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Author : Yen Geow Tan
Publisher :
ISBN 13 :
Total Pages : 90 pages
Book Rating : 4.:/5 (575 download)
Download or read book Development and Characterization of a Surface Plasmon Resonance Sensor written by Yen Geow Tan and published by . This book was released on 2004 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Leiva Casemiro Oliveira
Publisher : Springer
ISBN 13 : 3030174867
Total Pages : 326 pages
Book Rating : 4.0/5 (31 download)
Download or read book Surface Plasmon Resonance Sensors written by Leiva Casemiro Oliveira and published by Springer. This book was released on 2019-06-13 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This significantly extended second edition addresses the important physical phenomenon of Surface Plasmon Resonance (SPR) or Surface Plasmon Polaritons (SPP) in thin metal films, a phenomenon which is exploited in the design of a large variety of physico-chemical optical sensors. In this treatment, crucial materials aspects for design and optimization of SPR sensors are investigated and described in detail. The text covers a selection of nanometer thin metal films, ranging from free-electron to the platinum-type conductors, along with their combination with a large variety of dielectric substrate materials, and associated individual layer and opto-geometric arrangements. Whereas the first edition treated solely the metal-liquid interface, the SP-resonance conditions considered here are expanded to cover the metal-gas interface in the angular and wavelength interrogation modes, localized and long-range SP's and the influence of native oxidic ad-layers in the case of non-noble metals. Furthermore, a selection of metal grating structures that allow SP excitation is presented, as are features of radiative SP's. Finally, this treatise includes as-yet hardly explored SPR features of selected metal–metal and metal–dielectric superlattices. An in-depth multilayer Fresnel evaluation provides the mathematical tool for this optical analysis, which otherwise relies solely on experimentally determined electro-optical materials parameters.
Author : Sanjeev Kumar Raghuwanshi
Publisher : CRC Press
ISBN 13 : 1000485870
Total Pages : 329 pages
Book Rating : 4.0/5 (4 download)
Download or read book 2D Materials for Surface Plasmon Resonance-based Sensors written by Sanjeev Kumar Raghuwanshi and published by CRC Press. This book was released on 2021-12-12 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2D Materials for Surface Plasmon Resonance-based Sensors offers comprehensive coverage of recent design and development (including processing and fabrication) of 2D materials in the context of plasmonic-based devices. It provides a thorough overview of the basic principles and techniques used in the analysis and design of 2D material-based optical sensor systems. Beginning with the basic concepts of plasmon/plasmonic sensors and mathematical modelling, the authors explain the fundamental properties of 2D materials, including Black Phosphorus (BP), Phosphorene, Graphene, Transition metal dichalcogenides (TMDCs), MXene's and SW-CNT. It also details the applications of these emerging materials in clinical diagnosis and their future trends. This text will be useful for practising engineers, undergraduate and postgraduate students. Key Features Presents the fundamental concepts of 2D material assisted fibre optic and prism based SPR sensor in a student-friendly manner. Includes the recent synthesis and characterization techniques of 2D materials. Provides computational results of recently discovered electronic and optical properties of the 2D materials along with their effectiveness in the field of plasmonic sensors. Presents emerging applications of novel 2D material-based plasmonic sensors in the field of chemical, bio-chemical and biosensing.
Author : Jiri Homola
Publisher : Springer Science & Business Media
ISBN 13 : 3540339191
Total Pages : 253 pages
Book Rating : 4.5/5 (43 download)
Download or read book Surface Plasmon Resonance Based Sensors written by Jiri Homola and published by Springer Science & Business Media. This book was released on 2006-08-18 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive treatment of the field of SPR sensors, in three parts. Part I introduces principles of surface plasmon resonance bio-sensors, electromagnetic theory of surface plasmons, theory of SPR sensors and molecular interactions at sensor surfaces. Part II examines the development of SPR sensor instrumentation and functionalization methods. Part III reviews applications of SPR biosensors in the study of molecules, and in environmental monitoring, food safety and medical diagnostics.
Author : Leiva Casemiro Oliveira
Publisher : Springer
ISBN 13 : 3319149261
Total Pages : 188 pages
Book Rating : 4.3/5 (191 download)
Download or read book Surface Plasmon Resonance Sensors written by Leiva Casemiro Oliveira and published by Springer. This book was released on 2015-02-23 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the important physical phenomenon of Surface Plasmon Resonance or Surface Plasmon Polaritons in thin metal films, a phenomenon which is exploited in the design of a large variety of physico-chemical optical sensors. In this treatment, crucial materials aspects for design and optimization of SPR sensors are investigated and outlined in detail. The text covers the selection of nanometer thin metal films, ranging from free-electron to the platinum type conductors, along with their combination with a large variety of dielectric substrate materials, and associated individual layer and opto-geometric arrangements. Furthermore, as-yet hardly explored SPR features of selected metal–metal and metal–dielectric super lattices are included in this report. An in-depth multilayer Fresnel evaluation provides the mathematical tool for this optical analysis, which otherwise relies solely on experimentally determined electro-optical materials parameters.
Author : Christopher Francis Grant
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (43 download)
Download or read book Development and Characterization of Interfacial Chemistry for Biomolecule Immobilization in Surface Plasmon Resonance (SPR) Imaging Studies written by Christopher Francis Grant and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Richard B. M. Schasfoort
Publisher : Royal Society of Chemistry
ISBN 13 : 1782627308
Total Pages : 555 pages
Book Rating : 4.7/5 (826 download)
Download or read book Handbook of Surface Plasmon Resonance written by Richard B. M. Schasfoort and published by Royal Society of Chemistry. This book was released on 2017-05-30 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface plasmon resonance (SPR) plays a dominant role in real-time interaction sensing of biomolecular binding events, this book provides a total system description including optics, fluidics and sensor surfaces for a wide researcher audience.
Author : Laurel L. Kegel
Publisher :
ISBN 13 : 9781321715910
Total Pages : 159 pages
Book Rating : 4.7/5 (159 download)
Download or read book Characterization of Surface Plasmon Resonance (SPR) Active Nanohole Array Sensing Platforms written by Laurel L. Kegel and published by . This book was released on 2015 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface plasmon resonance (SPR) active nanohole array substrates offer a diverse biosensing platform with high sensitivity and unique characteristics. This dissertation investigates the sensitivity and fundamental SP features of various nanohole array substrates and demonstrates higher sensitivity than conventional continuous gold platforms, tunability to specific analytes, and great enhancement of the local field intensity. Novel instrumentation and analytical techniques are developed and utilized to assess the nanohole array SPR sensing substrates in the near infrared as well as with interaction of other nanostructures. The nanohole array substrates are evaluated throughout the near-infrared (NIR) region by novel SPR instrumentation and methodology that extends the working SPR wavelength range and measurement reliability. Development of a robust NIR-SPR instrument allows access to higher wavelength ranges where sensitivity is improved and novel SP modes and plasmonic materials may be investigated. Different aspects of the NIR-SPR instrument, including temporal stability, mechanical resilience and sensitivity, are evaluated and presented. Furthermore, a method is developed for improving precision and accuracy of empirically determined SP penetration depth, a merit of SPR spectroscopy sensitivity. The technique incorporates an adsorbate-metal bonding effect which improves the consistency in the penetration depth value calculated at different adsorbate thicknesses from 41-1089% relative deviation (without bonding effect) to 2-11% relative deviation (with bonding effect). It also improves the experimental agreement with theory, increases the accuracy of assessing novel plasmonic materials and nanostructures, and increases the precision in adsorbate parameters calculated from the penetration depth value, such as thickness, binding affinity, and surface coverage. Utilizing this NIR-SPR instrument and improved technique for calculation of penetration depth, the sensitivity and various SP modes of the nanohole arrays throughout the NIR range are evaluated, and an improvement in sensitivity compared to conventional continuous gold is observed. Both the Bragg SPs arising from diffraction by the periodic holes and the traditional propagating SPs are characterized with emphasis on sensing capability of the propagating SPs. There are numerous studies on the transmission spectroscopy of nanohole arrays; however this dissertation presents one of the few studies in Kretschmann mode, and the first in the near infrared, where greater surface sensitivity is observed. The sensitivity profile of various nanohole array parameters (periodicity, diameter, excitation wavelength) and SP modes is also presented. Further control and enhancement of the SP field is pursued by interaction between nanohole array substrate and nanoparticles to exploit field intensification between plasmonic structures, i.e. gap mode enhancement. Under specific conditions, the SPs couple together and the electric field between the structures is amplified and localized, which may be exploited for sensing purposes and surface enhanced techniques, including tip enhanced Raman spectroscopy (TERS) or surface enhanced Raman spectroscopy (SERS). A technique for observing nanohole array-nanoparticle distance dependent SP interaction is developed and utilized to demonstrate SP interaction. Scanning probe microscopy controls the position of a single nanoparticle (SNP) affixed to an atomic force microscope probe, and the location specific interaction of the SNP-nanohole array surface plasmons is measured by darkfield surface plasmon resonance spectroscopy. Coupling of the nanoparticle to the nanohole array exhibits a maximum when the SNP resides within a nanohole, which resulted in a maximum SPR wavelength shift of 17 nm and an increase in scatter intensity. This dissertation presents the first empirical observations of SPM controlled gap mode enhancement of more complex nanostructures and allows for optimization of positioning prior to use in sensing.
Author : Nathan George Frederick Reaver
Publisher :
ISBN 13 :
Total Pages : 252 pages
Book Rating : 4.:/5 (867 download)
Download or read book Development and Characterization of Aptamers for the Use in Surface Plasmon Resonance Sensors for the Detection of Glycated Blood Proteins written by Nathan George Frederick Reaver and published by . This book was released on 2013 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concentration ratio of glycated to non-glycated forms of various blood proteins can be used as a diagnostic measure in diabetes to determine a history of glycemic compliance. Depending on a protein's half-life in blood, compliance can be assessed from a few days to several months in the past, which can be used to provide additional therapeutic guidance. The most commonly studied glycated protein for assessing glycemic compliance is glycated hemoglobin. Current glycated protein concentration detection methods are limited in their ability to measure multiple proteins, and are susceptible to interference from other blood pathologies. In this study, DNA aptamers were developed and characterized for use in Surface Plasmon Resonance (SPR) sensors to assess the percentage of hemoglobin that is glycated in a patient. The aptamers were developed by way of a modified Systematic Evolution of Ligands by Exponential Enrichment (SELEX) process which selects DNA sequences that have a high binding affinity to a specific protein. DNA products resulting from this process were sequenced, and identified aptamers were synthesized. The SELEX process was performed multiple times. One process produced aptamers specific to a glycated form of hemoglobin, another produced aptamers specific to non-glycated hemoglobin and aptamers specific to all forms of hemoglobin. A final SELEX process produced aptamers specific to fibrinogen. Equilibrium dissociation constants for the affinity of the identified aptamers to glycated hemoglobin, hemoglobin, and fibrinogen were calculated from fitting a Langmuir binding model to experimental, real time, binding data obtained through SPR. It was determined that two aptamers, GHA1 and GHA2, were selective to glycated hemoglobin, with equilibrium dissociation constants of 11.5 nM and 51.8 nM, respectively; one aptamer, HA2, was selective to non-glycated hemoglobin, with an equilibrium dissociation constant of 187 nM; and one aptamer was selective to both glycated and non-glycated hemoglobin, with equilibrium dissociation constants for the two proteins of 36.9 nM and 35.2 nM, respectively. It was also demonstrated how these aptamers could be used in an SPR sensor. The aptamers identified in this study can potentially be used in a SPR aptamer-based biosensor for detection of glycated hemoglobin, a technology that has the potential to deliver low-cost and immediate glycemic compliance assessment in either a clinical or home setting.
Author : Richard B. M. Schasfoort
Publisher : Royal Society of Chemistry
ISBN 13 : 0854042679
Total Pages : 426 pages
Book Rating : 4.8/5 (54 download)
Download or read book Handbook of Surface Plasmon Resonance written by Richard B. M. Schasfoort and published by Royal Society of Chemistry. This book was released on 2008 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface plasmon resonance (SPR) plays a dominant role in real-time interaction sensing of biomolecular binding events. This book focuses on a total system description including optics, fluidics and sensor surfaces. It covers all commercial SPR systems in the market. It is the first of its kind and fills a gap in the technical literature as no other handbook on SPR is currently available. The final chapter discussed new trends and a vision is given for future developments and needs of the SPR market. This excellent handbook provides comprehensive information with easy to use, stand-alone chapte.
Author : 吳建霖
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (114 download)
Download or read book Fabrication and Characterization of Localized Surface Plasmon Resonance Sensors for Mid-infrared Range Applications written by 吳建霖 and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Elsevier
ISBN 13 : 0323853102
Total Pages : 424 pages
Book Rating : 4.3/5 (238 download)
Download or read book Surface Plasmon Resonance in Bioanalysis written by and published by Elsevier. This book was released on 2021-11-11 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface Plasmon Resonance in Bioanalysis, Volume 95 in the Comprehensive Analytical Chemistry series, contains a wide range of topics on the applications and new advances of surface plasmon resonance (SPR) in bioanalysis, including Surface plasmon resonance microscopy for single-cell based drug screening, Phase-Sensitive Surface Plasmon Resonance Sensors for Highly Sensitive Bioanalysis, SPR coupled to ambient mass spectrometry, Surface Plasmon Resonance Microscopy for activity detection and imaging of single cells, SPR for water pollutant detection and biofouling control, SPR imaging for cellular analysis and detection, Progress in detection of surface palsmon resonance for biorefinery technology, and more. Additional chapters cover Long-range surface plasmon resonance and its biological sensing applications and Critical issues in clinical and biomedical applications of Surface Plasmon Resonance sensing. Provides updates on the latest applications of SPR microscopy in cell analysis Covers the latest design in SPR sensing for highly sensitive bioanalysis Presents the critical issues in clinical and biomedical applications of SPR
Author : Ratna Reddy Chada
Publisher :
ISBN 13 :
Total Pages : 90 pages
Book Rating : 4.:/5 (824 download)
Download or read book Theoretical and Experimental Characterization of Plasmonic Materials and Grating Based SPR Sensing℗ written by Ratna Reddy Chada and published by . This book was released on 2012 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plasmonics, the science and technology of the plasmons, is a rapidly growing field with substantial broader impact in numerous different fields, especially for bioapplications such as bio-sensing, biophotonics and photothermal therapy. Resonance effects associated with plasmonic behavior, i.e. surface plasmon resonance (SPR) and localize surface plasmon resonance (LSPR), are of particular interest because of their strong sensitivity to the local environment. SPR sensing techniques have made great strides in terms of instrumentation development and applications. SPR-based biosensing has gained prominence for label-free sensing using optical instruments. This thesis deals with the underlying physics of plasmon resonance, resonance effects in metallic nanostructures and their applications, characterization of plasmonic material properties using different theoretical models and grating-coupled SPR sensing.^In Chapter 1, we discuss the physics of surface plasmon resonance and the excitation of surface plasmons in metal films using different coupling mechanisms such as prism, grating and waveguide coupling. A brief overview of different techniques for sensing SPR is given are discussed including wavelength, angle and intensity modulation. The fundamentals of LSPR in sub wavelength metallic nanoparticles are also discussed including its dependence on the size and shape of the particle as well as the dielectric properties of the background media. In Chapter 2, details of theoretical material characterization are presented that involve the use of Drude-Sommerfeld model and polynomial spline fits to obtain analytical expressions for experimental permittivity data. The extraction of the Drude-Sommerfeld model parameters from experimental absorption properties is demonstrated.^In Chapter 3, we discus LSPR in metallic nanoparticles and its dependence on the size, and shape of the particle as well as the dielectric property of the background environment. Details of absorption spectra of gold nanorods and core-shell particles is presented. Computational modeling of the absorption spectrum of novel micelle-based magneto-plasmonic nanoplatforms is also presented along with their use in photothermal therapy In Chapter 4, an experimental setup of a grating-coupled SPR biosensor is described. The calibration, characterization and modeling of this device is presented.
Author : Yi Chen
Publisher : Springer Nature
ISBN 13 : 9819931185
Total Pages : 391 pages
Book Rating : 4.8/5 (199 download)
Download or read book Surface Plasmon Resonance Imaging written by Yi Chen and published by Springer Nature. This book was released on 2023-07-01 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the fundamentals, instruments, methodology, and applications of surface plasmon resonance imaging (SPRi) and related techniques. It provides an overview of SPRi development and an easy-to-understand interpretation of theory and operation principles. Some unique ideas proposed by the authors to design and set up SPRi devices and methods are disclosed for the first time. Crucial manipulation experiences are also summarized here, including chip surface functionalization, sensitivity enhancement and coupling of SPRi with other analytical techniques. The application of SPRi for molecular interaction study, featuring high throughput, label-freeness, and physiologically compatible analysis, is discussed in detail. This book is of interest and useful to a wide readership in bioanalytical chemistry, molecular biology, and many related interdisciplinary fields.
Author : Ornella Sathoud
Publisher :
ISBN 13 : 9780438932159
Total Pages : 98 pages
Book Rating : 4.9/5 (321 download)
Download or read book Fabrication of a Surface Plasmon Resonance Platform for the Development of an Electrokintic Surface Plasmon Resonance (EK-SPR) Biosensor written by Ornella Sathoud and published by . This book was released on 2019 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Point-of-Care Testing (POCT) is a clinical analysis performed near the patient, rather than in a remote, dedicated laboratory. POCT is typically performed by non-laboratory personnel and the results are used for clinical decision-making. Acute Coronary syndrome (ACS) is a group of conditions that considerably decreases or stops blood flow to the heart muscle, causing the heart to be damaged or stressed. Such events cause the release of biomarkers into the blood stream. Myocardial Infarction (MI), commonly called "heart attack", is a well-known ACS that is diagnosed by measuring the change in the level of cardiac biomarkers (preferably troponin) in the blood. This dissertation presents the fabrication of a platform to be adapted as a point-of care sensor with surface plasmon resonance as the detection method. 4-aminophenylalanine is electrografted on the gold sensing surface as the linker to allow receptors immobilization on the sensing surface. Electrokinetic method is to be combined with surface plasmon resonance, to enhance the sensitivity and selectivity of a cardiac protein biosensor. Surface Plasmon Resonance (SPR) is a real time, label free optical method that measures the refractive index change when the analyte binds receptors immobilized at the surface of a metal, here gold. In this report details on how electrografting of 4-aminophenylalanine on gold thin film permits the fabrication of an SPR biosensor platform that could possibly be as a troponin biosensor. An overview on the sensing surface characterization to confirm surface modification is offered as well as the sensor performance using bovine serum albumin bovine serum albumin antibodies.
Download or read book Surface-plasmon Optical and Electrochemical Characterization of Biofunctional Surface Architectures written by and published by . This book was released on 2008 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The development and characterization of biomolecule sensor formats based on the optical technique Surface Plasmon Resonance (SPR) Spectroscopy and electrochemical methods were investigated. The study can be divided into two parts of different scope. In the first part new novel detection schemes for labeled targets were developed on the basis of the investigations in Surface-plamon Field Enhanced Spectroscopy (SPFS). The first one is SPR fluorescence imaging formats, Surface-plamon Field Enhanced Fluorescence Microscopy (SPFM). Patterned self assembled monolayers (SAMs) were prepared and used to direct the spatial distribution of biomolecules immobilized on surfaces. Here the patterned monolayers would serve as molecular templates to secure different biomolecules to known locations on a surface. The binding processed of labeled target biomolecules from solution to sensor surface were visually and kinetically recorded by the fluorescence microscope, in which fluorescence was excited by the evanescent field of propagating plasmon surface polaritons. The second format which also originates from SPFS technique, Surface-plamon Field Enhanced Fluorescence Spectrometry (SPFSm), concerns the coupling of a fluorometry to normal SPR setup. A spectrograph mounted in place of photomultiplier or microscope can provide the information of fluorescence spectrum as well as fluorescence intensity. This study also firstly demonstrated the analytical combination of surface plasmon enhanced fluorescence detection with analyte tagged by semiconducting nano- crystals (QDs). Electrochemically addressable fabrication of DNA biosensor arrays in aqueous environment was also developed. An electrochemical method was introduced for the directed in-situ assembly of various specific oligonucleotide catcher probes onto different sensing elements of a multi-electrode array in the aqueous environment of a flow cell. Surface plasmon microscopy (SPM) is utilized for the on-line recording of the various.
Author : Christian Gabriel Driau Moll
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (122 download)
Download or read book Design and Analysis of Surface Plasmon Resonance-based Sensor for Harvesting Hot Electrons Discriminated by a Schottky Barrier written by Christian Gabriel Driau Moll and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim is to assess the realization of SPR based-sensors with direct electronic transduction of plasmon-induced phenomena for low-cost, low-power and with high sensing performances for the measurement of either chemical or biological quantities. The developed SPR sensors have the objective to produce an electrical signal, based on hot electrons that are discriminated by a Schottky junction. To that end, the device will be illuminated by a light source whose wavelength matches the specific plasmonic resonance wavelength of the SPR based sensor. Thus, a precise simulation and characterization has to be done beforehand.
