Design Fabrication And Testing Of A Microfluidic System For Cardiac Cell Culture

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Design, Fabrication, and Characterization of Multifunctional Nanomaterials

Author : Sabu Thomas
Publisher : Elsevier
ISBN 13 : 012820883X
Total Pages : 610 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Design, Fabrication, and Characterization of Multifunctional Nanomaterials by : Sabu Thomas

Download or read book Design, Fabrication, and Characterization of Multifunctional Nanomaterials written by Sabu Thomas and published by Elsevier. This book was released on 2021-11-24 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design, Fabrication, and Characterization of Multifunctional Nanomaterials covers major techniques for the design, synthesis, and development of multifunctional nanomaterials. The chapters highlight the main characterization techniques, including X-ray diffraction, scanning electron microscopy, high-resolution transmission electron microscopy, energy dispersive X-ray spectroscopy, and scanning probe microscopy.The book explores major synthesis methods and functional studies, including: - Brillouin spectroscopy; - Temperature-dependent Raman spectroscopic studies; - Magnetic, ferroelectric, and magneto-electric coupling analysis; - Organ-on-a-chip methods for testing nanomaterials; - Magnetron sputtering techniques; - Pulsed laser deposition techniques; - Positron annihilation spectroscopy to prove defects in nanomaterials; - Electroanalytic techniques. This is an important reference source for materials science students, scientists, and engineers who are looking to increase their understanding of design and fabrication techniques for a range of multifunctional nanomaterials. - Explains the major design and fabrication techniques and processes for a range of multifunctional nanomaterials; - Demonstrates the design and development of magnetic, ferroelectric, multiferroic, and carbon nanomaterials for electronic applications, energy generation, and storage; - Green synthesis techniques and the development of nanofibers and thin films are also emphasized.

Microfluidics for Cellular Applications

Author : Gerardo Perozziello
Publisher : Elsevier
ISBN 13 : 0128224975
Total Pages : 433 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Microfluidics for Cellular Applications by : Gerardo Perozziello

Download or read book Microfluidics for Cellular Applications written by Gerardo Perozziello and published by Elsevier. This book was released on 2023-04-13 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidics for Cellular Applications describes microfluidic devices for cell screening from a physical, technological and applications point-of-view, presenting a comparison with the cell microenvironment and conventional instruments used in medicine. Microfluidic technologies, protocols, devices for cell screening and treatment have reached an advanced state but are mainly used in research. Sections break them down into practical applications and conventional medical procedures and offers insights and analysis on how higher resolutions and fast operations can be reached. This is an important resource for those from an engineering and technology background who want to understand more and gain additional insights on cell screening processes. - Outlines the major applications of microfluidic devices in medicine and biotechnology - Assesses the major challenges of using microfluidic devices in terms of complexity of the control set-up, ease of use, integration capability, automation level, analysis throughput, content and costs - Describes the major fabrication techniques for assembling effective microfluidic devices for bioapplications

Organ-on-a-chip

Author : Julia Hoeng
Publisher : Academic Press
ISBN 13 : 0128172037
Total Pages : 545 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Organ-on-a-chip by : Julia Hoeng

Download or read book Organ-on-a-chip written by Julia Hoeng and published by Academic Press. This book was released on 2019-11-09 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organ-on-a-Chip: Engineered Microenvironments for Safety and Efficacy Testing contains chapters from world-leading researchers in the field of organ on a chip development and applications, with perspectives from life sciences, medicine, physiology and engineering. The book contains an overview of the field, with sections covering the major organ systems and currently available technologies, platforms and methods. As readers may also be interested in creating biochips, materials and engineering best practice, these topics are also described. Users will learn about the limitations of 2D in-vitro models and the available 3D in-vitro models (what benefits they offer and some examples). Finally, the MOC section shows how the organ on a chip technology can be adapted to improve the physiology of in-vitro models. - Includes case studies of other organs on a chip that have been developed and successfully used - Provides insights into functional microphysiological organ on a chip platforms for toxicity and efficacy testing, along with opportunities for translational medicine - Presented fields (PK/PD, physiology, medicine, safety) are given a definition followed by the challenges and potential of organs on a chip

Microfluidics and Nanofluidics

Author : Mohsen Sheikholeslami Kandelousi
Publisher : BoD – Books on Demand
ISBN 13 : 1789235405
Total Pages : 320 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Microfluidics and Nanofluidics by : Mohsen Sheikholeslami Kandelousi

Download or read book Microfluidics and Nanofluidics written by Mohsen Sheikholeslami Kandelousi and published by BoD – Books on Demand. This book was released on 2018-08-22 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the present book, various applications of microfluidics and nanofluidics are introduced. Microfluidics and nanofluidics span a broad array of disciplines including mechanical, materials, and electrical engineering, surface science, chemistry, physics and biology. Also, this book deals with transport and interactions of colloidal particles and biomolecules in microchannels, which have great importance to many microfluidic applications, such as drug delivery in life science, microchannel heat exchangers in electronic cooling, and food processing industry. Furthermore, this book focuses on a detailed description of the thermal transport behavior, challenges and implications that involve the development and use of HTFs under the influence of atomistic-scale structures and industrial applications.

Microfluidic Cell Culture Systems

Author : Jeffrey T Borenstein
Publisher : Elsevier
ISBN 13 : 0128136723
Total Pages : 398 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Microfluidic Cell Culture Systems by : Jeffrey T Borenstein

Download or read book Microfluidic Cell Culture Systems written by Jeffrey T Borenstein and published by Elsevier. This book was released on 2018-09-12 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Techniques for microfabricating intricate microfluidic structures that mimic the microenvironment of tissues and organs, combined with the development of biomaterials with carefully engineered surface properties, have enabled new paradigms in and cell culture-based models for human diseases. The dimensions of surface features and fluidic channels made accessible by these techniques are well-suited to the size scale of biological cells. Microfluidic Cell Culture Systems applies design and experimental techniques used in in microfluidics, and cell culture technologies to organ-on-chip systems. This book is intended to serve as a professional reference, providing a practical guide to design and fabrication of microfluidic systems and biomaterials for use in cell culture systems and human organ models. The book covers topics ranging from academic first principles of microfluidic design, to clinical translation strategies for cell culture protocols. The goal is to help professionals coming from an engineering background to adapt their expertise for use in cell culture and organ models applications, and likewise to help biologists to design and employ microfluidic technologies in their cell culture systems. This 2nd edition contains new material that strengthens the focus on in vitro models useful for drug discovery and development. One new chapter reviews liver organ models from an industry perspective, while others cover new technologies for scaling these models and for multi-organ systems. Other new chapters highlight the development of organ models and systems for specific applications in disease modeling and drug safety. Previous chapters have been revised to reflect the latest advances. - Provides design and operation methodology for microfluidic and microfabricated materials and devices for organ-on-chip disease and safety models. This is a rapidly expanding field that will continue to grow along with advances in cell biology and microfluidics technologies. - Comprehensively covers strategies and techniques ranging from academic first principles to industrial scale-up approaches. Readers will gain insight into cell-material interactions, microfluidic flow, and design principles. - Offers three fundamental types of information: 1) design principles, 2) operation techniques, and 3) background information/perspectives. The book is carefully designed to strike a balance between these three areas, so it will be of use to a broad range of readers with different technical interests and educational levels.

Microfluidic Cell Culture Systems

Author : Christopher Bettinger
Publisher : William Andrew
ISBN 13 : 9781437734591
Total Pages : 0 pages
Book Rating : 4.7/5 (345 download)

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Book Synopsis Microfluidic Cell Culture Systems by : Christopher Bettinger

Download or read book Microfluidic Cell Culture Systems written by Christopher Bettinger and published by William Andrew. This book was released on 2012-12-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fields of microfluidics and BioMEMS are significantly impacting cell biology research and applications through the application of engineering solutions to human disease and health problems. The dimensions of microfluidic channels are well suited to the physical scale of biological cells, and the many advantages of microfluidics make it an attractive platform for new techniques in biology. This new professional reference applies the techniques of microsystems to cell culture applications. The authors provide a thoroughly practical guide to the principles of microfluidic device design and operation and their application to cell culture techniques. The resulting book is crammed with strategies and techniques that can be immediately deployed in the lab. Equally, the insights into cell culture applications will provide those involved in traditional microfluidics and BioMEMS with an understanding of the specific demands and opportunities presented by biological applications. The goal is to guide new and interested researchers and technology developers to the important areas and state-of-the-practice strategies that will enhance the efficiency and value of their technologies, devices and biomedical products.

CMOS Capacitive Sensors for Lab-on-Chip Applications

Author : Ebrahim Ghafar-Zadeh
Publisher : Springer Science & Business Media
ISBN 13 : 9048137276
Total Pages : 154 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis CMOS Capacitive Sensors for Lab-on-Chip Applications by : Ebrahim Ghafar-Zadeh

Download or read book CMOS Capacitive Sensors for Lab-on-Chip Applications written by Ebrahim Ghafar-Zadeh and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1.1 Overview of Lab-on-Chip Laboratory-on-Chip (LoC) is a multidisciplinary approach used for the miniaturization, integration and automation of biological assays or procedures in analytical chemistry [1–3]. Biology and chemistry are experimental sciences that are continuing to evolve and develop new protocols. Each protocol offers step-by-step laboratory instructions, lists of the necessary equipments and required biological and/or chemical substances [4–7]. A biological or chemical laboratory contains various pieces of equipment used for performing such protocols and, as shown in Fig. 1.1, the engineering aspect of LoC design is aiming to embed all these components in a single chip for single-purpose applications. 1.1.1 Main Objectives of LoC Systems Several clear advantages of this technology over conventional approaches, including portability, full automation, ease of operation, low sample consumption and fast assays time, make LoC suitable for many applications including. 1.1.1.1 Highly Throughput Screening To conduct an experiment, a researcher fills a well with the required biological or chemical analytes and keeps the sample in an incubator for some time to allowing the sample to react properly. Afterwards, any changes can be observed using a microscope. In order to quickly conduct millions of biochemical or pharmacolo- cal tests, the researchers will require an automated highly throughput screening (HTS) [8], comprised of a large array of wells, liquid handling devices (e.g., mic- channel, micropump and microvalves [9–11]), a fully controllable incubator and an integrated sensor array, along with the appropriate readout system.

Nanotechnology for Microfluidics

Author : Xingyu Jiang
Publisher : John Wiley & Sons
ISBN 13 : 3527345337
Total Pages : 444 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Nanotechnology for Microfluidics by : Xingyu Jiang

Download or read book Nanotechnology for Microfluidics written by Xingyu Jiang and published by John Wiley & Sons. This book was released on 2020-09-08 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book focuses on microfluidics with applications in nanotechnology. The first part summarizes the recent advances and achievements in the field of microfluidic technology, with emphasize on the the influence of nanotechnology. The second part introduces various applications of microfluidics in nanotechnology, such as drug delivery, tissue engineering and biomedical diagnosis.

Microfluidic Organ-on-a-Chip: Revolutionary Platforms for Disease Comprehension and Treatment

Author : Shi-Cong Tao
Publisher : Frontiers Media SA
ISBN 13 : 2889740285
Total Pages : 176 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Microfluidic Organ-on-a-Chip: Revolutionary Platforms for Disease Comprehension and Treatment by : Shi-Cong Tao

Download or read book Microfluidic Organ-on-a-Chip: Revolutionary Platforms for Disease Comprehension and Treatment written by Shi-Cong Tao and published by Frontiers Media SA. This book was released on 2022-01-11 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Existing culture systems have a limited ability to reproduce the complicated and dynamic microenvironment of a functioning organ. To solve the issues of conventional culture techniques, multidisciplinary researchers, involving medical doctors, stem cell and developmental biology experts, engineers and physical scientists, have emerged to innovate methods and devices. A microfluidic organ-on-a-chip (μOOC) is a cell culture device, based on microfluidic technology, which contains continuously perfused chambers with cells to simulate organ-level physiology/pathology. The μOOC is not to build a whole living organ, but rather to synthesize minimal functional units that recapitulate organ-/tissue-level functions. The μOOC can be applied to study not only the convention stimulation on cells by molecular/drugs, but also physical forces (fluid shear stress, cyclic strain and mechanical compression), organ-specific cell-cell intercommunication, and organ-organ coupling responses. There is an emerging need for innovative approaches for the production, control, analysis, and utilization of the μOOC, and even the multiple interconnected μOOC (Human-on-a-Chip). Although the μOOC has attracted much attention and is continuous being studied, there are still many difficult problems to be solved. Some of the most mentioned challenges include microenvironmental (biochemical, biophysical, biomechanical, nutrient, etc.) control, modeling tissue–tissue and multiorgan interactions, and reducing variability (automated control, high-throughput manipulation/analysis, integration of biosensing and etc.).

Biomaterials- and Microfluidics-Based Tissue Engineered 3D Models

Author : J. Miguel Oliveira
Publisher : Springer Nature
ISBN 13 : 3030365883
Total Pages : 176 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Biomaterials- and Microfluidics-Based Tissue Engineered 3D Models by : J. Miguel Oliveira

Download or read book Biomaterials- and Microfluidics-Based Tissue Engineered 3D Models written by J. Miguel Oliveira and published by Springer Nature. This book was released on 2020-04-13 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume reviews the latest advances on relevant 3D tissue engineered in vitro models of disease making use of biomaterials and microfluidics. The main focus of this book is on advanced biomaterials and microfluidics technologies that have been used in in vitro mimetic 3D models of human diseases and show great promise in revolutionizing personalized medicine. Readers will discover important topics involving biomaterials and microfluidics design, advanced processing techniques, and development and validation of organ- and body-on-a-chip models for bone, liver, and cancer research. An in depth discussion of microfabrication methods for microfluidics development is also provided. This work is edited by two truly multidisciplinary scientists and includes important contributions from well-known experts in their fields. The work is written for both early stage and experienced researchers, and well-established scientists enrolled in the fields of biomaterials, microfluidics, and tissue engineering, and is especially suited to those who wish to become acquainted with the principles and latest developments of in vitro models of diseases, such as professionals working in pharma, medicine, and engineering.

Handbook of Manufacturing Systems and Design

Author : Uzair Khaleeq uz Zaman
Publisher : CRC Press
ISBN 13 : 1000959872
Total Pages : 293 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Handbook of Manufacturing Systems and Design by : Uzair Khaleeq uz Zaman

Download or read book Handbook of Manufacturing Systems and Design written by Uzair Khaleeq uz Zaman and published by CRC Press. This book was released on 2023-08-24 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of manufacturing systems, their role in product/process design, and their interconnection with an Industry 4.0 perspective, especially related to design, manufacturing, and operations. Handbook of Manufacturing Systems and Design: An Industry 4.0 Perspective provides the knowledge related to the theories and concepts of Industry 4.0. It focuses on the different types of manufacturing systems in Industry 4.0 along with associated design, and control strategies. It concentrates on the operations in Industry 4.0 with a particular focus on supply chain, logistics, risk management, and reverse engineering perspectives. Offering basic concepts and applications through to advanced topics, the handbook feeds into the goal of being a source of knowledge as well as a vehicle to explore the future possibilities of design, techniques, methods, and operations associated with Industry 4.0. Concepts with practical applications in the form of case studies are added to each chapter to round out the many attributes this handbook offers. This handbook targets students, engineers, managers, designers, and manufacturers, and will assist in their understanding of the core concepts of manufacturing systems in connection with Industry 4.0 and optimize alignment between supply and demand in real time for effective implementation of the design concepts.

Analytical Instrumentation Handbook

Author : Jack Cazes
Publisher : CRC Press
ISBN 13 : 0849390397
Total Pages : 1066 pages
Book Rating : 4.8/5 (493 download)

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Book Synopsis Analytical Instrumentation Handbook by : Jack Cazes

Download or read book Analytical Instrumentation Handbook written by Jack Cazes and published by CRC Press. This book was released on 2004-11-30 with total page 1066 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compiled by the editor of Dekker's distinguished Chromatographic Science series, this reader-friendly reference is as a unique and stand-alone guide for anyone requiring clear instruction on the most frequently utilized analytical instrumentation techniques. More than just a catalog of commercially available instruments, the chapters are wri

Lab-on-a-Chip Fabrication and Application

Author : Margarita Stoytcheva
Publisher : BoD – Books on Demand
ISBN 13 : 9535124579
Total Pages : 210 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Lab-on-a-Chip Fabrication and Application by : Margarita Stoytcheva

Download or read book Lab-on-a-Chip Fabrication and Application written by Margarita Stoytcheva and published by BoD – Books on Demand. This book was released on 2016-06-29 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: The necessity of on-site, fast, sensitive, and cheap complex laboratory analysis, associated with the advances in the microfabrication technologies and the microfluidics, made it possible for the creation of the innovative device lab-on-a-chip (LOC), by which we would be able to scale a single or multiple laboratory processes down to a chip format. The present book is dedicated to the LOC devices from two points of view: LOC fabrication and LOC application.

Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery

Author : Paul C.H. Li
Publisher : CRC Press
ISBN 13 : 142002745X
Total Pages : 529 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery by : Paul C.H. Li

Download or read book Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery written by Paul C.H. Li and published by CRC Press. This book was released on 2005-11-01 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microfluidic lab-on-a-chip allows scientists to conduct chemical and biochemical analysis in a miniaturized format so small that properties and effects are successfully enhanced, and processes seamlessly integrated. This microscale advantage translates into greater sensitivity, more accurate results, and better information. Microfluidic

Microsystems for Enhanced Control of Cell Behavior

Author : Andrés Díaz Lantada
Publisher : Springer
ISBN 13 : 3319293281
Total Pages : 457 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Microsystems for Enhanced Control of Cell Behavior by : Andrés Díaz Lantada

Download or read book Microsystems for Enhanced Control of Cell Behavior written by Andrés Díaz Lantada and published by Springer. This book was released on 2016-03-23 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook focuses on the entire development process of biomedical microsystems that promote special interactions with cells. Fundamentals of cell biology and mechanobiology are described as necessary preparatory input for design tasks. Advanced design, simulation, and micro/nanomanufacturing resources, whose combined use enables the development of biomedical microsystems capable of interacting at a cellular level, are covered in depth. A detailed series of chapters is then devoted to applications based on microsystems that offer enhanced cellular control, including microfluidic devices for diagnosis and therapy, cell-based sensors and actuators (smart biodevices), microstructured prostheses for improvement of biocompatibility, microstructured and microtextured cell culture matrices for promotion of cell growth and differentiation, electrophoretic microsystems for study of cell mechanics, microstructured and microtextured biodevices for study of cell adhesion and dynamics, and biomimetic microsystems (including organs-on-chips), among others. Challenges relating to the development of reliable in vitro biomimetic microsystems, the design and manufacture of complex geometries, and biofabrication are also discussed.

Biochip Technology

Author : Jing Cheng
Publisher : CRC Press
ISBN 13 : 0203305043
Total Pages : 453 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Biochip Technology by : Jing Cheng

Download or read book Biochip Technology written by Jing Cheng and published by CRC Press. This book was released on 2003-09-02 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochip technology has experienced explosive growth in recent years and Biochip technology describes the basic manufacturing and fabrication processes and the current range of applications of these chips. Top scientists from the biochip industry and related areas explain the diverse applications of biochips in gene sequencing, expression monitoring, disease diagnosis, tumor examination, ligand assay and drug discovery.

Lab-on-a-Chip Devices and Micro-Total Analysis Systems

Author : Jaime Castillo-León
Publisher : Springer
ISBN 13 : 3319086871
Total Pages : 246 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Lab-on-a-Chip Devices and Micro-Total Analysis Systems by : Jaime Castillo-León

Download or read book Lab-on-a-Chip Devices and Micro-Total Analysis Systems written by Jaime Castillo-León and published by Springer. This book was released on 2014-11-05 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all the steps in order to fabricate a lab-on-a-chip device starting from the idea, the design, simulation, fabrication and final evaluation. Additionally, it includes basic theory on microfluidics essential to understand how fluids behave at such reduced scale. Examples of successful histories of lab-on-a-chip systems that made an impact in fields like biomedicine and life sciences are also provided. This book also: · Provides readers with a unique approach and toolset for lab-on-a-chip development in terms of materials, fabrication techniques, and components · Discusses novel materials and techniques, such as paper-based devices and synthesis of chemical compounds on-chip · Covers the four key aspects of development: basic theory, design, fabrication, and testing · Provides readers with a comprehensive list of the most important journals, blogs, forums, and conferences where microfluidics and lab-on-a-chip news, methods, techniques and challenges are presented and discussed, as well as a list of companies providing design and simulation support, components, and/or developing lab-on-a-chip and microfluidic devices.