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Download Design Synthesis And Characterization Of Novel Rheniumv And Technetiumv Complexes As Potential Radiopharmaceuticals full books in PDF, epub, and Kindle. Read online Design Synthesis And Characterization Of Novel Rheniumv And Technetiumv Complexes As Potential Radiopharmaceuticals ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author :
Publisher :
ISBN 13 :
Total Pages : 408 pages
Book Rating : 4.:/5 (321 download)
Download or read book South African Journal of Science written by and published by . This book was released on 2004 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Duccio Volterrani
Publisher : Springer Nature
ISBN 13 : 3031054946
Total Pages : 2241 pages
Book Rating : 4.0/5 (31 download)
Download or read book Nuclear Oncology written by Duccio Volterrani and published by Springer Nature. This book was released on 2022-10-04 with total page 2241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the role of nuclear medicine in the diagnosis, staging, and treatment of patients with specific cancers. It presents the incidence, pathophysiologic and clinical aspects of the disease, the use of nuclear imaging in diagnosis, staging requirements, management of specific tumors, and surveillance after primary treatment of cancers. It addresses the various diagnostic/therapeutic options that are currently available or are most likely to become available in the near future according to a prioritized approach, thereby keeping to a minimum the number of diagnostic imaging procedures the patient is expected to undergo. Topics include basic science, clinical applications, radionuclide therapy, radioguided surgery, heart disease in the cancer patient, and adverse effects of cancer therapy. Each clinical chapter discusses the radionuclide procedures within an integrated framework, thereby identifying the information required for effective treatment of specific tumors. The book concludes with a series of updated cases that define and expand the didactic material in the clinical application chapters. Thoroughly updated and revised, the third edition incorporates new clinical evidence validating the use of radionuclides for diagnosis and therapy in oncology, new radiotracers, and the growing integration of imaging modalities into different types of hybrid imaging. With contributions from a group of internationally distinguished practitioners, Nuclear Oncology: From Pathophysiology to Clinical Applications, Third Edition, is a valuable reference for nuclear medicine physicians, radiologists, medical and surgical oncologists, and other clinicians involved in the care and management of cancer patients.
Author : Jason S. Lewis
Publisher : Springer
ISBN 13 : 3319989472
Total Pages : 648 pages
Book Rating : 4.3/5 (199 download)
Download or read book Radiopharmaceutical Chemistry written by Jason S. Lewis and published by Springer. This book was released on 2019-04-02 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the field of radiopharmaceutical chemistry, an essential component of nuclear medicine and radiology. However, at this point, interest in the field outpaces the academic and educational infrastructure needed to train radiopharmaceutical chemists. For example, the vast majority of texts that address radiopharmaceutical chemistry do so only peripherally, focusing instead on nuclear chemistry (i.e. nuclear reactions in reactors), heavy element radiochemistry (i.e. the decomposition of radioactive waste), or solely on the clinical applications of radiopharmaceuticals (e.g. the use of PET tracers in oncology). This text fills that gap by focusing on the chemistry of radiopharmaceuticals, with key coverage of how that knowledge translates to the development of diagnostic and therapeutic radiopharmaceuticals for the clinic. The text is divided into three overarching sections: First Principles, Radiochemistry, and Special Topics. The first is a general overview covering fundamental and broad issues like “The Production of Radionuclides” and “Basics of Radiochemistry”. The second section is the main focus of the book. In this section, each chapter’s author will delve much deeper into the subject matter, covering both well established and state-of-the-art techniques in radiopharmaceutical chemistry. This section will be divided according to radionuclide and will include chapters on radiolabeling methods using all of the common nuclides employed in radiopharmaceuticals, including four chapters on the ubiquitously used fluorine-18 and a “Best of the Rest” chapter to cover emerging radionuclides. Finally, the third section of the book is dedicated to special topics with important information for radiochemists, including “Bioconjugation Methods,” “Click Chemistry in Radiochemistry”, and “Radiochemical Instrumentation.” This is an ideal educational guide for nuclear medicine physicians, radiologists, and radiopharmaceutical chemists, as well as residents and trainees in all of these areas.
Author : Ilse Zolle
Publisher : Springer Science & Business Media
ISBN 13 : 3540339906
Total Pages : 354 pages
Book Rating : 4.5/5 (43 download)
Download or read book Technetium-99m Pharmaceuticals written by Ilse Zolle and published by Springer Science & Business Media. This book was released on 2007-01-28 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioactive drug development is a multi-disciplinary task. Therefore, dedicated scientists and experts from different fields of specialisation have contributed to this book. The text reviews forty years of advances in radiopharmaceutical development based on Technetium. The first section reviews basic principles and analytic methods, and information on chemical makeup of radiopharmaceuticals. Part 2 reviews 99mTc-radiopharmaceuticals used in nuclear medicine, thoroughly outlining their chemistry, formulation, pharmacokinetics and clinical applications.
Author : IAEA.
Publisher :
ISBN 13 :
Total Pages : 378 pages
Book Rating : 4.:/5 (12 download)
Download or read book Technetium-99m Radiopharmaceuticals written by IAEA. and published by . This book was released on 2010 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technetium-99m radiopharmaceuticals will continue to have a significant impact in several areas of nuclear medicine. This publication is intended to provide a broad overview of the current status of technetium-99m radiopharmaceuticals. It includes chapters on the most advanced chemical techniques for labelling biomolecules and synthesizing suitable multifunctional ligands that will help in the development of specific radiotracers. Of special interest for the reader are details of recent research to develop technetium-99m tracers for monitoring different biological processes enabling the develo.
Author : Tod W. Speer
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 0781796938
Total Pages : 564 pages
Book Rating : 4.7/5 (817 download)
Download or read book Targeted Radionuclide Therapy written by Tod W. Speer and published by Lippincott Williams & Wilkins. This book was released on 2010-11-15 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering an overview of radioimmunotherapy, this book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy.
Author : Attila Vértes
Publisher : Springer Science & Business Media
ISBN 13 : 144190719X
Total Pages : 3762 pages
Book Rating : 4.4/5 (419 download)
Download or read book Handbook of Nuclear Chemistry written by Attila Vértes and published by Springer Science & Business Media. This book was released on 2010-12-10 with total page 3762 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised and extended 6 volume handbook set is the most comprehensive and voluminous reference work of its kind in the field of nuclear chemistry. The Handbook set covers all of the chemical aspects of nuclear science starting from the physical basics and including such diverse areas as the chemistry of transactinides and exotic atoms as well as radioactive waste management and radiopharmaceutical chemistry relevant to nuclear medicine. The nuclear methods of the investigation of chemical structure also receive ample space and attention. The international team of authors consists of scores of world-renowned experts - nuclear chemists, radiopharmaceutical chemists and physicists - from Europe, USA, and Asia. The Handbook set is an invaluable reference for nuclear scientists, biologists, chemists, physicists, physicians practicing nuclear medicine, graduate students and teachers - virtually all who are involved in the chemical and radiopharmaceutical aspects of nuclear science. The Handbook set also provides further reading via the rich selection of references.
Author : Kenji Yoshihara
Publisher : Springer
ISBN 13 : 9783540594697
Total Pages : 301 pages
Book Rating : 4.5/5 (946 download)
Download or read book Technetium and Rhenium written by Kenji Yoshihara and published by Springer. This book was released on 1995-11-15 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Steven J. Mather
Publisher : Springer Science & Business Media
ISBN 13 : 9400917686
Total Pages : 248 pages
Book Rating : 4.4/5 (9 download)
Download or read book Current Directions in Radiopharmaceutical Research and Development written by Steven J. Mather and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiophannaceutical research has recently undergone a major change in direction. In past years it has been concerned mainly with the development of perfusion tracers, the biodistribution of which reflect the regional blood flow to areas of major organs such as the heart and brain. However, a major new direction of interest now lies in the development of receptor-binding radio-tracers which can be used to perform in-vivo characterisation of diseased tissues and it is likely that much of the future research in this field will follow this direction. The difficulties in developing such tracers are considerable. The researcher must first identify a promising target for radiopharmaceutical development. High specific activity radioactive molecules must be designed and synthesised which will both bind to the target receptor with high affinity, and also have the physicochemical characteristics which will allow them to reach the target site in sufficient quantity while at the same time showing minimal uptake in non-target tissues. Thus the knowledge base required for radiophannaceutical development has now expanded beyond the limits of radiopharmaceutical chemistry to include aspects of biochemistry, molecular biology and conventional drug design. The portfolio of basic knowledge required to support current radiopharmaceutical development is changing and scientists working in this arena need to be trained in this regard. At the same time, the very latest developments in the field need to be communicated to the scientific community in order to stimulate the advancement of this exciting new direction of research.
Author : Kenneth Kam-Wing Lo
Publisher : Academic Press
ISBN 13 : 012803887X
Total Pages : 408 pages
Book Rating : 4.1/5 (28 download)
Download or read book Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells written by Kenneth Kam-Wing Lo and published by Academic Press. This book was released on 2016-12-30 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells provides a complete overview of this important research area that is perfect for both newcomers and expert researchers in the field. Through concise chapters written and edited by esteemed experts, this book brings together a comprehensive treatment of the area previously only available through scattered, lengthy review articles in the literature. Advanced topics of research are covered, with particular focus on recent advances in the biological applications of transition metal complexes, including inorganic medicine, enzyme inhibitors, antiparasital agents, and biological imaging reagents. - Geared toward researchers and students who seek an introductory overview of the field, as well as researchers working in advanced areas - Focuses on the interactions of inorganic and organometallic transition metal complexes with biological molecules and live cells - Foscuses on the fundamentals and their potential therapeutic and diagnostic applications - Covers recent biological applications of transition metal complexes, such as anticancer drugs, enzyme inhibitors, bioconjugation agents, chemical biology tools, and bioimaging reagents
Author : V Prakash Reddy
Publisher : Newnes
ISBN 13 : 044453749X
Total Pages : 331 pages
Book Rating : 4.4/5 (445 download)
Download or read book Organofluorine Compounds in Biology and Medicine written by V Prakash Reddy and published by Newnes. This book was released on 2015-01-25 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organofluorine Compounds in Biology and Medicine covers topics on biochemically relevant organofluorine compounds and their synthesis and biochemical pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly relevant to the scientific community involved in this area. - Covers the synthesis, biochemical, and therapeutic applications of organofluorine compounds - Offers a complete text on biochemically relevant organofluorine compounds and their synthesis and mechanistic pathways - Provides one of the first major reference books on the biological and medicinal applications of organofluorine chemistry
Author : Richard P. Baum
Publisher : Springer
ISBN 13 : 3540367195
Total Pages : 922 pages
Book Rating : 4.5/5 (43 download)
Download or read book Therapeutic Nuclear Medicine written by Richard P. Baum and published by Springer. This book was released on 2014-08-16 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.
Author : Swiatoslaw Trofimenko
Publisher : World Scientific
ISBN 13 : 1783261994
Total Pages : 294 pages
Book Rating : 4.7/5 (832 download)
Download or read book Scorpionates: The Coordination Chemistry Of Polypyrazolylborate Ligands written by Swiatoslaw Trofimenko and published by World Scientific. This book was released on 1999-08-16 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with polypyrazolylborates (scorpionates), a class of ligands known since 1966, but becoming rapidly popular with inorganic, organometallic and coordination chemists since 1986, because of their versatility and user-friendliness. They can be readily modified sterically and electronically through appropriate substitution on the pyrazole ring and on boron, and have led to a number of firsts in coordination chemistry (first stable CuCO complex, first monomeric MgR complex, and many other such firsts). Their denticity can range from two to four, their “Bite” can be adjusted, and additional coordinating sites can be added to the pyrazolyl rings. Over 170 different scorpionate ligands are known today, and some are published for the first time in this book.The author, Swiatoslaw Trofimenko, discovered and developed this ligand system and has written several reviews on the subject. The book is intended as a reference work, placing at the researcher's command practically all of the over 1500 references on the subject up, and into 1999, organized both according to the ligand type and according to the metal or metalloid being coordinated. It acquaints the reader with the special features of this ligand system and permits an assessment of what has been done in a given sub-area, and of which areas remain relatively unexplored. It presents procedures for ligand synthesis, and also covers their use in catalysis and in the modelling of biologically active substances.
Author : A. Davison
Publisher : Springer
ISBN 13 : 9783540062653
Total Pages : 151 pages
Book Rating : 4.0/5 (626 download)
Download or read book Three-Membered Rings written by A. Davison and published by Springer. This book was released on 1973-08-24 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jan Aaseth
Publisher : Academic Press
ISBN 13 : 0128030739
Total Pages : 390 pages
Book Rating : 4.1/5 (28 download)
Download or read book Chelation Therapy in the Treatment of Metal Intoxication written by Jan Aaseth and published by Academic Press. This book was released on 2016-04-18 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chelation Therapy in the Treatment of Metal Intoxication presents a practical guide to the use of chelation therapy, from its basic chemistry, to available chelating antidotes, and the application of chelating agents. Several metals have long been known to be toxic to humans, and continue to pose great difficulty to treat. These challenges pose particular problems in industrial settings, with lead smelting known to be associated with hemopoietic alterations and paralyses, and the inhalation of mercury vapor in mercury mining being extremely detrimental to the central nervous system. Clinical experience has demonstrated that acute and chronic human intoxications with a range of metals can be treated efficiently by administration of chelating agents. Chelation Therapy in the Treatment of Metal Intoxication describes the chemical and biological principles of chelation in the treatment of these toxic metal compounds, including new chelators such as meso-2,3-dimercaptosuccinic acid (DMSA) and D,L-2,3-dimercapto-1-propanesulfonic acid (DMPS). - Presents all the current findings on the potential for chelation as a therapy for metal intoxication - Presents practical guidelines for selecting the most appropriate chelating agent - Includes coverage on radionuclide exposure and metal storage diseases - Describes the chemical and biological principles of chelation in the treatment of toxic metal compounds
Author : John W. Hallett Jr.
Publisher : Elsevier Health Sciences
ISBN 13 : 0323074766
Total Pages : 934 pages
Book Rating : 4.3/5 (23 download)
Download or read book Comprehensive Vascular and Endovascular Surgery written by John W. Hallett Jr. and published by Elsevier Health Sciences. This book was released on 2009-09-30 with total page 934 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Vascular and Endovascular Surgery, 2nd Edition, edited by John W. Hallett, Jr., MD, FACS, Joseph L. Mills, MD, Jonothan Earnshaw, DM, FRCS, Jim A. Reekers, MD, PhD, and Thom Rooke, MD delivers in-depth, clinically focused coverage of all aspects of vascular surgery in an exceptionally well-designed single reference. Each disease chapter follows the same consistent format, for quick consultation and better comprehension. The revised 2nd Edition features several new chapters, increased endovascular treatment coverage, and updated data from the latest trials...bringing you the newest advances from the field. More than 1,000 photographs, line drawings and tables-including many revised illustrations now in color-depict key concepts and procedures. With its practical user friendly approach-and online access through Expert Consult functionality-this resource offers convenient access to complete guidance. Presents the work of a team of nearly 80 internationally respected vascular surgeons and interventional radiologists who focus on the issues and challenges you face in everyday practice. Uses a highly structured, templated format in each chapter to quickly and consistently deliver information on basic science, clinical presentation, non-invasive testing, medical management, surgical management, complications, outcome, and follow up-making information easy to access and understand. Includes Key Points boxes in every chapter that allow for quick reference and efficient study. Features over 1,000 photographs, line drawings, charts and tables that make important information easy to comprehend. Integrates clinical information with basic science making the material relevant to everyday practice. Covers treatment and interventions from an evidence-based perspective, whenever possible. Provides short, clinical vignettes in the same style as those found on oral exams. Provides online access to the text via expertconsult.com where you can perform quick searches of the complete contents, download all of the images, further your study with bonus review and self assessment questions, and follow links to PubMed abstracts for convenient consultation whwere and when you need it most. Offers new chapters on vascular diagnosis, graft infections, aortic dissection, and visceral aneurysms for greater coverage of the field. Includes a significant increase in endovascular treatment coverage in many of the chapters, reflecting the growing need for experience in these procedures. Presents current data from DREAM and EVAR 1 and 2 trials. Features a revised artwork program-including many revised illustrations and former black and white images now in color-for an enhanced visual understanding of concepts. Includes bonus review and self assessment questions accompany the online version.
Author : Ingolf Sack
Publisher : Springer
ISBN 13 : 9783031618451
Total Pages : 0 pages
Book Rating : 4.6/5 (184 download)
Download or read book Quantification of Biophysical Parameters in Medical Imaging written by Ingolf Sack and published by Springer. This book was released on 2024-11-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this book offers six new chapters covering the latest developments in quantitative medical imaging, including artificial intelligence, MRI mapping, sonography, elastography and cardiac CT. All the other existing chapters have been updated and expanded, many with new text and figures, to reflect the rapid translation and advancement of technology in this exciting area of biomedical research. This updated edition presents fundamental knowledge on the imaging quantification of biophysical parameters for clinical diagnostic purposes. Clinical imaging scanners are considered by the authors as physical measurement systems capable of quantifying intrinsic parameters for the representation of the constitution and biophysical properties of tissues in vivo. In one respect, this approach fosters the development of new imaging methods for highly reproducible, system-independent, and quantitative biomarkers. These methods are greatly detailed in the book. Alternatively, this new edition equips the reader with a better understanding of how the physical properties of tissues interact with signal generation in medical imaging, opening up new insights into the complex and fascinating relationship between structure and function in living tissues. This updated edition is of interest to all those who recognize the limitations of clinical diagnosis based primarily on visual inspection of images, and who wish to learn more about the diagnostic potential of quantitative, biophysically-based medical imaging markers, as well as the challenges posed by the scarcity of such markers for next-generation imaging technologies.
