Designing Dendrimers

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Designing Dendrimers

Author : Sebastiano Campagna
Publisher : John Wiley & Sons
ISBN 13 : 1118111060
Total Pages : 726 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Designing Dendrimers by : Sebastiano Campagna

Download or read book Designing Dendrimers written by Sebastiano Campagna and published by John Wiley & Sons. This book was released on 2011-09-26 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on dendrimers has exploded in the last 15 years, moving from the establishment of synthetic methodologies, particularly in the early years up to the end of nineties, towards sophisticated and wide-ranging applications. Dendrimers play an important role in many different areas, spanning from basic synthetic approaches to artificial photosynthesis, to medicine, to catalysis. The great potential of dendrimers is well-recognized by the hundreds of papers in the field and the increasing number of patents, and stimulated developments in other areas of knowledge, including new characterization techniques. However, some basic principles and methods still continue to give a unity to the field. Although several books on dendrimers have been published during these 15 years, the very recent progresses in new areas now requires a new point of view, trying to give a unifying and comprehensive outlook of the field. Since the first dendrimer was synthesized by Vögtle in 1978, dendrimers have experienced an explosion of scientific interest because of their unique molecular architecture. This resulted in over 5,000 scientific papers and patents published by the end of 2005. The proposed book will cover both fundamental and applicative aspects of dendrimer research. Chapters devoted to basic principles, synthetic methods and strategies, and advanced characterization techniques will be integrated by chapters illustrating the full potential of dendrimers in various fields, like artificial photosynthesis, multi-redox pool systems, diagnostics, biomedical and sensing purposes, design of functional nanostructures. Particular emphasis will be devoted to possible future developments.

Dendrimers III

Author : Fritz Vögtle
Publisher : Springer
ISBN 13 : 3540449248
Total Pages : 206 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Dendrimers III by : Fritz Vögtle

Download or read book Dendrimers III written by Fritz Vögtle and published by Springer. This book was released on 2003-07-01 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following the first two volumes "Dendrimers" (TCC vol. 197) and "Dendrimers II" (TCC vol. 210), the third volume dealing with this topic is now appearing in print (the "tetralogy" on dendrimers will soon be completed with the fourth volume). The present volume comprises a collection of up-to-date reviews written by renowned pioneers of research in the dendrimer field, three of whom lectured at the 1. International Dendrimer Symposium (IDS-1 1999) in Frankfurt. A focus of this volume is the variety of material properties of soft and shape-persistent dendrimers. As its predecessors did, this volume breaks through the frontiers to neighboring disciplines and, in an interdisciplinary approach, addresses topics such as polydisperse, hyperbranched macromolecules (dendritic polymers), the analysis of shape and density by small-angle scattering techniques, finely dispersed metals (dendrimers as catalysts), and nanotechnology close to potential applications.

Dendrimers in Nanomedicine

Author : Neelesh Kumar Mehra
Publisher : CRC Press
ISBN 13 : 1000333035
Total Pages : 328 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Dendrimers in Nanomedicine by : Neelesh Kumar Mehra

Download or read book Dendrimers in Nanomedicine written by Neelesh Kumar Mehra and published by CRC Press. This book was released on 2021-03-22 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrimers, hyperbranched macromolecules, emerged just few decades ago but show promising potential as drug delivery nanocarriers, theranostic agents and gene vectors; in the pharmaceutical research and innovation area as well as in other healthcare applications. Although tremendous advancements have been made in dendrimer chemistry and their applications since their emergence, the synthesis, development and design of pure and safe dendrimer-based products have been a major challenge in this area. This book, edited by well-known researchers in the area of nanomaterials and drug-based drug delivery applications, exhaustively covers the nanotechnological aspects, concepts, properties, characterisation, application, biofate and regulatory aspects of dendrimers. It includes sixteen vivid chapters by renowned formulators, researchers and academicians from all over the world, highlighting their specialised areas of interest in the fields of chemistry, biology, pharmacy and nanomedicine. Features: • Highlights dendrimers’ advancements in nanomedicine in the development of safe healthcare and biotechnological products • Covers physicochemical aspects, biofate, drug delivery aspects and gene therapy using dendrimers • Covers biomedical application of dendrimers in the field of biological sciences • Gives examples of dendrimer–guest interaction chemistry Dendrimers in Nanomedicine: Concept, Theory and Regulatory Perspectives provides the comprehensive overview of the latest research efforts in designing, optimising, development and scale-up of dendrimer-mediated delivery systems. It analyses the key challenges of synthesis, design, molecular modelling, fundamental concepts, drug delivery aspects, analytical tools and biological fate as well as regulatory consideration to the practical use of dendrimer application. Dr. Neelesh Kumar Mehra Assistant Professor of Pharmaceutics in the Department of Pharmaceutics at the National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad, India. He has authored more than sixty peer-reviewed publications in highly reputed international journals, as well as book chapters and contributions on two patents. Dr. Mehra has 11 years of rich research and teaching experience in the formulation and development of complex, innovative biopharmaceutical products including micro- and nanotechnologies for regulated markets. Dr. Keerti Jain Assistant Professor of Pharmaceutics in the Department of Pharmaceutics, NIPER, Raebareli, India. For more than 10 years, she has been actively engaged in formulation and development of nanomedicines. Dr. Jain has supervised masters and doctoral pharmaceutics students in their research works which have been published in high quality, good impact factor journals. She has also authored more than 60 international manuscripts in peer reviewed high impact journals. In 2019, she was awarded the prestigious ICMR-Amir Shakuntala Award.

Dendrimer-Based Drug Delivery Systems

Author : Yiyun Cheng
Publisher : John Wiley & Sons
ISBN 13 : 0470460059
Total Pages : 542 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Dendrimer-Based Drug Delivery Systems by : Yiyun Cheng

Download or read book Dendrimer-Based Drug Delivery Systems written by Yiyun Cheng and published by John Wiley & Sons. This book was released on 2012-07-03 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opportunities and challenges of using dendrimers to improve drug delivery Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs. With contributions from an international team of pioneers and experts in dendrimer research, this book provides a comprehensive overview of the latest research efforts in designing and optimizing dendrimer-based drug delivery systems. The book analyzes key issues, demonstrating the critical connections that link fundamental concepts, design, synthesis, analytical methodology, and biological assessment to the practical use of dendrimers in drug delivery applications. Topics covered include: Dendrimer history Synthesis Physicochemical properties Principles of drug delivery Applications in diverse biomedical fields Dendrimer-Based Drug Delivery Systems reflects the authors' thorough review and analysis of the current literature as well as their own firsthand experience in the lab. Readers will not only discover the current state of the science, but also gain valuable insights into fruitful directions for future research. References at the end of each chapter serve as a gateway to the growing body of literature in the field, enabling readers to explore each individual topic in greater depth. Pharmaceutical and biomedical researchers will find this book a unique and essential guide to the opportunities, issues, and challenges involved in fully exploiting the potential of dendrimers to improve drug delivery.

Dendrimers in Medicine and Biotechnology

Author : U Boas
Publisher : Royal Society of Chemistry
ISBN 13 : 1847552676
Total Pages : 191 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Dendrimers in Medicine and Biotechnology by : U Boas

Download or read book Dendrimers in Medicine and Biotechnology written by U Boas and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrimers are a new class of macromolecule increasingly used in the fields of synthetic organic chemistry, biology, medicine and biotechnology. Dendrimers in Medicine and Biotechnology: New Molecular Tools looks at this exciting and rapidly growing area of science. Using an interdisciplinary approach with particular emphasis on biological applications, the book discusses the relationship between the dendrimer molecular motif and its biological properties. A general introduction to the subject of dendrimers, including definitions of terms and symbols, is provided. Subsequent sections discuss topics including dendrimers in biological systems, dendrimers as drug delivery devices, dendrimers in diagnostics and dendrimer drugs. Throughout the book examples from current research are also provided. This book will appeal to a wide range of scientists, including non specialists who require an introduction to dendrimers, as well as those wishing to know more about the application of dendrimers in the field of biology and medicine.

Dendrimer-Based Nanotherapeutics

Author : Prashant Kesharwani
Publisher : Academic Press
ISBN 13 : 0128212519
Total Pages : 484 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Dendrimer-Based Nanotherapeutics by : Prashant Kesharwani

Download or read book Dendrimer-Based Nanotherapeutics written by Prashant Kesharwani and published by Academic Press. This book was released on 2021-04-14 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine have given rise to multifunctional smart nanocarriers that can be engineered with tunable physicochemical characteristics to deliver one or more therapeutic agent(s) safely and selectively to cancer cells, including intracellular organelle-specific targeting. This book compiles the contribution of dendrimers in the field of nanotechnology to aid researchers in exploring dendrimers in the field of drug delivery and related applications. This book covers the history of the area to the most recent research. The starting chapter covers detailed information about basic properties about dendrimers i.e. properties, nomenclature, synthesis methods, types, characterization of dendrimers, safety and toxicity issues of dendrimers. Further chapters discuss the most recent advancements in the field of dendrimer i.e. dendrimer-drug conjugates, PEGylated dendrimer, dendrimer surface engineering, dendrimer hybrids, dendrimers as solubility enhancement, in targeting and delivery of drugs, as photodynamic therapy, in tissue engineering, as imaging contrast agents, as antimicrobial agents, advances in targeted dendrimers for cancer therapy and future considerations of dendrimers. Dendrimer-Based Nanotherapeutics will help the readers to understand the most recent progress in the field of dendrimer-based research, suitable for pharmaceutical scientists, advanced students, and those working in related healthcare fields. Discusses various routes such as oral, pulmonary, transdermal, delivery and local administration of dendrimer delivery of bioactive Explores a wide range of applications of dendrimer-based drug delivery using the latest advancements in nanomedicine Provides the most recent research on dendrimers as well as context and background, providing a useful resource for all levels of researcher

Dendrimers III

Author : Fritz Vögtle
Publisher : Springer
ISBN 13 : 9783642087387
Total Pages : 198 pages
Book Rating : 4.0/5 (873 download)

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Book Synopsis Dendrimers III by : Fritz Vögtle

Download or read book Dendrimers III written by Fritz Vögtle and published by Springer. This book was released on 2010-12-09 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following the first two volumes "Dendrimers" (TCC vol. 197) and "Dendrimers II" (TCC vol. 210), the third volume dealing with this topic is now appearing in print (the "tetralogy" on dendrimers will soon be completed with the fourth volume). The present volume comprises a collection of up-to-date reviews written by renowned pioneers of research in the dendrimer field, three of whom lectured at the 1. International Dendrimer Symposium (IDS-1 1999) in Frankfurt. A focus of this volume is the variety of material properties of soft and shape-persistent dendrimers. As its predecessors did, this volume breaks through the frontiers to neighboring disciplines and, in an interdisciplinary approach, addresses topics such as polydisperse, hyperbranched macromolecules (dendritic polymers), the analysis of shape and density by small-angle scattering techniques, finely dispersed metals (dendrimers as catalysts), and nanotechnology close to potential applications.

Dendrimers II

Author : Fritz Vögtle
Publisher : Springer
ISBN 13 : 3540465774
Total Pages : 317 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Dendrimers II by : Fritz Vögtle

Download or read book Dendrimers II written by Fritz Vögtle and published by Springer. This book was released on 2003-07-01 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second volume on dendrimers is again written by pioneers in the field. Their contributions illuminate the aspects of dendrimers mentioned in the subtitle, and also touch on areas beyond chemistry, namely material sciences as well as biological, medicinal, analytical, and nano aspects.

Pharmaceutical Applications of Dendrimers

Author : Abhay Singh Chauhan
Publisher : Elsevier
ISBN 13 : 0128145285
Total Pages : 398 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Pharmaceutical Applications of Dendrimers by : Abhay Singh Chauhan

Download or read book Pharmaceutical Applications of Dendrimers written by Abhay Singh Chauhan and published by Elsevier. This book was released on 2019-11-15 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in the solubilization of hydrophobic active ingredients, drug delivery, gene delivery, imaging, diagnosis and photodynamic therapy. The book discusses the diagnostic applications of dendrimers, including their use as MRI contrast agents and in the imaging of diseased areas. In addition, the anti-inflammatory, antimicrobial and antiviral properties of PPI and PAMAM are also covered, along with a discussion on photosensitizers, such as rose Bengal and protoporphyrin IX that have been delivered using PAMAM and PPI dendrimers for the treatment of cancer. This book is an important research reference for those who want to learn more about the development of dendrimer-based solutions for drug delivery. Explores the role of dendrimers in the design of dendritic nanoplatforms for targeted drug and gene delivery systems Discusses the potential of dendrimers in preformulation and formulation development Addresses both clinical and regulatory challenges in the development of dendrimer-based formulations

Dendrimers, Dendrons, and Dendritic Polymers

Author : Donald A. Tomalia
Publisher : Cambridge University Press
ISBN 13 : 1139560212
Total Pages : 423 pages
Book Rating : 4.1/5 (395 download)

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Book Synopsis Dendrimers, Dendrons, and Dendritic Polymers by : Donald A. Tomalia

Download or read book Dendrimers, Dendrons, and Dendritic Polymers written by Donald A. Tomalia and published by Cambridge University Press. This book was released on 2012-10-18 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrimer science has exploded onto the polymer science scene as the fourth major class of polymer architecture. Capturing the history of dendrimer discovery to the present day, this book addresses all the essential information for newcomers and those experienced in the field, including: • Fundamental theory, chemistry and physics of the 'dendritic state' • Synthetic strategies (click chemistry, self-assembly, and so on) • Dendron/dendrimer characterization techniques • Architecturally driven 'dendritic effects' • Developments in scientific and commercial applications • Convergence with nanotechnology, including dendrimer-based nanodevices, nanomaterials, nanotoxicology and nanomedicine • Dendrimers as a window to a new nano-periodic system. Including first-hand accounts from pre-1995 pioneers, progress in the dendrimer field is brought to life with anticipated developments for the future. This is the ideal book for researchers in both academia and industry who need a complete introduction to the 'dendritic state' with a special focus on dendrimer and dendron polymer science.

Dendrimers: A Themed Issue in Honor of Professor Donald A. Tomalia on the Occasion of His 80th Birthday

Author : Ashok Kakkar
Publisher : MDPI
ISBN 13 : 3038973785
Total Pages : 293 pages
Book Rating : 4.0/5 (389 download)

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Book Synopsis Dendrimers: A Themed Issue in Honor of Professor Donald A. Tomalia on the Occasion of His 80th Birthday by : Ashok Kakkar

Download or read book Dendrimers: A Themed Issue in Honor of Professor Donald A. Tomalia on the Occasion of His 80th Birthday written by Ashok Kakkar and published by MDPI. This book was released on 2018-12-12 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Dendrimers: A Themed Issue in Honor of Professor Donald A. Tomalia on the Occasion of His 80th Birthday" that was published in Molecules

Dendrimers in Medical Science

Author : Zahoor Ahmad Parry
Publisher : CRC Press
ISBN 13 : 1315341786
Total Pages : 139 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Dendrimers in Medical Science by : Zahoor Ahmad Parry

Download or read book Dendrimers in Medical Science written by Zahoor Ahmad Parry and published by CRC Press. This book was released on 2017-05-25 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: This valuable new book offers a new perspective on dendrimers that bridges the gap between basic research and applied nanomedicine. It explores the ultimate effectiveness of dendrimers in theranostics, a promising field that combines therapeutics and diagnostics into single multifunctional formulations used to affect therapy or treatment of a disease state. The authors examine the potential uses of dendrimers, which have proven their capabilities in local/systemic drug delivery, physical stabilization of the drug, solubility enhancement of the poorly soluble drugs, and gene delivery.

Dendrimers

Author : Claudia Maria Simonescu
Publisher : BoD – Books on Demand
ISBN 13 : 1789230586
Total Pages : 176 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Dendrimers by : Claudia Maria Simonescu

Download or read book Dendrimers written by Claudia Maria Simonescu and published by BoD – Books on Demand. This book was released on 2018-04-25 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrimers are defined as nanoscale macromolecules having a particular architecture consisting of treelike arms or branches. They are characterized by special properties that make them promising candidates in medicine, biology, materials science, synthetic organic chemistry, biotechnology, environmental engineering, optics, electronics, catalysis, electrochemistry, photochemistry, and sensors and even for production of cosmetics and personal care products. The dendrimers research field is growing day by day, and scientists are exploring new synthesis and functionalization methods in order to improve and to determine new properties and thus new applications. The main purpose of this book is to highlight the issues regarding properties and applications of dendrimers in the field of biology, medicine, liquid crystal devices, electronics, quantum devices, and self-healing technology.

Dendrimers for Drug Delivery

Author : Anil K. Sharma
Publisher : CRC Press
ISBN 13 : 135136068X
Total Pages : 406 pages
Book Rating : 4.3/5 (513 download)

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Book Synopsis Dendrimers for Drug Delivery by : Anil K. Sharma

Download or read book Dendrimers for Drug Delivery written by Anil K. Sharma and published by CRC Press. This book was released on 2018-07-27 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: With chapters from highly skilled, experienced, and renowned scientists and researchers from around the globe, Dendrimers for Drug Delivery provides an abundance of information on dendrimers and their applications in the field of drug delivery. The volume begins with an introduction to dendrimers, summarizing dendrimer applications and the striking features of dendrimers. It goes on to present the details of usual properties, structure, classification, and methods of synthesis, with relevant examples. The toxicity of dendrimers is also discussed. The chapter authors provide an exhaustive amount of information about dendrimers and their biomedical applications, including biocompatibility and toxicity aspects, a very useful feature. This informative volume will be valuable resource that will help readers to create products derived from dendrimers and navigate through the regulatory, manufacturing, and quality control hurdles. It will be an important resource for researchers, scientists, upper-level students, and industry professionals.

Dendrimers in Nanomedicine

Author : Delphine Felder-Flesch
Publisher : CRC Press
ISBN 13 : 1315340844
Total Pages : 396 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Dendrimers in Nanomedicine by : Delphine Felder-Flesch

Download or read book Dendrimers in Nanomedicine written by Delphine Felder-Flesch and published by CRC Press. This book was released on 2016-10-26 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomedicine can take advantage of the recent developments in nanobiotechnology research for the creation of platforms with superior drug carrier capabilities, selective responsiveness to the environment, unique contrast enhancement profiles, and improved accumulation at the disease site. This book provides a broad glimpse of how various dendritic nanomaterials have been designed and used as efficient tools for nanomedicine. It comprises a pedagogic introduction to dendrimers and hyperbranched systems and their classical and accelerated syntheses through cutting-edge methodologies. The chapters on dendronized magnetic nanoparticles as theranostics, dendrimers in theory (molecular simulations), siRNA delivery with dendrimers, and dendrimers for image-guided therapy, combined with chapters focused on specific types of dendrimers or hyperbranched structures, detail the cutting-edge research in nanomedicine. Finally, a detailed chapter on issues related to the pharmacokinetics and biodistribution of dendrimers helps choose the right structures for successful transfer from bench to bedside. This book will appeal to those involved in nanobiotechnology, macromolecular science, cancer therapy, tissue repair, and siRNA delivery research.

Phosphorous Dendrimers in Biology and Nanomedicine

Author : Anne-Marie Caminade
Publisher : CRC Press
ISBN 13 : 135161729X
Total Pages : 448 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Phosphorous Dendrimers in Biology and Nanomedicine by : Anne-Marie Caminade

Download or read book Phosphorous Dendrimers in Biology and Nanomedicine written by Anne-Marie Caminade and published by CRC Press. This book was released on 2018-05-03 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dendrimers, which are hyperbranched synthetic macromolecules, have attracted researchers’ increasing interest over the last three decades owing to their numerous properties, in particular, in the fields of biology and nanomedicine. This book is an up-to-date collection of the most recent achievements in the use of dendrimers in nanomedicine, exemplified by phosphorus-containing dendrimers. Starting with the synthesis and characterization of phosphorus dendrimers, the book discusses their use as biomaterials, carriers of biological entities, and anti-inflammatory drugs; in bioimaging; and against prion diseases, Alzheimer’s, HIV, and cancer. It compares phosphorus dendrimers with other types of dendrimers. Supplemented with numerous references and abundant illustrations, the book opens new perspectives for the researchers working on dendrimers.

Transition Metal-containing Dendrimers in Biomedicine

Author : Alaa S Abd-El-Aziz
Publisher : Royal Society of Chemistry
ISBN 13 : 1837671451
Total Pages : 468 pages
Book Rating : 4.8/5 (376 download)

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Book Synopsis Transition Metal-containing Dendrimers in Biomedicine by : Alaa S Abd-El-Aziz

Download or read book Transition Metal-containing Dendrimers in Biomedicine written by Alaa S Abd-El-Aziz and published by Royal Society of Chemistry. This book was released on 2023-07-19 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been increasing research into designing transition metal-containing dendrimers as innovative materials, especially in the field of biomedicine and pharmaceutical science. They have applications in biosensors and drug-delivery systems, and are now one of the leading classes in the design of therapeutics for drug-resistant diseases. This book introduces readers to a number of classes of metal-containing dendrimers, before moving onto their design and synthesis. Their applications in biomedicine are then discussed, before highlighting future research targets in this growing field. It emphasizes the synthetic strategies to design transition metal-containing dendrimers, and discusses the type of laboratory work used to examine these types of dendrimers in the fields of medicine and pharmacology, including their antimicrobial, anticancer, anti-inflammatory and antiviral activities. Transition Metal-containing Dendrimers in Biomedicine brings chemistry, biology, pharmaceutical science and medical fields together to design these future materials which will have global benefits.