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Design And Applications Of Microneedles In Drug Delivery And Therapeutics
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Book Synopsis Design and Applications of Microneedles in Drug Delivery and Therapeutics by : Prashant Kesharwani
Download or read book Design and Applications of Microneedles in Drug Delivery and Therapeutics written by Prashant Kesharwani and published by Elsevier. This book was released on 2024-06-28 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microneedles in Drug Delivery and Therapeutics details the design, characterization and applications of this novel drug delivery system.Microneedles offer several advantages over traditional oral and parenteral approaches, due to their ability to be fabricated and altered in shape, size and material type, matched to specific treatment needs.This book covers the materials selection, design and fabrication approaches, and clinical translation of microneedles for a range of therapeutic applications, including: cancer therapy, gene and vaccine delivery, wound healing and more. Microneedles in Drug Delivery and Therapeutics is a forward-thinking resource for those working in the development of materials and devices for novel drug delivery. - Introduces the reader to skin anatomy and materials development in regard to microneedles as smart carriers for drug delivery, offering an interdisciplinary approach that will appeal to a wide audience - Covers a broad range of therapeutic applications, from ocular diseases and photodynamic therapy to sensing and cancer treatment - Provides an overview of the materials, design, fabrication, clinical translation, commercial aspects of microneedle development, and their applications in drug delivery
Book Synopsis Microneedle-mediated Transdermal and Intradermal Drug Delivery by : Ryan F. Donnelly
Download or read book Microneedle-mediated Transdermal and Intradermal Drug Delivery written by Ryan F. Donnelly and published by John Wiley & Sons. This book was released on 2012-01-17 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microneedles can be used for delivery of a wide range of drug substances for practically any medical condition and present a real opportunity for vaccines and medicines that are unsuitable for oral administration or conventional patch delivery. Microneedle-mediated Transdermal and Intradermal Drug Delivery covers the major aspects relating to the use of microneedle arrays in enhancing drug delivery applications. It provides an overview of the various methods employed to design and produce microneedles, from the different materials involved to the importance of application methods. It carefully and critically reviews ongoing transdermal and intradermal delivery research using microneedles and includes the outcomes of in vivo animal and human studies. Importantly, it also discusses the safety and patient acceptability studies carried out to date. Finally, the book reviews the recent patents in microneedle research and describes the ongoing developments within industry that will determine the future of microneedle-mediated transdermal and intradermal drug delivery. By an expert author team with practical experience in the design and development of drug delivery systems this is the only text that provides a comprehensive review of microneedle research in transdermal and intradermal drug delivery.
Book Synopsis Microneedles for Drug and Vaccine Delivery and Patient Monitoring by : Ryan F. Donnelly
Download or read book Microneedles for Drug and Vaccine Delivery and Patient Monitoring written by Ryan F. Donnelly and published by John Wiley & Sons. This book was released on 2018-08-20 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive coverage of microneedles for delivering and monitoring patient drugs and vaccines Microneedles are an incredibly active research area and have the potential to revolutionize the way many medicines and vaccines are delivered. This comprehensive research book covers the major aspects relating to the use of microneedle arrays in enhancing both transdermal and intradermal drug delivery and provides a sound background to the use of microneedle arrays in enhanced delivery applications. Beginning with a history of the field and the various methods employed to produce microneedles from different materials, Microneedles for Drug and Vaccine Delivery and Patient Monitoring discusses the penetration of the stratum corneum by microneedles and the importance of application method and force and microneedle geometry (height, shape, inter-needle spacing). Transdermal and intradermal delivery research using microneedles is comprehensively and critically reviewed, focusing on the outcomes of in vivo animal and human studies. The book describes the important topics of safety and patient acceptability studies carried out to date. It also covers in detail the growing area for microneedle use in the monitoring of interstitial fluid contents. Finally, it reviews translational and regulatory developments in the microneedles field and describes the work ongoing in industry. The only book currently available on microneedles Filled with tables, graphs, and black and white images (photographs, micrographs) Authored by four experts in pharmaceutics Microneedles for Drug and Vaccine Delivery and Patient Monitoring is an ideal source for researchers in industry and academia working on drug delivery and transdermal delivery in particular, as well as for advanced students in pharmacy and pharmaceutical sciences.
Book Synopsis Drug Delivery Devices and Therapeutic Systems by : Eric Chappel
Download or read book Drug Delivery Devices and Therapeutic Systems written by Eric Chappel and published by Academic Press. This book was released on 2020-11-07 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Delivery Devices and Therapeutic Systems examines the current technology and innovations moving drug delivery systems (DDS) forward. The book provides an overview on the therapeutic use of drug delivery devices, including design, applications, and a description of the design of each device. While other books focus on the therapy, the primary emphasis in this book is on current technologies for DDS applications, including microfluidics, nanotechnology, biodegradable hydrogel and microneedles, with a special emphasis on wearable DDS. As part of the Developments in Biomedical Engineering and Bioelectronics series, this book is written by experts in the field and informed with information directly from manufacturers. Pharmaceutical scientists, medical researchers, biomedical engineers and clinical professionals will find this an essential reference. - Provides essential information on the most recent drug delivery systems available - Explains current technology and its applications to drug delivery - Contains contributions from biomedical engineers, pharmaceutical scientists and manufacturers
Download or read book Microneedles written by Hiep Xuan Nguyen and published by CRC Press. This book was released on 2023-07-04 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microneedle field has been expanding exponentially with innovative designs and various applications, thus capturing the interest of academic industry and regulatory sectors. Microneedles: The Future of Drug Delivery equips readers with a comprehensive understanding of microneedles: from percutaneous absorption to microneedles production, characterization, applications in drug delivery and diagnosis, to practical perspectives on the development, manufacturing, regulatory issues, and commercialization of microneedles. This book is written by a single author and thus provides complex information in a simple, elegant, and cohesive style. The book is intended for graduate students, researchers, scientists, and engineers working in the pharmaceutical, medical, cosmeceutical, and biotechnology industry.
Download or read book Microneedles written by Kevin Ita and published by Academic Press. This book was released on 2022-02-06 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microneedles explores the design, fabrication and use of microneedles for drug and vaccine delivery. This book discusses the contemporary status of the field, describing several areas in detail, including the distinct types of microneedles (dissolving, solid, coted, hollow and hydrogel-forming). The anatomy of the eye is also described to facilitate an understanding of microneedle-assisted ocular drug delivery. Finally, the book provides a detailed discussion of microneedle use in the field of diagnostics, with a chapter dedicated to the mathematical modeling of microneedle-mediated drug delivery. As microneedles can be used by research scientists in academia and in industry, this book will be ideal for regulatory scientists and graduate students who find the topic relevant to their area of study. - Provides information for the design and fabrication of microneedles - Discusses choice of materials, fabrication protocol, sterilization protocol and characterization - Supplies the most up-to-date research on all aspects of microneedles
Book Synopsis MEMS-based Transdermal Drug Delivery by : Richa Mishra
Download or read book MEMS-based Transdermal Drug Delivery written by Richa Mishra and published by CRC Press. This book was released on 2023-12-11 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces transdermal drug delivery and the developments that have taken place in various transdermal drug delivery techniques including the system-level design approach of a novel miniaturized medical device to offer precise and painless drug delivery via a skin-based transdermal route. It discusses the microelectromechanical systems (MEMS)-based fabrication technique and the design, fabrication and characterization of different MEMS-based components like microneedles and micropumps. It further includes a MEMS-based component micropump with design, analysis, fabrication and characterization of the transdermal drug delivery device and challenges encountered in the design improvements. Features: Summarizes transdermal drug delivery systems especially with a focus on MEMS and microneedles, including theoretical concepts Emphasizes system integration by describing simulation and design techniques as well as experimental fabrication Discusses system-level integration for miniaturized therapeutic devices Includes working simulation models covering microneedles and micropump analysis Explores future direction in development of pertinent devices. The book is aimed at researchers, professionals, and graduate students in biomedical engineering, microelectronics, micro-electro-mechanical-systems, and drug delivery.
Book Synopsis Novel Delivery Systems for Transdermal and Intradermal Drug Delivery by : Ryan F. Donnelly
Download or read book Novel Delivery Systems for Transdermal and Intradermal Drug Delivery written by Ryan F. Donnelly and published by John Wiley & Sons. This book was released on 2015-09-28 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field and the various methods employed to produce delivery systems from different materials such as device design, construction and evaluation, so as to provide a sound background to the use of novel systems in enhanced delivery applications. Furthermore, it presents in-depth analyses of recent developments in this exponentially growing field, with a focus on microneedle arrays, needle-free injections, nanoparticulate systems and peptide-carrier-type systems. It also covers conventional physical enhancement strategies, such as tape-stripping, sonophoresis, iontophoresis, electroporation and thermal/suction/laser ablation Discussions about the penetration of the stratum corneum by the various novel strategies highlight the importance of the application method. Comprehensive and critical reviews of transdermal and intradermal delivery research using such systems focus on the outcomes of in vivoanimal and human studies. The book includes laboratory, clinical and commercial case studies featuring safety and patient acceptability studies carried out to date, and depicts a growing area for use of these novel systems is in intradermal vaccine delivery. The final chapters review recent patents in this field and describe the work ongoing in industry.
Book Synopsis Transdermal Drug Delivery by : Kevin Ita
Download or read book Transdermal Drug Delivery written by Kevin Ita and published by Academic Press. This book was released on 2020-06-12 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transdermal Drug Delivery: Concepts and Application provides comprehensive background knowledge and documents the most recent advances made in the field of transdermal drug delivery. It provides comprehensive and updated information regarding most technologies and formulation strategies used for transdermal drug delivery. There has been recent growth in the number of research articles, reviews, and other types of publications in the field of transdermal drug delivery. Research in this area is active both in the academic and industry settings. Ironically, only about 40 transdermal products with distinct active pharmaceutical ingredients are in the market indicating that more needs to be done to chronicle recent advances made in this area and to elucidate the mechanisms involved. This book will be helpful to researchers in the pharmaceutical and biotechnological industries as well as academics and graduate students working in the field of transdermal drug delivery and professionals working in the field of regulatory affairs focusing on topical and transdermal drug delivery systems. Researchers in the cosmetic and cosmeceutical industries, as well as those in chemical and biological engineering, will also find this book useful. - Captures the most recent advancements and challenges in the field of transdermal drug delivery - Covers both passive and active transdermal drug delivery strategies - Explores a selection of state-of-the-art transdermal drug delivery systems
Book Synopsis Optimisation of Microneedle Array Design for Microneedle Mediated Ionophoretic Transdermal Drug Delivery by : M. J. Garland
Download or read book Optimisation of Microneedle Array Design for Microneedle Mediated Ionophoretic Transdermal Drug Delivery written by M. J. Garland and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The present study was designed to identify the most suitable polymeric microneedle (MN) array design for use as an electrically responsive device capable of providing both sustained and on-demand percutaneous drug delivery both in vitro and in vivo. Soluble MN arrays loaded with a range of small to large molecules were fabricated from aqueous blends of 20% w/w poly(methyl vinyl ether eo maleic acid) (PMVEIMA). Novel hydrogel forming MN arrays were fabricated from aqueous blends containing 15% w/w PMVEIMA and 7.5% w/w poly(ethyleneglycol) (PEG, M; = 10 kDa). MN arrays were fabricated in a laser-engineered micro-moulding process. Hydrogel MN arrays were integrated with drug loaded reservoir patches. Whilst the combination of iontophoresis with both polymeric MN systems led to enhanced transdermal delivery of all drug molecules investigated in vitro, the electro- responsive nature of the hydrogel forming MN arrays enabled the sustained passive delivery and the electrically stimulated bolus delivery of the proteins insulin and bovine serum albumin in vivo. As such, this system may have great potential for the pulsatile transdermal delivery of therapeutic peptide/protein agents.
Book Synopsis Microneedles for Transdermal Drug Delivery by : Jaspreet Singh Kochhar
Download or read book Microneedles for Transdermal Drug Delivery written by Jaspreet Singh Kochhar and published by Springer. This book was released on 2019-07-04 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph covers a novel technology to deliver drugs and cosmetics through the skin in a minimally invasive manner. Microneedles – a bed of miniaturized needles is one of the most studied topics in delivering actives through the skin barrier. This book enables readers to understand the delivery of ingredients through the skin, describes a novel and simple method to fabricate microneedles containing a range of small and large molecular weight compounds, studies their physical properties as well as delivery through the skin layers. Readers will discover this book to be extremely beneficial to help them understand the state of the field of transdermal drug delivery, with extensive coverage including experimental data on basics of microneedle fabrication technology using photolithography, encapsulation of drugs within the polymeric matrix of microneedles and studying their release patternsin vitro and ex vivo . Academic researchers, pharmaceutical and cosmeceutical industry as well as students of skin science will find this account very useful in their pursuits. As microneedles grow and develop into a commercial reality with more actives being delivered and significant clinical research being put in, this account will hold well in providing basic principles and knowledge together with rigorous experimental data.
Book Synopsis Silk-based Drug Delivery Systems by : Elia Bari
Download or read book Silk-based Drug Delivery Systems written by Elia Bari and published by Royal Society of Chemistry. This book was released on 2020-10-07 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin.
Book Synopsis Microneedle Drug Delivery System by : Dr. Manish Kumar
Download or read book Microneedle Drug Delivery System written by Dr. Manish Kumar and published by Lulu.com. This book was released on 2018-04-18 with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a simple, concise view of the concepts and applications of microneedle drug delivery system. It is laid out in an easy-to-understand drug delivery through microneedle.
Book Synopsis Topical and Transdermal Drug Delivery by : Heather A. E. Benson
Download or read book Topical and Transdermal Drug Delivery written by Heather A. E. Benson and published by John Wiley & Sons. This book was released on 2012-02-03 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical drug development approaches presented by leading experts Designed to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and then demonstrates how these principles are put into practice in the design and development of new drug products. Drawing together and reviewing the latest research findings, the book focuses on practical, tested, and proven approaches that are backed by industry case studies and the authors' firsthand experience. Moreover, the book emphasizes the mechanistic information that is essential for successful drug product development. Topical and Transdermal Drug Delivery: Principles and Practice is divided into two parts: Part One, Current Science, Skin Permeation, and Enhancement Approaches, offers readers a fundamental understanding of the underlying science in the field. It describes the principles and techniques needed to successfully perform experimental approaches, covering such issues as skin permeation, enhancement, and assessment. Part Two, Topical and Transdermal Product Development, guides readers through the complete product development process from concept to approval, offering practical tips and cautions from experts in the field. This part also discusses regulations that are specific to the development of dermal drug products. The final chapter explores current and future trends, forecasting new development techniques and therapeutics. Throughout the book, the authors clearly set forth the basic science and experimental procedures, making it possible for researchers to design their own experimental approaches and accurately interpret their results. With contributions from experienced drug researchers, this text is highly recommended for all researchers involved in topical and transdermal product development who need to know both the state of the science and the standards of practice.
Book Synopsis Fundamentals and Applications of Controlled Release Drug Delivery by : Juergen Siepmann
Download or read book Fundamentals and Applications of Controlled Release Drug Delivery written by Juergen Siepmann and published by Springer Science & Business Media. This book was released on 2011-12-15 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book approaches the subject from a mechanistic perspective that pitches the language at a level that is understandable to those entering the field and who are not familiar with its common phrases or complex terms. It provides a simple encapsulation of concepts and expands on them. In each chapter the basic concept is explained as simply and clearly as possible without a great deal of detail, then in subsequent sections additional material, exceptions to the general rule, examples, etc., is introduced and built up. Such material was generously supplemented with diagrams; conceptually elegant line diagrams in two or three colors. The artwork was well thought out and able to condense the scientific principles into a novel and visually exciting form. The diagrams encourage browsing or draw the reader to salient points. In addition, the technique of highlighting key concepts in a separate box is used throughout each chapter.
Download or read book CMBEBIH 2019 written by Almir Badnjevic and published by Springer. This book was released on 2019-05-10 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume gathers the proceedings of the International Conference on Medical and Biological Engineering, which was held from 16 to 18 May 2019 in Banja Luka, Bosnia and Herzegovina. Focusing on the goal to ‘Share the Vision’, it highlights the latest findings, innovative solutions and emerging challenges in the field of Biomedical Engineering. The book covers a wide range of topics, including: biomedical signal processing, medical physics, biomedical imaging and radiation protection, biosensors and bioinstrumentation, bio-micro/nano technologies, biomaterials, biomechanics, robotics and minimally invasive surgery, and cardiovascular, respiratory and endocrine systems engineering. Further topics include bioinformatics and computational biology, clinical engineering and health technology assessment, health informatics, e-health and telemedicine, artificial intelligence and machine learning in healthcare, as well as pharmaceutical and genetic engineering. Given its scope, the book provides academic researchers, clinical researchers and professionals alike with a timely reference guide to measures for improving the quality of life and healthcare.
Book Synopsis Transdermal Delivery of Drugs by : Agis F. Kydonieus
Download or read book Transdermal Delivery of Drugs written by Agis F. Kydonieus and published by Springer. This book was released on 1987 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
