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Development And Fabrication Of Ion Sensitive Field Effect Transistor Isfet For Ph Detection Dna Immobilization And Hybridization
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Book Synopsis Development and Fabrication of Ion-sensitive Field Effect Transistor (ISFET) for PH Detection, DNA Immobilization and Hybridization by :
Download or read book Development and Fabrication of Ion-sensitive Field Effect Transistor (ISFET) for PH Detection, DNA Immobilization and Hybridization written by and published by . This book was released on 2013 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis describes the design, fabrication and characterization of ISFET for pH detection, DNA immobilization and hybridization.
Book Synopsis Ion-sensitive Field Effect Transistor (ISFET) for MEMS Multisensory Chips at RIT by : Murat Baylav
Download or read book Ion-sensitive Field Effect Transistor (ISFET) for MEMS Multisensory Chips at RIT written by Murat Baylav and published by . This book was released on 2010 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This study involves the design and fabrication of an Ion-Sensitive Field Effect Transistor (ISFET), which is aimed to be incorporated into the multisensory chips fabricated at RIT. ISFETs are used for various purposes in biomedical, medicine, and chemical applications and have advantages such as small size, low power consumption, robustness, and fast response time, over the ion-selective electrode (ISE) counterparts. The capability of fabricating ISFETs in a standard CMOS process let them to be used in sensor systems together with the dedicated signal processing circuitry which in turn makes portable applications possible. The ISFET fabricated in this study have a SiO2 gate oxide and on top of that a Si3N4 layer. The latter layer, in addition to passivating the device, serves as a pH sensitive membrane. The overall process has 5 mask levels and the electrical tests, which were performed using buffer solutions with varying pH values, indicated that the transistor can be employed to measure the pH of solutions. ISFETs were also tested against environmental conditions such as temperature, long term exposure to various pH-valued solutions and it is found out that the FETs are quite robust in terms of temperature stability and long term drift. In addition to their pH sensing properties, these devices were also taken one step ahead to sense chloride ion (Cl-) concentration via preparing a Cl--sensitive membrane stacked on top of the Si3N4 layer. Electrical tests, which were performed in solutions with various Cl- concentrations, showed that the modified ISFETs are also Cl- sensitive."--Abstract.
Book Synopsis Ion Sensitive Field Effect Transistors Applied to the Measurement of the PH of Brines by :
Download or read book Ion Sensitive Field Effect Transistors Applied to the Measurement of the PH of Brines written by and published by . This book was released on with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to measure the pH (the negative logarithm of the hydrogen ion activity) of harsh fluids such as geothermal oil field brines is important, since pH is a fundamental property; as one chemist stated: very often pH is a critical test because its accuracy lays the foundation for other measurements''. In our research, we focus on the analysis of brines similar to those found in underground geothermal reservoirs. Since the brines are deep under the ground, the values of the pressure and the temperature are high (up to 14 Mpa and 150[degrees]C); therefore the usual methods of pH measurement, e.g., glass electrode, are not applicable. The hydrogen ion sensitive ISFET (Ion Selective Field Effect Transistor) was studied as a pH sensor in this research. An ISFET can detect the electrochemical potential difference between the solution and the semiconductor due to the concentration of H[sup +] ions in the solution. Because of its solid state construction, an ISFET should work properly under high pressure and high temperature conditions. Earlier results, have indicated that it is possible to use ISFETs under the harsh conditions presented by geothermal brines.
Book Synopsis Advanced Materials and Techniques for Biosensors and Bioanalytical Applications by : Pranab Goswami
Download or read book Advanced Materials and Techniques for Biosensors and Bioanalytical Applications written by Pranab Goswami and published by CRC Press. This book was released on 2020-11-01 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioanalytical science and its technological subdomain, biosensors, are ever-evolving subjects, striving for rapid improvement in terms of performance and expanding the target range to meet the vast societal and market demands. The key performance factors for a biosensor that drive the research are selectivity, sensitivity, response time, accuracy, and reproducibility, with additional requirements of its portability and inexpensive nature. These performance factors are largely governed by the materials and techniques being used in these bioanalytical platforms. The selection of materials to meet these requirements is critical, as their interaction or involvement with the biological recognition elements should initiate or improve these performance factors. The technique discussed primarily applies to transducers involved in converting a biochemical signal to optical or electrical signals. Over the years, the emergence of novel materials and techniques has drastically improved the performance of these bioanalytical systems, enabling them to expand their analytical horizon. These advanced materials and techniques are central to modern bioanalytical and biosensor research. Advanced Materials and Techniques for Biosensors and Bioanalytical Applications provides a comprehensive review of the subject, including a knowledge platform for both academics and researchers. Considering biosensors as a central theme to this book, an outline on this subject with background principles has been included, with a scope of extending the utility of the book to coursework in graduate and postgraduate schools. Features: • Basic principles on different classes of biosensors, recent advances and applications • Smart materials for biosensors and other rapid, portable detection devices • Metal nanoparticles and nanocrystals for analytical applications • Carbon-based nanoparticles and quantum dots for sensing applications • Nanozymes as potential catalysts for sensing applications • Bioelectrochemiluminescence and photoelectrochemical-based biosensors • Paper electronics and paper-based biosensors • Microbial biosensors: artificial intelligence, genetic engineering, and synthetic biology • Biofuel cells as a signal transduction platform • FET-based biosensors, including ISFET and BioFET This book serves as a reference for scientific investigators and a textbook for a graduate-level course in biosensors and advanced bioanalytical techniques.
Book Synopsis Design and Fabrication of N-ISFET Using SI3N4/SIO2 Structure for PH Measurement by :
Download or read book Design and Fabrication of N-ISFET Using SI3N4/SIO2 Structure for PH Measurement written by and published by . This book was released on 2013 with total page 83 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this research is to design, fabricate and test Ionic Sensitive Field Effect Transistor (ISFET) for pH measurement.
Book Synopsis Design and Methodology of Isfet (ion Sensitive Field Effect Transistor) Microsystems for Bio-telemetry by : Arkadiy Morgenshtein
Download or read book Design and Methodology of Isfet (ion Sensitive Field Effect Transistor) Microsystems for Bio-telemetry written by Arkadiy Morgenshtein and published by . This book was released on 2003 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Development of Ion-sensitive Field Effect Transistors of PH and Ionic Concentration Measurement by : C. R. Hoffman
Download or read book Development of Ion-sensitive Field Effect Transistors of PH and Ionic Concentration Measurement written by C. R. Hoffman and published by . This book was released on 1985 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Characterization, Modeling, and Correction of Threshold Voltage Instability in PH-sensitive Ion-selective Field Effect Transistors (ISFET's) by : Shahriar Jamasb
Download or read book Characterization, Modeling, and Correction of Threshold Voltage Instability in PH-sensitive Ion-selective Field Effect Transistors (ISFET's) written by Shahriar Jamasb and published by . This book was released on 1998 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Development of Ion-sensitive Field Effect Transistors of PH an Ion Concentration Measurement by : C. R. Hoffman
Download or read book Development of Ion-sensitive Field Effect Transistors of PH an Ion Concentration Measurement written by C. R. Hoffman and published by . This book was released on 1985 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Development of an Ion Sensitive Field Effect Transistor Process for Research and Teaching by : Seng Fatt Chin
Download or read book Development of an Ion Sensitive Field Effect Transistor Process for Research and Teaching written by Seng Fatt Chin and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Integrated Ion Sensitive Field Effect Transistor (ISFET) Microchemical Sensor and Electrowetting on Dielectric (EWOD) Microfluidic Actuator Using Ultra-thin Zirconium Oxide and Hafnium Oxide Films by : Vladan Jankovic
Download or read book Integrated Ion Sensitive Field Effect Transistor (ISFET) Microchemical Sensor and Electrowetting on Dielectric (EWOD) Microfluidic Actuator Using Ultra-thin Zirconium Oxide and Hafnium Oxide Films written by Vladan Jankovic and published by . This book was released on 2006 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Physics and Technology of the Ion Sensitive Field Effect Transistor (ISFET) by : Hon-Sum Philip Wong
Download or read book The Physics and Technology of the Ion Sensitive Field Effect Transistor (ISFET) written by Hon-Sum Philip Wong and published by . This book was released on 1988 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Organic Transistor Devices for In Vitro Electrophysiological Applications by : Andrea Spanu
Download or read book Organic Transistor Devices for In Vitro Electrophysiological Applications written by Andrea Spanu and published by Springer. This book was released on 2016-01-22 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis reports on a novel system for extracellular recordings of the activity of excitable cells, which relies on an organic, charge-modulated field-effect transistor (FET) called OCMFET. The book shows how, thanks to the intrinsic biocompatibility, lightness, and inexpensiveness of the material used, this new system is able to overcome several problems typical of of “classic” electronic and bioelectronic. It provides a full description of the system, together with a comprehensive report of the successful experimental trials carried out on both cardiac and nerve cells, and a concise yet comprehensive overview of bioelectronic interfaces and organic sensors for electrophysiological applications.
Book Synopsis Design, Fabrication, and Testing of a PH Sensitive Field-effect Transistor Microprobe by : Samson X. Huang
Download or read book Design, Fabrication, and Testing of a PH Sensitive Field-effect Transistor Microprobe written by Samson X. Huang and published by . This book was released on 1984 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Organic Field Effect Transistors by : Ioannis Kymissis
Download or read book Organic Field Effect Transistors written by Ioannis Kymissis and published by Springer Science & Business Media. This book was released on 2008-12-25 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Field Effect Transistors presents the state of the art in organic field effect transistors (OFETs), with a particular focus on the materials and techniques useful for making integrated circuits. The monograph begins with some general background on organic semiconductors, discusses the types of organic semiconductor materials suitable for making field effect transistors, the fabrication processes used to make integrated Circuits, and appropriate methods for measurement and modeling. Organic Field Effect Transistors is written as a basic introduction to the subject for practitioners. It will also be of interest to researchers looking for references and techniques that are not part of their subject area or routine. A synthetic organic chemist, for example, who is interested in making OFETs may use the book more as a device design and characterization reference. A thin film processing electrical engineer, on the other hand, may be interested in the book to learn about what types of electron carrying organic semiconductors may be worth trying and learning more about organic semiconductor physics.
Book Synopsis Ion Sensitive Field Effect Transistors Applied to the Measurement of the PH of Brines by : Jie Chen
Download or read book Ion Sensitive Field Effect Transistors Applied to the Measurement of the PH of Brines written by Jie Chen and published by . This book was released on 1991 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Coupling Cells and Biomolecules with CMOS Floating Gate Transistors by : Krishna Jayant
Download or read book Coupling Cells and Biomolecules with CMOS Floating Gate Transistors written by Krishna Jayant and published by . This book was released on 2014 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Charge based detection of bio-analytes using field-effect-transistors (FET's) presents an attractive route towards realizing low cost, ultrasensitive and label-free electronic biosensors. The first realization of such a biosensor was based on the Ion-Sensitive Field Effect Transistor (ISFET), developed by Piet Bergveld and has been instrumental in inspiring many FET based bio-sensor designs and concepts. This thesis takes inspiration from the ISFET, builds on well understood CMOS technology, integrates neuromorphic style operation and flash memory principles to realize floating-gate ISFET's capable of charge sensing, simultaneous ionic actuation and colocalized impedance spectroscopy based detection. The device termed the Chemoreceptive Neuron MOS Transistor (C[nu]MOS) is theoretically and experimentally investigated for both biomolecular sensing and secretory analysis from cells. Chapter 1 describes a brief background to the field of ISFET based biosensing. The relative merits and challenges associated with FET based biosensing are discussed. Chapter 2 describes the sensor structure, tunneling operation and interface physics under study in this dissertation. The structure takes inspiration from multi-input floating gate memories. The interface between the transistor and the fluid is modeled incorporating effects such as surface equilibrium constants and ion size. Actuation by non-volatile charge injection is introduced and is shown to tune the pH sensitivity thus realizing a single transistor sensor-actuator hybrid. Multivalent ion induced corelations such as charge inversion is described. Chapter 3 describes the device as a DNA sensor. Physics of the DNA-transistor interface is presented. Electric field induced DNA desorption and refreshabilty is discussed. Impedance spectroscopy using split signal delivery is outlined. Chapter 4 outlines factors that affect DNA detection, role of background electrolyte composition, surface properties and methods to improve sensitivity at the transistor interface. Chapter 5 introduces the use of split signal delivery and impedance spectroscopy for ultrasensitive pathogenic DNA detection. SPICE simulations depict dominant poles and zeros in the system and their relative dependence on analyte properties. The use of branched Y-DNA motifs and target induced self-assembly are introduced as signal amplification mechanisms pushing the limits of target detection down to ~100fM on CMOS. Chapter 6 describes the coupling between excitable chromaffin cells and non-excitable RBL-2H3 mast cells with floating gate transistors. The mechanisms of electrochemical and electrical activity detection are discussed. Simultaneous charge and impedance sensing is introduced. Chapter 7 presents the conclusion and future outlook.
