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Cytokine Interactions
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Book Synopsis Cytokine Interactions and Their Control by : A. Baxter
Download or read book Cytokine Interactions and Their Control written by A. Baxter and published by . This book was released on 1991-12-20 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a group of international experts with the intention of furthering the understanding of cytokines' progress in recent years. Coverage includes new cytokines continually being cloned plus recent studies of their interaction and control.
Book Synopsis Military Strategies for Sustainment of Nutrition and Immune Function in the Field by : Institute of Medicine
Download or read book Military Strategies for Sustainment of Nutrition and Immune Function in the Field written by Institute of Medicine and published by National Academies Press. This book was released on 1999-05-13 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.
Book Synopsis An Introduction to Neuroendocrinology by : Richard E. Brown
Download or read book An Introduction to Neuroendocrinology written by Richard E. Brown and published by Cambridge University Press. This book was released on 1994-01-27 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.
Book Synopsis Cytokine-Ion Channel Interactions in Pulmonary Inflammation by : István Vadász
Download or read book Cytokine-Ion Channel Interactions in Pulmonary Inflammation written by István Vadász and published by Frontiers Media SA. This book was released on 2019-01-24 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic assembles original contributions and reviews from an international consortium of PIs related to interactions between pro-inflammatory cytokines and ion channels during acute lung injury and chronic heart failure.
Book Synopsis Cytokine Interactions by : Donald Metcalf
Download or read book Cytokine Interactions written by Donald Metcalf and published by . This book was released on 1991-01-01 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Stem Cells Origins of Cytokine Interactions by : Prasad S. Koka
Download or read book Stem Cells Origins of Cytokine Interactions written by Prasad S. Koka and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: CD34+ pluripotent hematopoietic stem cells (HSCs) are generally involved in all aspects of the human system as well as in the stem cell therapeutic strategies, as in bone marrow transplantation (BMT). This book deals with several original research articles on HSC proliferation and containment. Lineage directed differentiation of HSCs and use of easily available herbal extracts for greatly increased proliferation into erythrocytes to treat thrombocytopenia are herein reported. HSCs respond to the growth factors and the herbal medicine is a welcome substitute with lack of known side effects for treatment purposes. However molecular mechanisms as in signal transduction are more easily deciphered than those derived from the herbs which may well be taken up for future studies. Mutations in the signal transduction genes such as JAK-2 have been shown to cause dysregulation of the CD34+ cell differentiation causing erythrocytosis, which is the reverse of thrombocytopenia, both of which are undesirable clinical consequences. Erythrocytes have been shown to date back to ancient tissues from the fossils.
Book Synopsis Bacteria-cytokine Interactions in Health and Disease by : Brian Henderson
Download or read book Bacteria-cytokine Interactions in Health and Disease written by Brian Henderson and published by Ashgate Publishing. This book was released on 1998 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together the current literature on bacterial virulence and on cytokines to produce a synthesis that attempts to explain how infectious and commensal bacteria interact with man. An explanation is provided for this failure to respond to normal microflora.
Book Synopsis Cytokines and the CNS by : Richard M. Ransohoff
Download or read book Cytokines and the CNS written by Richard M. Ransohoff and published by CRC Press. This book was released on 2005-10-31 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides Insight into How Cytokine Action Impacts the Physiology and Pathology of the CNS. As with the first edition of Cytokines and the CNS, this completely updated and revised edition introduces neurobiologists to cytokine biology and immunologists to the unique functions of cytokines in CNS physiology. The dramatically accelerating interest in cytokines and cytokine/chemokine signaling over the past several years has encouraged an explosion of literature on cytokines. The similarity between factors involved in inflammation or immunity, and those implicated in neural development, physiology, and repair has become so apparent that familiarity with cytokines must now be considered an essential element in the neurobiologist’s cognitive tool-kit. Conversely, for immunobiologists, the concepts elaborated by neurobiologists to understand developmental patterning and networked organ function continue to evolve in such a way that comprehension of cytokine action in the CNS can only enhance a further understanding of immune system function. Cytokines and the CNS, Second Edition is patterned after the first edition; however, the wealth of knowledge now available adds a tremendous amount of insight and new implications. To guarantee a fresh perspective, the editors made a conscious choice to utilize an entirely new set of contributors, all experts in various aspects of cytokine research. Cytokines and the CNS, Second Edition starts with a chapter on the CNS, focusing on pathological reactions to insult. Next, come three chapters on cytokine biology, followed by four chapters that integrate cytokine biology into basic CNS processes (development; inflammation; immunity; degeneration/repair), after which five chapters apply this body of knowledge to disease or pathology. The book closes with a look at the application of cytokine biology to the treatment of disease, a brand new area of research.
Book Synopsis Cytokines and Pain by : L.R. Watkins
Download or read book Cytokines and Pain written by L.R. Watkins and published by Springer. This book was released on 2013-03-08 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the past few years, it has become recognized that the immune system communicates to the brain. Substances released from activated immune cells (cytokines) stimulate peripheral nerves, thereby signaling the brain and spinal cord that infection/inflammation has occurred. Additionally, peripheral infection/inflammation leads to de novo synthesis and release of cytokines within the brain and spinal cord. Thus, cytokines effect neural activation both peripherally and centrally. Through this communication pathway, cytokines such as interleukin-1, interleukin-6 and tumor necrosis factor markedly alter brain function, physiology and behavior. One important but underrecognized aspect of this communication is the dramatic impact that immune activation has on pain modulation. The purpose of this book is to examine, for the first time, immune-to-brain communication from the viewpoint of its effect on pain processing. It is aimed both at the basic scientist and health care providers, in order to clarify the major role that substances released by immune cells play in pain modulation. This book contains chapters contributed by all of the major laboratories focused on understanding how cytokines modulate pain. These chapters provide a unique vantage point from which to examine this question, as the summarized work ranges from evolutionary approaches across diverse species, to the basics of the immune response, to the effect of cytokines on peripheral and central nervous system sites, to therapeutic potential in humans.
Book Synopsis Cell-Cell Interactions in the Release of Inflammatory Mediators by : Patrick Y-K Wong
Download or read book Cell-Cell Interactions in the Release of Inflammatory Mediators written by Patrick Y-K Wong and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume constitutes. in part. the proceedings of the symposium on "Cell-Cell Interaction and Release of Inflammatory Mediators" organized by Drs. Patrick Y-K Wong and Charles N. Serhan and presented at the FASEB meeting in Washington. D.C. in April. 1990. It contains chapters by the symposium speakers as well as contributions from investigators in this field. Readers will find exciting advances in this volume. which contains chapters dedicated to state-of-the-art knowledge in the field of Cell-Cell Interaction and the functions of released mediators in inflammatory diseases. This book includes "cutting edge" investigations on transcellular eicosanoid biosynthesis. cytokines. PAF, and adhesion as well as interactions of inflammatory cells with endothe 1 i um. 1 ung • and kidney. A 1 so. the contro 1 and regu 1 at ion of renal function by lipid mediators generated during cell-cell i nteracti ons between rena 1 mesangi a 1 cells and 1 eukocytes has generated insight into the cell biology and regulatory role of these mediators in the kidney. Moreover. the relationship between these areas is discussed in sequelae of both asthmatic and renal diseases. We hope that some of the enthusiasm and excitement present in this research are also evident here and that this volume will serve as a reference for researchers. teachers. and students to survey thi s rapidly growing field.
Book Synopsis Stem Cells Origins of Cytokine Interactions by : Prasad S. Koka
Download or read book Stem Cells Origins of Cytokine Interactions written by Prasad S. Koka and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: CD34+ pluripotent hematopoietic stem cells (HSCs) are generally involved in all aspects of the human system as well as in the stem cell therapeutic strategies, as in bone marrow transplantation (BMT). This book deals with several original research articles on HSC proliferation and containment. Lineage directed differentiation of HSCs and use of easily available herbal extracts for greatly increased proliferation into erythrocytes to treat thrombocytopenia are herein reported.HSCs respond to the growth factors and the herbal medicine is a welcome substitute with lack of known side effects for treatment purposes. However molecular mechanisms as in signal transduction are more easily deciphered than those derived from the herbs which may well be taken up for future studies. Mutations in the signal transduction genes such as JAK-2 have been shown to cause dysregulation of the CD34+ cell differentiation causing erythrocytosis, which is the reverse of thrombocytopenia, both of which are undesirable clinical consequences! Erythrocytes have been shown to date back to ancient tissues from the fossils.
Book Synopsis Cytokine Inhibitors by : Gennaro Ciliberto
Download or read book Cytokine Inhibitors written by Gennaro Ciliberto and published by CRC Press. This book was released on 2000-11-14 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compiling an up-to-date and detailed survey of the role cytokines play in cell-to-cell communication, development, and differentiation, this comprehensive reference highlights the medical advantages of cytokine inhibition and pursues novel methods of discovery for more potent and specific blocking agents. Investigates the pathogenic role of cytokines and the potential of cytokine inhibitors as anti-inflammatory, anticancer, antiviral agents! Written by 25 recognized experts revealing recent breakthroughs in research, Cytokine Inhibitors illustrates cases of naturally produced or in vitro engineered polypeptide cytokine blocking agents describes all possible approaches to cytokine inhibitors, including monoclonal antibodies, soluble receptors, engineered mutant cytokines, and small-molecular-weight receptor antagonists and signaling inhibitors clearly explains the homeostatic function of cytokine inhibition and verifies therapeutic approaches effecting natural responses in organisms discusses the results of clinical trials and therapeutic applications of first-generation recombinant receptor antagonists, such as the potential of tumor necrosis factor antagonists as prominent tools in the therapy of chronic inflammatory conditions concentrates on the clinical development of second-generation small-molecular-weight, orally bioavailable cytokine inhibitors reviews the improved understanding of intracellular signaling pathways, the structural determinants responsible for cytokine-receptor interaction lists the three-dimensional structure, relevant receptors, and intracellular tyrosine kinases of cytokines and much more! Containing over 1400 references as well as tables and drawings, Cytokine Inhibitors serves as an exemplary reference for basic and clinical immunologists; allergists; biochemists; pathologists, hematologists; experimental, cell, and molecular biologists; rheumatologists; infectious disease specialists; medicinal chemists; and medical school and upper-level undergraduate and graduate students in these disciplines.
Book Synopsis Cytokines and Cytokine Receptors by : Constantin A. Bona
Download or read book Cytokines and Cytokine Receptors written by Constantin A. Bona and published by CRC Press. This book was released on 2001-03-07 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of cytokine research is expanding at a rapid pace Contributions from the major leading groups in the world on the structure and biological properties of cytokine and cytokine receptors, as well as integrated reviews on cytokines in various physiological and pathological conditions were presented in three issues of International Reviews of Immunology This collection of articles provided a unique source of information However, important discoveries are emerging very rapidly and some of the reviews written in 1997 are already outdated In this book, the editors assemble reviews that have been updated by their authors to include all the recent publications and unpublished data from the authors' laboratories This volume should serve as an excellent reference source for all those concerned by the multiple faces of cytokines in basic research and in the clinic
Book Synopsis Cytokines and Chemokines in Infectious Diseases Handbook by : Malak Kotb
Download or read book Cytokines and Chemokines in Infectious Diseases Handbook written by Malak Kotb and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of what is known about the role of cytokines and chemokines in a variety of human infectious diseases, including gram-negative and -positive infections, listeriosis, mycobacterial infections, lyme arthritis, pneumonia, fungal infections, HIV, leishmaniasis, and sepsis. The authors demonstrate the different cytokine and chemokine production profiles in response to a wide variety of pathogens and the importance of host genetic factors in determining the type and magnitude of responses to a given microorganism. They also critically evaluate the use of cytokines and anticytokines in the treatment of infectious diseases and show how knowledge of cytokine pleiotropic effects, redundancy, and the complexity of the cytokine network has led to better design and better outcomes in cytokine-based therapies for specific infections.
Book Synopsis Cytokines: Interleukins and Their Receptors by : Razelle Kurzrock
Download or read book Cytokines: Interleukins and Their Receptors written by Razelle Kurzrock and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, cytokine research has emerged as one of the most exciting and critical fields for providing fundamental knowledge of normal and abnormal human development. Today, it is apparent that cytokines orchestrate growth from the early embryonic stage to maturity and are responsible for the normal function of virtually every organ system. Furthermore, virtually all disease states have been associated, at least in part, with cytokine aberrations. In this volume, the editors have brought together internationally known experts in the field of interleukin research to provide a comprehensive review of the biology of the interleukins and their role in both health and illness, while maintaining a balance between the basic science and clinical aspects. Cytokines: Interleukins and their Receptors should be of interest to a wide variety of researchers including clinical hematologists, oncologists, immunologists, in addition to medical and PhD students and researchers with an interest in cytokines.
Book Synopsis Cytokines of the Lung by : J. Kelley
Download or read book Cytokines of the Lung written by J. Kelley and published by CRC Press. This book was released on 2022-04-19 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on all the major cytokine families, this reference book provides coverage of cytokine regulatory processes in the lung and other tissues and comprehensive descriptions of cytokine functions specific to the lung.;Discussing the diverse cytokine-binding proteins and the role of cytokines in tissue injury and repair processes and extracellular matrix regulations, the book supplies information on amino acid structure and gene regulatory sequences, examines the receptor biology of individual cytokines, illustrates cytokine interactions with their cognate receptors and surveys the phenotypic effects of individual cytokines on target cells. With over 2700 literature citations and figures, this book is a resource for pulmonologists, physiologists, immunologists, cell and molecular biologists, environmental toxicologists, oncologists, and graduate-level and medical school students in these disciplines.
Book Synopsis The Cytokine Network by : Frances R. Balkwill
Download or read book The Cytokine Network written by Frances R. Balkwill and published by Frontiers in Molecular Biology. This book was released on 2000 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytokines are soluble mediators of intercellular communication. They contribute to a chemical signalling language that regulates development, tissue repair, haemopoiesis, inflammation and the immune response. Potent cytokine polypepides have pleiotropic activities and functional redundancy.They act in a complex network where one cytokine can influence the production of, and response to, many other cytokines. In the past five years, this bewildering array of more than 100 effector molecules and associated cell surface receptors has been simplified by study of cytokine and cytokinereceptor structure; elucidation of convergent intracellular signalling pathways; and molecular genetics, and targeted gene disruption to 'knock-out' production of individual cytokines in mice. It is also now clear that the pathophysiology of infectious, autoimmune and malignant disease can bepartially explained by the induction of cytokines and the subsequent cellular response. Viral homologues exist for many cytokines and receptors and genetic variations in cytokine production may influence response to pathogenic stimuli. Cytokine and cytokine antagonists have shown therapeuticpotential in a number of chronic and acute diseases. The Cytokine Network: Frontiers in Molecular Biology is not a survey of individual cytokines, but guides the reader through the latest research on the cytokine network as a whole covering genomics, signalling pathways, control of the immuneresponse, and therapeutics.
