Deprenyl Past And Future

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Deprenyl — Past and Future

Author : Wilfried Kuhn
Publisher : Springer Science & Business Media
ISBN 13 : 3709174945
Total Pages : 191 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Deprenyl — Past and Future by : Wilfried Kuhn

Download or read book Deprenyl — Past and Future written by Wilfried Kuhn and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert clinicians and basic scientists with a special interest in Parkinson's disease review the current state of science and clinical therapeutics of the disease. Therefore these articles represent an authorative review of the current state of knowledge regarding preclinical course and symptomatology, subtypes with their impact on the pathology, genetic alterations, novel mechanisms of neuronal cell death, diagnostic tools and old and novel therapeutic approaches with respect to neuroprotection and neuroregeneration in Parkinson's disease. Particular emphasis has been placed on a novel antiparkinsonian drug called budipine with various modes of action also influencing altered non dopaminergic systems in Parkinson's disease. It is evident, that many questions on the cause, course and treatment of Parkinson's disease are still unanswered and therefore the ideal way to treat a parkinsonian patient remains to be defined.

How Selegiline ((-)-Deprenyl) Slows Brain Aging

Author : Joseph Knoll
Publisher : Bentham Science Publishers
ISBN 13 : 1608054705
Total Pages : 161 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis How Selegiline ((-)-Deprenyl) Slows Brain Aging by : Joseph Knoll

Download or read book How Selegiline ((-)-Deprenyl) Slows Brain Aging written by Joseph Knoll and published by Bentham Science Publishers. This book was released on 2012-10-12 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book is a reference on Selegiline ((-)-Deprenyl) effects on the brain. Selegiline, described in thousands of research papers, is registered in over 60 countries. At present, more than one hundred preparations containing selegiline circulate in the global market under different brand names. They are widely used in the treatment of Parkinson's disease, Alzheimer's disease, major depression and as a geroprotective / anti-aging drug. ((-)-Deprenyl) selegiline, the first selective inhibitor of B-type MAO which, in contrast to the known MAO inhibitors, did not potentiate the effect of tyramine but inhibited it. the compound could be combined with levodopa in Parkinson's disease without signs of hypertensive reactions. the DATATOP study in the USA revealed that (-)-deprenyl delayed the onset of disability associated with early, otherwise untreated Parkinson's disease. the age-related decay of the supply of the brain with phenylethylamine (PEA), due to the progressive increase of MAO-B activity in the aging brain, and dopamine, due to the better than average decline of the dopaminergic neuronal activity during the postdevelopmental phase of life, are irresistible biochemical lesions of aging. the speed of deterioration of behavioral performances with the passing of time and longevity depends significantly on the pace of the worsening of these lesions. (-)-Deprenyl, increasing the supply of the brain with PEA and dopamine, counteracts this aging process. Maintenance of male rats from sexual maturity until death on ((-)-deprenyl) delays the age-related loss of the capacity to ejaculate, slows the age-related decline of learning ability and prolongs life. In humans, maintenance from sexual maturity on (-)-deprenyl (1 mg daily) is, for the time being, the most promising prophylactic treatment to fight against the age-related decay of behavioral performances, prolonging life, and preventing or delaying the onset of age-related neurodegenerative diseases such as Parkinson's and Alzheimer's. This e-book is a useful reference for graduate medical students, academic researchers in the field of neuropsychopharmacology, neurophysiology and gerontology and professional research groups in commercial organizations manufacturing selegiline preparations.

Antidepressants: Past, Present and Future

Author : Sheldon H. Preskorn
Publisher : Springer Science & Business Media
ISBN 13 : 3642185002
Total Pages : 613 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Antidepressants: Past, Present and Future by : Sheldon H. Preskorn

Download or read book Antidepressants: Past, Present and Future written by Sheldon H. Preskorn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of the current status of antidepressants - how we arrived at this point in their evolution and where we are going in both the near and the long term. It employs both a scientific and historical approach to accomplish these goals. This volume is intended for practitioners who use antidepressants on a daily basis in their practice as well as for the student and researcher. Each will find that it provides a comprehensive and logical approach to this important group of medications. This book is being published as we mark the end of the first 50 years of the modern antidepressant era.

Towards New Therapies for Parkinson's Disease

Author : David Finkelstein
Publisher : IntechOpen
ISBN 13 : 9789533074634
Total Pages : 410 pages
Book Rating : 4.0/5 (746 download)

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Book Synopsis Towards New Therapies for Parkinson's Disease by : David Finkelstein

Download or read book Towards New Therapies for Parkinson's Disease written by David Finkelstein and published by IntechOpen. This book was released on 2011-11-02 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parkinson's disease (PD) is characterised clinically by various non-motor and progressive motor symptoms, pathologically by loss of dopamine producing cells and intraneuronal cytoplasmic inclusions composed primarily of ?-synuclein. By the time a patient first presents with symptoms of Parkinson's disease at the clinic, a significant proportion of the cells in the substantia nigra have already been destroyed. This degeneration progresses despite the current therapies until the cell loss is so great that the quality of normal life is compromised. The dopamine precursor levodopa is the most valuable drug currently available for the treatment of PD. However for most PD patients, the optimal clinical benefit from levodopa decreases around five to six years of treatment. The aim of the chapters of this book is to work towards an understanding in the mechanisms of degeneration and to develop disease modifying therapies.

Essential Psychopharmacology: the Prescriber's Guide

Author : Stephen M. Stahl
Publisher : Cambridge University Press
ISBN 13 : 9780521011693
Total Pages : 592 pages
Book Rating : 4.0/5 (116 download)

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Book Synopsis Essential Psychopharmacology: the Prescriber's Guide by : Stephen M. Stahl

Download or read book Essential Psychopharmacology: the Prescriber's Guide written by Stephen M. Stahl and published by Cambridge University Press. This book was released on 2005 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: In full color throughout, this pragmatic guide for prescribing clinicians complements the conceptual approach of the best-selling Essential Psychopharmacology. Covering over 100 psychotropic drugs, each with four or more pages, Stephen Stahl gives all the information a prescribing clinician needs to treat patients effectively. For each drug the information comes in five brief, clear categories: general therapeutics, dosing and use, side effects, special populations, and pearls. Target icons appear next to key categories for each drug so that the prescriber can go easily and instantly to the information needed. There are several indices, one consisting of a comprehensive list of both generic and proprietary names for all the drugs featured, one categorizing the generic drugs by use, and one listing the drugs by class.

Parkinson's Disease

Author :
Publisher : Academic Press
ISBN 13 : 0128098503
Total Pages : 542 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Parkinson's Disease by :

Download or read book Parkinson's Disease written by and published by Academic Press. This book was released on 2017-05-26 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parkinson's Disease, Volume 132 addresses new developments in the F33 study of this disease, highlighting how the lives of people with Parkinson’s have undergone dramatic changes in the last decade. New to this edition are chapters on the Hallmarks of clinical aspects PD throughout centuries, The motor syndrome of Parkinson disease, The non-motor features of Parkinson’s disease, The New Diagnostic Criteria for Parkinson's disease, Advances in the Clinical Differential diagnosis, Clinical assessments in PD : Scales and monitoring, Biomarkers of Parkinson’s disease: an Introduction, and the Genetics of Parkinson’s Disease: Genotype-Phenotype Correlations. The topics discussed in this comprehensive series provide a clearer understanding of the prodromal stage, genetics, strategies, routes of treatment, and development of non-dopaminergic therapies in Parkinson's Disease, both medical and surgical. Contains cutting-edge developments in the field Presents both motor and non-motor coverage

The Future of Aging

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9048139988
Total Pages : 866 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis The Future of Aging by :

Download or read book The Future of Aging written by and published by Springer Science & Business Media. This book was released on 2010-08-17 with total page 866 pages. Available in PDF, EPUB and Kindle. Book excerpt: Just as the health costs of aging threaten to bankrupt developed countries, this book makes the scientific case that a biological "bailout" could be on the way, and that human aging can be different in the future than it is today. Here 40 authors argue how our improving understanding of the biology of aging and selected technologies should enable the successful use of many different and complementary methods for ameliorating aging, and why such interventions are appropriate based on our current historical, anthropological, philosophical, ethical, evolutionary, and biological context. Challenging concepts are presented together with in-depth reviews and paradigm-breaking proposals that collectively illustrate the potential for changing aging as never before. The proposals extend from today to a future many decades from now in which the control of aging may become effectively complete. Examples include sirtuin-modulating pills, new concepts for attacking cardiovascular disease and cancer, mitochondrial rejuvenation, stem cell therapies and regeneration, tissue reconstruction, telomere maintenance, prevention of immunosenescence, extracellular rejuvenation, artificial DNA repair, and full deployment of nanotechnology. The Future of Aging will make you think about aging differently and is a challenge to all of us to open our eyes to the future therapeutic potential of biogerontology.

How to Use Herbs, Nutrients & Yoga in Mental Health Care

Author : Richard P. Brown
Publisher : W. W. Norton & Company
ISBN 13 : 9780393705256
Total Pages : 476 pages
Book Rating : 4.7/5 (52 download)

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Book Synopsis How to Use Herbs, Nutrients & Yoga in Mental Health Care by : Richard P. Brown

Download or read book How to Use Herbs, Nutrients & Yoga in Mental Health Care written by Richard P. Brown and published by W. W. Norton & Company. This book was released on 2009 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: All you need to know about herbs, nutrients, and yoga for enhancing mental health.

Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 1716 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2001-04 with total page 1716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Parkinson's Disease: Current and Future Therapeutics and Clinical Trials

Author : Néstor Gálvez-Jiménez
Publisher : Cambridge University Press
ISBN 13 : 1107053862
Total Pages : 385 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Parkinson's Disease: Current and Future Therapeutics and Clinical Trials by : Néstor Gálvez-Jiménez

Download or read book Parkinson's Disease: Current and Future Therapeutics and Clinical Trials written by Néstor Gálvez-Jiménez and published by Cambridge University Press. This book was released on 2016-03-24 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book emphasizes treatment options for Parkinson's disease, providing the necessary clinical and scientific basis for the foundations of solid therapeutics.

Cumulated Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 1824 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1997 with total page 1824 pages. Available in PDF, EPUB and Kindle. Book excerpt:

An Essay on the Shaking Palsy

Author : James Parkinson
Publisher :
ISBN 13 :
Total Pages : 86 pages
Book Rating : 4.A/5 ( download)

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Book Synopsis An Essay on the Shaking Palsy by : James Parkinson

Download or read book An Essay on the Shaking Palsy written by James Parkinson and published by . This book was released on 1817 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Critical Reviews Oxidative Stress And Aging: Advances In Basic Science, Diagnostics And Intervention (In 2 Vols)

Author : Richard G Cutler
Publisher : World Scientific
ISBN 13 : 9814490946
Total Pages : 1621 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Critical Reviews Oxidative Stress And Aging: Advances In Basic Science, Diagnostics And Intervention (In 2 Vols) by : Richard G Cutler

Download or read book Critical Reviews Oxidative Stress And Aging: Advances In Basic Science, Diagnostics And Intervention (In 2 Vols) written by Richard G Cutler and published by World Scientific. This book was released on 2002-10-28 with total page 1621 pages. Available in PDF, EPUB and Kindle. Book excerpt: This innovative and comprehensive reference book provides the most up-to-date information pertaining to the translational research field of oxidative stress and aging. The book focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases with the goal being the development of new and novel methods in treating the human aging processes. The book charts the course of this new and rapidly emerging field of Oxidative Stress Diagnostics and Therapeutics that will have a significant impact on the future economics, science and practice of medicine. Over 100 of the leading experts in this field whose specialty includes biogerontology, geriatric medicine, free radical chemistry and biology, oncology, cardiology, neurobiology, dermatology, pharmacology, nutrition, and molecular medicine, have contributed information to this book. This reference book is an essential reading material to a broad range of individuals including researchers, physicians, corporate industry leaders, graduate and medical school students, as well as the many health conscious individuals who wish to know more about the emerging field of oxidative stress and aging with an emphasis on diagnostics and intervention.

Critical Reviews of Oxidative Stress and Aging

Author : Richard G. Cutler
Publisher : World Scientific
ISBN 13 : 9789812389978
Total Pages : 758 pages
Book Rating : 4.3/5 (899 download)

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Book Synopsis Critical Reviews of Oxidative Stress and Aging by : Richard G. Cutler

Download or read book Critical Reviews of Oxidative Stress and Aging written by Richard G. Cutler and published by World Scientific. This book was released on 2003 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume reference examines the translational research field of oxidative stress and ageing. It focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases, with the goal of developing new methods for treating the human ageing processes.

Advances in Research on Neurodegeneration

Author :
Publisher :
ISBN 13 :
Total Pages : 362 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Advances in Research on Neurodegeneration by :

Download or read book Advances in Research on Neurodegeneration written by and published by . This book was released on 1997 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Atlas of Psychiatric Pharmacotherapy

Author : Roni Shiloh
Publisher : CRC Press
ISBN 13 : 1435626230
Total Pages : 288 pages
Book Rating : 4.4/5 (356 download)

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Book Synopsis Atlas of Psychiatric Pharmacotherapy by : Roni Shiloh

Download or read book Atlas of Psychiatric Pharmacotherapy written by Roni Shiloh and published by CRC Press. This book was released on 2006-01-13 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this exceptional book provides a comprehensive understanding of the mechanisms of action involved in psychiatric pharmacotherapy. Using imaginative colourful double-page spreads, this exceptional book presents state-of-the-art information on all the basic principles of psychiatric pharmacotherapy, abused substances, drug inter

Past, Present And Future Of Psychiatry - Ix World Congress Of Psychiatry (In 2 Volumes)

Author : Allan Beigel
Publisher : World Scientific
ISBN 13 : 9814663328
Total Pages : 1549 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis Past, Present And Future Of Psychiatry - Ix World Congress Of Psychiatry (In 2 Volumes) by : Allan Beigel

Download or read book Past, Present And Future Of Psychiatry - Ix World Congress Of Psychiatry (In 2 Volumes) written by Allan Beigel and published by World Scientific. This book was released on 1994-09-27 with total page 1549 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the highlights of the IX World Congress of Psychiatry. The congress was a major event with the participation of over 6000 scientists from all over the world with the scientific program covering all aspects of contemporary psychiatry. The 200 papers selected for this volume provide an insight into recent advances in psychiatry. They discuss a wide spectrum of subjects ranging from the diagnosis and treatment of mental illnesses to critical issues affecting the future of mental health care throughout the world. Authors include leading psychiatric clinicians and researchers throughout the world as well as international mental health policy makers.