Development And Applications In Solubility

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Development and Applications in Solubility

Author : Trevor M. Letcher
Publisher : Royal Society of Chemistry
ISBN 13 : 0854043721
Total Pages : 433 pages
Book Rating : 4.8/5 (54 download)

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Book Synopsis Development and Applications in Solubility by : Trevor M. Letcher

Download or read book Development and Applications in Solubility written by Trevor M. Letcher and published by Royal Society of Chemistry. This book was released on 2007 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solubility is fundamental to most areas of chemistry and is one of the most basic of thermodynamic properties. It underlies most industrial processes. Bringing together the latest developments and ideas, Developments and Applications in Solubility covers many varied and disparate topics. The book is a collection of work from leading experts in their fields and covers the theory of solubility, modelling and simulation, industrial applications and new data and recent developments relating to solubility. Of particular interest are sections on: experimental, calculated and predicted solubilities; solubility phenomena in 'green' quaternary mixtures involving ionic liquids; molecular simulation approaches to solubility; solubility impurities in cryogenic liquids and carbon dioxide in chemical processes. The book is a definitive and comprehensive reference to what is new in solubility and is ideal for researcher scientists, industrialists and academics

Biopharmaceutics Applications in Drug Development

Author : Rajesh Krishna
Publisher : Springer Science & Business Media
ISBN 13 : 038772379X
Total Pages : 416 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Biopharmaceutics Applications in Drug Development by : Rajesh Krishna

Download or read book Biopharmaceutics Applications in Drug Development written by Rajesh Krishna and published by Springer Science & Business Media. This book was released on 2007-09-20 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The highly experienced authors here present readers with step-wise, detail-conscious information to develop quality pharmaceuticals. The book is made up of carefully crafted sections introducing key concepts and advances in the areas of dissolution, BA/BE, BCS, IVIC, and product quality. It provides a specific focus on the integration of regulatory considerations and includes case histories highlighting the biopharmaceutics strategies adopted in development of successful drugs.

Water Soluble Polymers

Author : Zahid Amjad
Publisher : Springer Science & Business Media
ISBN 13 : 0306469154
Total Pages : 261 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Water Soluble Polymers by : Zahid Amjad

Download or read book Water Soluble Polymers written by Zahid Amjad and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains a series of papers originally presented at the symposium on Water Soluble Polymers: Solution Properties and Applications, sponsored by the Division of Colloids and Surface Chemistry of the American Chemical Society. The symposium took place in Las Vegas City, Nevada on 9 to 11th September, 1997 at the 214th American Chemical Society National Meeting. Recognized experts in their - spective fields were invited to speak. There was a strong attendance from academia, g- ernment, and industrial research centers. The purpose of the symposium was to present and discuss recent developments in the solution properties of water soluble polymers and their applications in aqueous systems. Water soluble polymers find applications in a number of fields of which the following may be worth mentioning: cosmetics, detergent, oral care, industrial water treatment, g- thermal, wastewater treatment, water purification and reuse, pulp and paper production, sugar refining, and many more. Moreover, water soluble polymers play vital role in the oil industry, especially in enhanced oil recovery. Water soluble polymers are also used in ag- culture and controlled release pharmaceutical applications. Therefore, a fundamental kno- edge of solution properties of these polymers is essential for most industrial scientists. An understanding of the basic phenomena involved in the application of these polymers, such as adsorption and interaction with different substrates (i. e. , tooth enamel, hair, reverse - mosis membrane, heat exchanger surfaces, etc. ) is of vital importance in developing high performance formulations for achieving optimum efficiency of the system.

Recent Developments in the Synthesis and Applications of Pyridines

Author : Parvesh Singh
Publisher : Elsevier
ISBN 13 : 0323914594
Total Pages : 650 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Recent Developments in the Synthesis and Applications of Pyridines by : Parvesh Singh

Download or read book Recent Developments in the Synthesis and Applications of Pyridines written by Parvesh Singh and published by Elsevier. This book was released on 2022-09-17 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Developments in the Synthesis and Applications of Pyridines is a comprehensive handbook for organic chemists working on innovative approaches to the synthesis of pyridines. Written by scientists in both academia and industry and designed to be a standalone reference, the book features reviews, research results and case studies on synthetic methods and applications of pyridine-based chemotypes. The book will bridge the gap between industry and academia by presenting recent innovative approaches to the synthesis of pyridines, diverse application of pyridines in drug development, heterogeneous catalysis and material science, as well as benchtop to shelf narratives of pyridine-based compounds in the industry. The role of computational chemistry in the development of pyridine-based bioactive molecules is also included. This reference is essential for researchers in organic chemistry both in academic and industrial settings, postgraduates in chemistry and medicinal chemistry. Includes a detailed review of recent research on the reactivity, synthesis and applications of pyridines Features concise accounts of the reactivity, synthetic and optimized protocols Discusses the medicinal, inorganic and polymer chemistry applications of pyridines

CRC Handbook of Solubility Parameters and Other Cohesion Parameters

Author : Allan F.M. Barton
Publisher : Routledge
ISBN 13 : 1351457195
Total Pages : 768 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis CRC Handbook of Solubility Parameters and Other Cohesion Parameters by : Allan F.M. Barton

Download or read book CRC Handbook of Solubility Parameters and Other Cohesion Parameters written by Allan F.M. Barton and published by Routledge. This book was released on 2017-10-19 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: The CRC Handbook of Solubility Parameters and Other Cohesion Parameters, Second Edition, which includes 17 new sections and 40 new data tables, incorporates information from a vast amount of material published over the last ten years. The volume is based on a bibliography of 2,900 reports, including 1,200 new citations. The detailed, careful construction of the handbook develops the concept of solubility parameters from empirical, thermodynamic, and molecular points of view and demonstrates their application to liquid, gas, solid, and polymer systems.

Computer Applications in Pharmaceutical Research and Development

Author : Sean Ekins
Publisher : John Wiley & Sons
ISBN 13 : 0470037229
Total Pages : 840 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Computer Applications in Pharmaceutical Research and Development by : Sean Ekins

Download or read book Computer Applications in Pharmaceutical Research and Development written by Sean Ekins and published by John Wiley & Sons. This book was released on 2006-07-11 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique, holistic approach covering all functions and phases of pharmaceutical research and development While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery, development, and marketing. It explains how applications are used at various stages, including bioinformatics, data mining, predicting human response to drugs, and high-throughput screening. By providing a comprehensive view, the book offers readers a unique framework and systems perspective from which they can devise strategies to thoroughly exploit the use of computers in their organizations during all phases of the discovery and development process. Chapters are organized into the following sections: * Computers in pharmaceutical research and development: a general overview * Understanding diseases: mining complex systems for knowledge * Scientific information handling and enhancing productivity * Computers in drug discovery * Computers in preclinical development * Computers in development decision making, economics, and market analysis * Computers in clinical development * Future applications and future development Each chapter is written by one or more leading experts in the field and carefully edited to ensure a consistent structure and approach throughout the book. Figures are used extensively to illustrate complex concepts and multifaceted processes. References are provided in each chapter to enable readers to continue investigating a particular topic in depth. Finally, tables of software resources are provided in many of the chapters. This is essential reading for IT professionals and scientists in the pharmaceutical industry as well as researchers involved in informatics and ADMET, drug discovery, and technology development. The book's cross-functional, all-phases approach provides a unique opportunity for a holistic analysis and assessment of computer applications in pharmaceutics.

Absorption and Drug Development

Author : Alex Avdeef
Publisher : John Wiley & Sons
ISBN 13 : 1118057457
Total Pages : 741 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Absorption and Drug Development by : Alex Avdeef

Download or read book Absorption and Drug Development written by Alex Avdeef and published by John Wiley & Sons. This book was released on 2012-05-22 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug absorption. The book emphasizes oral absorption, explaining all the physicochemical methods used today to analyze drug candidates. Moreover, the author provides expert guidance to help readers analyze the results of their studies in order to select the most promising drug candidates. This Second Edition has been thoroughly updated and revised, incorporating all the latest research findings, methods, and resources, including: Descriptions and applications of new PAMPA models, drawing on more than thirty papers published by the author's research group Two new chapters examining permeability and Caco-2/MDCK and permeability and the blood-brain barrier Expanded information and methods to support pKa determination New examples explaining the treatment of practically insoluble test compounds Additional case studies demonstrating the use of the latest physicochemical techniques New, revised, and expanded database tables throughout the book Well over 200 drawings help readers better understand difficult concepts and provide a visual guide to complex procedures. In addition, over 800 references serve as a gateway to the primary literature in the field, facilitating further research into all the topics covered in the book. This Second Edition is recommended as a reference for researchers in pharmaceutical R&D as well as in agrochemical, environmental, and other related areas of research. It is also recommended as a supplemental text for graduate courses in pharmaceutics.

Industrial Applications of Nanocrystals

Author : Shadpour Mallakpour
Publisher : Elsevier
ISBN 13 : 0128242590
Total Pages : 518 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Industrial Applications of Nanocrystals by : Shadpour Mallakpour

Download or read book Industrial Applications of Nanocrystals written by Shadpour Mallakpour and published by Elsevier. This book was released on 2022-06-23 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approx.494 pages Approx.494 pages

Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development

Author :
Publisher : Elsevier
ISBN 13 : 0323884881
Total Pages : 434 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development by :

Download or read book Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development written by and published by Elsevier. This book was released on 2022-12-02 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development provides a valuable “go-to reference for many difficult-to-solve challenges using pertinent chromatographic theory, first-hand case studies, and examples provided from academic and industry experts. This text also enables professors teaching an analytical instrumental course to introduce and instruct students about one of the most sustainable and powerful separation methods currently available. While the text has broad applicability across industrial sectors, it focuses primarily on application in the pharmaceutical industry. The book is designed to allow readers to align current HPLC/UHPLC capabilities with SFC as an orthogonal tool for project specific methods in the pharmaceutical industry. It highlights where SFC falls on the spectrum of useful chromatographic tools for routine and challenging separative methods. Experienced HPLC users who are interested in developing knowledge in orthogonal separation techniques, as well as newcomers to the field of separation science, will find this text particularly useful. Chapters address where SFC may fit the analytical needs of the pharmaceutical industry and alert the readers as to where the technique will not fit. Readers will gain an understanding of how and where SFC may be applied and adapted more routinely across the pharmaceutical industry as a ‘green’ way of undertaking separation opportunities and challenges. Areas within the pharmaceutical industry include early drug discovery, process chemistry, and late stage development and manufacturing. Describes approaches to SFC column and mobile phase selection for method development for both analytical and preparative tasks Gives practical examples of how analytical SFC enables the monitoring of synthetic reactions including unstable intermediates, chiral and achiral polar reactants and products across small and large modalities Provides need-focused case studies for pharmaceutical analysts, process chemists, and contract chemistry facilities that can benefit from monitoring or purifying polar intermediates, mutagenic impurities, nitrosamines and other reaction by-products including excipients and metabolites

Biophysical Methods for Biotherapeutics

Author : Tapan K. Das
Publisher : John Wiley & Sons
ISBN 13 : 1118354680
Total Pages : 380 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Biophysical Methods for Biotherapeutics by : Tapan K. Das

Download or read book Biophysical Methods for Biotherapeutics written by Tapan K. Das and published by John Wiley & Sons. This book was released on 2014-02-27 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a focus on practical applications of biophysical techniques, this book links fundamental biophysics to the process of biopharmaceutical development. • Helps formulation and analytical scientists in pharma and biotech better understand and use biophysical methods • Chapters organized according to the sequential nature of the drug development process • Helps formulation, analytical, and bioanalytical scientists in pharma and biotech better understand and usestrengths and limitations of biophysical methods • Explains how to use biophysical methods, the information obtained, and what needs to be presented in a regulatory filing, assess impact on quality and immunogenicity • With a focus on practical applications of biophysical techniques, this book links fundamental biophysics to the process of biopharmaceutical development.

Development and Application of Bituminous Materials for Civil Infrastructures

Author : Hui Yao
Publisher : Frontiers Media SA
ISBN 13 : 2889715418
Total Pages : 214 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Development and Application of Bituminous Materials for Civil Infrastructures by : Hui Yao

Download or read book Development and Application of Bituminous Materials for Civil Infrastructures written by Hui Yao and published by Frontiers Media SA. This book was released on 2021-10-22 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:

College Teaching and the Development of Reasoning

Author : Robert G. Fuller
Publisher : IAP
ISBN 13 : 1617352462
Total Pages : 345 pages
Book Rating : 4.6/5 (173 download)

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Book Synopsis College Teaching and the Development of Reasoning by : Robert G. Fuller

Download or read book College Teaching and the Development of Reasoning written by Robert G. Fuller and published by IAP. This book was released on 2009-10-01 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended to offer college faculty members the insights of the development of reasoning movement that enlighten physics educators in the late 1970s and led to a variety of college programs directed at improving the reasoning patterns used by college students. While the original materials were directed at physics concepts, they quickly expanded to include other sciences and the humanities and social sciences. On-going developments in the field will be included. The editors have introduced new topics, including discussions of Vygotsky's ideas in relation to those of Piaget, of science education research progress since 1978, of constructivist learning theory applied to educational computer games and of applications from anthropology to zoology. These materials are especially relevant for consideration by current university faculty in all subjects.

Liquid-Phase Extraction

Author : Colin F. Poole
Publisher : Elsevier
ISBN 13 : 0128169125
Total Pages : 818 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Liquid-Phase Extraction by : Colin F. Poole

Download or read book Liquid-Phase Extraction written by Colin F. Poole and published by Elsevier. This book was released on 2019-08-29 with total page 818 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liquid Phase Extraction thoroughly presents both existing and new techniques in liquid phase extraction. It not only provides all information laboratory scientists need for choosing and utilizing suitable sample preparation procedures for any kind of sample, but also showcases the contemporary uses of sample preparation techniques in the most important industrial and academic project environments, including countercurrent chromatography, pressurized-liquid extraction, single-drop Microextraction, and more. Written by recognized experts in their respective fields, it serves as a one-stop reference for those who need to know which technique to choose for liquid phase extraction. Used in conjunction with a similar release, Solid Phase Extraction, it allows users to master this crucial aspect of sample preparation. Defines the current state-of-the-art in extraction techniques and the methods and procedures for implementing them in laboratory practice Includes extensive referencing that facilitates the identification of key information Aimed at both entry-level scientists and those who want to explore new techniques and methods

Surfactants

Author : Olasehinde Owoseni
Publisher : BoD – Books on Demand
ISBN 13 : 1837687064
Total Pages : 168 pages
Book Rating : 4.8/5 (376 download)

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Book Synopsis Surfactants by : Olasehinde Owoseni

Download or read book Surfactants written by Olasehinde Owoseni and published by BoD – Books on Demand. This book was released on 2024-01-17 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents detailed fundamentals of surfactant systems and links these fundamentals to emerging perspectives in the field of surfactant science. Key topics include environmentally friendly surfactants, ionic liquid-based surfactants, chemically enhanced oil recovery, synergy of surfactants with clay minerals, and reactions in microheterogeneous surfactant systems. This book is an excellent resource for students, researchers, and industry professionals.

Hansen Solubility Parameters

Author : Charles M. Hansen
Publisher : CRC Press
ISBN 13 : 1420006835
Total Pages : 546 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Hansen Solubility Parameters by : Charles M. Hansen

Download or read book Hansen Solubility Parameters written by Charles M. Hansen and published by CRC Press. This book was released on 2007-06-15 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hansen solubility parameters (HSPs) are used to predict molecular affinities, solubility, and solubility-related phenomena. Revised and updated throughout, Hansen Solubility Parameters: A User's Handbook, Second Edition features the three Hansen solubility parameters for over 1200 chemicals and correlations for over 400 materials including p

Handbook of Solubility Data for Pharmaceuticals

Author : Abolghasem Jouyban
Publisher : CRC Press
ISBN 13 : 1439804885
Total Pages : 554 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Handbook of Solubility Data for Pharmaceuticals by : Abolghasem Jouyban

Download or read book Handbook of Solubility Data for Pharmaceuticals written by Abolghasem Jouyban and published by CRC Press. This book was released on 2009-08-26 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aqueous solubility is one of the major challenges in the early stages of drug discovery. One of the most common and effective methods for enhancing solubility is the addition of an organic solvent to the aqueous solution. Along with an introduction to cosolvency models, the Handbook of Solubility Data for Pharmaceuticals provides an extensive datab

Solubility of Polysaccharides

Author : Zhenbo Xu
Publisher : BoD – Books on Demand
ISBN 13 : 9535136496
Total Pages : 140 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Solubility of Polysaccharides by : Zhenbo Xu

Download or read book Solubility of Polysaccharides written by Zhenbo Xu and published by BoD – Books on Demand. This book was released on 2017-11-29 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugars, with a scientific term as saccharides, are involved in various aspects in the lives of human beings, including the sense of taste, energy for daily life, etc. Recent development in polysaccharides, as well as the background knowledge in this field, further deepens insight into their roles as healthy supplements. In this book, the principles on polysaccharides' solubility and structure, methodologies and application of polysaccharides have been reviewed. The chapters in this book include the relationship between structure and solubility of polysaccharide, the experimental and computational researches on polysaccharide solubility and the common polysaccharide, which may further aid scholars and researchers in regard to solubility of polysaccharides, methodologies and modification.