Culture Negative Orthopedic Biofilm Infections

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Publisher : Springer Science & Business Media
ISBN 13 : 3642295541
Total Pages : 148 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Culture Negative Orthopedic Biofilm Infections by : Garth D. Ehrlich

Download or read book Culture Negative Orthopedic Biofilm Infections written by Garth D. Ehrlich and published by Springer Science & Business Media. This book was released on 2012-12-18 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the recent transition between acute diseases caused by swarms of single planktonic bacteria, and chronic infections caused by bacteria growing in slime-enclosed biofilms, a general clinical consensus has emerged that pathologies with bacterial etiologies are frequently culture negative. Because biofilm infections now affect 17 million Americans per year (killing approximately 450,000), the suggestion that these common and lethal infections regularly go unnoticed by the only FDA-approved method for their detection and characterization is a matter of urgent concern. Biologically, we would expect that planktonic bacterial cells would colonize any new surface, including the surface of an agar plate, while the specialized sessile cells of a biofilm community would have no such proclivity. In the study of biofilm diseases ranging from otitis media to prostatitis, it was found that direct microscopy and DNA- and RNA-based molecular methods regularly document the presence of living bacteria in tissues and samples that are culture negative. The editors selected orthopedic biofilm infections as the subject of this book because these infections occur against a background of microbiological sterility in which modern molecular methods would be expected to find bacterial DNA, RNA-based microscopic methods would be expected to locate bacterial cells, and cultures would be negative. Moreover, in Orthopedics we find an already biofilm-adapted surgical group in which current strategies are based on the meticulous removal of compromised tissues, antibiotic options as based on high biofilm-killing local doses, and there are practical bedside strategies for dealing with biofilm infections. So here is where the new paradigm of biofilm infection meets the equally new paradigm of the culture negativity of biofilms, and this volume presents a conceptual synthesis that may soon combine the most effective molecular methods for the detection and identification of bacteria with a surgical discipline that is ready to help patients.

Biofilm Infections

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Publisher : Springer
ISBN 13 : 9781489982285
Total Pages : 0 pages
Book Rating : 4.9/5 (822 download)

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Book Synopsis Biofilm Infections by : Thomas Bjarnsholt

Download or read book Biofilm Infections written by Thomas Bjarnsholt and published by Springer. This book was released on 2014-10-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.

Prosthetic Joint Infections

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Publisher : Springer
ISBN 13 : 3319652508
Total Pages : 270 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Prosthetic Joint Infections by : Trisha Peel

Download or read book Prosthetic Joint Infections written by Trisha Peel and published by Springer. This book was released on 2017-11-28 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book outlines the most updated clinical guidelines that are vital for the prevention infections and care of patients with joint infections following a replacement surgery, one of the highest volume medical interventions globally. Sections address the diagnosis, management approaches and prevention of prosthetic joint infections. Written by experts in the field, this text provides a brief overview of the literature and current recommendations in each of the specified areas. Given the rapidly evolving state-of-play in this clinical area, this compendium grows increasingly important to clinicians in their management decisions. Prosthetic Joint Infections is a valuable resource for infectious disease specialists, epidemiologists, surgeons, and orthopedic specialists who may work with patients with prosthetic joint infections.

Biofilms, Infection, and Antimicrobial Therapy

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Author :
Publisher : CRC Press
ISBN 13 : 1420028235
Total Pages : 520 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Biofilms, Infection, and Antimicrobial Therapy by : John L. Pace

Download or read book Biofilms, Infection, and Antimicrobial Therapy written by John L. Pace and published by CRC Press. This book was released on 2005-08-29 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rather than existing in a planktonic or free-living form, evidence indicates that microbes show a preference for living in a sessile form within complex communities called biofilms. Biofilms appear to afford microbes a survival advantage by optimizing nutrition, offering protection against hostile elements, and providing a network for cell-to-cell

Management of Orthopaedic Infections

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Author :
Publisher : Thieme
ISBN 13 : 1638536686
Total Pages : 350 pages
Book Rating : 4.6/5 (385 download)

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Book Synopsis Management of Orthopaedic Infections by : Antonia Chen

Download or read book Management of Orthopaedic Infections written by Antonia Chen and published by Thieme. This book was released on 2021-04-22 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: An evidence-based resource for effectively managing challenging orthopaedic infections Orthopaedic infections represent common, potentially devastating, and sometimes fatal complications that can occur after any surgery. Infections associated with orthopaedic trauma are especially prevalent, and there is an increasing incidence of bone infections linked to a greater number of joint arthroplasties being performed annually. Management of Orthopaedic Infections: A Practical Guide by renowned orthopaedic surgeon and researcher Antonia Chen is a practical clinical reference to assist clinicians in the diagnosis and treatment of challenging infections spanning the entire orthopaedic specialty. The step-by-step guide covers frequent organisms found in orthopaedics, molecular methods to improve organism determination, different antibiotic formulations to treat infections, various irrigation solutions used during surgery, and surgical dressings. Ten concise chapters cover surgical management of common infectious pathologies, including osteomyelitis, septic joint, periprosthetic joint infection, open fractures and infected nonunions, spine infections, and graft infections. Key Features High-quality figures and instructional surgical videos illustrate and enhance understanding of important concepts Multiple tables provide quick references and easy access to salient information needed to manage the care of patients with orthopaedic infections Practical tips from clinicians with vast expertise inform optimal treatment strategies and enable improved outcomes This is a must-have pocket resource for medical students, residents, fellows, and practitioners in orthopaedic surgery, as well as allied health personnel.

Medical Biofilms

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Publisher : John Wiley & Sons
ISBN 13 : 9780471988670
Total Pages : 328 pages
Book Rating : 4.9/5 (886 download)

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Book Synopsis Medical Biofilms by : Jana Jass

Download or read book Medical Biofilms written by Jana Jass and published by John Wiley & Sons. This book was released on 2003-04-02 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms are formed by microorganisms growing on surfaces and comprise a series of microcolonies interspersed with spaces through which fluids and other microorganisms move. In medicine, the primary problems are biofilms associated with implants: infections are increasingly difficult to treat with traditional antibiotics and removal of the implant often becomes essential, frequently leading to higher morbidity and mortality. This will be the first book dedicated to medical biofilms. It will cover much recent information on the problems of biofilms, how to detect them and how to control their presence.

Bone and Joint Infections

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Publisher : John Wiley & Sons
ISBN 13 : 1118581776
Total Pages : 429 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Bone and Joint Infections by : W. Zimmerli

Download or read book Bone and Joint Infections written by W. Zimmerli and published by John Wiley & Sons. This book was released on 2015-01-27 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infections of the bones (osteomyelitis) and joints (septic arthritis) are serious health problems which require antibiotics and often surgery. Awareness among health professionals of the causes and treatment options for various types of bone and joint infections is essential for effective resolution. Bone and Joint Infections takes a multidisciplinary approach in covering the diagnostic and therapeutic treatment of osteomyelitis and septic arthritis, including different types of implant-associated infections. Correct and rapid diagnosis of bone and joint infection is crucial, and requires the input of a variety of specialists. Bone and Joint Infection takes a similarly collaborative and comprehensive approach, including chapters authored by clinicians, laboratory specialists, and surgeons. Covering the basic microbiology and clinical aspects of bone and joint infection, this book will be a valuable resource both for researchers in the lab and for physicians and surgeons seeking a comprehensive reference on osteomyelitis and septic arthritis.

Bacterial Biofilms

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Publisher : Springer Science & Business Media
ISBN 13 : 3540754180
Total Pages : 302 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Bacterial Biofilms by : Tony Romeo

Download or read book Bacterial Biofilms written by Tony Romeo and published by Springer Science & Business Media. This book was released on 2008-02-26 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.

Periprosthetic Joint Infection: Practical Management Guide

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Publisher : JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.
ISBN 13 : 9350908255
Total Pages : 432 pages
Book Rating : 4.3/5 (59 download)

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Book Synopsis Periprosthetic Joint Infection: Practical Management Guide by : Parvizi Javad

Download or read book Periprosthetic Joint Infection: Practical Management Guide written by Parvizi Javad and published by JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.. This book was released on 2013-12-15 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book Periprosthetic Joint Infection is a portable guide to the practical management of surgical site infections following orthopedic procedures. It designed to help answer clinician's questions regarding the prevention and treatment of periprosthetic infections. It organized for rapid review, featuring evidence reviews, pitfalls, Rothman Institute Current Practices and Controversies. The guide is being included in the course materials for the 29th Annual Current Concepts in Joint Replacement® (CCJR) meeting thanks to a generous educational grant from 3M Health Care.

Biofilm-based Healthcare-associated Infections

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Publisher : Springer
ISBN 13 : 3319110381
Total Pages : 193 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Biofilm-based Healthcare-associated Infections by : Gianfranco Donelli

Download or read book Biofilm-based Healthcare-associated Infections written by Gianfranco Donelli and published by Springer. This book was released on 2014-11-03 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide readers with a wide overview of the main healthcare-associated infections caused by bacteria and fungi able to grow as biofilm. The recently acquired knowledge on the pivotal role played by biofilm-growing microorganisms in healthcare-related infections has given a new dynamic to detection, prevention and treatment of these infections in patients admitted to both acute care hospitals and long-term care facilities. Clinicians, hygienists and microbiologists will be updated by leading scientists on the state-of-art of biofilm-based infections and on the most innovative strategies for prevention and treatment of these infections, often caused by emerging multidrug-resistant biofilm-growing microorganisms.

Orthopedic Infection

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Publisher : Springer Science & Business Media
ISBN 13 : 1461238706
Total Pages : 196 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Orthopedic Infection by : David Schlossberg

Download or read book Orthopedic Infection written by David Schlossberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, clinically oriented reference details the state-of-the-art approach to infections of bones and joints. Utility for all practitioners is ensured by the wide range of contributors who include infectious disease specialists, rheumatologists, orthopedic surgeons, and radiologists. This is the definitive resource for the clinician who treats orthopedic infections.

Coagulase-negative Staphylococci

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Author :
Publisher : Coronet Books
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Coagulase-negative Staphylococci by : Per-Anders Mårdh

Download or read book Coagulase-negative Staphylococci written by Per-Anders Mårdh and published by Coronet Books. This book was released on 1986 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Management of Periprosthetic Joint Infections (PJIs)

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Author :
Publisher : Woodhead Publishing
ISBN 13 : 0081002424
Total Pages : 306 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Management of Periprosthetic Joint Infections (PJIs) by : J.J. Chris Arts

Download or read book Management of Periprosthetic Joint Infections (PJIs) written by J.J. Chris Arts and published by Woodhead Publishing. This book was released on 2016-10-25 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Management of Periprosthetic Joint Infections (PJIs): Management of PJIs discusses periprosthetic joint infection (PJI), a fairly rare occurrence that is nonetheless one of the most serious complications in joint replacement surgery. Intricate interactions between the pathogen, the host, and the implant can result in PJIs which are not only physically devastating for the patient, but also financially crippling for health authorities and insurance companies. Actions taken to minimize the risk of PJIs can be extremely challenging for the orthopaedic community. Consequently, new research, which is detailed in this comprehensive book, is being undertaken to minimize and manage these challenging infections. Provides essential background knowledge on the mechanisms and identification of PJIs Dedicated chapters focus on the complex, but vital eccentricities between PJIs in different areas of the body Contains contributions from a mixture of clinical and academic experts in the field, thus ensuring balanced coverage

Musculoskeletal Infection

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Publisher :
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Musculoskeletal Infection by : John L. Esterhai

Download or read book Musculoskeletal Infection written by John L. Esterhai and published by . This book was released on 1992 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a guide to understanding the mechanisms involved in the pathogenesis of muscoskeletal sepsis. It covers areas such as bone, cartilage, soft tissue, and biomaterial interaction in the face of infection.

Histological Diagnosis of Implant-associated Pathologies

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Publisher : Springer
ISBN 13 : 3662542048
Total Pages : 53 pages
Book Rating : 4.6/5 (625 download)

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Book Synopsis Histological Diagnosis of Implant-associated Pathologies by : Veit Krenn

Download or read book Histological Diagnosis of Implant-associated Pathologies written by Veit Krenn and published by Springer. This book was released on 2017-05-09 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt: Histological evaluation of the periprosthetic soft and osseous tissues is an important analytical tool. Its standardization is essential to generate accurate and reproducible data which allow comparisons for academic institutions, arthroplasty registries, and government regulatory agencies worldwide. It is also part of multidisciplinary evaluation of orthopedic implant failures and provides valuable information to be integrated with the clinical data, allergological tests, radiological exams, microbiological analysis, and biomechanical assessment of the implant wear.

Bacterial Biofilms

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1789858992
Total Pages : 362 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Bacterial Biofilms by : Sadik Dincer

Download or read book Bacterial Biofilms written by Sadik Dincer and published by BoD – Books on Demand. This book was released on 2020-10-07 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines biofilms in nature. Organized into four parts, this book addresses biofilms in wastewater treatment, inhibition of biofilm formation, biofilms and infection, and ecology of biofilms. It is designed for clinicians, researchers, and industry professionals in the fields of microbiology, biotechnology, ecology, and medicine as well as graduate and postgraduate students.

Periprosthetic Joint Infections

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Author :
Publisher : Springer
ISBN 13 : 3319300911
Total Pages : 367 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Periprosthetic Joint Infections by : Daniel Kendoff

Download or read book Periprosthetic Joint Infections written by Daniel Kendoff and published by Springer. This book was released on 2016-05-31 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a state-of-the-art, worldwide overview of treatment options available for periprosthetic joint infection (PJI). It highlights areas where tremendous progress has been made over the past few years, looking at current evidence, projecting a way forward, and discussing key topics where ongoing research is needed and could potentially have a huge impact on the field. In addition to familiarising readers with effective diagnostics and treatment strategies, factors such as socioeconomics and associated morbidity are also examined in relation to this increasingly common condition. Periprosthetic Joint Infections: Changing Paradigms includes expert guidance based on the best available evidence and practice that can be applied in even the most difficult infection cases. To create this keystone resource for the orthopaedic community, the editors have brought together prominent experts from Europe and the US to give an international, authoritative perspective on this important topic. This book is an essential guide for specialists who deal with challenging cases of PJI in clinical practice or researchers who are seeking a reference point to undertake further studies in this growing area.