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Author : John L. Gill
Publisher : Iowa State Press
ISBN 13 :
Total Pages : 188 pages
Book Rating : 4.3/5 (91 download)
Download or read book Design and Analysis of Experiments in the Animal and Medical Sciences written by John L. Gill and published by Iowa State Press. This book was released on 1978 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gerald van Belle
Publisher : John Wiley & Sons
ISBN 13 : 0470127279
Total Pages : 256 pages
Book Rating : 4.4/5 (71 download)
Download or read book Design and Analysis of Experiments in the Health Sciences written by Gerald van Belle and published by John Wiley & Sons. This book was released on 2012-07-24 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: An accessible and practical approach to the design and analysis of experiments in the health sciences Design and Analysis of Experiments in the Health Sciences provides a balanced presentation of design and analysis issues relating to data in the health sciences and emphasizes new research areas, the crucial topic of clinical trials, and state-of-the- art applications. Advancing the idea that design drives analysis and analysis reveals the design, the book clearly explains how to apply design and analysis principles in animal, human, and laboratory experiments while illustrating topics with applications and examples from randomized clinical trials and the modern topic of microarrays. The authors outline the following five types of designs that form the basis of most experimental structures: Completely randomized designs Randomized block designs Factorial designs Multilevel experiments Repeated measures designs A related website features a wealth of data sets that are used throughout the book, allowing readers to work hands-on with the material. In addition, an extensive bibliography outlines additional resources for further study of the presented topics. Requiring only a basic background in statistics, Design and Analysis of Experiments in the Health Sciences is an excellent book for introductory courses on experimental design and analysis at the graduate level. The book also serves as a valuable resource for researchers in medicine, dentistry, nursing, epidemiology, statistical genetics, and public health.
Author : Simon T. Bate
Publisher : Cambridge University Press
ISBN 13 : 1107030781
Total Pages : 327 pages
Book Rating : 4.1/5 (7 download)
Download or read book The Design and Statistical Analysis of Animal Experiments written by Simon T. Bate and published by Cambridge University Press. This book was released on 2014-03-13 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will provide scientists with a better understanding of statistics, improving their decision-making and reducing animal use.
Author : John L. Gill
Publisher : Iowa State Press
ISBN 13 :
Total Pages : 432 pages
Book Rating : 4.3/5 (91 download)
Download or read book Design and Analysis of Experiments in the Animal and Medical Sciences written by John L. Gill and published by Iowa State Press. This book was released on 1978 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: A basic course in statistics as it applies to experiment design is provided in this 3-volume set. Statistical problems needing special attention are a factor in experiments involving human and animal subjects; therefore, scientists should have a grasp of quantitative concepts as they apply to experimental situations. Subjects discussed are basic principles and procedures, randomized design and variance analysis, single covariate in experimental design, monorthogonal and multivariate analysis, various forms of block design, repeated measurement and split-plot designs, and response surface designs. Appendices are contained in Volume 3, and include aglossary of symbols.
Author : Michael Festing
Publisher : SAGE Publications Limited
ISBN 13 : 9781473974630
Total Pages : 0 pages
Book Rating : 4.9/5 (746 download)
Download or read book The Design of Animal Experiments written by Michael Festing and published by SAGE Publications Limited. This book was released on 2016-12-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Where there is no alternative to the use of animals in biomedical research, it is important that experiments are well designed and correctly analysed in order to minimise pain and maximize the chance of getting scientifically valid results. Experiments that use too few animals may fail to pick up biologically important effects, while those who use them incorrectly or wastefully may get invalid results while subjecting the animals to unnecessary pain, distress or lasting harm. The Design of Animal Experiments is intended for all research scientists who use laboratory animals, with the aim of helping them to design their own experiments more effectively and/or to improve their ability to communicate with professional statisticians when necessary. It covers all randomised controlled experimental designs likely to be needed in laboratory animal research, with worked examples showing how they can be statistically analysed. It suggests the more widespread use of randomised block designs and shows how both males and females can be included in an experiment without the need to increase the total number of animals by using factorial designs. It also includes guidance on the choice of experimental animals. The book covers the learning outcomes of Module 10 and part (ii) of Module 11 of education and training under Directive 2010/63/EU.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 030921954X
Total Pages : 42 pages
Book Rating : 4.3/5 (92 download)
Download or read book Guidance for the Description of Animal Research in Scientific Publications written by National Research Council and published by National Academies Press. This book was released on 2011-09-16 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of research articles involving animal studies is central to many disciplines in science and biomedicine. Effective descriptions in such publications enable researchers to interpret the data, evaluate and replicate findings, and move the science forward. Analyses of published studies with research animals have demonstrated numerous deficiencies in the reporting of details in research methods for animal studies. Considerable variation in the amount of information required by scientific publications and reported by authors undermines this basic scientific principle and results in the unnecessary use of animals and other resources in failed efforts to reproduce study results. Guidance for the Description of Animal Research in Scientific Publications outlines the information that should be included in scientific papers regarding the animal studies to ensure that the study can be replicated. The report urges journal editors to actively promote effective and ethical research by encouraging the provision of sufficient information. Examples of this information include: conditions of housing and husbandry, genetic nomenclature, microbial status, detailed experimental manipulations, and handling and use of pharmaceuticals. Inclusion of this information will enable assessment and interpretation of research findings and advancement of knowledge based on reproducible results.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309038391
Total Pages : 113 pages
Book Rating : 4.3/5 (9 download)
Download or read book Use of Laboratory Animals in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.
Author : Basavarajaiah D. M.
Publisher : Springer Nature
ISBN 13 : 9811582106
Total Pages : 380 pages
Book Rating : 4.8/5 (115 download)
Download or read book Design of Experiments and Advanced Statistical Techniques in Clinical Research written by Basavarajaiah D. M. and published by Springer Nature. This book was released on 2020-11-05 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Statistical techniques are one of the basal evidence for clinical research, a pivotal in handling new clinical research and in evaluating and applying prior research. This book explores various choices of statistical tools and mechanisms, analyses of the associations among different clinical attributes. It uses advanced statistical methods to describe real clinical data sets, when the clinical processes being examined are still in the process. This book also discusses distinct methods for building predictive and probability distribution models in clinical situations and ways to assess the stability of these models and other quantitative conclusions drawn by realistic experimental data sets. Design of experiments and recent posthoc tests have been used in comparing treatment effects and precision of the experimentation. This book also facilitates clinicians towards understanding statistics and enabling them to follow and evaluate the real empirical studies (formulation of randomized control trial) that pledge insight evidence base for clinical practices. This book will be a useful resource for clinicians, postgraduates scholars in medicines, clinical research beginners and academicians to nurture high-level statistical tools with extensive scope.
Author : Andrew Knight
Publisher : Springer
ISBN 13 : 0230306411
Total Pages : 261 pages
Book Rating : 4.2/5 (33 download)
Download or read book The Costs and Benefits of Animal Experiments written by Andrew Knight and published by Springer. This book was released on 2011-05-27 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of recent scientific evidence examining the contributions of animal experimentation to human healthcare. The book also explores toxicity prediction, animal use during life and health sciences education, impacts on student attitudes toward animals, and the extent to which animals suffer in laboratories.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309164982
Total Pages : 238 pages
Book Rating : 4.3/5 (91 download)
Download or read book Critical Needs for Research in Veterinary Science written by National Research Council and published by National Academies Press. This book was released on 2005-10-18 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in veterinary science is critical for the health and well-being of animals, including humans. Food safety, emerging infectious diseases, the development of new therapies, and the possibility of bioterrorism are examples of issues addressed by veterinary science that have an impact on both human and animal health. However, there is a lack of scientists engaged in veterinary research. Too few veterinarians pursue research careers, and there is a shortage of facilities and funding for conducting research. This report identifies questions and issues that veterinary research can help to address, and discusses the scientific expertise and infrastructure needed to meet the most critical research needs. The report finds that there is an urgent need to provide adequate resources for investigators, training programs, and facilities involved in veterinary research.
Author : Kathrin Herrmann
Publisher :
ISBN 13 : 9789004356184
Total Pages : 0 pages
Book Rating : 4.3/5 (561 download)
Download or read book Animal Experimentation written by Kathrin Herrmann and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Experimentation: Working Towards a Paradigm Change critically appraises current animal use in science and discusses ways in which we can contribute to a paradigm change towards human-biology based approaches.
Author : Gerald Peter Quinn
Publisher : Cambridge University Press
ISBN 13 : 9780521009768
Total Pages : 560 pages
Book Rating : 4.0/5 (97 download)
Download or read book Experimental Design and Data Analysis for Biologists written by Gerald Peter Quinn and published by Cambridge University Press. This book was released on 2002-03-21 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regression, analysis of variance, correlation, graphical.
Author : John L. Gill
Publisher :
ISBN 13 : 9780813801100
Total Pages : 174 pages
Book Rating : 4.8/5 (11 download)
Download or read book Design and Analysis of Experiments in the Animal and Medical Sciences written by John L. Gill and published by . This book was released on 1978 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Hugh LaFollette
Publisher : Psychology Press
ISBN 13 : 9780415131131
Total Pages : 300 pages
Book Rating : 4.1/5 (311 download)
Download or read book Brute Science written by Hugh LaFollette and published by Psychology Press. This book was released on 1996 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Questions about the scientific and moral status of biomedical experimentation are hotly debated in the media and in professional circles. The outcome of this debate will shape future public health policy. The authors expose the weaknesses in both the standard defense and standard criticisms of animal experimentation. This thorough investigation of one of today's most fiercely debated questions yields some unexpected conclusions.
Author :
Publisher : John Wiley & Sons
ISBN 13 : 0471743844
Total Pages : 706 pages
Book Rating : 4.4/5 (717 download)
Download or read book Encyclopedia of Statistical Sciences, Volume 3 written by and published by John Wiley & Sons. This book was released on 2005-12-16 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt: ENCYCLOPEDIA OF STATISTICAL SCIENCES
Author : R. A. Bailey
Publisher : Cambridge University Press
ISBN 13 : 1139469916
Total Pages : 345 pages
Book Rating : 4.1/5 (394 download)
Download or read book Design of Comparative Experiments written by R. A. Bailey and published by Cambridge University Press. This book was released on 2008-04-17 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book should be on the shelf of every practising statistician who designs experiments. Good design considers units and treatments first, and then allocates treatments to units. It does not choose from a menu of named designs. This approach requires a notation for units that does not depend on the treatments applied. Most structure on the set of observational units, or on the set of treatments, can be defined by factors. This book develops a coherent framework for thinking about factors and their relationships, including the use of Hasse diagrams. These are used to elucidate structure, calculate degrees of freedom and allocate treatment subspaces to appropriate strata. Based on a one-term course the author has taught since 1989, the book is ideal for advanced undergraduate and beginning graduate courses. Examples, exercises and discussion questions are drawn from a wide range of real applications: from drug development, to agriculture, to manufacturing.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309073162
Total Pages : 261 pages
Book Rating : 4.3/5 (9 download)
Download or read book Evaluating Chemical and Other Agent Exposures for Reproductive and Developmental Toxicity written by National Research Council and published by National Academies Press. This book was released on 2001-04-13 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The United States Navy has been concerned for some time with protecting its military and civilian personnel from reproductive and developmental hazards in the workplace. As part of its efforts to reduce or eliminate exposure of Naval personnel and their families to reproductive and developmental toxicants, the Navy requested that the National Research Council (NRC) recommend an approach that can be used to evaluate chemicals and physical agents for their potential to cause reproductive and developmental toxicity. The NRC assigned this project to the Committee on Toxicology, which convened the Subcommittee on Reproductive and Developmental Toxicology, to prepare this report. In this report, the subcommittee recommends an approach for evaluating agents for potential reproductive and developmental toxicity and demonstrates how that approach can be used by the Navy. This report has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise, in accordance with procedures approved by the NRC's Report Review Committee. The purpose of this independent review is to provide candid and critical comments that will assist the institution in making its published report as sound as possible and to ensure that the report meets institutional standards for objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the deliberative process. We wish to thank the following individuals for their review of this report: James Chen (National Center for Toxicological Research), George Daston (Procter and Gamble Company), Jerry Heindel (National Institute of Environmental Health Sciences), Grace Lemasters (University of Cincinnati), and John Young (National Center for Toxicological Research).
