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Cytoskeletal Dynamics And Mechanics In Cell Growth Division Differentiation And Aging
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Book Synopsis Cytoskeletal Dynamics and Mechanics in Cell Growth, Division, Differentiation and Aging by : Ting Gang Chew
Download or read book Cytoskeletal Dynamics and Mechanics in Cell Growth, Division, Differentiation and Aging written by Ting Gang Chew and published by Frontiers Media SA. This book was released on 2022-01-25 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cytoskeleton by : Jose C. Jimenez-Lopez
Download or read book Cytoskeleton written by Jose C. Jimenez-Lopez and published by BoD – Books on Demand. This book was released on 2017-05-17 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cytoskeleton is a highly dynamic intracellular platform constituted by a three-dimensional network of proteins responsible for key cellular roles as structure and shape, cell growth and development, and offering to the cell with "motility" that being the ability of the entire cell to move and for material to be moved within the cell in a regulated fashion (vesicle trafficking). The present edition of Cytoskeleton provides new insights into the structure-functional features, dynamics, and cytoskeleton's relationship to diseases. The authors' contribution in this book will be of substantial importance to a wide audience such as clinicians, researches, educators, and students interested in getting updated knowledge about molecular basis of cytoskeleton, such as regulation of cell vital processes by actin-binding proteins as cell morphogenesis, motility, their implications in cell signaling, as well as strategies for clinical trial and alternative therapies based in multitargeting molecules to tackle diseases, that is, cancer.
Book Synopsis The Cytoskeleton in Health and Disease by : Heide Schatten
Download or read book The Cytoskeleton in Health and Disease written by Heide Schatten and published by Springer. This book was released on 2015-08-21 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume addresses the structural and functional roles of the cytoskeleton and its dysfunctions which often lead to disease. It provides thorough discussion of microtubules, microfilaments, intermediate filaments, and cytoskeletal functions and dysfunctions in different organ systems. Comprehensive yet concise. The Cytoskeleton In Health And Disease presents cutting-edge discoveries balanced with background information and highlights the new aspects of the research and its impact on the design of new strategies or the identification of new targets for therapeutic intervention. There is a significant need for a book on this topic, as interest in the cytoskeleton continues to grow as causes and cures for cytoskeletal diseases are further explored in biomedical research. This book is essential reading for scientists, students, and teachers interested in expanding their knowledge related to the cytoskeleton. New researchers entering the field will find classic and well as contemporary information not easily found in the current literature or internet resources.
Book Synopsis Cell Mechanics and Tumor Development by : Ronald L. Huston
Download or read book Cell Mechanics and Tumor Development written by Ronald L. Huston and published by . This book was released on 2020 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cytoskeletal Mechanisms During Animal Development by :
Download or read book Cytoskeletal Mechanisms During Animal Development written by and published by Academic Press. This book was released on 1996-02-09 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cytoskeleton is central to cell biology and is instrumental in developmental events. Volume 31 is divided into two major sections: nonchordate development and chordate development. Summaries of each section compare evolutionary conservation among organisms.
Book Synopsis The Cytoskeleton in Cell Differentiation and Development by : Ricardo B. Maccioni
Download or read book The Cytoskeleton in Cell Differentiation and Development written by Ricardo B. Maccioni and published by Oxford University Press, USA. This book was released on 1987 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Regulation of Cell Proliferation and Differentiation by : Warren Nichols
Download or read book Regulation of Cell Proliferation and Differentiation written by Warren Nichols and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1974 The National Institute on Aging established a somatic cell genetic resource for aging research at the Institute for Medical Research in Camden, New Jersey. Within this program there is a yearly workshop to promote theory and concept develop ment in aging research with the specific purpose of addressing the use of genetically marked cells for aging research and to stimulate interest in aging research by workers in a variety of disciplines. This monograph, The Regulation of Cell Proliferation and Differentiation, is the result of the first workshop held May 15-17, 1975. The concept of the workshop was to consider two main areas: First, a discussion of clinical syndromes expressing as a major manifestation excessive growth, deficient growth or failure to thrive; and second, to present work in cellular and molecular biology on a model system suitable for in vitro study of regulation of cell proliferation and diff2rentiation. The model selected for this was skeletal muscle. It has been widely accepted that normal somatic cells from individual human donors display limited replicative lifespans when cultivated in vitro (1,2). That such "clonal senescence" may be related to in vivo aging is suggested by observations relating the replicative lifespans of cultures to donor age (3-5,13) donor genotype (4-7) and donor's tissue of origin (5,8). A variety of theories have been developed to explain in vitro clonal senescence (9).
Book Synopsis Membrane and Cytoskeleton Mechanics by : Yuan Lin
Download or read book Membrane and Cytoskeleton Mechanics written by Yuan Lin and published by Frontiers Media SA. This book was released on 2022-02-11 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cellular Mechanics in Differentiation and Growth by : Dorothea Rudnick
Download or read book Cellular Mechanics in Differentiation and Growth written by Dorothea Rudnick and published by . This book was released on 2016-04-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here are the recent investigations of several distinguished biologists originally presented at the Fourteenth Symposium of the Society for the Study of Development and Growth. New tools and methods are used as they examine a wide range of cellular activities at various levels of plant and animal life. Originally published in 1956. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Book Synopsis Cell Growth, Differentiation and Senescence by : George P. Studzinski
Download or read book Cell Growth, Differentiation and Senescence written by George P. Studzinski and published by Oxford University Press. This book was released on 1999 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are three main themes running through this volume. First, basic methods for measurement of cell proliferation are introduced and explained with reference to various systems, primarily in vitro, but in vivo procedures are also illustrated. The second theme is growth signalling, and isexemplified by methods for the analysis of transduction pathways for growth, beginning at the cell membrane and leading to the cell nucleus. The last theme presented here is growth cessation, illustrated by several systems for induction of cell differentiation, and of cell senescence. The emphasisthroughout the book is on human cell systems, making it particularly relevant to scientists interested in human disease, especially cancer. Importantly, well proved methods for studying cell growth are supplemented by some novel approaches, e.g., studies of cell cycle checkpoints, cell spheroids,and nuclear architecture. Only two chapters have been retained, in an updated form from Cell Growth and Apoptosis, the predecessor volume. The book is written by a team of scientists highly experienced in procedures they describe, and offer details and hints found valuable in their ownlaboratories; thus, variants of the same general methods can be found in different chapters. These should be helpful to beginning as well as experienced investigators, and are designed to stimulate new approaches to old and new questions.
Book Synopsis Cell Cycle and Cell Differentiation by : J. Reinert
Download or read book Cell Cycle and Cell Differentiation written by J. Reinert and published by Springer. This book was released on 1975 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myogenesis: a cell lineage interpretation; The organization of red cell differentiation; The cell cycle, cell lineage, and neuronal specificity; Neurogenesis and the cell cycle; The cell cycle and cell differentiation in the Drosophila ovary; The cell cycle and cellular differentiation in insects; Nuclear transplantation and the cyclic reprogramming of gene expression; Morphogenesis during the cell cycle of the prokayote, caulobacter crescentus; Cell division and the determination phase of cytodifferentiation in plants; The cell cycle and tumorigenesis in plants; Cell cycle and liver function; Histones, differentiation, and the cell cycle; Cell changes in neurospora.
Book Synopsis Cell Cycle and Cell Differentiation by : J. Reinert
Download or read book Cell Cycle and Cell Differentiation written by J. Reinert and published by Springer. This book was released on 2014-04-18 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is instructive to compare the response of biologists to the two themes that comprise the title of this volume. The concept of the cell cycle-in contra distinction to cell division-is a relatively recent one. Nevertheless biologists of all persuasions appreciate and readily agree on the central problems in this area. Issues ranging from mechanisms that initiate and integrate the synthesis of chro mosomal proteins and DNA during S-phase of mitosis to the manner in which assembly of microtubules and their interactions lead to the segregation of metaphase chromosomes are readily followed by botanists and zoologists, as well as by cell and molecular biologists. These problems are crisp and well-defined. The current state of "cell differentiation" stands in sharp contrast. This, one of the oldest problems in experimental biology, almost defies definition today. The difficulties arise not only from a lack of pertinent information on the regulatory mechanisms, but also from conflicting basic concepts in this field. One of the ways in which this situation might be improved would be to find a broader experimental basis, including a better understanding of the relationship between the cell cycle and cell differentiation.
Book Synopsis Cytoskeleton - Structure, Dynamics, Function and Disease by :
Download or read book Cytoskeleton - Structure, Dynamics, Function and Disease written by and published by . This book was released on 19?? with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Study of Cell Growth, Division and Programmed Differentiation by Simulation and Experiments by : Satyaprakash Nayak
Download or read book A Study of Cell Growth, Division and Programmed Differentiation by Simulation and Experiments written by Satyaprakash Nayak and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deregulation of cellular mechanisms responsible for cell growth, reproduction and differentiation is one of the hallmarks of all cancers. This study aims to elucidate the mechanisms underlying cell growth and differentiation using innovative computational and experimental tools. In the current study, we first review the basic cell cycle mechanisms in a typical eukaryotic cell (Chapter 1). In chapter 2, we analyze three published cell-cycle models and test our hypothesis that cell-cycle control architecture follow the "robust yet fragile" or the Highly Optimized Tolerance (HOT) paradigm. A very important fragile sub-system in the cell-cycle, revealed in our analysis of the cell-cycle models is protein translation. In chapter 3, we study the process of protein translation in detail, especially protein translation initiation. We formulate a detailed, mechanistic model of translation initiation from interactions validated in the literature. Novel systemsbiology tools such as coupling analysis are developed and employed to gain insight into critical components of translation initiation. This study reveals the importance of the Akt and mTOR proteins in the presence of growth factors and that of negative regulators such as PTEN and 4E-BP1 in their absence. Differentiation is the process by which a less specialized cell becomes more committed in its lineage, in response to the external environment. Chapter 4 presents an experimental study of Arsenic Trioxide on Human Leukemia (HL-60) myeloblastic cells. Our results show that Arsenic Trioxide enhances All Trans Retinoic Acid (ATRA) induced differentiation of HL-60 cells. This increase in differentiation is associated with an increase in the sustained Mitogen Activate Protein Kinase (MAPK) response. Chapter 5 presents an ensemble approach to model the response of HL-60 cells to ATRA and the role of sustained MAPK in differentiation. The model and its analysis present a systematic method to understand mechanisms involved in programmed cell differentiation in adult stem cells. In Chapter 6, we present a model combining hormone growth factor receptor signaling and prostate specific antigen (PSA) in LNCaP prostate adenocarcinoma cells. Finally, the concluding chapter discusses future directions of the current study.
Book Synopsis Functions of the Cytoskeleton in Cell Growth, Organization and Differentiation by :
Download or read book Functions of the Cytoskeleton in Cell Growth, Organization and Differentiation written by and published by . This book was released on 1995 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biomedical Index to PHS-supported Research by :
Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1990 with total page 1060 pages. Available in PDF, EPUB and Kindle. Book excerpt:
