book was released on 2008 with total page 953 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Provides an understanding of the basic concepts in stem cell biology and addresses the politics, ethics, and challenges currently facing the field"--From publisher description.

Stem Cells: From Basic Research to Therapy, Volume Two

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Author :
Publisher : CRC Press
ISBN 13 : 1482219840
Total Pages : 474 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Stem Cells: From Basic Research to Therapy, Volume Two by : Federico Calegari

Download or read book Stem Cells: From Basic Research to Therapy, Volume Two written by Federico Calegari and published by CRC Press. This book was released on 2016-04-19 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second volume in the Stem Cells series concentrates on the mechanisms of stem cell regeneration in the adult organism with a view towards understanding how lost tissue can be replaced during adulthood and aging. The second focus of this volume is on stem cell identification and manipulation, including applications in basic research, medicine, a

The Matrix of Stem Cell Research

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Author :
Publisher : Routledge
ISBN 13 : 1351597930
Total Pages : 343 pages
Book Rating : 4.3/5 (515 download)

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Book Synopsis The Matrix of Stem Cell Research by : Christine Hauskeller

Download or read book The Matrix of Stem Cell Research written by Christine Hauskeller and published by Routledge. This book was released on 2019-07-25 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cell research has been a problematic endeavour. For the past twenty years it has attracted moral controversies in both the public and the professional sphere. The research involves not only laboratories, clinics and people, but ethics, industries, jurisprudence, and markets. Today it contributes to the development of new therapies and affects increasingly many social arenas. The matrix approach introduced in this book offers a new understanding of this science in its relation to society. The contributions are multidisciplinary and intersectional, illustrating how agency and influence between science and society go both ways. Conceptually, this volume presents a situated and reflexive approach for philosophy and sociology of the life sciences. The practices that are part of stem cell research are dispersed, and the concepts that tie them together are tenuous; there are persistent problems with the validation of findings, and the ontology of the stem cell is elusive. The array of applications shapes a growing bioeconomy that is dependent on patient donations of tissues and embryos, consumers, and industrial support. In this volume it is argued that this research now denotes not a specific field but a flexible web of intersecting practices, discourses, and agencies. To capture significant parts of this complex reality, this book presents recent findings from researchers, who have studied in-depth aspects of this matrix of stem cell research. This volume presents state-of-the-art examinations from senior and junior scholars in disciplines from humanities and laboratory research to various social sciences, highlighting particular normative and epistemological intersections. The book will appeal to scholars as well as wider audiences interested in developments in life science and society interactions. The novel matrix approach and the accessible case studies make this an excellent resource for science and society courses.