D1:D2 Dopamine Receptor Interactions

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Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis D1:D2 Dopamine Receptor Interactions by : John L. Waddington

Download or read book D1:D2 Dopamine Receptor Interactions written by John L. Waddington and published by . This book was released on 1993 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents up-to-date comprehensive reviews of neuroscience research and theory on the fundamental interactions between the D1 and D2 dopamine receptor subtypes at numerous levels of investigation-from molecular biology and neuroanatomy, through electrophysiology, to the psychopharmacology of multiple forms of behavior, putative clinical significance, and therapeutic potential. This volume seeks to stand as a reference source on the evolution of the concept of D1: D2 interactions, on their substrates and psychopharmacological roles and, in such a continually evolving field, to look to the future. The Neuroscience Perspectives series aims to provide an all-round view of a current topic of great interest in neuroscience from the biochemical, pharmacological, and physiological standpoints together with the potential therapeutic applications. * SPECIAL FEATURES: * This is the ninth in Neuroscience Perspectives. * A Volume in Neuroscience Perspectives following series aim of providing all-round view of a current topic of great interest in Neuroscience from the biochemical, pharmacological and physiological standpoints together with the potential therapeutic applications. * The brain dopamine receptor has been the subject of intense interest for the past ten years owing to its involvement in motor and psychotic conditions. It is the target for the development of potential new drugs for eg. Schizophrenia and Parkinsons Diseases. Two subtypes of receptor have been found (D1 and D2). This book, edited by a respected expert in the field, examines the history of the topic, biochemistry, molecular biology and mode of interaction of the subtypes, and the therapeutic potential of the scientific discoveries, in the format of Neuroscience Perspectives. An issue of Nature in October 1990 led with the reported discovery of a D3 receptor. The implications of this for future research will be discussed in the final chapter.

Receptor-Receptor Interactions

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Publisher : Springer Science & Business Media
ISBN 13 : 1468454153
Total Pages : 577 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Receptor-Receptor Interactions by : Kjell Fuxe

Download or read book Receptor-Receptor Interactions written by Kjell Fuxe and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dopamine in the CNS I

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Publisher : Springer Science & Business Media
ISBN 13 : 3642560512
Total Pages : 355 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Dopamine in the CNS I by : Gaetano Di Chiara

Download or read book Dopamine in the CNS I written by Gaetano Di Chiara and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts

Kinetic Aspects of Dopamine D2 Receptor Interactions with Specific Ligands

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Publisher :
ISBN 13 : 9789985565346
Total Pages : 81 pages
Book Rating : 4.5/5 (653 download)

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Book Synopsis Kinetic Aspects of Dopamine D2 Receptor Interactions with Specific Ligands by : Martin Lepiku

Download or read book Kinetic Aspects of Dopamine D2 Receptor Interactions with Specific Ligands written by Martin Lepiku and published by . This book was released on 2000 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biology of the NMDA Receptor

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Publisher : CRC Press
ISBN 13 : 142004415X
Total Pages : 368 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Biology of the NMDA Receptor by : Antonius M. VanDongen

Download or read book Biology of the NMDA Receptor written by Antonius M. VanDongen and published by CRC Press. This book was released on 2008-10-29 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written

Central D1 Dopamine Receptors

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Publisher : Springer
ISBN 13 : 1489927239
Total Pages : 184 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Central D1 Dopamine Receptors by : M. J. Goldstein

Download or read book Central D1 Dopamine Receptors written by M. J. Goldstein and published by Springer. This book was released on 2013-11-21 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of a selective D1 dopamine (DA) receptor antagonist SCH 23390 stimulated a number of studies on the functions mediated by central DA receptor subtypes. It was generally assumed that the central D1 DA receptor isa molecular entity whose function awaits further discovery. The papers presented in this volume clearly show that this is no longer the case and that D1 DA receptors have many behavioral fuctions which might be altered in pathological states. A number of papers have recognized the interdependence of the regulatory functions of the D1 DA receptors with D2 and other receptor proteins, and vice versa. The biochemical, pharmacological and morphological characterization of the D1 and D2 DA receptor binding proteins, as well as of DARPP-32, illustrates the complex interactions between various macromolecules. Procedures described for the purification of the D1 and D2 DA receptor subtypes are fundamental for future studies on the mechanisms involved in the coupling of the receptor proteins with signal transducing systems. Several studies in this volume show that D1 DA receptors have behavioral functions and that they are often similar to the responses mediated by D2 DA receptors, but in some instances reflect divergent neuronal activity of both systems. The knowledge of the physiology and biochemistry of the central DA receptor subtypes could lead to the development of a new generation of drugs which ameliorate some mental and neurological dysfunctions without producing severe undesirable side effects.

The Dopamine Receptors

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Publisher : Springer Science & Business Media
ISBN 13 : 1603273336
Total Pages : 650 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis The Dopamine Receptors by : Kim Neve

Download or read book The Dopamine Receptors written by Kim Neve and published by Springer Science & Business Media. This book was released on 2009-12-01 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: As sites of action for drugs used to treat schizophrenia and Parkinson’s disease, dopamine receptors are among the most validated drug targets for neuropsychiatric disorders. Dopamine receptors are also drug targets or potential targets for other disorders such as substance abuse, depression, Tourette’s syndrome, and attention deficit hyperactivity disorder. Updated from the successful first edition, "The Dopamine Receptors" serves as a reference work on dopamine receptors while also highlighting the areas of research that are most active today. To achieve this goal, authors have written chapters that set a broad area of research in its historical context, rather than focusing on the research output of their own laboratories.

Tourette Syndrome

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Publisher : Oxford University Press
ISBN 13 : 0197543219
Total Pages : 577 pages
Book Rating : 4.1/5 (975 download)

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Book Synopsis Tourette Syndrome by : Davide Martino

Download or read book Tourette Syndrome written by Davide Martino and published by Oxford University Press. This book was released on 2022 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tourette syndrome (TS) has become increasingly recognised within society and has gained scientific interest worldwide. Knowledge of its clinical presentation, mechanisms of disease, and available treatment approaches has increased remarkably over the last two decades. Likewise, the way clinicians, teachers, social care workers, and families face the problems manifested by patients with TS is rapidly evolving. Tourette Syndrome, edited by Davide Martino and James F. Leckman, offers a unique opportunity to capture this knowledge advance through a comprehensive and up-to-date overview. Tourette Syndrome covers all the main aspects related to TS, analyzing its complex clinical presentation, the novel viewpoints of causes and mechanisms, state-of-the-art assessment techniques, and the diversity of treatment options. Multidisciplinarity is the main asset of this volume, which represents a source of consultation for a wide audience of professionals, integrated with video tutorials related to particularly complex areas of patient management. Medical and PhD students, as well as post-doctoral scientists, will be able to use the volume as a valuable learning source.

The Dopamine Receptors

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Publisher : Springer Science & Business Media
ISBN 13 : 147572635X
Total Pages : 555 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis The Dopamine Receptors by : Kim Neve

Download or read book The Dopamine Receptors written by Kim Neve and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seven years after the cloning of the rat dopamine D receptor, and four 2 years after the cloning of the last mammalian dopamine receptor identified to date, this seems to be an excellent time to put together the present The Dopamine Receptors volume ofthis series, The Receptors. There has been time for considerable characterization of the novel receptor subtypes, and new, exciting lines of research from the molecular to the behavioral levels are taking shape. We asked the contributors to The Dopamine Receptors to follow the superb example set by the previous volumes in this series by writing compre hensive, historical reviews that will comprise an essential resource for nonspe cialists and newcomers to the dopamine receptor field, while at the same time providing up-to-date summaries of the most active areas of research. It is difficult these days to write about receptors without addressing the issue of receptor nomenclature. For dopamine receptors, valid arguments can be made for a system in which the subtypes are classified as belonging to the Dl or D2 classes, with letters assigned in the order of cloning (D A, D , D A, 1 18 2 D , Dc). We decided, however, that common usage counts for something, and 28 2 chose to use D , D , and D for the D2-like receptors because these names are 2 3 4 nearly unanimously used in the literature.

A Synopsis of Parkinson's Disease

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Publisher : BoD – Books on Demand
ISBN 13 : 9535112295
Total Pages : 233 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis A Synopsis of Parkinson's Disease by : Md, Frcpc, Frcp (hon), Abdul Qayyum Rana

Download or read book A Synopsis of Parkinson's Disease written by Md, Frcpc, Frcp (hon), Abdul Qayyum Rana and published by BoD – Books on Demand. This book was released on 2014-03-26 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parkinsons disease is a disabling neurological condition with both motor and non-motor symptoms for which no cure is available at this stage. This book is unique in covering the most important topics related to Parkinsons disease. Current research and updates about some non-motor symptoms, as well as surgical treatment of Parkinsons disease, in addition to the long term complications of pharmacological treatments have been presented. This book can be used by physicians, researchers and neuroscientists who want to learn new information about these topics related to Parkinsons disease. Authors of the individual chapters are well known in their fields and the book has been edited by a world renowned Parkinsons disease expert.

Encyclopedic Reference of Molecular Pharmacology

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Publisher :
ISBN 13 :
Total Pages : 1152 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Encyclopedic Reference of Molecular Pharmacology by : Stefan Offermanns

Download or read book Encyclopedic Reference of Molecular Pharmacology written by Stefan Offermanns and published by . This book was released on 2004 with total page 1152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents current information on the molecular mechanisms of drug action. Provides 159 essays describing groups of drugs and drug targets. Several essays deal with general principles of pharmacology, such as drug tolerance, drug addiction, or drug metabolism.

Encyclopedia of Movement Disorders

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Publisher : Academic Press
ISBN 13 : 012374105X
Total Pages : 1633 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Encyclopedia of Movement Disorders by :

Download or read book Encyclopedia of Movement Disorders written by and published by Academic Press. This book was released on 2010-02-26 with total page 1633 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Movement Disorders is a comprehensive reference work on movement disorders, encompassing a wide variety of topics in neurology, neurosurgery, psychiatry and pharmacology. This compilation will feature more than 300 focused entries, including sections on different disease states, pathophysiology, epidemiology, genetics, clinical presentation, diagnostic tools, as well as discussions on relevant basic science topics. This Encyclopedia is an essential addition to any collection, written to be accessible for both the clinical and non-clinical reader. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in the laboratory to the clinical features, pathophysiology and treatment of movement disorders. The Encyclopedia targets a broad readership, ranging from students to general physicians, basic scientists and Movement Disorder specialists. Published both in print and via Elsevier’s online platform of Science Direct, this Encyclopedia will have the enhanced option of integrating traditional print with online multimedia. Connects experimental findings made in the laboratory to the clinical features, pathophysiology, and treatment of movement disorders Encompasses a wide variety of topics in neurology neurosurgery, psychiatry, and pharmacology Written for a broad readership ranging from students to general physicians, basic scientists, and movement disorder specialists

Dopamine Handbook

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Publisher :
ISBN 13 : 0195373030
Total Pages : 632 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Dopamine Handbook by : Leslie L. Iversen

Download or read book Dopamine Handbook written by Leslie L. Iversen and published by . This book was released on 2010 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of dopamine in 1957-1958 was one of the seminal events in the development of modern neuroscience, and has been extremely important for the development of modern therapies of neurological and psychiatric disorders. Dopamine has a fundamental role in almost all aspects of behavior: from motor control to mood regulation, cognition and addiction and reward, and dopamine research has been unique within the neurosciences in the way it has bridged basic science and clinical practice. Over the decades research into the role of dopamine in health and disease has been in the forefront of modern neuroscience. The Dopamine Handbook is the first single-volume publication to capture current progress and excitement in this dynamic research field.

Diagnosis and Management in Parkinson's Disease

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Publisher : Academic Press
ISBN 13 : 0128159472
Total Pages : 784 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Diagnosis and Management in Parkinson's Disease by : Colin R Martin

Download or read book Diagnosis and Management in Parkinson's Disease written by Colin R Martin and published by Academic Press. This book was released on 2020-08-13 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosis and Management in Parkinson's Disease: The Neuroscience of Parkinson’s, Volume 1 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. It fills a much-needed gap as a "one-stop" synopsis of everything concerning the neurology and neuroscience related to Parkinson’s disease, from chemicals and cells to individuals. The book is an invaluable resource for neuroscientists, neurologists, and anyone in the field. Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations Serves as a "one-stop" source for everything you need to know about Parkinson’s disease

Medical Biochemistry

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Publisher : Academic Press
ISBN 13 : 0120954400
Total Pages : 1068 pages
Book Rating : 4.1/5 (29 download)

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Book Synopsis Medical Biochemistry by : N. V. Bhagavan

Download or read book Medical Biochemistry written by N. V. Bhagavan and published by Academic Press. This book was released on 2002 with total page 1068 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents the fundamentals of biochemistry and related topics for all those pursuing medical or other health-related fields such as clinical chemistry, medical technology, or pharmacology.

Handbook of the Behavioral Neurobiology of Serotonin

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Publisher : Academic Press
ISBN 13 : 0080878172
Total Pages : 849 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Handbook of the Behavioral Neurobiology of Serotonin by : Christian P. Muller

Download or read book Handbook of the Behavioral Neurobiology of Serotonin written by Christian P. Muller and published by Academic Press. This book was released on 2009-12-30 with total page 849 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the major excitatory neurotransmitter, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood. Alterations in the serotonergic system, induced by e.g. learning or pathological processes, underlie behavioural plasticity and changes in mood, which can finally results in abnormal behaviour and psychiatric conditions. Not surprisingly, the serotonergic system and its functional components appear to be targets for a multitude of pharmacological treatments - examples of very successful drugs targeting the serotoninergic system include Prozac and Zoloft. The last decades of research have not only fundamentally expanded our view on serotonin but also revealed in much more detail an astonishing complexity of this system, which comprises a multitude of receptors and signalling pathways. A detailed view on its role in basal, but also complex, behaviours emerged, and, was presented in a number of single review articles. Although much is known now, the serotonergic system is still a fast growing field of research contributing to our present understanding of the brains function during normal and disturbed behaviour. This handbook aims towards a detailed and comprehensive overview over the many facets of behavioural serotonin research. As such, it will provide the most up to date and thorough reading concerning the serotonergic systems control of behaviour and mood in animals and humans. The goal is to create a systematic overview and first hand reference that can be used by students and scholars alike in the fields of genetics, anatomy, pharmacology, physiology, behavioural neuroscience, pathology, and psychiatry. The chapters in this book will be written by leading scientists in this field. Most of them have already written excellent reviews in their field of expertise. The book is divided in 4 sections. After an historical introduction, illustrating the growth of ideas about serotonin function in behaviour of the last forty years, section A will focus on the functional anatomy of the serotonergic system. Section B provides a review of the neurophysiology of the serotonergic system and its single components. In section C the involvement of serotonin in behavioural organization will be discussed in great detail, while section D deals with the role of serotonin in behavioural pathologies and psychiatric disorders. The first handbook broadly discussing the behavioral neurobiology of the serotonorgic transmitter system Co-edited by one of the pioneers and opinion leaders of the past decades, Barry Jacobs (Princeton), with an international list (10 countries) of highly regarded contributors providing over 50 chapters, and including the leaders in the field in number of articles and citations: K. P. Lesch, T. Sharp, A. Caspi, P. Blier, G.K. Aghajanian, E. C. Azmitia, and others The only integrated and complete resource on the market containing the best information integrating international research, providing a global perspective to an international community Of great value not only for researchers and experts, but also for students and clinicians as a background reference

Drug Induced Movement Disorders

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Publisher : John Wiley & Sons
ISBN 13 : 140513755X
Total Pages : 480 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Drug Induced Movement Disorders by : Stewart Factor

Download or read book Drug Induced Movement Disorders written by Stewart Factor and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second revised edition of this text will update and present current state of the art clinical approaches to this subject. This book will continue to be the source text of information on drug-induced movement disorders authored and edited by the pioneers in the field. It will be an invaluable addition to the library of any neurologist.