Developments And Applications In Solubility

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Development and Applications in Solubility

Author : Trevor M. Letcher
Publisher : Royal Society of Chemistry
ISBN 13 : 0854043721
Total Pages : 433 pages
Book Rating : 4.8/5 (54 download)

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Book Synopsis Development and Applications in Solubility by : Trevor M. Letcher

Download or read book Development and Applications in Solubility written by Trevor M. Letcher and published by Royal Society of Chemistry. This book was released on 2007 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solubility is fundamental to most areas of chemistry and is one of the most basic of thermodynamic properties. It underlies most industrial processes. Bringing together the latest developments and ideas, Developments and Applications in Solubility covers many varied and disparate topics. The book is a collection of work from leading experts in their fields and covers the theory of solubility, modelling and simulation, industrial applications and new data and recent developments relating to solubility. Of particular interest are sections on: experimental, calculated and predicted solubilities; solubility phenomena in 'green' quaternary mixtures involving ionic liquids; molecular simulation approaches to solubility; solubility impurities in cryogenic liquids and carbon dioxide in chemical processes. The book is a definitive and comprehensive reference to what is new in solubility and is ideal for researcher scientists, industrialists and academics

Developments and Applications in Solubility

Author : Trevor M Letcher
Publisher : Royal Society of Chemistry
ISBN 13 : 1847557686
Total Pages : 432 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Developments and Applications in Solubility by : Trevor M Letcher

Download or read book Developments and Applications in Solubility written by Trevor M Letcher and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solubility is fundamental to most areas of chemistry and is one of the most basic of thermodynamic properties. It underlies most industrial processes. Bringing together the latest developments and ideas, Developments and Applications in Solubility covers many varied and disparate topics. The book is a collection of work from leading experts in their fields and covers the theory of solubility, modelling and simulation, industrial applications and new data and recent developments relating to solubility. Of particular interest are sections on: experimental, calculated and predicted solubilities; solubility phenomena in 'green' quaternary mixtures involving ionic liquids; molecular simulation approaches to solubility; solubility impurities in cryogenic liquids and carbon dioxide in chemical processes. The book is a definitive and comprehensive reference to what is new in solubility and is ideal for researcher scientists, industrialists and academics

Thermodynamics, Solubility and Environmental Issues

Author : Trevor Letcher
Publisher : Elsevier
ISBN 13 : 0080481035
Total Pages : 494 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Thermodynamics, Solubility and Environmental Issues by : Trevor Letcher

Download or read book Thermodynamics, Solubility and Environmental Issues written by Trevor Letcher and published by Elsevier. This book was released on 2007-04-20 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental problems are becoming an important aspect of our lives as industries grow apace with populations throughout the world. Thermodynamics, Solubility and Environmental Issues highlights some of the problems and shows how chemistry can help to reduce these them. The unifying theme is Solubility – the most basic and important of thermodynamic properties. This informative book looks at the importance and applications of solubility and thermodynamics, in understanding and in reducing chemical pollution in the environment. Written by experts in their respective fields and representing the latest findings in this very important and broad area. A collection of twenty-five chapters cover a wide range of topics including; mining, polymer manufacture and applications, radioactive wastes, industries in general, agro-chemicals, soil pollution and biology, together with the basic theory and recent developments in the modelling of environmental pollutants. Latest research into solving some of the most important environmental problems Covering new technologies, new chemicals and new processes eg, biodegradable polymers, ionic liquids and green chemistry Contains the basic theories and underlying importance of solubility

Recent Developments in the Synthesis and Applications of Pyridines

Author : Parvesh Singh
Publisher : Elsevier
ISBN 13 : 0323914594
Total Pages : 650 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Recent Developments in the Synthesis and Applications of Pyridines by : Parvesh Singh

Download or read book Recent Developments in the Synthesis and Applications of Pyridines written by Parvesh Singh and published by Elsevier. This book was released on 2022-09-17 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Developments in the Synthesis and Applications of Pyridines is a comprehensive handbook for organic chemists working on innovative approaches to the synthesis of pyridines. Written by scientists in both academia and industry and designed to be a standalone reference, the book features reviews, research results and case studies on synthetic methods and applications of pyridine-based chemotypes. The book will bridge the gap between industry and academia by presenting recent innovative approaches to the synthesis of pyridines, diverse application of pyridines in drug development, heterogeneous catalysis and material science, as well as benchtop to shelf narratives of pyridine-based compounds in the industry. The role of computational chemistry in the development of pyridine-based bioactive molecules is also included. This reference is essential for researchers in organic chemistry both in academic and industrial settings, postgraduates in chemistry and medicinal chemistry. Includes a detailed review of recent research on the reactivity, synthesis and applications of pyridines Features concise accounts of the reactivity, synthetic and optimized protocols Discusses the medicinal, inorganic and polymer chemistry applications of pyridines

Biopharmaceutics Applications in Drug Development

Author : Rajesh Krishna
Publisher : Springer Science & Business Media
ISBN 13 : 038772379X
Total Pages : 416 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Biopharmaceutics Applications in Drug Development by : Rajesh Krishna

Download or read book Biopharmaceutics Applications in Drug Development written by Rajesh Krishna and published by Springer Science & Business Media. This book was released on 2007-09-20 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The highly experienced authors here present readers with step-wise, detail-conscious information to develop quality pharmaceuticals. The book is made up of carefully crafted sections introducing key concepts and advances in the areas of dissolution, BA/BE, BCS, IVIC, and product quality. It provides a specific focus on the integration of regulatory considerations and includes case histories highlighting the biopharmaceutics strategies adopted in development of successful drugs.

Dosage Forms, Formulation Developments and Regulations

Author : Amit Kumar Nayak
Publisher : Elsevier
ISBN 13 : 0323972462
Total Pages : 759 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Dosage Forms, Formulation Developments and Regulations by : Amit Kumar Nayak

Download or read book Dosage Forms, Formulation Developments and Regulations written by Amit Kumar Nayak and published by Elsevier. This book was released on 2023-12-09 with total page 759 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dosage Forms, Formulation Developments and Regulations, Volume One in the Recent and Future Trends in Pharmaceutics series, explores aspects of pharmaceutics, with an original approach focused on technology, novelties and future trends in the field. The book discusses the most recent developments in pharmaceutical preformulation and formulation studies, biopharmaceutics and novel pharmaceutical formulations, regulatory affairs, and good manufacturing practices. Exciting areas such as formulation strategies, optimization techniques, the biopharmaceutical classification system, and pharmaceutical aerosols are included. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day, so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. This is an essential reference for researchers in academia and industry as well as advanced graduate students in pharmaceutics. Examines trends and recent technologies in dosage, formulation and regulation Contains contributions from leading experts in academia, research, industry and regulatory agencies Includes high-quality illustrations, flow charts and tables for easy understanding of concepts Discusses practical examples and research case studies

Water Soluble Polymers

Author : Zahid Amjad
Publisher : Springer Science & Business Media
ISBN 13 : 0306469154
Total Pages : 261 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Water Soluble Polymers by : Zahid Amjad

Download or read book Water Soluble Polymers written by Zahid Amjad and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains a series of papers originally presented at the symposium on Water Soluble Polymers: Solution Properties and Applications, sponsored by the Division of Colloids and Surface Chemistry of the American Chemical Society. The symposium took place in Las Vegas City, Nevada on 9 to 11th September, 1997 at the 214th American Chemical Society National Meeting. Recognized experts in their - spective fields were invited to speak. There was a strong attendance from academia, g- ernment, and industrial research centers. The purpose of the symposium was to present and discuss recent developments in the solution properties of water soluble polymers and their applications in aqueous systems. Water soluble polymers find applications in a number of fields of which the following may be worth mentioning: cosmetics, detergent, oral care, industrial water treatment, g- thermal, wastewater treatment, water purification and reuse, pulp and paper production, sugar refining, and many more. Moreover, water soluble polymers play vital role in the oil industry, especially in enhanced oil recovery. Water soluble polymers are also used in ag- culture and controlled release pharmaceutical applications. Therefore, a fundamental kno- edge of solution properties of these polymers is essential for most industrial scientists. An understanding of the basic phenomena involved in the application of these polymers, such as adsorption and interaction with different substrates (i. e. , tooth enamel, hair, reverse - mosis membrane, heat exchanger surfaces, etc. ) is of vital importance in developing high performance formulations for achieving optimum efficiency of the system.

Rapid Throughput Solubility Screening Assay Development and Its Applications in Preformulation

Author : Jeremy Guo
Publisher :
ISBN 13 : 9781109888102
Total Pages : 179 pages
Book Rating : 4.8/5 (881 download)

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Book Synopsis Rapid Throughput Solubility Screening Assay Development and Its Applications in Preformulation by : Jeremy Guo

Download or read book Rapid Throughput Solubility Screening Assay Development and Its Applications in Preformulation written by Jeremy Guo and published by . This book was released on 2007 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: The method was then used to evaluate the solubilities of Biopharmaceutic Classification Scheme (BCS) class II drugs in animal and simulated human GI fluids. The goal was to establish correlates between in vitro and in vivo drug solubility in the GI tract. Four BCS class II drugs with solubilities ranging from a few mug/mL to over 100 mug/mL were evaluated in simulated GI fluid in both fasted and fed conditions. Method reproducibility was within 15% relative standard deviation. Solubility values from the screening method correlated well with literature values.

Development and Application of Bituminous Materials for Civil Infrastructures

Author : Hui Yao
Publisher : Frontiers Media SA
ISBN 13 : 2889715418
Total Pages : 214 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Development and Application of Bituminous Materials for Civil Infrastructures by : Hui Yao

Download or read book Development and Application of Bituminous Materials for Civil Infrastructures written by Hui Yao and published by Frontiers Media SA. This book was released on 2021-10-22 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Computer Applications in Pharmaceutical Research and Development

Author : Sean Ekins
Publisher : John Wiley & Sons
ISBN 13 : 0470037229
Total Pages : 840 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Computer Applications in Pharmaceutical Research and Development by : Sean Ekins

Download or read book Computer Applications in Pharmaceutical Research and Development written by Sean Ekins and published by John Wiley & Sons. This book was released on 2006-07-11 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique, holistic approach covering all functions and phases of pharmaceutical research and development While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery, development, and marketing. It explains how applications are used at various stages, including bioinformatics, data mining, predicting human response to drugs, and high-throughput screening. By providing a comprehensive view, the book offers readers a unique framework and systems perspective from which they can devise strategies to thoroughly exploit the use of computers in their organizations during all phases of the discovery and development process. Chapters are organized into the following sections: * Computers in pharmaceutical research and development: a general overview * Understanding diseases: mining complex systems for knowledge * Scientific information handling and enhancing productivity * Computers in drug discovery * Computers in preclinical development * Computers in development decision making, economics, and market analysis * Computers in clinical development * Future applications and future development Each chapter is written by one or more leading experts in the field and carefully edited to ensure a consistent structure and approach throughout the book. Figures are used extensively to illustrate complex concepts and multifaceted processes. References are provided in each chapter to enable readers to continue investigating a particular topic in depth. Finally, tables of software resources are provided in many of the chapters. This is essential reading for IT professionals and scientists in the pharmaceutical industry as well as researchers involved in informatics and ADMET, drug discovery, and technology development. The book's cross-functional, all-phases approach provides a unique opportunity for a holistic analysis and assessment of computer applications in pharmaceutics.

CRC Handbook of Solubility Parameters and Other Cohesion Parameters

Author : Allan F.M. Barton
Publisher : Routledge
ISBN 13 : 1351457195
Total Pages : 768 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis CRC Handbook of Solubility Parameters and Other Cohesion Parameters by : Allan F.M. Barton

Download or read book CRC Handbook of Solubility Parameters and Other Cohesion Parameters written by Allan F.M. Barton and published by Routledge. This book was released on 2017-10-19 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: The CRC Handbook of Solubility Parameters and Other Cohesion Parameters, Second Edition, which includes 17 new sections and 40 new data tables, incorporates information from a vast amount of material published over the last ten years. The volume is based on a bibliography of 2,900 reports, including 1,200 new citations. The detailed, careful construction of the handbook develops the concept of solubility parameters from empirical, thermodynamic, and molecular points of view and demonstrates their application to liquid, gas, solid, and polymer systems.

Drug-like Properties: Concepts, Structure Design and Methods

Author : Li Di
Publisher : Elsevier
ISBN 13 : 0080557619
Total Pages : 549 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Drug-like Properties: Concepts, Structure Design and Methods by : Li Di

Download or read book Drug-like Properties: Concepts, Structure Design and Methods written by Li Di and published by Elsevier. This book was released on 2010-07-26 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties. Serves as an essential working handbook aimed at scientists and students in medicinal chemistry Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies Discusses improvements in pharmacokinetics from a practical chemist's standpoint

Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development

Author :
Publisher : Elsevier
ISBN 13 : 0323884881
Total Pages : 434 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development by :

Download or read book Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development written by and published by Elsevier. This book was released on 2022-12-02 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development provides a valuable “go-to reference for many difficult-to-solve challenges using pertinent chromatographic theory, first-hand case studies, and examples provided from academic and industry experts. This text also enables professors teaching an analytical instrumental course to introduce and instruct students about one of the most sustainable and powerful separation methods currently available. While the text has broad applicability across industrial sectors, it focuses primarily on application in the pharmaceutical industry. The book is designed to allow readers to align current HPLC/UHPLC capabilities with SFC as an orthogonal tool for project specific methods in the pharmaceutical industry. It highlights where SFC falls on the spectrum of useful chromatographic tools for routine and challenging separative methods. Experienced HPLC users who are interested in developing knowledge in orthogonal separation techniques, as well as newcomers to the field of separation science, will find this text particularly useful. Chapters address where SFC may fit the analytical needs of the pharmaceutical industry and alert the readers as to where the technique will not fit. Readers will gain an understanding of how and where SFC may be applied and adapted more routinely across the pharmaceutical industry as a ‘green’ way of undertaking separation opportunities and challenges. Areas within the pharmaceutical industry include early drug discovery, process chemistry, and late stage development and manufacturing. Describes approaches to SFC column and mobile phase selection for method development for both analytical and preparative tasks Gives practical examples of how analytical SFC enables the monitoring of synthetic reactions including unstable intermediates, chiral and achiral polar reactants and products across small and large modalities Provides need-focused case studies for pharmaceutical analysts, process chemists, and contract chemistry facilities that can benefit from monitoring or purifying polar intermediates, mutagenic impurities, nitrosamines and other reaction by-products including excipients and metabolites

Application of Ionic Liquids in Drug Delivery

Author : Masahiro Goto
Publisher : Springer Nature
ISBN 13 : 9811643652
Total Pages : 246 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Application of Ionic Liquids in Drug Delivery by : Masahiro Goto

Download or read book Application of Ionic Liquids in Drug Delivery written by Masahiro Goto and published by Springer Nature. This book was released on 2021-08-27 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recent advances in the use of ionic liquids in medicine and pharmaceutics with particular emphasis on addressing critical pharmaceutical challenges, including the low solubility, polymorphism, and bioavailability of drugs. It also provides insights into the development of the biologically functionalized ionic liquids suitable for medical and pharmaceutical applications. Ionic liquids have been used as potential solvents or materials in the fields of pharmaceutical drug delivery and formulations because of their unique and tunable physicochemical and biological properties. Readers find explanations of the diverse approaches to the application of ionic liquids in drug solubility, active pharmaceutical ingredient (API) formulation, and drug delivery systems, such as topical, transdermal, and oral delivery, with particular emphasis on recent developments. Particular attention is given to the development of ionic liquid-assisted effective drug delivery techniques for sparingly soluble or insoluble drug molecules. This book also discusses the biological activities of ionic liquids for possible applications in drug formulation and drug delivery systems. Scientists in disciplines such as chemistry, biology, and pharmaceutics find this book instructive and informative for developing ionic liquid-based drug formulations or drug delivery systems.

Hansen Solubility Parameters

Author : Charles M. Hansen
Publisher : CRC Press
ISBN 13 : 1420006835
Total Pages : 546 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Hansen Solubility Parameters by : Charles M. Hansen

Download or read book Hansen Solubility Parameters written by Charles M. Hansen and published by CRC Press. This book was released on 2007-06-15 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hansen solubility parameters (HSPs) are used to predict molecular affinities, solubility, and solubility-related phenomena. Revised and updated throughout, Hansen Solubility Parameters: A User's Handbook, Second Edition features the three Hansen solubility parameters for over 1200 chemicals and correlations for over 400 materials including p

Industrial Applications of Nanocrystals

Author : Shadpour Mallakpour
Publisher : Elsevier
ISBN 13 : 0128242590
Total Pages : 518 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Industrial Applications of Nanocrystals by : Shadpour Mallakpour

Download or read book Industrial Applications of Nanocrystals written by Shadpour Mallakpour and published by Elsevier. This book was released on 2022-06-23 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approx.494 pages Approx.494 pages

Phosphoric Acids—Advances in Research and Application: 2012 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464991286
Total Pages : 949 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Phosphoric Acids—Advances in Research and Application: 2012 Edition by :

Download or read book Phosphoric Acids—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 949 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phosphoric Acids—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Phosphoric Acids. The editors have built Phosphoric Acids—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Phosphoric Acids in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Phosphoric Acids—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.