Current Protocols In Neuroscience Supplement 30

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Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 030916785X
Total Pages : 223 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research by : National Research Council

Download or read book Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2003-08-22 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.

Life's rewards

Author : Richard J. Beninger
Publisher : Oxford University Press
ISBN 13 : 0192557386
Total Pages : 769 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis Life's rewards by : Richard J. Beninger

Download or read book Life's rewards written by Richard J. Beninger and published by Oxford University Press. This book was released on 2018-07-18 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its discovery in the 1960s, a vast and wide-ranging body of research has accumulated about the dopaminergic system. Life's Rewards: Linking Dopamine, Incentive Learning, Schizophrenia, and the Mind offers a broad synthesis of our current understanding of this chemical, addressing, amongst others, its intricate relationship with learning and memory, psychopathology, social co-operation, and drug abuse. Aimed at students and researchers in neuroscience and psychology, Life's Rewards: Linking Dopamine, Incentive Learning, Schizophrenia, and the Mind is essential reading for anyone interested in the relationship between dopamine and reward-related incentive learning.

Guide to Research Techniques in Neuroscience

Author : Matt Carter
Publisher : Academic Press
ISBN 13 : 0323915612
Total Pages : 416 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Guide to Research Techniques in Neuroscience by : Matt Carter

Download or read book Guide to Research Techniques in Neuroscience written by Matt Carter and published by Academic Press. This book was released on 2022-03-26 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - "Walk-through" boxes that guide readers through experiments step-by-step

Advanced Imaging Methods in Neuroscience

Author : João O. Malva
Publisher : Frontiers Media SA
ISBN 13 : 2889717259
Total Pages : 498 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Advanced Imaging Methods in Neuroscience by : João O. Malva

Download or read book Advanced Imaging Methods in Neuroscience written by João O. Malva and published by Frontiers Media SA. This book was released on 2022-01-11 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Encyclopedia of Sleep

Author :
Publisher : Academic Press
ISBN 13 : 0123786118
Total Pages : 2626 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Encyclopedia of Sleep by :

Download or read book Encyclopedia of Sleep written by and published by Academic Press. This book was released on 2013-01-17 with total page 2626 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a world of 24-hour media saturation, sleep has become an increasingly fraught enterprise. The award-winning four-volume Encyclopedia of Sleep, Four Volume Set is the largest reference, either online or in print, on the subject of sleep. Written to be useful for the novice and the established researcher and clinician, Topic areas will include sleep across the life cycle and in other species, sleep and women, sleep and the elderly, pediatric sleep, sleep deprivation and loss, sleep mechanisms, sleep physiology and pathophysiology, sleep disorders, neurobiology, chronobiology, pharmacology, and impact of other disorders on sleep. Recognizing the many fields that are connected to sleep science, the editorial team has been carefully chosen to do justice to this highly interdisciplinary field of study. The steady growth of researchers and clinicians in the sleep field attests to the continued interest in the scientific study of sleep and the management of patients with sleep disorders, and anyone involved in this exciting field should find this work to be an invaluable reference. 2013 PROSE Award winner for Multivolume Reference in Science from the Association of American Publishers Thoroughly interdisciplinary: looks at sleep throughout the life cycle, with exceptional coverage of basic sleep concepts, the physiology of sleep as well as sleep disorders of all descriptions Excellent coverage of sleep and special populations, covering the lifespan, as well as gender and ethnic differences, among others Chapters focusing on sleep disorders are grouped under the broad categories classified in the ICSD-2 for clear organization so that the reader can effectively access the steps involved in diagnosing and treating these disorders Online version is linked both within the encyclopedia (to related content) and to external sources (such as primary journal content) so that users have easy access to more detailed information if needed

Herbal Supplements and the Brain

Author : S.J. Enna
Publisher : FT Press
ISBN 13 : 0132825015
Total Pages : 273 pages
Book Rating : 4.1/5 (328 download)

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Book Synopsis Herbal Supplements and the Brain by : S.J. Enna

Download or read book Herbal Supplements and the Brain written by S.J. Enna and published by FT Press. This book was released on 2012-05-07 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, many manufacturers of plant-based "neuroceuticals" claim their products can offer powerful benefits in brain function. However, the US government does not require these manufacturers to demonstrate their products’ effectiveness, leaving it difficult for consumers and health professionals to make decisions about the benefits and risks. In Herbal Supplements and the Brain: Understanding their Health Benefits and Hazards, two leading researchers provide this crucial information in clear language any intelligent reader can understand and use. They begin by introducing the fundamental principles of pharmacology, explaining how drugs and natural products can affect the body’s organs and organ systems. Using examples, they show how to determine whether an ingested substance can enter the bloodstream and reach its target at a concentration sufficient to have an effect. They also explain how natural products may influence blood levels of other substances, and discuss whether such interactions may diminish the effectiveness of prescription medications or alter normal body chemistry. Throughout, the authors emphasize factors relating especially to neuroceuticals and the brain. Individual chapters are devoted to nutritional supplements which promise to enhance memory, relieve pain, safely promote sleep, and aid in the treatment of depression or anxiety. Specifically, readers will find research-based coverage of Ginkgo biloba; St. John’s Wort; Valerian; Lemon Balm; Kava; Lavender; Kudzu, Daffodil, Passion Flower, and Camellia Tea and other caffeinated beverages.

Psychology

Author : Graham C. Davey
Publisher : John Wiley & Sons
ISBN 13 : 1119465796
Total Pages : 1080 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Psychology by : Graham C. Davey

Download or read book Psychology written by Graham C. Davey and published by John Wiley & Sons. This book was released on 2018-12-17 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychology continues to be one of the most popular fields of study at colleges and universities the world over, and Psychology offers a comprehensive overview of the historical, methodological, and conceptual core of modern psychology. This textbook enables students to gain foundational knowledge of psychological investigation, exploring both the biological basis and mental processes underlying our thoughts and behaviours. Officially endorsed by the British Psychological Society, this book covers topics ranging from biological, cognitive and developmental psychology to the psychology of social interactions, psychopathology and mental health treatments. Each chapter provides detailed examination of essential topics, chapter summaries, real-world case studies, descriptions of research methods, and interactive learning activities to strengthen student comprehension and retention. This textbook offers a wealth of supplementary material for instructors of introductory and advanced undergraduate courses in psychology. An instructor's manual includes lecture outlines, classroom discussion topics, homework assignments and test bank questions, while online access to additional digital content provides a complete resource to facilitate effective teaching and learning.

Anxious

Author : Joseph LeDoux
Publisher : Penguin
ISBN 13 : 0143109049
Total Pages : 482 pages
Book Rating : 4.1/5 (431 download)

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Book Synopsis Anxious by : Joseph LeDoux

Download or read book Anxious written by Joseph LeDoux and published by Penguin. This book was released on 2016-08-23 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: “A rigorous, in-depth guide to the history, philosophy, and scientific exploration of this widespread emotional state . . . [LeDoux] offers a magisterial review of the role of mind and brain in the generation of unconscious defense responses and consciously expressed anxiety. . . . [His] charming personal asides give an impression of having a conversation with a world expert.” —Nature A comprehensive and accessible exploration of anxiety, from a leading neuroscientist and the author of Synaptic Self Collectively, anxiety disorders are our most prevalent psychiatric problem, affecting about forty million adults in the United States. In Anxious, Joseph LeDoux, whose NYU lab has been at the forefront of research efforts to understand and treat fear and anxiety, explains the range of these disorders, their origins, and discoveries that can restore sufferers to normalcy. LeDoux’s groundbreaking premise is that we’ve been thinking about fear and anxiety in the wrong way. These are not innate states waiting to be unleashed from the brain, but experiences that we assemble cognitively. Treatment of these problems must address both their conscious manifestations and underlying non-conscious processes. While knowledge about how the brain works will help us discover new drugs, LeDoux argues that the greatest breakthroughs may come from using brain research to help reshape psychotherapy. A major work on one of our most pressing mental health issues, Anxious explains the science behind fear and anxiety disorders. Praise for Anxious: “[Anxious] helps to explain and prevent the kinds of debilitating anxieties all of us face in this increasingly stressful world.” —Daniel J. Levitin, author of The Organized Mind and This Is Your Brain on Music “A careful tour through the current neuroscience of fear and anxiety . . . [Anxious] will reward the informed reader.” —The Wall Street Journal “An extraordinarily ambitious, provocative, challenging, and important book. Drawing on the latest research in neuroscience (including work in his own laboratory), LeDoux provides explanations of the origins, nature, and impact of fear and anxiety disorders.” —Psychology Today

Current Protocols in Neuroscience

Author : Jacqueline N. Crawley
Publisher : Current Protocols
ISBN 13 : 9780471163619
Total Pages : pages
Book Rating : 4.1/5 (636 download)

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Book Synopsis Current Protocols in Neuroscience by : Jacqueline N. Crawley

Download or read book Current Protocols in Neuroscience written by Jacqueline N. Crawley and published by Current Protocols. This book was released on 1997-06-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Protocols in Neuroscience (CPN) draws from techniques in molecular neurobiology, neurophysiology, neuroanatomy, neuropharmacology, and behavioral neuroscience to meet the specific needs of researchers in the full range of disciplines that is involved in studying the brain, nervous system, and corresponding behaviors. The editorial board of CPN have assembled an outstanding range of methods to enable users to explore their fields in greater depth and branch into related areas. The one-volume, looseleaf manual features carefully edited techniques with authors' troubleshooting tips and helpful comments that come from extensive experience in using these procedures. Quarterly updates, filed into the looseleaf, keep you and your laboratory current with the latest developments in this rapidly changing field. The initial purchase includes one year of updates and then subscribers may renew their annual subscriptions. Current Protocols publishes a family of laboratory manuals for bioscientists, including Molecular Biology, Immunology, Human Genetics, Protein Science, Cytometry, Cell Biology, Pharmacology, and Toxicology.

Understanding Light Microscopy

Author : Jeremy Sanderson
Publisher : John Wiley & Sons
ISBN 13 : 1118696743
Total Pages : 851 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Understanding Light Microscopy by : Jeremy Sanderson

Download or read book Understanding Light Microscopy written by Jeremy Sanderson and published by John Wiley & Sons. This book was released on 2019-03-04 with total page 851 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces readers to the enlightening world of the modern light microscope There have been rapid advances in science and technology over the last decade, and the light microscope, together with the information that it gives about the image, has changed too. Yet the fundamental principles of setting up and using a microscope rests upon unchanging physical principles that have been understood for years. This informative, practical, full-colour guide fills the gap between specialised edited texts on detailed research topics, and introductory books, which concentrate on an optical approach to the light microscope. It also provides comprehensive coverage of confocal microscopy, which has revolutionised light microscopy over the last few decades. Written to help the reader understand, set up, and use the often very expensive and complex modern research light microscope properly, Understanding Light Microscopy keeps mathematical formulae to a minimum—containing and explaining them within boxes in the text. Chapters provide in-depth coverage of basic microscope optics and design; ergonomics; illumination; diffraction and image formation; reflected-light, polarised-light, and fluorescence microscopy; deconvolution; TIRF microscopy; FRAP & FRET; super-resolution techniques; biological and materials specimen preparation; and more. Gives a didactic introduction to the light microscope Encourages readers to use advanced fluorescence and confocal microscopes within a research institute or core microscopy facility Features full-colour illustrations and workable practical protocols Understanding Light Microscopy is intended for any scientist who wishes to understand and use a modern light microscope. It is also ideal as supporting material for a formal taught course, or for individual students to learn the key aspects of light microscopy through their own study.

Patch Clamping

Author : Areles Molleman
Publisher : John Wiley & Sons
ISBN 13 : 0470856513
Total Pages : 186 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Patch Clamping by : Areles Molleman

Download or read book Patch Clamping written by Areles Molleman and published by John Wiley & Sons. This book was released on 2003-06-13 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patch clamping is a widely applied electrophysiological technique for the study of ion channels; membrane proteins that regulate the flow of ions across cellular membranes and therefore influence the physiology of all cells. Patch Clamping aims to cover the basic principles and practical applications of this important technique. Starting with a review of the history of patch clamping, the text then goes on to cover the basic principles, platforms, equipment and environmental control, and will also include coverage of preparation types, recording modes and analysis of results. This book will explain the basic principles and practical application of patch clamp electrophysiology Written in a non-technical style to ensure its broad appeal to novice users Takes a practical approach This self-contained guide provides everything a practising patch clamp electrophysiologist needs to know to master this technique, including an overview of membrane biophysics, standard experimental design, data analysis, and technical concerns

Current Protocols in Molecular Biology

Author :
Publisher :
ISBN 13 : 9780471163619
Total Pages : pages
Book Rating : 4.1/5 (636 download)

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Book Synopsis Current Protocols in Molecular Biology by :

Download or read book Current Protocols in Molecular Biology written by and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neuroscience Year: Supplement 1 to the Encyclopedia of Neuroscience

Author : George Adelman
Publisher : Birkhäuser
ISBN 13 : 9780817633837
Total Pages : 212 pages
Book Rating : 4.6/5 (338 download)

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Book Synopsis Neuroscience Year: Supplement 1 to the Encyclopedia of Neuroscience by : George Adelman

Download or read book Neuroscience Year: Supplement 1 to the Encyclopedia of Neuroscience written by George Adelman and published by Birkhäuser. This book was released on 1989-01-01 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Current Protocols in Immunology

Author : John E. Coligan
Publisher : Current Protocols
ISBN 13 :
Total Pages : 846 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Current Protocols in Immunology by : John E. Coligan

Download or read book Current Protocols in Immunology written by John E. Coligan and published by Current Protocols. This book was released on 1991 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Protocols in Immunology is a three-volume looseleaf manual that provides comprehensive coverage of immunological methods from classic to the most cutting edge, including antibody detection and preparation, assays for functional activities of mouse and human cells involved in immune responses, assays for cytokines and their receptors, isolation and analysis of proteins and peptides, biochemistry of cell activation, molecular immunology, and animal models of autoimmune and inflammatory diseases. Carefully edited, step-by-step protocols replete with material lists, expert commentaries, and safety and troubleshooting tips ensure that you can duplicate the experimental results in your own laboratory. Bimonthly updates, which are filed into the looseleaf, keep the set current with the latest developments in immunology methods. The initial purchase includes one year of updates and then subscribers may renew their annual subscriptions. Current Protocols publishes a family of laboratory manuals for bioscientists, including Molecular Biology, Human Genetics, Protein Science, Cytometry, Cell Biology, Neuroscience, Pharmacology, and Toxicology.

Neuroscience Year

Author : Adelman
Publisher : Birkhäuser
ISBN 13 : 9780817635923
Total Pages : 216 pages
Book Rating : 4.6/5 (359 download)

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Book Synopsis Neuroscience Year by : Adelman

Download or read book Neuroscience Year written by Adelman and published by Birkhäuser. This book was released on 1993-09-21 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cochlear Neuron and Ribbon Synapse: Development, Degeneration, Repair and Regeneration

Author : Tejbeer Kaur
Publisher : Frontiers Media SA
ISBN 13 : 2889746828
Total Pages : 246 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Cochlear Neuron and Ribbon Synapse: Development, Degeneration, Repair and Regeneration by : Tejbeer Kaur

Download or read book Cochlear Neuron and Ribbon Synapse: Development, Degeneration, Repair and Regeneration written by Tejbeer Kaur and published by Frontiers Media SA. This book was released on 2022-11-02 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Surgically Treated Intracerebral Haemorrhage

Author : Lovisa Tobieson
Publisher : Linköping University Electronic Press
ISBN 13 : 9176851273
Total Pages : 131 pages
Book Rating : 4.1/5 (768 download)

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Book Synopsis Surgically Treated Intracerebral Haemorrhage by : Lovisa Tobieson

Download or read book Surgically Treated Intracerebral Haemorrhage written by Lovisa Tobieson and published by Linköping University Electronic Press. This book was released on 2019-04-17 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mortality and morbidity of intracerebral haemorrhage (ICH) is excessively high, and the case fatality rate has not improved in the last decades. Although surgery for ICH can be life-saving, no positive effect on functional outcome has been found in large cohorts of ICH patients. Increased understanding of the pathophysiology of ICH is needed to develop improved treatment strategies. In 17 ICH patients, paired cerebral microdialysis (CMD) catheters were inserted in the perihaemorrhagic zone (PHZ) and in normal uninjured cortex at time of surgery. Despite normalisation of cerebral blood flow, a persistent metabolic crisis indicative of mitochondrial dysfunction was detected in the PHZ. This metabolic pattern was not observed in the uninjured cortex. CMD was also used to sample proteins for proteomic analysis. A distinct proteome profile that changed over time was found in the PHZ when compared to the seemingly normal, uninjured cortex. However, protein adsorption to CMD membranes, which may interfere with concentration measurements, was substantial. Surgical treatment of 578 ICH patients was analysed in a nation-wide retrospective multi-centre study in Sweden over five years. Patients selected for surgery had similar age, pre-operative level of consciousness and co-morbidity profiles, but ICH volume and the proportion of deep-seated ICH differed among the six neurosurgical centres. Furthermore, there was variability in the post-operative care, including the use and duration of intracranial pressure monitoring, cerebrospinal fluid drainage and mechanical ventilation. In conclusion, the results of this thesis show that: (i) Despite surgical removal of an ICH a metabolic crisis caused by mitochondrial dysfunction, a potential future therapeutic target, persists in the perihaemorrhagic zone. (ii-iii) CMD is a valuable tool in ICH research for sampling novel biomarkers using proteomics, which may aid in the development of improved therapeutic interventions. However, caveats of the technique, such as protein adsorption to the CMD membrane, must be considered. (iv) The nation-wide study illustrates similar clinical features in patients selected for ICH surgery, but substantial variability in ICH volume and location as well as neurocritical care strategies among Swedish neurosurgical centres. Development of refined clinical guidelines may reduce such intercentre variability and lead to improved functional outcome for ICH patients.