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Development And Processing Of Leu Targets For 99mo Production
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Book Synopsis Medical Isotope Production Without Highly Enriched Uranium by : National Research Council
Download or read book Medical Isotope Production Without Highly Enriched Uranium written by National Research Council and published by National Academies Press. This book was released on 2009-06-27 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the product of a congressionally mandated study to examine the feasibility of eliminating the use of highly enriched uranium (HEU2) in reactor fuel, reactor targets, and medical isotope production facilities. The book focuses primarily on the use of HEU for the production of the medical isotope molybdenum-99 (Mo-99), whose decay product, technetium-99m3 (Tc-99m), is used in the majority of medical diagnostic imaging procedures in the United States, and secondarily on the use of HEU for research and test reactor fuel. The supply of Mo-99 in the U.S. is likely to be unreliable until newer production sources come online. The reliability of the current supply system is an important medical isotope concern; this book concludes that achieving a cost difference of less than 10 percent in facilities that will need to convert from HEU- to LEU-based Mo-99 production is much less important than is reliability of supply.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309445310 Total Pages :264 pages Book Rating :4.3/5 (94 download)
Book Synopsis Molybdenum-99 for Medical Imaging by : National Academies of Sciences, Engineering, and Medicine
Download or read book Molybdenum-99 for Medical Imaging written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-11-28 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: The decay product of the medical isotope molybdenum-99 (Mo-99), technetium-99m (Tc-99m), and associated medical isotopes iodine-131 (I-131) and xenon-133 (Xe-133) are used worldwide for medical diagnostic imaging or therapy. The United States consumes about half of the world's supply of Mo-99, but there has been no domestic (i.e., U.S.-based) production of this isotope since the late 1980s. The United States imports Mo-99 for domestic use from Australia, Canada, Europe, and South Africa. Mo-99 and Tc-99m cannot be stockpiled for use because of their short half-lives. Consequently, they must be routinely produced and delivered to medical imaging centers. Almost all Mo-99 for medical use is produced by irradiating highly enriched uranium (HEU) targets in research reactors, several of which are over 50 years old and are approaching the end of their operating lives. Unanticipated and extended shutdowns of some of these old reactors have resulted in severe Mo-99 supply shortages in the United States and other countries. Some of these shortages have disrupted the delivery of medical care. Molybdenum-99 for Medical Imaging examines the production and utilization of Mo-99 and associated medical isotopes, and provides recommendations for medical use.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :030946627X Total Pages :87 pages Book Rating :4.3/5 (94 download)
Book Synopsis Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets by : National Academies of Sciences, Engineering, and Medicine
Download or read book Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-03-12 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: Participants of the July 17-18, 2017, symposium titled Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets examined current trends in molybdenum-99 production, prospects for new global supplies, and technical, economic, regulatory, and other considerations for supplying molybdenum-99 to global markets. This publication summarizes the presentations and discussions from the symposium.
Download or read book The Supply of Medical Isotopes written by and published by . This book was released on 2019 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report explores the main reasons behind the unreliable supply of Technetium-99m (Tc-99m) in health-care systems and policy options to address the issue. Tc-99m is used in 85% of nuclear medicine diagnostic scans performed worldwide – around 30 million patient examinations every year. These scans allow diagnoses of diseases in many parts of the human body, including the skeleton, heart and circulatory system, and the brain. Medical isotopes are subject to radioactive decay and have to be delivered just-in-time through a complex supply chain. However, ageing production facilities and a lack of investment have made the supply of Tc-99m unreliable. This report analyses the use and substitutability of Tc-99m in health care, health-care provider payment mechanisms for scans, and the structure of the supply chain. It concludes that the main reasons for unreliable supply are that production is not economically viable and that the structure of the supply chain prevents producers from charging prices that reflect the full costs of production and supply.
Book Synopsis Nuclear Energy Basic Principles by : International Atomic Energy Agency
Download or read book Nuclear Energy Basic Principles written by International Atomic Energy Agency and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes the rationale and vision for the peaceful use of nuclear energy. The publication identifies the basic principles that nuclear energy systems must satisfy to fulfil their promise of meeting growing global energy demands.
Author :Shankar Vallabhajosula Publisher :Springer Science & Business Media ISBN 13 :3540767355 Total Pages :379 pages Book Rating :4.5/5 (47 download)
Book Synopsis Molecular Imaging by : Shankar Vallabhajosula
Download or read book Molecular Imaging written by Shankar Vallabhajosula and published by Springer Science & Business Media. This book was released on 2009-07-13 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309379210 Total Pages :205 pages Book Rating :4.3/5 (93 download)
Book Synopsis Reducing the Use of Highly Enriched Uranium in Civilian Research Reactors by : National Academies of Sciences, Engineering, and Medicine
Download or read book Reducing the Use of Highly Enriched Uranium in Civilian Research Reactors written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-02-12 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: The continued presence of highly enriched uranium (HEU) in civilian installations such as research reactors poses a threat to national and international security. Minimization, and ultimately elimination, of HEU in civilian research reactors worldwide has been a goal of U.S. policy and programs since 1978. Today, 74 civilian research reactors around the world, including 8 in the United States, use or are planning to use HEU fuel. Since the last National Academies of Sciences, Engineering, and Medicine report on this topic in 2009, 28 reactors have been either shut down or converted from HEU to low enriched uranium fuel. Despite this progress, the large number of remaining HEU-fueled reactors demonstrates that an HEU minimization program continues to be needed on a worldwide scale. Reducing the Use of Highly Enriched Uranium in Civilian Research Reactors assesses the status of and progress toward eliminating the worldwide use of HEU fuel in civilian research and test reactors.
Book Synopsis Analysis of Cancer Risks in Populations Near Nuclear Facilities by : National Research Council
Download or read book Analysis of Cancer Risks in Populations Near Nuclear Facilities written by National Research Council and published by National Academies Press. This book was released on 2012-06-29 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.
Book Synopsis Molten-Salt Reactor Program Semiannual Progress Report for Period Ending ... by : Oak Ridge National Laboratory
Download or read book Molten-Salt Reactor Program Semiannual Progress Report for Period Ending ... written by Oak Ridge National Laboratory and published by . This book was released on 1965-02 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Reactor Physics Constants by : Reactor Physics Constants Center (U.S.)
Download or read book Reactor Physics Constants written by Reactor Physics Constants Center (U.S.) and published by . This book was released on 1963 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mathematical Modeling in Experimental Nutrition by : Andrew J. Clifford
Download or read book Mathematical Modeling in Experimental Nutrition written by Andrew J. Clifford and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrients have been recognized as essential for maximum growth, successful reproduction, and infection prevention since the 1940s; since that time, the lion's share of nutrient research has focused on defining their role in these processes. Around 1990, however, a major shift began in the way that researchers viewed some nutrients particularly the vitamins. This shift was motivated by the discovery that modest declines in vitamin nutritional status are associated with an increased risk of ill-health and disease (such as neural tube defects, heart disease, and cancer), especially in those populations or individuals who are genetically predisposed. In an effort to expand upon this new understanding of nutrient action, nutritionists are increasingly turning their focus to the mathematical modeling of nutrient kinetic data. The availability of suitably-tagged (isotope) nutrients (such as B-carotene, vitamin A, folate, among others), sensitive analytical methods to trace them in humans (mass spectrometry and accelerator mass spectrometry), and powerful software (capable of solving and manipulating differential equations efficiently and accurately), has allowed researchers to construct mathematical models aimed at characterizing the dynamic and kinetic behavior of key nutrients in vivo in humans at an unparalleled level of detail.
Book Synopsis Production of Long Lived Parent Radionuclides for Generators, 68Ge, 82Sr, 90Sr and 188W. by : International Atomic Energy Agency
Download or read book Production of Long Lived Parent Radionuclides for Generators, 68Ge, 82Sr, 90Sr and 188W. written by International Atomic Energy Agency and published by United Nations Publications. This book was released on 2010 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides information on the production and processing of four important long lived parent radionuclides, 68Ge, 82Sr, 90Sr and 188W, used for the preparation of generators for nuclear medicine applications such as positron emission tomography and therapy. It includes descriptions of the production routes for and process chemistry of the selected parent radionuclides, including relevant separation approaches. Information on use of the generator system and on physical and chemical characteristics is also provided.
Book Synopsis Radiotracer Generators for Industrial Applications by : International Atomic Energy Agency
Download or read book Radiotracer Generators for Industrial Applications written by International Atomic Energy Agency and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a unique source of information pertaining to the development of radiotracer generators and their use in troubleshooting and optimizing industrial processes. The publication describes the results of research undertaken on the characterization of 68Ge/68Ga, 137Cs/137mBa, 99Mo/99mTc and 113Sn/113mIn radiotracer generators.
Author :Charles D. Ferguson Publisher :Monterey Institute of Intern Oliferation Studies ISBN 13 : Total Pages :90 pages Book Rating :4.:/5 (318 download)
Book Synopsis Commercial Radioactive Sources by : Charles D. Ferguson
Download or read book Commercial Radioactive Sources written by Charles D. Ferguson and published by Monterey Institute of Intern Oliferation Studies. This book was released on 2003 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :International Atomic Energy Agency Publisher :International Atomic Energy Agency ISBN 13 :9789201450104 Total Pages :108 pages Book Rating :4.4/5 (51 download)
Book Synopsis Applications of Research Reactors by : International Atomic Energy Agency
Download or read book Applications of Research Reactors written by International Atomic Energy Agency and published by International Atomic Energy Agency. This book was released on 2014 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is a comprehensive study that reviews the current situation in a great number of applications of research reactors. It revises the contents of IAEA TECDOC-1234, The Applications of Research Reactors, giving detailed updates on each field of research reactor uses worldwide. Reactors of all sizes and capabilities can benefit from the sharing of current practices and research enabled via this updated version, which describes the requirements for practicing methods as diverse as neutron activation analysis, education and training, neutron scattering and neutron imaging, silicon doping and radioisotope production, material/fuel irradiation and testing, and some others. Many underutilised research reactors can learn how to diversify their technical capabilities, staff and potential commercial partners and users seeking research reactor services and products. The content of the publication has also been strengthened in terms of current issues facing the vast majority of research reactors by including sections describing user and customer relations as well as strategic planning considerations.
Book Synopsis Revisiting South Africa's Nuclear Weapons Program by : David Albright
Download or read book Revisiting South Africa's Nuclear Weapons Program written by David Albright and published by Createspace Independent Publishing Platform. This book was released on 2016-09-24 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1989, South Africa made the momentous decision to abandon its nuclear weapons, making it the first and still the only country that has produced nuclear weapons and given them up. Over thirty years, the apartheid regime had created a remarkably sophisticated capability to build nuclear weapons-both the nuclear warhead and advanced military systems to deliver them. The program was born in secret and remained so until its end. The government initially sought to dismantle it in secret. It hoped to avoid any negative international consequences of possessing nuclear weapons. The apartheid government's strategy did not work, because too many intelligence agencies knew about South Africa's nuclear weapons. Faced with intense pressure, South Africa's President F.W. de Klerk reversed course and adopted a policy of transparency in 1993. However, he decided to hide many of its aspects. Nonetheless, most of the remaining secrets emerged over the ensuing 25 years. Revisiting South Africa's Nuclear Weapons Program draws on previously secret information to provide the first comprehensive, technically-oriented look at South Africa's nuclear weapons program; how it grew, evolved, and ended. It also finds lessons for today's nuclear proliferation cases.
Book Synopsis History, Development and Future of TRIGA Research Reactors by :
Download or read book History, Development and Future of TRIGA Research Reactors written by and published by . This book was released on 2016 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt:
