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Author : Phillip Michael Garfin
Publisher :
ISBN 13 :
Total Pages : 562 pages
Book Rating : 4.:/5 (592 download)
Download or read book Development of Midbrain Dopaminergic Neurons in the Chick Embryo written by Phillip Michael Garfin and published by . This book was released on 2004 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Expression and Functional Analysis of the Development of Mesencephalic Dopaminergic Neurons in the Chicken Embryo written by and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Within this thesis the development of dopaminergic neurons was investigated in the midbrain of the chicken embryo. Analysis of the expression of different marker genes of this cell population in the chicken embryo revealed phylogenetic differences compared to the mouse embryo. In addition, the role of the Wnt signaling pathway was analyzed with respect to the development of midbrain dopaminergic neurons in the chicken embryo. Expression of 9 out of 19 known Wnt genes was investigated and the functional role of Wnt9a was analyzed during embryonic development of the dopaminergic neurons in the midbrain. First, it could be shown that Wnt9a can ectopically induce the expression of different dopaminergic marker genes. Second, the genetic cascade was characterized which leads to the induction of these marker genes.
Author : Ruth Klafke
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (26 download)
Download or read book Expression and Functional Analysis of the Development of Mesencephalic Dopaminergic Neurons in the Chicken Embryo written by Ruth Klafke and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Umberto Di Porzio
Publisher : Landes Bioscience
ISBN 13 :
Total Pages : 210 pages
Book Rating : 4.E/5 ( download)
Download or read book Development of Dopaminergic Neurons written by Umberto Di Porzio and published by Landes Bioscience. This book was released on 1999 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Role of Dmrt5 During Development of Midbrain Dopaminergic Progenitors written by and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jeroen Pasterkamp
Publisher : Springer Science & Business Media
ISBN 13 : 1441903224
Total Pages : 143 pages
Book Rating : 4.4/5 (419 download)
Download or read book Development and Engineering of Dopamine Neurons written by Jeroen Pasterkamp and published by Springer Science & Business Media. This book was released on 2009-12-16 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theneurotransmitter dopamine has just celebrated its 50thbirthday. The discovery of dopamine as a neuronal entity in the late 1950s and the notion that it serves in neurotransmission has been a milestone in the field of neuroscience research. This milestone marked the beginning of an era that explored the brain as an integrated collection of neuronal systems that one could distinguish on basis of neurotransm- ter identities, and importantly, in which one started to be able to pinpoint the seat of brain disease. The mesodiencephalic dopaminergic (mdDA) system, previously designated as midbraindopaminergic system, has received much attention since its discovery. The initial identification of dopamine as a neurotransmitter in the central nervous system (CNS) and its relevance to psychiatric and neurological disorders have stimulated a plethora of neurochemical, pharmacological and genetic studies into the function of dopamine neurons and theirprojections. In the last decade, studies on gene expression and development have further increased the knowledge of this neuronal population and have unmasked a new level of complexity. The start of the molecular dissection of the mdDA system has been marked by the cloning and characterization ofNurrl and Pitx3. These transcription factors were shown to have a critical function during mdDA development. These initial studies have been followed by the identification of many other proteins, which have a crucial function in the creation of a dopamine neuron permissive region, induction of precursors, induction of terminaldifferent- tion and finally maintenance of the mdDA neuronal pool.
Author : Joanne M. Warrilow
Publisher :
ISBN 13 :
Total Pages : 269 pages
Book Rating : 4.:/5 (222 download)
Download or read book Development of Branchiomotor Neurons in the Chick Embryo written by Joanne M. Warrilow and published by . This book was released on 1997 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Holly Denise Keats
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (16 download)
Download or read book Gene Regulation in the Ventral Midbrain of the Developing Chick Embryo written by Holly Denise Keats and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Joanne Maria Warrilow
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (535 download)
Download or read book Branchiomotor Neuron Development in the Chick Embryo written by Joanne Maria Warrilow and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Concezio Di Rocco
Publisher : Springer
ISBN 13 : 9783319721675
Total Pages : 0 pages
Book Rating : 4.7/5 (216 download)
Download or read book Textbook of Pediatric Neurosurgery written by Concezio Di Rocco and published by Springer. This book was released on 2020-07-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book documents the state of the art in pediatric neurosurgery with the intention of providing a comprehensive guide to the management of the full range of pediatric neurosurgical disorders that will aid in the delivery of optimal care. Detailed practical instruction, taking into account recent advances, is provided on the neurosurgical treatment of congenital brain malformations, cerebrovascular diseases, head injuries and spinal trauma, infections, functional disorders, congenital and developmental spinal disorders, and brain and spinal tumors. Pearls and pitfalls are highlighted, and attention drawn to the most useful tips and tricks. Information is also included on relevant related topics, including the principles of neuroimaging, the physiological responses of newborns, infants, and children to neurosurgical trauma, preoperative evaluation, anesthesiology and intensive care, and other forms of therapy. The authors are renowned experts in the field, and the text is supported by a wealth of high-quality images. Handbook of Pediatric Neurosurgery will be of value for neurosurgeons of all levels of experience, as well as for pediatricians, neuroradiologists, neuropathologists, and neuro-oncologists.
Author :
Publisher :
ISBN 13 : 9789492801524
Total Pages : 222 pages
Book Rating : 4.8/5 (15 download)
Download or read book Wiring Up Diversity written by and published by . This book was released on 2018 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Hans J. ten Donkelaar
Publisher : Springer Science & Business Media
ISBN 13 : 3540346597
Total Pages : 544 pages
Book Rating : 4.5/5 (43 download)
Download or read book Clinical Neuroembryology written by Hans J. ten Donkelaar and published by Springer Science & Business Media. This book was released on 2006-09-07 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in developmental neurobiology and advances in (neuro) genetics have been spectacular. The high resolution of modern imaging techniques applicable to developmental disorders of the human brain and spinal cord have created a novel insight into the developmental history of the central nervous system (CNS). This book provides a comprehensive overview of the development of the human CNS in the context of its many developmental disorders. It provides a unique combination of data from human embryology, animal research and developmental neuropathology, and there are more than 400 figures in over a hundred separate illustrations.
Author : Giuseppe di Giovanni
Publisher : Springer Science & Business Media
ISBN 13 : 3211926607
Total Pages : 357 pages
Book Rating : 4.2/5 (119 download)
Download or read book Birth, Life and Death of Dopaminergic Neurons in the Substantia Nigra written by Giuseppe di Giovanni and published by Springer Science & Business Media. This book was released on 2009-09-02 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and pathology of the substantia nigra pars compacta (SNc) dopaminergic neurons. The single chapters, written by top scientists in their fields, explore the life cycle of dopaminergic neurons from their birth to death, the cause of Parkinson's disease, the second most common and disabling condition in the elderly population. Nevertheless, the intracellular cascade of events leading to dopamine cell death is still unknown and, consequently, treatment is symptomatic rather than preventive. The mechanisms by which alterations cause neuronal death, new therapeutic approaches and the latest evidence of a possible de novo neurogenesis in the SNc are reviewed and singled out in different chapters. This book bridges basic science and clinical practice and will prepare the reader for the next few years, which will surely be eventful in terms of the progress of dopamine research.
Author : Mahendra S. Rao
Publisher : Springer Science & Business Media
ISBN 13 : 1461438012
Total Pages : 370 pages
Book Rating : 4.4/5 (614 download)
Download or read book Neural Development and Stem Cells written by Mahendra S. Rao and published by Springer Science & Business Media. This book was released on 2012-06-05 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This expanded and updated edition reflects the enormous increase in our knowledge of the development of the nervous system and the use of neural stem cells in clinical applications. Integrating new information about the use of development of neural stem cells for clinical applications, Drs. Rao, Carpenter and Vemuri have added additional chapters on neural transplantation and development of neural stem cells using reprogramming technologies. A new chapter on cancer in nervous system delineates how the fundamental biology of neural stem cells informs our understanding of cancer and tumor formation in the nervous system. Special attention is paid to the derivation of neural cells from embryonic stem cells and induced pluripotent stem cells. Authoritative and up-to-date, Neural Development and Stem Cells, 3rd Edition provides neuroscientists with a handy guide to stem cells in the nervous system, tracing with great clarity the development of stem cells from differentiation to neurons, astrocytes, and oligodendrocytes.
Author : D. G. Wilkinson
Publisher : Oxford University Press, USA
ISBN 13 : 9780199636587
Total Pages : 224 pages
Book Rating : 4.6/5 (365 download)
Download or read book In Situ Hybridization written by D. G. Wilkinson and published by Oxford University Press, USA. This book was released on 1998 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: In situ hybridization is used to reveal the location of specific nucleic acids sequences on chromosomes or in tissues. Visualization of the location of genes on chromosomes or of specific mRNAs or viruses in tissues is crucial for understanding the organization, regulation, and function of genes. It is a therefore a core technique in all areas of biomedical research. In Situ Hybridization: A Practical Approach 2/e is the second edition of one of the most successful Practical Approach books, published in 1992. Since the first edition was published, a number of important technical advances have been made. The new edition has been thoroughly updated to contain protocols detailing the major techniques of in situ hybridization currently in use: in situ hybridization to mRNA with oligonucleotide and RNA probes (radiolabelled and hapten labelled); analysis using light and electron microscopes; whole mount in situ hybridization; double detection of RNAs, and RNA plus protein; and fluorescent in situ hybridization to detect chromosomal sequences. The protocols are complemented by advice on strategies for successful results, descriptions of the theoretical basis of in situ hybridization and important new developments in gene expression databases. The procedures described are widely applicable to many systems. The use of in situ hybridization in PCR is covered in a separate volume: Herrington and O'Leary (Eds) PCR 3 - PCR in situ hybridization: A Practical Approach (OUP, 1997). All the authors have extensive practical experience of establishing reliable techniques of in situ hybridization. This book will be useful to all researchers at all levels who use in situ hybridization.
Author :
Publisher : Academic Press
ISBN 13 : 0123973481
Total Pages : 993 pages
Book Rating : 4.1/5 (239 download)
Download or read book Patterning and Cell Type Specification in the Developing CNS and PNS written by and published by Academic Press. This book was released on 2013-05-06 with total page 993 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 1 sections include coverage of mechanisms which: control regional specification, regulate proliferation of neuronal progenitors and control differentiation and survival of specific neuronal subtypes, and controlling development of non-neural cells
Author : S.R.W. Stott
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128062282
Total Pages : 55 pages
Book Rating : 4.1/5 (28 download)
Download or read book Comprehensive Developmental Neuroscience: Patterning and Cell Type Specification in the Developing CNS and PNS written by S.R.W. Stott and published by Elsevier Inc. Chapters. This book was released on 2013-05-06 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt:
