Development Of A Modular Software System For Modeling And Analyzing Biological Pathways

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Computational Systems Biology

Author : Andres Kriete
Publisher : Academic Press
ISBN 13 : 0124059384
Total Pages : 549 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Computational Systems Biology by : Andres Kriete

Download or read book Computational Systems Biology written by Andres Kriete and published by Academic Press. This book was released on 2013-11-26 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling. - Logical information flow aids understanding of basic building blocks of life through disease phenotypes - Evolved principles gives insight into underlying organizational principles of biological organizations, and systems processes, governing functions such as adaptation or response patterns - Coverage of technical tools and systems helps researchers to understand and resolve specific systems biology problems using advanced computation - Multi-scale modeling on disparate scales aids researchers understanding of dependencies and constraints of spatio-temporal relationships fundamental to biological organization and function.

Bioinformatics and Systems Biology

Author : Frederick Marcus
Publisher : Springer Science & Business Media
ISBN 13 : 3540783539
Total Pages : 296 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Bioinformatics and Systems Biology by : Frederick Marcus

Download or read book Bioinformatics and Systems Biology written by Frederick Marcus and published by Springer Science & Business Media. This book was released on 2008-07-22 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collaborative research in bioinformatics and systems biology is a key element of modern biology and health research. This book highlights and provides access to many of the methods, environments, results and resources involved, including integral laboratory data generation and experimentation and clinical activities. Collaborative projects embody a research paradigm that connects many of the top scientists, institutions, their resources and research worldwide, resulting in first-class contributions to bioinformatics and systems biology. Central themes include describing processes and results in collaborative research projects using computational biology and providing a guide for researchers to access them. The book is also a practical guide on how science is managed. It shows how collaborative researchers are putting results together in a way accessible to the entire biomedical community.

Bioinformatics

Author : Dev Bukhsh Singh
Publisher : Academic Press
ISBN 13 : 0323900054
Total Pages : 512 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Bioinformatics by : Dev Bukhsh Singh

Download or read book Bioinformatics written by Dev Bukhsh Singh and published by Academic Press. This book was released on 2021-10-21 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics: Methods and Applications provides a thorough and detailed description of principles, methods, and applications of bioinformatics in different areas of life sciences. It presents a compendium of many important topics of current advanced research and basic principles/approaches easily applicable to diverse research settings. The content encompasses topics such as biological databases, sequence analysis, genome assembly, RNA sequence data analysis, drug design, and structural and functional analysis of proteins. In addition, it discusses computational approaches for vaccine design, systems biology and big data analysis, and machine learning in bioinformatics.It is a valuable source for bioinformaticians, computer biologists, and members of biomedical field who needs to learn bioinformatics approaches to apply to their research and lab activities. - Covers basic and more advanced developments of bioinformatics with a diverse and interdisciplinary approach to fulfill the needs of readers from different backgrounds - Explains in a practical way how to decode complex biological problems using computational approaches and resources - Brings case studies, real-world examples and several protocols to guide the readers with a problem-solving approach

Morphological Integration

Author : Everett C. Olson
Publisher : University of Chicago Press
ISBN 13 : 9780226629056
Total Pages : 380 pages
Book Rating : 4.6/5 (29 download)

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Book Synopsis Morphological Integration by : Everett C. Olson

Download or read book Morphological Integration written by Everett C. Olson and published by University of Chicago Press. This book was released on 1999-10 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite recent advances in genetics, development, anatomy, systematics, and morphometrics, the synthesis of ideas and research agenda put forth in the classic Morphological Integration remains remarkably fresh, timely, and relevant. Pioneers in reexamining morphology, Everett Olson and Robert Miller were among the first to explore the concept of the integrated organism in both living and extinct populations. In a new foreword and afterword, biologists Barry Chernoff and Paul Magwene summarize the landmark achievements made by Olson and Miller and bring matters discussed in the book up to date, suggest new methods, and accentuate the importance of continued research in morphological integration. Everett C. Olson was a professor at the University of Chicago and at the University of California, Los Angeles. He was a former president of the Society of Vertebrate Paleontology. Robert L. Miller was associate professor of geology at the University of Chicago, associate scientist in marine geology at the Woods Hole Oceanographic Institution, and a member of the board of editors of the Journal of Geology.

Encyclopedia of Chemical Processing (Online)

Author : Sunggyu Lee
Publisher : CRC Press
ISBN 13 : 1351237683
Total Pages : 3338 pages
Book Rating : 4.3/5 (512 download)

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Book Synopsis Encyclopedia of Chemical Processing (Online) by : Sunggyu Lee

Download or read book Encyclopedia of Chemical Processing (Online) written by Sunggyu Lee and published by CRC Press. This book was released on 2005-11-01 with total page 3338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition Encyclopedia supplies nearly 350 gold standard articles on the methods, practices, products, and standards influencing the chemical industries. It offers expertly written articles on technologies at the forefront of the field to maximize and enhance the research and production phases of current and emerging chemical manufacturing practices and techniques. This collecting of information is of vital interest to chemical, polymer, electrical, mechanical, and civil engineers, as well as chemists and chemical researchers. A complete reconceptualization of the classic reference series the Encyclopedia of Chemical Processing and Design, whose first volume published in 1976, this resource offers extensive A-Z treatment of the subject in five simultaneously published volumes, with comprehensive indexing of all five volumes in the back matter of each tome. It includes material on the design of key unit operations involved with chemical processes; the design, unit operation, and integration of reactors and separation systems; process system peripherals such as pumps, valves, and controllers; analytical techniques and equipment; and pilot plant design and scale-up criteria. This reference contains well-researched sections on automation, equipment, design and simulation, reliability and maintenance, separations technologies, and energy and environmental issues. Authoritative contributions cover chemical processing equipment, engineered systems, and laboratory apparatus currently utilized in the field. It also presents expert overviews on key engineering science topics in property predictions, measurements and analysis, novel materials and devices, and emerging chemical fields. ALSO AVAILABLE ONLINE This Taylor & Francis encyclopedia is also available through online subscription, offering a variety of extra benefits for both researchers, students, and librarians, including: Citation tracking and alerts Active reference linking Saved searches and marked lists HTML and PDF format options Contact Taylor and Francis for more information or to inquire about subscription options and print/online combination packages. US: (Tel) 1.888.318.2367; (E-mail) [email protected] International: (Tel) +44 (0) 20 7017 6062; (E-mail) [email protected]

Encyclopedia of Chemical Processing

Author : Sunggyu Lee
Publisher : Taylor & Francis US
ISBN 13 : 9780824755003
Total Pages : 768 pages
Book Rating : 4.7/5 (55 download)

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Book Synopsis Encyclopedia of Chemical Processing by : Sunggyu Lee

Download or read book Encyclopedia of Chemical Processing written by Sunggyu Lee and published by Taylor & Francis US. This book was released on 2006 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supplying nearly 350 expertly-written articles on technologies that can maximize and enhance the research and production phases of current and emerging chemical manufacturing practices and techniques, this second edition provides gold standard articles on the methods, practices, products, and standards recently influencing the chemical industries. New material includes: design of key unit operations involved with chemical processes; design, unit operation, and integration of reactors and separation systems; process system peripherals such as pumps, valves, and controllers; analytical techniques and equipment; current industry practices; and pilot plant design and scale-up criteria.

DOE Genomics

Author :
Publisher :
ISBN 13 :
Total Pages : 320 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis DOE Genomics by :

Download or read book DOE Genomics written by and published by . This book was released on 2005 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Systems Biology

Author : Edda Klipp
Publisher : John Wiley & Sons
ISBN 13 : 3527644997
Total Pages : 593 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Systems Biology by : Edda Klipp

Download or read book Systems Biology written by Edda Klipp and published by John Wiley & Sons. This book was released on 2013-06-20 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: This advanced textbook is tailored to the needs of introductory course in Systems Biology. It has a compagnion website (www.wiley-vch.de/home/systemsbiology)with solutions to questions in the book and several additional extensive working models. The book is related to the very successful previous title 'Systems Biology in Practice' and has incorporated the feedback and suggestions from many lecturers worldwide. The book addresses biologists as well as engineers and computer scientists. The interdisciplinary team of acclaimed authors worked closely together to ensure a comprehensive coverage with no overlaps in a homogenous and compelling style.

Bioinformatics

Author : Ralf Hofestädt
Publisher : Springer Science & Business Media
ISBN 13 : 9783540633709
Total Pages : 244 pages
Book Rating : 4.6/5 (337 download)

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Book Synopsis Bioinformatics by : Ralf Hofestädt

Download or read book Bioinformatics written by Ralf Hofestädt and published by Springer Science & Business Media. This book was released on 1997-08-06 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the strictly refereed post-workshop proceedings of the German Conference on Bioinformatics, GCB'96, held in Leipzig, Germany, in September/October 1996. The volume presents 18 revised full papers together with three invited papers; these contributions were selected after a second round of reviewing from the 91 conference presentations. The book addresses current issues in computational biology and biologically inspired computing. The papers are organized in sections on biological and metabolic pathways, sequence analysis, molecular modeling, visualization, and formal languages, and DNA.

Metabolic Pathway Design

Author : Pablo Carbonell
Publisher : Springer Nature
ISBN 13 : 3030298655
Total Pages : 170 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Metabolic Pathway Design by : Pablo Carbonell

Download or read book Metabolic Pathway Design written by Pablo Carbonell and published by Springer Nature. This book was released on 2019-11-05 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook presents solid tools for in silico engineering biology, offering students a step-by-step guide to mastering the smart design of metabolic pathways. The first part explains the Design-Build-Test-Learn-cycle engineering approach to biology, discussing the basic tools to model biological and chemistry-based systems. Using these basic tools, the second part focuses on various computational protocols for metabolic pathway design, from enzyme selection to pathway discovery and enumeration. In the context of industrial biotechnology, the final part helps readers understand the challenges of scaling up and optimisation. By working with the free programming language Scientific Python, this book provides easily accessible tools for studying and learning the principles of modern in silico metabolic pathway design. Intended for advanced undergraduates and master’s students in biotechnology, biomedical engineering, bioinformatics and systems biology students, the introductory sections make it also useful for beginners wanting to learn the basics of scientific coding and find real-world, hands-on examples.

Handbook of Research Methods in Complexity Science

Author : Eve Mitleton-Kelly
Publisher : Edward Elgar Publishing
ISBN 13 : 1785364421
Total Pages : 642 pages
Book Rating : 4.7/5 (853 download)

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Book Synopsis Handbook of Research Methods in Complexity Science by : Eve Mitleton-Kelly

Download or read book Handbook of Research Methods in Complexity Science written by Eve Mitleton-Kelly and published by Edward Elgar Publishing. This book was released on 2018-01-26 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive Handbook is aimed at both academic researchers and practitioners in the field of complexity science. The book’s 26 chapters, specially written by leading experts, provide in-depth coverage of research methods based on the sciences of complexity. The research methods presented are illustratively applied to practical cases and are readily accessible to researchers and decision makers alike.

Computational Systems Neurobiology

Author : N. Le Novère
Publisher : Springer Science & Business Media
ISBN 13 : 9400738587
Total Pages : 569 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Computational Systems Neurobiology by : N. Le Novère

Download or read book Computational Systems Neurobiology written by N. Le Novère and published by Springer Science & Business Media. This book was released on 2012-07-20 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational neurosciences and systems biology are among the main domains of life science research where mathematical modeling made a difference. This book introduces the many different types of computational studies one can develop to study neuronal systems. It is aimed at undergraduate students starting their research in computational neurobiology or more senior researchers who would like, or need, to move towards computational approaches. Based on their specific project, the readers would then move to one of the more specialized excellent textbooks available in the field. The first part of the book deals with molecular systems biology. Functional genomics is introduced through examples of transcriptomics and proteomics studies of neurobiological interest. Quantitative modelling of biochemical systems is presented in homogeneous compartments and using spatial descriptions. A second part deals with the various approaches to model single neuron physiology, and naturally moves to neuronal networks. A division is focused on the development of neurons and neuronal systems and the book closes on a series of methodological chapters. From the molecules to the organ, thinking at the level of systems is transforming biology and its impact on society. This book will help the reader to hop on the train directly in the tank engine.

Encyclopedia of Cell Biology

Author :
Publisher : Academic Press
ISBN 13 : 0123947960
Total Pages : 2972 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Encyclopedia of Cell Biology by :

Download or read book Encyclopedia of Cell Biology written by and published by Academic Press. This book was released on 2015-08-07 with total page 2972 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Cell Biology, Four Volume Set offers a broad overview of cell biology, offering reputable, foundational content for researchers and students across the biological and medical sciences. This important work includes 285 articles from domain experts covering every aspect of cell biology, with fully annotated figures, abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, the Encyclopedia of Cell Biology provides a fully cross-referenced, one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences. Fully annotated color images and videos for full comprehension of concepts, with layered content for readers from different levels of experience Includes information on cytokinesis, cell biology, cell mechanics, cytoskeleton dynamics, stem cells, prokaryotic cell biology, RNA biology, aging, cell growth, cell Injury, and more In-depth linking to Academic Press/Elsevier content and additional links to outside websites and resources for further reading A one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences

Verification, Model Checking, and Abstract Interpretation

Author : Ranjit Jhala
Publisher : Springer Science & Business Media
ISBN 13 : 3642182747
Total Pages : 430 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Verification, Model Checking, and Abstract Interpretation by : Ranjit Jhala

Download or read book Verification, Model Checking, and Abstract Interpretation written by Ranjit Jhala and published by Springer Science & Business Media. This book was released on 2011-01-11 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 12th International Conference on Verification, Model Checking, and Abstract Interpretation, VMCAI 2011, held in Austin, TX, USA, in January 2011, co-located with the Symposium on Principles of Programming Languages, POPL 2011. The 24 revised full papers presented together with 4 invited talks were carefully reviewed and selected from 71 initial submissions. The papers showcases state-of-the-art research in areas such as verification, model checking, abstract interpretation and address any programming paradigm, including concurrent, constraint, functional, imperative, logic and object-oriented programming. Further topics covered are static analysis, deductive methods, program certification, debugging techniques, abstract domains, type systems, and optimization.

Engineering Synthetic Metabolons: From Metabolic Modelling to Rational Design of Biosynthetic Devices

Author : Lars M. Voll
Publisher : Frontiers Media SA
ISBN 13 : 2889199215
Total Pages : 132 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Engineering Synthetic Metabolons: From Metabolic Modelling to Rational Design of Biosynthetic Devices by : Lars M. Voll

Download or read book Engineering Synthetic Metabolons: From Metabolic Modelling to Rational Design of Biosynthetic Devices written by Lars M. Voll and published by Frontiers Media SA. This book was released on 2016-07-19 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discipline of Synthetic Biology has recently emerged at the interface of biology and engineering. The definition of Synthetic Biology has been dynamic over time ever since, which exemplifies that the field is rapidly moving and comprises a broad range of research areas. In the frame of this Research Topic, we focus on Synthetic Biology approaches that aim at rearranging biological parts/ entities in order to generate novel biochemical functions with inherent metabolic activity. This Research Topic encompasses Pathway Engineering in living systems as well as the in vitro assembly of biomolecules into nano- and microscale bioreactors. Both, the engineering of metabolic pathways in vivo, as well as the conceptualization of bioreactors in vitro, require rational design of assembled synthetic pathways and depend on careful selection of individual biological functions and their optimization. Mathematical modelling has proven to be a powerful tool in predicting metabolic flux in living and artificial systems, although modelling approaches have to cope with a limitation in experimentally verified, reliable input variables. This Research Topic puts special emphasis on the vital role of modelling approaches for Synthetic Biology, i.e. the predictive power of mathematical simulations for (i) the manipulation of existing pathways and (ii) the establishment of novel pathways in vivo as well as (iii) the translation of model predictions into the design of synthetic assemblies.

Functional Plant Genomics

Author : J F Morot-Gaudry
Publisher : CRC Press
ISBN 13 : 1439843171
Total Pages : 714 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Functional Plant Genomics by : J F Morot-Gaudry

Download or read book Functional Plant Genomics written by J F Morot-Gaudry and published by CRC Press. This book was released on 2013-11-13 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: The openings offered by functional genomics reconciles organism biology and molecular biology, in order to define an integrative biology that should allow new insights about how a phenotype is built up from a genotype in interaction with its environment. This book covers a wide area of concepts and methods in genomics. This range from international

Foundations of Theoretical Approaches in Systems Biology

Author : Alberto Marin-Sanguino
Publisher : Frontiers Media SA
ISBN 13 : 2889456838
Total Pages : 216 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Foundations of Theoretical Approaches in Systems Biology by : Alberto Marin-Sanguino

Download or read book Foundations of Theoretical Approaches in Systems Biology written by Alberto Marin-Sanguino and published by Frontiers Media SA. This book was released on 2019-01-11 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: If biology in the 20th century was characterized by an explosion of new technologies and experimental methods, that of the 21st has seen an equally exuberant proliferation of mathematical and computational methods that attempt to systematize and explain the abundance of available data. As we live through the consolidation of a new paradigm where experimental data goes hand in hand with computational analysis, we contemplate the challenge of fusing these two aspects of the new biology into a consistent theoretical framework. Whether systems biology will survive as a field or be washed away by the tides of future fads will ultimately depend on its success to achieve this type of synthesis. The famous quote attributed to Kurt Lewin comes to mind: "there is nothing more practical than a good theory". This book presents a wide assortment of articles on systems biology in an attempt to capture the variety of current methods in systems biology and show how they can help to find answers to the challenges of modern biology.