Current Topics in Microbiology and Immunology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642461182
Total Pages : 237 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Current Topics in Microbiology and Immunology by : W. Arber

Download or read book Current Topics in Microbiology and Immunology written by W. Arber and published by Springer Science & Business Media. This book was released on 2013-04-09 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ever since arbovirus infections became known and their relative importance assessed, experiments were designed to elucidate the mode of transmission and the most important natural hosts responsible for perpetuating the infection in nature. Human infections and the disease in wild rodents, birds, and domestic animals were studied in relation to viremia and distribution of the infectious agent in the organism. With increasing epidemiological studies it became apparent that the neural manifestations of the disease are very uncommon, confined only to a small percentage of individuals of the most susceptible species. Various factors have been proposed to explain why in certain instances the virus becomes establish ed in the central nervous system and causes a serious or lethal disease. For example, differences in the virulence of the virus strains, varying susceptibility of individuals of one species, or intercurrent circumstances facilitating access of the virus to the central nervous system were alleged. Also, various possible routes of entry of the virus into the brain and spinal cord have been considered.

Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitätsforschung

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Publisher : Springer Science & Business Media
ISBN 13 : 364265875X
Total Pages : 163 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitätsforschung by : W. Arber

Download or read book Current Topics in Microbiology and Immunology / Ergebnisse der Mikrobiologie und Immunitätsforschung written by W. Arber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Current Topics in Microbiology and Immunology / Ergebnisse der Microbiologie und Immunitätsforschung

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Publisher : Springer Science & Business Media
ISBN 13 : 3642659128
Total Pages : 165 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Current Topics in Microbiology and Immunology / Ergebnisse der Microbiologie und Immunitätsforschung by : W. Arber

Download or read book Current Topics in Microbiology and Immunology / Ergebnisse der Microbiologie und Immunitätsforschung written by W. Arber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prominent progress in molecular biology was only made when it became possible to separate functionally distinct molecules by taking advantage of their biophysical properties. Likewise, the analysis of the functions of hetero geneous populations of immunocompetent cells, as to the functional properties of their various subpopulations, can not be done until these can be isolated in reasonably pure form by selective fractionation. During the last few years significant advances have been made in this field, and cells have been separated according to size, density or charge (MILLER et aI. , 1969; SHORTMAN, 1968; ANDERSSON, 1973 c), or by taking advantage of more specific surface markers to allow selective depletion or enrichment of a given subpopulation of cells (WIGZELL and ANDERSSON, 1971). Although separation techniques have been used in a variety of cellular systems, they have been particularly useful in the study of reticuloendothelial cells and primarily in the study of cells partici pating in the immune responses. Quite extensive reviews have been written which well cover the methods used for separation of cells and the results obtained with the various approaches (WIGZELL and ANDERSSON, 1971; SHORTMAN, 1972). To review this work is becoming a more and more voluminous task. As data rapidly accumulate, we will not try to make such a complete review.

Current Topics in Microbiology and Immunology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 364265357X
Total Pages : 224 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Current Topics in Microbiology and Immunology by : H. G. Schweiger

Download or read book Current Topics in Microbiology and Immunology written by H. G. Schweiger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phenomena as diverse as tuberculin sensitivity, delayed sensitivity to soluble proteins other than tuberculin, contact allergy, homograft rejection, experimental autoallergies, and the response to many microorganisms, have been classified as members of the class of immune reactions known as delayed or cellular hypersensitivity. Similarities in time course, histology, and absence of detectable circulating immunoglobulins characterize these cell-mediated immune reactions in vivo. The state of delayed or cellular hypersensitivity can be transferred from one animal to another by means of sensitized living lymphoid cells (CHASE, 1945; LANDSTEINER and CHASE, 1942; MITCHISON, 1954). The responsible cell has been described by GOWANS (1965) as a small lymphocyte. Passive transfer has also been achieved in the human with extracts of sensitized cells (LAWRENCE, 1959). The in vivo characteristic of delayed hypersensitivity from which the class derives its name is the delayed skin reaction. When an antigen is injected intradermally into a previously immunized animal, the typical delayed reaction begins to appear after 4 hours, reaches a peak at 24 hours, and fades after 48 hours. It is grossly characterized by induration, erythyma, and occasionally necrosis. The histology of the delayed reaction has been studied by numerous investigators (COHEN et al., 1967; GELL and HINDE, 1951; KOSUNEN, 1966; KOSUNEN et al., 1963; MCCLUSKEY et al., 1963; WAKSMAN, 1960; WAKSMAN, 1962). Initially dilatation of the capillaries with exudation of fluid and cells occurs.

Current Topics in Microbiology and Immunology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642681204
Total Pages : 312 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Current Topics in Microbiology and Immunology by : W. Henle

Download or read book Current Topics in Microbiology and Immunology written by W. Henle and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several discoveries are noteworthy for allowing us to probe the recesses of the virus℗Ư infected cell and to search for cryptic viral genomes which might provide clues in our studies of cancer etiology or developmental biology. One of the most notable was the dis℗Ư covery of reverse transcriptase. This marked a momentous occasion in the history of molecular biology. Not only did it provide insight into the mechanism of persistence of retroviruses but it also provided us with an enzyme that could synthesize a DNA copy of any RNA. This DNA copy could then be used as a hybridization reagent to search for both complementary DNA and viral-specific RNA. Thus one could follow the course of any viral infection or probe in tumor cells for hidden viral genomes. Second, a great deal of credit must be given to the geneticists who isolated the various deletion mutants in the 'avian retrovirus system and thus provided us with the frrst means of isolating gene-spe℗Ư cific probes. Finally, the laboratories which have mapped the genome have provided us with the framework in which to ask very specific questions with our gene-specific probes. Recently, numerous excellent reviews concerning various aspects of the retroviruses have appeared. In this review I shall not even attempt to present a comprehensive review of retroviruses.

Desk Encyclopedia of General Virology

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Publisher : Academic Press
ISBN 13 : 0123751624
Total Pages : 663 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Desk Encyclopedia of General Virology by : Marc H.V. van Regenmortel

Download or read book Desk Encyclopedia of General Virology written by Marc H.V. van Regenmortel and published by Academic Press. This book was released on 2010-05-21 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, derived from Encyclopedia of Virology, provides an overview of the development of virology during the last ten years. Entries detail the nature, origin, phylogeny and evolution of viruses. It then moves into a summary of our understanding of the structure and assembly of virus particles and describes how this knowledge was obtained. Genetic material of viruses and the different mechanisms used by viruses to infect and replicate in their host cells are highlighted. The volume is rounded out with an overview of some major groups of viruses with particular attention being given to our current knowledge of their molecular biology. The most comprehensive single-volume source providing an overview of virology to non-specialists Bridges the gap between basic undergraduate texts and specialized reviews Concise and general overviews of important topics within the field will help when preparing for lectures, writing reports, or drafting grant applications

Advances in Virus Research

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Publisher : Academic Press
ISBN 13 : 0128024240
Total Pages : 337 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Advances in Virus Research by :

Download or read book Advances in Virus Research written by and published by Academic Press. This book was released on 2015-06-23 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology. - Contributions from leading authorities - Informs and updates on all the latest developments in the field

Animal Influenza

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Publisher : John Wiley & Sons
ISBN 13 : 1118924320
Total Pages : 678 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Animal Influenza by : David E. Swayne

Download or read book Animal Influenza written by David E. Swayne and published by John Wiley & Sons. This book was released on 2016-10-14 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Influenza, Second Edition is a comprehensive text on animal influenza. Organized by species, coverage includes avian, swine, equine and mammals, with each section including data on influenza viruses, the infection and disease they cause, and strategies used in control. Covers the full range of topics within avian, swine, equine and mammalian influenzas in one comprehensive and authoritative text Provides a summarization of peer-reviewed and empirical data on influenza viruses, the infection, and diseases they cause Discusses strategies used in control of the disease Leading experts are drawn together to provide an international and multi-disciplinary perspective Fuses latest developments in basic scientific research with practical guidance on management of the disease

Bacterial Adhesion to Host Tissues

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Publisher : Cambridge University Press
ISBN 13 : 1139437631
Total Pages : 358 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Bacterial Adhesion to Host Tissues by : Michael Wilson

Download or read book Bacterial Adhesion to Host Tissues written by Michael Wilson and published by Cambridge University Press. This book was released on 2010-01-28 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the adhesion of bacteria to their human hosts. Although adhesion is essential for maintaining members of the normal microflora in/on their host, it is also the crucial first stage in any infectious disease. It is important, therefore, to fully understand the mechanisms underlying bacterial adhesion so that we may be able to develop methods of maintaining our normal (protective) microflora, and of preventing pathogenic bacteria from initiating an infectious process. These topics are increasingly important because of the growing prevalence of antibiotic-resistant bacteria and, consequently, the need to develop alternative approaches for the prevention and treatment of infectious diseases. This book describes the bacterial structures responsible for adhesion and the molecular mechanisms underlying the adhesion process. It also deals with the consequences of adhesion for both the adherent bacterium and the host cell/tissue to which it has adhered.

Global Catastrophic Biological Risks

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Publisher : Springer Nature
ISBN 13 : 3030363112
Total Pages : 131 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Global Catastrophic Biological Risks by : Thomas V. Inglesby

Download or read book Global Catastrophic Biological Risks written by Thomas V. Inglesby and published by Springer Nature. This book was released on 2019-11-28 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on Global Catastrophic Biological Risks (GCBRs), a special class of infectious disease outbreaks or pandemics in which the combined capacity of the world’s private and government resources becomes severely strained. These events, of which the 1918 influenza pandemic is emblematic, cause severe disruptions in the normal functioning of the world, exact heavy tolls in terms of morbidity and mortality, and lead to major economic losses. GCBRs can be caused by any type of microorganism, and myriad contextual factors can influence their impact. Additionally, there are cascading questions that arise in connection with GCBR prediction, preparation, and response. This book gathers contributions from thought leaders who discuss the multi-faceted approaches needed in order to address this problem. From understanding the special characteristics of various microbes to financing challenges, the volume provides an essential primer on a neglected but highly relevant topic. Physicians, scientists, policymakers, public health practitioners and anyone with an interest in the field of pandemics, emerging infectious disease, biosecurity, and global health security will find it a valuable and insightful resource.

Immunobiology of the Shark

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Publisher : CRC Press
ISBN 13 : 1466595752
Total Pages : 322 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Immunobiology of the Shark by : Sylvia L. Smith

Download or read book Immunobiology of the Shark written by Sylvia L. Smith and published by CRC Press. This book was released on 2014-12-04 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunity studies in sharks over the past three decades have produced some remarkable discoveries. If one message rings true, it is that alternative animal model systems, such as sharks and their relatives, have contributed very substantially to a better understanding of the development evolution of our own immune system. Immunobiology of the Shark describes the cellular, genetic, and molecular specifics of immune systems in sharks. Diverse approaches were employed to study the immunobiology of the shark from basic microscopic observations to detailed genome annotation. The book also raises a series of fascinating questions, which can be addressed experimentally using today’s technology. This book will be a valuable resource for mainstream immunologists, comparative immunologists, geneticists, ecologists, evolutionary biologists, and investigators engaged in shark research. The book also aims to illustrate the magnificence of these animals as model systems and underscores the importance of their study to further understand their complex, and often enigmatic, biology.

RNA Interference

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Publisher : Springer Science & Business Media
ISBN 13 : 3540751572
Total Pages : 277 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis RNA Interference by : Patrick J. Paddison

Download or read book RNA Interference written by Patrick J. Paddison and published by Springer Science & Business Media. This book was released on 2008-01-01 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last few years the major effect that RNAi has had in invertebrate systems is beginning to take hold in mammalian systems through both single gene knockdown experiments and genome-scale screens. In the next decade, there will no doubt be both notable successes and failures as we attempt to apply this genetic tool to various biological problems. Through the introduction of RNAi, mammalian systems have finally gained admittance to the pantheon of model genetic systems.

Bunyaviridae

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Publisher : Springer Science & Business Media
ISBN 13 : 364276018X
Total Pages : 260 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Bunyaviridae by : Daniel Kolakofsky

Download or read book Bunyaviridae written by Daniel Kolakofsky and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been no literature up to now treating the Bunyaviridae in general as a family. The book demonstrates how they are maintained in nature and how they replicate and sometimes cause disease.

Attempts to Understand Metastasis Formation II

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Publisher : Springer Science & Business Media
ISBN 13 : 3642611095
Total Pages : 297 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Attempts to Understand Metastasis Formation II by : Ursula Günthert

Download or read book Attempts to Understand Metastasis Formation II written by Ursula Günthert and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the last decade the molecular biology of tumor models has revealed the identification of several metastasis- related molecules. These volumes attempt to review the most recent approaches of their mechanisms, regulation and way to treat their malignant alterations. The first volume covers the presentation of proteases and inhibitors and their role in invasion of tumor cells, also cell adhesion molecules and their interaction with the extracellular matrix. In the second volume the regulation of tumor progression and angiogenesis by cytokines, growth factors and motility factors is outlined. The third volume deals with detection of micrometastases and therapeutic approaches, such as immunotherapy, gene therapy, chemotherapy and surgical strategies to combat metastatic spread.

Adhesion Molecules and Chemokines in Lymphocyte Trafficking

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Publisher : CRC Press
ISBN 13 : 9789057022289
Total Pages : 268 pages
Book Rating : 4.0/5 (222 download)

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Book Synopsis Adhesion Molecules and Chemokines in Lymphocyte Trafficking by : Alf Hamann

Download or read book Adhesion Molecules and Chemokines in Lymphocyte Trafficking written by Alf Hamann and published by CRC Press. This book was released on 1998-01-26 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summarizes the latest research in the field, with particular emphasis on molecular mechanisms involved in lymphocyte traffic, for scientists, clinicians, and students. Subjects include the role of homing to mucosal tissue, adhesion molecules, and chemokines in regulation of lymphocyte and leukocyte migration, roles of integrins in the interactions of lymphocytes with intestinal mucosa, lymphocyte trafficking through the central nervous system, and implications for tumor immunotherapy. Includes bandw drawings. Annotation copyrighted by Book News, Inc., Portland, OR

Current Topics in Microbiology and Immunology 128

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Publisher : Springer Science & Business Media
ISBN 13 : 364271272X
Total Pages : 128 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Current Topics in Microbiology and Immunology 128 by : A. Clarke

Download or read book Current Topics in Microbiology and Immunology 128 written by A. Clarke and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Negative Co-Receptors and Ligands

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Publisher : Springer Science & Business Media
ISBN 13 : 3642195458
Total Pages : 154 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Negative Co-Receptors and Ligands by : Rafi Ahmed

Download or read book Negative Co-Receptors and Ligands written by Rafi Ahmed and published by Springer Science & Business Media. This book was released on 2011-04-11 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adaptive immune responses serve as a key defense mechanism for the control of infections in vertebrates. Immune responses must be of sufficient strength to contain invading pathogens, antigen specific responses require regulatory mechanisms to ensure termination or downmodulation to avoid excessive damage to the host tissue. For both branches of the adaptive immune system, regulatory molecules i.e. coreceptors and ligands have been identified that control the signaling cascades initiated by engagement of the T cell and B cell antigen receptors. This book describes biological functions as well as molecular mechanisms of these molecules.