Cytokines in Inflammatory Bowel Disease

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Publisher :
ISBN 13 : 9783540603269
Total Pages : 270 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Cytokines in Inflammatory Bowel Disease by : Claudio Fiocchi

Download or read book Cytokines in Inflammatory Bowel Disease written by Claudio Fiocchi and published by . This book was released on 1996 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pathogenesis of both forms of inflammatory bowel disease, Crohn's disease and ulcerative colitis, depends on complex immune abnormalities, and the investigation of cytokines has become critical to basic, clinical and therapeutic aspects of these enigmatic entities. This book offers clear, concise, state-of-the-art information on the role of various immunoregulatory and pro-inflammatory mediators in Crohn's disease and ulcerative colitis. Each cytokine is analyzed in regard to pathogenic and clinical implications, taking advantage of information derived from patients, animal models, as well as immunological and molecular in vitro systems. This volume is of interest to gastroenterologists, clinical investigators, immunologists, cell biologists and any professional interested in mucosal immunity and inflammation.

Cytokines and Intestinal Mucosal Immunity

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Publisher : Frontiers Media SA
ISBN 13 : 2889711684
Total Pages : 142 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Cytokines and Intestinal Mucosal Immunity by : Fabio Cominelli

Download or read book Cytokines and Intestinal Mucosal Immunity written by Fabio Cominelli and published by Frontiers Media SA. This book was released on 2021-08-10 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Inflammatory Bowel Diseases

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792387503
Total Pages : 340 pages
Book Rating : 4.3/5 (875 download)

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Book Synopsis Advances in Inflammatory Bowel Diseases by : P. Rutgeerts

Download or read book Advances in Inflammatory Bowel Diseases written by P. Rutgeerts and published by Springer Science & Business Media. This book was released on 1998-12-31 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ulcerative colitis and Crohn's disease remain a great therapeutic challenge to the medical community. In recent years knowledge about the pathogenesis of these diseases has progressed rapidly but the cause of the diseases remains completely unknown. It has become clear that dysregulation of the mucosal immune system is the basis for the chronic evolution of the diseases in a genetically susceptible population. Exciting new therapeutic approaches have been attempted in the last couple of years and cytokine and anti-cytokine treatments in particular seem very promising, especially in intractable disease. The format of the Falk Symposium 106 on `Advances in Inflammatory Bowel Diseases', held in Brussels, Belgium, June 18-20, 1998, was somewhat innovative as each session attempted to link the new insights into pathogenetic mechanisms with new therapeutic approaches, resulting in optimal information transfer. The classic therapeutic schemes were updated with a special focus on step-wise build-up of therapy.

Inflammatory Bowel Disease

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Publisher : John Wiley & Sons
ISBN 13 : 1444359118
Total Pages : 1429 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Inflammatory Bowel Disease by : Stephan R. Targan

Download or read book Inflammatory Bowel Disease written by Stephan R. Targan and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 1429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the state-of–the-art book on inflammatory bowel disease you have been waiting for Written and edited by international experts in gastroenterology this up-to-date volume provides a complete review of the basic science behind inflammatory bowel disease (IBD), as well as evidence-based clinical guidance on diagnosis, treatment and long-term management of IBD. In 50 chapters the authors cover the latest and most promising treatment modalities and the science behind them. There are chapters which cover the advances in the medical and surgical treatment of conditions such as Crohn's disease and ulcerative colitis, as well as chapters focusing on nutrition, imaging and complementary medicine. This is an invaluable information resource for all those in the medical team treating patients with IBD. Whether you are a gastroenterologist, gastrointestinal surgeon or GI nurse specialist this book deserves a place in your library.

Cytokines in Inflammatory Bowel Disease

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (85 download)

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Book Synopsis Cytokines in Inflammatory Bowel Disease by : John Robert Lowes

Download or read book Cytokines in Inflammatory Bowel Disease written by John Robert Lowes and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Colitis-Associated Cancer

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Publisher : Springer
ISBN 13 : 4431555226
Total Pages : 151 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Colitis-Associated Cancer by : Masato Kusunoki

Download or read book Colitis-Associated Cancer written by Masato Kusunoki and published by Springer. This book was released on 2015-10-01 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the number of patients with colitis-associated cancer (CAC) is on the increase, the purpose of this book is to review the latest topics concerning management of the disease. In recent years, the diagnostic power of endoscopy and molecular pathology has also grown tremendously, as a result of which they now have a far greater influence on the treatment of CAC. At the moment, appropriate monitoring programs for ulcerative colitis and Crohn’s disease remain uncertain. At the same time, the latest findings on DNA methylation and microRNAs hold the promise of making revolutionary changes in these areas. Moreover, recent drug advances in the treatment of inflammatory bowel diseases have changed surgical indications. On the other hand, the indication of mucosectomy on colorectal cancer in ulcerative colitis and prophylactic abdominoperineal resection for Crohn’s disease remain controversial. This book provides the latest information on the remaining issues of CAC from the point of view of expert surgeons.

Enteric Glia

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Publisher : Biota Publishing
ISBN 13 : 1615046615
Total Pages : 72 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Enteric Glia by : Brian D. Gulbransen

Download or read book Enteric Glia written by Brian D. Gulbransen and published by Biota Publishing. This book was released on 2014-07-01 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often referred to as the “little brain” in the gut because the ENS is more similar in size, complexity and autonomy to the central nervous system (CNS) than other components of the autonomic nervous system. Like the brain, the ENS is composed of neurons that are surrounded by glial cells. Enteric glia are a unique type of peripheral glia that are similar to astrocytes of the CNS. Yet enteric glial cells also differ from astrocytes in many important ways. The roles of enteric glial cell populations in the gut are beginning to come to light and recent evidence implicates enteric glia in almost every aspect of gastrointestinal physiology and pathophysiology. However, elucidating the exact mechanisms by which enteric glia influence gastrointestinal physiology and identifying how those roles are altered during gastrointestinal pathophysiology remain areas of intense research. The purpose of this e-book is to provide an introduction to enteric glial cells and to act as a resource for ongoing studies on this fascinating population of glia. Table of Contents: Introduction / A Historical Perspective on Enteric Glia / Enteric Glia: The Astroglia of the Gut / Molecular Composition of Enteric Glia / Development of Enteric Glia / Functional Roles of Enteric Glia / Enteric Glia and Disease Processes in the Gut / Concluding Remarks / References / Author Biography

Induction and Modulation of Gastrointestinal Inflammation

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792387473
Total Pages : 350 pages
Book Rating : 4.3/5 (874 download)

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Book Synopsis Induction and Modulation of Gastrointestinal Inflammation by : A. Stallmach

Download or read book Induction and Modulation of Gastrointestinal Inflammation written by A. Stallmach and published by Springer Science & Business Media. This book was released on 1998-12-31 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, the proceedings of Falk Symposium No. 104, organized in collaboration with the Society of Mucosal Immunology, and held in Saarbrucken, Germany, March 5-7 1998, is centered around the immunological mechanisms of mucosal protection and their disturbances leading to intestinal inflammation and destruction. This is a rapidly expanding field involving recent knowledge of basic immunology and cell biology as well as clinical observations. The conference and this book summarize very recent data in this field and suggest strategies for future research and clinical applications, and will be of interest to both basic scientists and clinicians.

Inflammatory Bowel Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 9400903715
Total Pages : 436 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Inflammatory Bowel Disease by : L.R. Sutherland

Download or read book Inflammatory Bowel Disease written by L.R. Sutherland and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: The inflammatory bowel diseases, of unknown etiology and for which there are no cures, continue to attract the attention and interest of gastroenterologists, internists and surgeons. International symposia are common and it is safe to say that there is at least one major symposium held somewhere in the world each year. This book encompasses the proceedings of two recent symposia held in Victoria, British Columbia, Canada. The symposia were the fifth and sixth international meetings focused on inflammatory bowel disease in Canada in the last eight years. Once again they were sponsored by Axcan Pharma, Inc. (formerly Interfalk Canada, Inc.) and endorsed by the Canadian Association of Gastroenterology. As has become traditional at such meetings the faculty was drawn from an international roster ofleaders in the field of inflammatory bowel disease and gastroenterology. The chapters of the proceedings provide a timely, up-to-date review of the major issues, including those within the realm of basic science and others dealing with clinical problems. The first symposium, 'Basic Research and Clinical Implications', was co-ordinated by John Wallace in association with Stephen Collins and Stephan Targan. The themes of this section were organized under the general topics of predisposing factors (genetics, animal models, infection, permeability, and immune deficits) and the pathophysiology of intestinal inflammation. The second symposium, Trends in Therapy' was organized by Lloyd Sutherland along with Franc;:ois Martin, Robin McLeod and Noel Williams.

Inflammatory Bowel Disease

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Publisher : BoD – Books on Demand
ISBN 13 : 953307891X
Total Pages : 348 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Inflammatory Bowel Disease by : Sami Karoui

Download or read book Inflammatory Bowel Disease written by Sami Karoui and published by BoD – Books on Demand. This book was released on 2012-01-27 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is dedicated to inflammatory bowel disease, and the authors discuss the advances in the pathogenesis of inflammatory bowel disease, as well as several new parameters involved in the etiopathogeny of Crohn's disease and ulcerative colitis, such as intestinal barrier dysfunction and the roles of TH 17 cells and IL 17 in the immune response in inflammatory bowel disease. The book also focuses on several relevant clinical points, such as pregnancy during inflammatory bowel disease and the health-related quality of life as an end point of the different treatments of the diseases. Finally, advances in management of patients with inflammatory bowel disease are discussed, especially in a complete review of the recent literature.

New Cytokines as Potential Drugs

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Publisher : Springer
ISBN 13 : 3034884567
Total Pages : 166 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis New Cytokines as Potential Drugs by : Satwant K. Narula

Download or read book New Cytokines as Potential Drugs written by Satwant K. Narula and published by Springer. This book was released on 2012-11-19 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past ten years, a number of cytokines and growth factors have proven to be as effective therapeutics. While these products have certainly established recombinant biologics as a major pharmaceutical growth sector, the continued interest in this class of drugs arises from the fact that today we have a far better understanding of the human immune response, both at a cellular and molecular level. This has resulted in a more methodical characterisation of these factors which has given clinical researchers an opportunity to plan Phase 1 clinical trials that can provide substantial information on the activity of the cytokine in humans. Currently, a great deal of effort is also being channelled into identifying cytokines from the various DNA databases. Our major objective for this book is to profile cytokines that have been recently identified. The therapeutic potential of these cytokines based on their known properties will be discussed by the authors. The main aim of this book is to provide...

Inflammatory Bowel Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 0387258086
Total Pages : 891 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Inflammatory Bowel Disease by : Stephan R. Targan

Download or read book Inflammatory Bowel Disease written by Stephan R. Targan and published by Springer Science & Business Media. This book was released on 2007-05-16 with total page 891 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammatory Bowel Disease: From Bench to Bedside is a detailed and comprehensive story of the local and systemic pathophysiology of intestinal inflammation including management strategies. Research advances and current concepts of etiopathogenesis in the context of what is already known of the clinicopathologic features of these disorders is explored. This volume blends recent advances in the basic and clinical sciences as they relate to inflammatory bowel disease and emphasizes the effectiveness of a team approach of basic scientists and clinician investigators in this field.

Mechanisms of Intestinal Inflammation

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792387879
Total Pages : 246 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis Mechanisms of Intestinal Inflammation by : R. Duchmann

Download or read book Mechanisms of Intestinal Inflammation written by R. Duchmann and published by Springer Science & Business Media. This book was released on 2004-04-30 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years considerable progress has been achieved in regard to our understanding of the induction and modulation of the immune response in the intestinal mucosa. It is clear that this mucosal immune reaction is predominantly steered by certain T-cell populations, which are characterized by their cytokine secretion profile. Less well known are the conditions under which the uptake and processing of a specific antigen leads to a certain immune response, whether it be protective, tolerant or inflammatory. However, here again distinct progress has been made in our understanding. Equally significant for immune regulation in the gut appears to be so-called innate immunity. Every shift of equilibrium in the highly regulated mucosal immune reaction is accompanied by an inflammatory reaction and destruction of the mucosa. In nearly all cases, this inflammatory response is dependent on the presence of bacterial intestinal flora. This book, the proceedings of Falk Symposium 133 on Mechanisms of Intestinal Inflammation: Implications for Therapeutic Intervention in IBD', held in Berlin, Germany, on 10-11 June 2003, summarizes present knowledge in the area of unspecific and specific immune reactions in the gut, recording the gaps in our knowledge and, in particular, presenting the possibilities of targeted intervention. The link to inflammatory bowel diseases - Crohn's disease and ulcerative colitis - is always in focus. Chapters by an international panel of basic scientists, clinical researchers and clinicians also record the problems which can originate through today's possible modulation of the immune reaction, setting the basis for review of clinical problems. This book is valuable readings for all scientists and physicians, who, from different perspectives, have an interest in research on IBD and in the clinical management of these diseases.

Cytokines in Chronic Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis) in Children

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Publisher :
ISBN 13 :
Total Pages : 148 pages
Book Rating : 4.:/5 (843 download)

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Book Synopsis Cytokines in Chronic Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis) in Children by : Christian Brägger

Download or read book Cytokines in Chronic Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis) in Children written by Christian Brägger and published by . This book was released on 1995 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:

New Insights into Inflammatory Bowel Disease

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Publisher : BoD – Books on Demand
ISBN 13 : 9535127543
Total Pages : 266 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis New Insights into Inflammatory Bowel Disease by : Samuel Huber

Download or read book New Insights into Inflammatory Bowel Disease written by Samuel Huber and published by BoD – Books on Demand. This book was released on 2016-10-26 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The incidence of chronic inflammatory and autoimmune diseases is steadily increasing. Inflammatory bowel disease (IBD) is one example of a chronic inflammatory disease, which primarily affects the intestine but may also affect extraintestinal organs. The exact pathogenesis of IBD is currently unknown. However, it is clear that the pathogenesis is complex, involving barrier defects, changes in the intestinal microbiome, and chronic immune activation. This book aims to summarize basic aspects of these complex interactions between barrier function, microbiome, and the immune system. Of note, there is currently no cure for IBD. However, several therapies have evolved in the last years, which are overall able to-at least temporarily-suppress IBD. These therapies and the underlying mechanism are discussed.

Origins and Directions of Inflammatory Bowel Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 9401003262
Total Pages : 264 pages
Book Rating : 4.4/5 (1 download)

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Book Synopsis Origins and Directions of Inflammatory Bowel Disease by : Joseph B. Kirsner

Download or read book Origins and Directions of Inflammatory Bowel Disease written by Joseph B. Kirsner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few human illnesses today are so challenging, medically, scientifically, and socio-economically, as the "nonspecific" inflammatory bowel diseases (IBD): ulcerative colitis and Crohn's disease. Originating several centuries ago but essentially diseases of the 20th century, often attacking children and young adults, involving all bodily systems as well as the gastrointestinal tract, ulcerative colitis and Crohn's disease have emerged in recent decades as among the more "glamorous" unsolved diseases, presenting unusual opportunities for insightful clinical and investigative study. Many of the prevailing concepts originated during the early and mid 20th century. The purpose of Origins and Directions of Inflammatory Bowel Disease is to review these earlier studies and their evolution "from the mystical to the molecular," and guide investigators and physicians through the challenging clinical and scientific maze of IBD.

Immune Mechanisms in Inflammatory Bowel Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 0387337784
Total Pages : 262 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Immune Mechanisms in Inflammatory Bowel Disease by : Richard Blumberg

Download or read book Immune Mechanisms in Inflammatory Bowel Disease written by Richard Blumberg and published by Springer Science & Business Media. This book was released on 2007-02-26 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Mechanisms in Inflammatory Bowel Disease is a highly, concise update of the most recent advances in the immunobiology, genetics and microbiology related to Inflammatory Bowel Disease. This book broadly treats the topics that lead to understanding of the pathogenesis of this disease in an organized, systematic approach.