Current Research In Protein Chemistry

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Current Research in Protein Chemistry

Author : Villafranc
Publisher : Academic Press
ISBN 13 : 0323137768
Total Pages : 635 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Current Research in Protein Chemistry by : Villafranc

Download or read book Current Research in Protein Chemistry written by Villafranc and published by Academic Press. This book was released on 1990-04-28 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Research in Protein Chemistry: Techniques, Structure, and Function reviews new techniques and methods for determining the structure and function of proteins. Topics covered include protein folding and stability, chimeric proteins, amino acid and peptide analysis, mass spectrometric methods, and protein sequencing techniques. This book is divided into six sections comprised of 55 chapters. The discussion begins with a description of microwave irradiation that uses Teflon-Pyrex tubes for protein hydrolysis, followed by the application of high performance capillary electrophoresis to the analysis of amino acids. The sections that follow explore mass spectrometry, protein sequencing, and capillary electrophoresis as well as protein stability, chimeric proteins and enzyme modifications, and protein structure prediction. Chapters focus on the crystal structure of human interleukin-1a, the acid-denatured states of proteins, solubility of recombinant proteins expressed in Escherichia coli, and catalysis by chimeric proteins. This book will be of value to students and researchers interested in protein chemistry.

Current Research in Protein Chemistry

Author : Villafranc
Publisher : Elsevier
ISBN 13 : 0323139442
Total Pages : 635 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Current Research in Protein Chemistry by : Villafranc

Download or read book Current Research in Protein Chemistry written by Villafranc and published by Elsevier. This book was released on 2012-12-02 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Research in Protein Chemistry: Techniques, Structure, and Function focuses on the techniques and methods used for determining the structure and function of proteins. Topics covered range from protein folding and stability to catalysis by chimeric proteins, amino acid and peptide analysis, applications of mass spectrometry to peptide and protein analysis, and protein sequencing. This book is divided into six sections encompassing 55 chapters. The first chapter describes a novel method for protein hydrolysis by means of microwave irradiation that uses Teflon-Pyrex tubes. This is followed by a discussion of the application of high performance capillary electrophoresis to the analysis of amino acids. The sections that follow focus on mass spectrometric methods, protein sequencing, and capillary electrophoresis as well as protein stability, chimeric proteins and enzyme modifications, and protein structure prediction. The crystal structure of human interleukin-1alpha, the acid-denatured states of proteins, solubility of recombinant proteins expressed in Escherichia coli, and catalysis by chimeric proteins are considered. The reader is also introduced to peptide mapping and internal sequencing of proteins from acrylamide gels, new approaches to covalent sequence analysis, alkaline denaturation of hemoglobin, and measurements of disulfide bond stabilities in protein folding intermediates. Students and researchers interested in protein chemistry will find this book extremely helpful.

Modern Protein Chemistry

Author : Gary C. Howard
Publisher : CRC Press
ISBN 13 : 1420036521
Total Pages : 272 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Modern Protein Chemistry by : Gary C. Howard

Download or read book Modern Protein Chemistry written by Gary C. Howard and published by CRC Press. This book was released on 2001-09-12 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, interest in proteins has surged. This resurgence has been driven by the expansion of the post-genomic era when structural genomics and proteomics require new techniques in protein chemistry and new applications of older techniques. Protein chemistry methods are used by nearly every discipline of biomedical research. Many techniques

Computational Protein Design

Author : Ilan Samish
Publisher : Humana
ISBN 13 : 9781493966356
Total Pages : 0 pages
Book Rating : 4.9/5 (663 download)

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Book Synopsis Computational Protein Design by : Ilan Samish

Download or read book Computational Protein Design written by Ilan Samish and published by Humana. This book was released on 2016-12-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim this volume is to present the methods, challenges, software, and applications of this widespread and yet still evolving and maturing field. Computational Protein Design, the first book with this title, guides readers through computational protein design approaches, software and tailored solutions to specific case-study targets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Protein Design aims to ensure successful results in the further study of this vital field.

Current Protocols in Protein Science

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (95 download)

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Book Synopsis Current Protocols in Protein Science by :

Download or read book Current Protocols in Protein Science written by and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protein Degradation with New Chemical Modalities

Author : Hilmar Weinmann
Publisher : Royal Society of Chemistry
ISBN 13 : 1839160772
Total Pages : 382 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Protein Degradation with New Chemical Modalities by : Hilmar Weinmann

Download or read book Protein Degradation with New Chemical Modalities written by Hilmar Weinmann and published by Royal Society of Chemistry. This book was released on 2020-10-07 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeting protein degradation using small molecules is one of the most exciting small-molecule therapeutic strategies in decades and a rapidly growing area of research. In particular, the development of proteolysis targeting chimera (PROTACs) as potential drugs capable of recruiting target proteins to the cellular quality control machinery for elimination has opened new avenues to address traditionally ‘difficult to target’ proteins. This book provides a comprehensive overview from the leading academic and industrial experts on recent developments, scope and limitations in this dynamically growing research area; an ideal reference work for researchers in drug discovery and chemical biology as well as advanced students.

Structure in Protein Chemistry

Author : Jack Kyte
Publisher : Garland Science
ISBN 13 : 1136843515
Total Pages : 832 pages
Book Rating : 4.1/5 (368 download)

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Book Synopsis Structure in Protein Chemistry by : Jack Kyte

Download or read book Structure in Protein Chemistry written by Jack Kyte and published by Garland Science. This book was released on 2006-11-01 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Structure in Protein Chemistry showcases the latest developments and innovations in the field of protein structure analysis and prediction. The book begins by explaining how proteins are purified and describes methods for elucidating their sequences of amino acids and defining their posttranslational modifications. Comprehensive explanations of crystallography and of noncovalent forces-ionic interactions, hydrogen bonding, and the hydrophobic effect-act as a prelude to an exhaustive description of the atomic details of the structures of proteins. The resulting understanding of protein molecular structure forms the basis for discussions of the evolution of proteins, the symmetry of the oligomeric associations that produce them, and the chemical, mathematical, and physical basis of the techniques used to study their structures. The latter include image reconstruction, nuclear magnetic resonance spectroscopy, proton exchange, optical spectroscopy, electrophoresis, covalent cross-linking, chemical modification, immunochemistry, hydrodynamics, and the scattering of light, X-radiation, and neutrons. These procedures are applied to study the folding of polypeptides and the assembly of oligomers. Biological membranes and their proteins are also discussed. Structure in Protein Chemistry, Second Edition, bridges the gap between introductory biophysical chemistry courses and research literature. It serves as a comprehensive textbook for advanced undergraduates and graduate students in biochemistry, biophysics, and structural and molecular biology. Professionals engaged in chemical, biochemical, and molecular biological research will find it a useful reference.

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protein Chemistry

Author : Nigel Stokes
Publisher :
ISBN 13 : 9781682865965
Total Pages : 223 pages
Book Rating : 4.8/5 (659 download)

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Book Synopsis Protein Chemistry by : Nigel Stokes

Download or read book Protein Chemistry written by Nigel Stokes and published by . This book was released on 2018-05-21 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins are organic compounds which are formed of amino acids that are linked together by peptides. They help the body in getting nitrogen, vitamins and sulfur. Proteins are three dimensional in their structure. Their structure can be categorized into four distinctive aspects - primary structure, secondary structure, quaternary structure and tertiary structure. As this subject is emerging at a rapid pace, the contents of this book will help the readers understand the modern concepts and applications of the subject. This book is meant for students who are looking for an elaborate reference text on protein chemistry.

Supramolecular Protein Chemistry

Author : Peter B Crowley
Publisher : Royal Society of Chemistry
ISBN 13 : 1788019806
Total Pages : 329 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Supramolecular Protein Chemistry by : Peter B Crowley

Download or read book Supramolecular Protein Chemistry written by Peter B Crowley and published by Royal Society of Chemistry. This book was released on 2020-12-09 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building on decades of “host-guest” research, recent years have seen a surge of activity in water-soluble supramolecular receptors for protein recognition and assembly. Progress has been particularly rich in the area of calixarenes, cucurbiturils and molecular tweezers. Emerging applications include controlled protein assembly in solution, crystal engineering, supramolecular control of catalysis (both in vitro and in vivo), as well as novel mechanisms of protein-interaction inhibition with relevance to amyloids and disease. One challenge at the interface of supramolecular chemistry and protein science is to increase interaction and collaboration between chemists and biochemists/structural biologists.This book addresses the exciting interface of supramolecular chemistry and protein science. Chapters cover supramolecular approaches to protein recognition, assembly and regulation. Principles outlined will highlight the opportunities that are readily accessible to collaborating chemists and biochemists, enriching the breadth and scope of this multidisciplinary field. Supramolecular Protein Chemistry will be of particular interest to graduate students and researchers working in supramolecular chemistry, protein science, self-assembly, biomaterials, biomedicine and biotechnology.

Fibrous Proteins: Amyloids, Prions and Beta Proteins

Author : John M. Squire
Publisher : Elsevier
ISBN 13 : 0080468950
Total Pages : 329 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Fibrous Proteins: Amyloids, Prions and Beta Proteins by : John M. Squire

Download or read book Fibrous Proteins: Amyloids, Prions and Beta Proteins written by John M. Squire and published by Elsevier. This book was released on 2006-12-12 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amyloids, Prions and Beta Proteins is the last volume of the three-part thematic series on Fibrous Proteins in the Advances in Protein Chemistry serial. Fibrous proteins act as molecular scaffolds in cells providing the supporting structures of our skeletons, bones, tendons, cartilage, and skin. They define the mechanical properties of our internal hollow organs such as the intestines, heart, and blood vessels. This volume covers such topics as Beta-Structures in Fibrous Proteins; B-Silks: Enhancing and Controlling Aggregation; Beta-Rolls, Beta-Helices and Other Beta-Solenoid Proteins; Natural Triple B-Stranded Fibrous Folds; Structure, Function and Amyloidogenesis of Fungal Prions: Filament Polymorphism and Prion Variants; X-Ray Fiber and powder Diffraction of PRP Prion Peptides; From the Polymorphism of Amyloid Fibrils to Their Assembly Mechanism and Cytotoxicity; Structural Models of Amyloid-like Fibrils.

Current Protocols in Chemical Biology

Author : Adam P. Arkin
Publisher : Wiley-Blackwell
ISBN 13 : 9780470559260
Total Pages : 0 pages
Book Rating : 4.5/5 (592 download)

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Book Synopsis Current Protocols in Chemical Biology by : Adam P. Arkin

Download or read book Current Protocols in Chemical Biology written by Adam P. Arkin and published by Wiley-Blackwell. This book was released on 2009-09-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Protein Molecular and Structural Biology Methods

Author : Timir Tripathi
Publisher : Academic Press
ISBN 13 : 0323902650
Total Pages : 716 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Advances in Protein Molecular and Structural Biology Methods by : Timir Tripathi

Download or read book Advances in Protein Molecular and Structural Biology Methods written by Timir Tripathi and published by Academic Press. This book was released on 2022-01-14 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application. - Presents a thorough overview of the latest and emerging methods and technologies for protein study - Explores biophysical techniques, including nuclear magnetic resonance, X-ray crystallography, and cryo-electron microscopy - Includes computational and machine learning methods - Features a section dedicated to tools and techniques specific to studying intrinsically disordered proteins

Methods in Molecular Biology and Protein Chemistry

Author : Brenda D. Spangler
Publisher : Wiley
ISBN 13 : 9780470843604
Total Pages : 232 pages
Book Rating : 4.8/5 (436 download)

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Book Synopsis Methods in Molecular Biology and Protein Chemistry by : Brenda D. Spangler

Download or read book Methods in Molecular Biology and Protein Chemistry written by Brenda D. Spangler and published by Wiley. This book was released on 2002-06-14 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ein praxisorientierter Leitfaden für Studenten im Hauptstudium. Vermittelt werden aktuelle Techniken der Molekularbiologie und Biochemie als fester Bestandteil eines Forschungsprojektes. Auf diese Weise kann der Lernende die Auswirkung der Gentechnik anhand der praktischen Anwendung von nassanalytischen biochemischen Verfahren erkennen. Mit Computer-Tutorials für Sequenzierung, Genomik und Molekülmodellierung. Mit Tipps und Hinweisen zur Sichtung der Primärliteratur, zu mündlichen Berichten, zur Protokollierung des Labortagebuchs und zum Verfassen von Berichten. Mit einer Liste von amerikanischen und europäischen kommerziellen Anbietern von Reagenzien. Verständlich und anschaulich geschrieben. Ein unverzichtbares Lehrbuch für fortgeschrittene Studenten und Doktoranden. "Methods in Molecular Biology" ist jedoch NICHT geeignet für aktive Forscher auf der Suche nach den neuesten hochdifferenzierten Verfahren.

Protein Purification

Author : Robert K. Scopes
Publisher : Springer Science & Business Media
ISBN 13 : 1475719574
Total Pages : 342 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Protein Purification by : Robert K. Scopes

Download or read book Protein Purification written by Robert K. Scopes and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: New textbooks at alllevels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical thermodynamics are weil represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a reallack ofup-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. lt is not often easy to persuade such individuals to settime aside to help spread the knowledge they have accumu lated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases the availability of texts in active research areas should help stimulate the creation of new courses. NewYork CHARLES R. CANTOR Preface to the Second Edition The original plan for the first edition of this book was to title it Enzyme Purification: Princip/es and Practice.

Vibrational Spectroscopy in Protein Research

Author : Yukihiro Ozaki
Publisher : Academic Press
ISBN 13 : 9780128186107
Total Pages : 0 pages
Book Rating : 4.1/5 (861 download)

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Book Synopsis Vibrational Spectroscopy in Protein Research by : Yukihiro Ozaki

Download or read book Vibrational Spectroscopy in Protein Research written by Yukihiro Ozaki and published by Academic Press. This book was released on 2020-05-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vibrational Spectroscopy in Protein Research offers a thorough discussion of vibrational spectroscopy in protein research, providing researchers with clear, practical guidance on methods employed, areas of application, and modes of analysis. With chapter contributions from international leaders in the field, the book addresses basic principles of vibrational spectroscopy in protein research, instrumentation and technologies available, sampling methods, quantitative analysis, origin of group frequencies, and qualitative interpretation. In addition to discussing vibrational spectroscopy for the analysis of purified proteins, chapter authors also examine its use in studying complex protein systems, including protein aggregates, fibrous proteins, membrane proteins and protein assemblies. Emphasis throughout the book is placed on applications in human tissue, cell development, and disease analysis, with chapters dedicated to studies of molecular changes that occur during disease progression, as well as identifying changes in tissues and cells in disease studies.

Methods in Protein Biochemistry

Author : Harald Tschesche
Publisher : Walter de Gruyter
ISBN 13 : 3110252368
Total Pages : 379 pages
Book Rating : 4.1/5 (12 download)

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Book Synopsis Methods in Protein Biochemistry by : Harald Tschesche

Download or read book Methods in Protein Biochemistry written by Harald Tschesche and published by Walter de Gruyter. This book was released on 2011-12-23 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a survey of recent developments in protein biochemistry. Top researchers in the field of protein biochemistry describe modern methods to address the challenges of protein purification by three-phase partitioning, and their folding and degradation by the functions of chaperones. The significance of peptide purity for fibril formation is addressed as well as the use of target oriented peptide arrays in palliative approaches in mucoviszidose. The design and application of protein epitope mimetics just as the structural resolving of the misfolding of various mutant proteins in serpinopathies enlarge our tools in resolving pathophysiological imbalances.