Copper Catalyzed Multi Component Reactions

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Copper-Catalyzed Multi-Component Reactions

Author : Yusuke Ohta
Publisher : Springer Science & Business Media
ISBN 13 : 3642154735
Total Pages : 110 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Copper-Catalyzed Multi-Component Reactions by : Yusuke Ohta

Download or read book Copper-Catalyzed Multi-Component Reactions written by Yusuke Ohta and published by Springer Science & Business Media. This book was released on 2011-01-20 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: A copper-catalyzed direct synthesis of 2-(aminomethyl)indoles by catalytic domino reaction including multi-component coupling was developed, and is the first example of a three-component indole formation without producing salts as a byproduct. Based on this reaction, a copper-catalyzed synthesis of 3-(aminomethyl)isoquinoline was accomplished which represents an unprecedented isoquinoline synthesis through a four-component coupling reaction. Following these results, extensive application studies using one-pot palladium-, acid-, or base-promoted cyclization revealed that indole- or isoquinoline-fused polycyclic compounds can be readily synthesized through multi-component reactions. As the concept of Green Chemistry becomes ever more important, these findings may provide efficient and atom-economical approaches to the diversity-oriented synthesis of bioactive compounds containing a complex structure. This could lead to development of promising drug leads with structural complexity. The work of this thesis will go on to inspire the synthetic research of many readers.

Copper-Catalyzed Multi-Component Reactions

Author : Yusuke Ohta
Publisher : Springer
ISBN 13 : 9783642154744
Total Pages : 120 pages
Book Rating : 4.1/5 (547 download)

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Book Synopsis Copper-Catalyzed Multi-Component Reactions by : Yusuke Ohta

Download or read book Copper-Catalyzed Multi-Component Reactions written by Yusuke Ohta and published by Springer. This book was released on 2011-03-30 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the concept of Green Chemistry becomes ever more important, the findings presented in this book may provide efficient and atom-economical approaches to the diversity-oriented synthesis of bioactive compounds containing a complex structure.

Copper Catalysis in Organic Synthesis

Author : Gopinathan Anilkumar
Publisher : John Wiley & Sons
ISBN 13 : 3527347372
Total Pages : 504 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Copper Catalysis in Organic Synthesis by : Gopinathan Anilkumar

Download or read book Copper Catalysis in Organic Synthesis written by Gopinathan Anilkumar and published by John Wiley & Sons. This book was released on 2020-12-07 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most current information on growing field of copper catalysis Copper Catalysis in Organic Synthesis contains an up-to-date overview of the most important reactions in the presence of copper catalysts. The contributors—noted experts on the topic—provide an introduction to the field of copper catalysis, reviewing its development, scope, and limitations, as well as providing descriptions of various homo- and cross-coupling reactions. In addition, information is presented on copper-catalyzed C–H activation, amination, carbonylation, trifluoromethylation, cyanation, and click reactions. Comprehensive in scope, the book also describes microwave-assisted and multi-component transformations as well as copper-catalyzed reactions in green solvents and continuous flow reactors. The authors highlight the application of copper catalysis in asymmetric synthesis and total synthesis of natural products and heterocycles as well as nanocatalysis. This important book: Examines copper and its use in organic synthesis as a more cost-effective and sustainable for researchers in academia and industry Offers the first up-to-date book to explore copper as a first line catalyst for many organic reactions Presents the most significant developments in the area, including cross-coupling reactions, C–H activation, asymmetric synthesis, and total synthesis of natural products and heterocycles Contains over 20 contributions from leaders in the field Written for catalytic chemists, organic chemists, natural products chemists, pharmaceutical chemists, and chemists in industry, Copper Catalysis in Organic Synthesis offers a book on the growing field of copper catalysis, covering cross-coupling reactions, C–H activation, and applications in the total synthesis of natural products.

Efficiency in Natural Product Total Synthesis

Author : Pei-Qiang Huang
Publisher : John Wiley & Sons
ISBN 13 : 1118940210
Total Pages : 512 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Efficiency in Natural Product Total Synthesis by : Pei-Qiang Huang

Download or read book Efficiency in Natural Product Total Synthesis written by Pei-Qiang Huang and published by John Wiley & Sons. This book was released on 2018-07-24 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. • Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science • Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis • Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section • Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals

Synthesis of Heterocycles via Multicomponent Reactions II

Author : Romano V. A. Orru
Publisher : Springer
ISBN 13 : 3642154557
Total Pages : 304 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Synthesis of Heterocycles via Multicomponent Reactions II by : Romano V. A. Orru

Download or read book Synthesis of Heterocycles via Multicomponent Reactions II written by Romano V. A. Orru and published by Springer. This book was released on 2010-07-26 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Géraldine Masson, Luc Neuville ∙ Carine Bughin ∙ Aude Fayol ∙ Jieping Zhu Multicomponent Syntheses of Macrocycles Thomas J.J. Müller Palladium-Copper Catalyzed Alkyne Activation as an Entry to Multicomponent Syntheses of Heterocycles Rachel Scheffelaar ∙ Eelco Ruijter ∙ Romano V.A. Orru Multicomponent Reaction Design Strategies: Towards Scaffold and Stereochemical Diversity Nicola Kielland ∙ Rodolfo Lavilla Recent Developments in Reissert-Type Multicomponent Reactions Jitender B. Bariwal ∙ Jalpa C. Trivedi ∙ Erik V. Van der Eycken Microwave Irradiation and Multicomponent Reactions Irini Akritopoulou-Zanze ∙ Stevan W. Djuric Applications of MCR-Derived Heterocycles in Drug Discovery

Isocyanide-based Multicomponent Reactions

Author : Jonathan G. Rudick
Publisher : Frontiers Media SA
ISBN 13 : 2889634841
Total Pages : 100 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Isocyanide-based Multicomponent Reactions by : Jonathan G. Rudick

Download or read book Isocyanide-based Multicomponent Reactions written by Jonathan G. Rudick and published by Frontiers Media SA. This book was released on 2020-02-20 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Green Organic Reactions

Author : Gopinathan Anilkumar
Publisher : Springer Nature
ISBN 13 : 9813368977
Total Pages : 349 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Green Organic Reactions by : Gopinathan Anilkumar

Download or read book Green Organic Reactions written by Gopinathan Anilkumar and published by Springer Nature. This book was released on 2021-03-27 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents important developments and applications of green chemistry, especially in the field of organic chemistry. The chapters give a brief account of green organic reactions in water, green organic reactions using microwave and in solvent-free conditions. In depth discussions on the green aspects of ionic liquids, flow reactions, and recoverable catalysts are provided in this book. An exclusive chapter devoted to green Lewis acid is also included. The potential of supercritical fluids as green solvents in various areas of organic reactions is explained as well. This book will be a valuable reference for beginners as well as advanced researchers interested in green organic chemistry.

Multicomponent Reactions

Author : Raquel P. Herrera
Publisher : John Wiley & Sons
ISBN 13 : 1118016009
Total Pages : 523 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Multicomponent Reactions by : Raquel P. Herrera

Download or read book Multicomponent Reactions written by Raquel P. Herrera and published by John Wiley & Sons. This book was released on 2015-04-27 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addressing a dynamic aspect of organic chemistry, this book describes synthetic strategies and applications for multicomponent reactions – including key routes for synthesizing complex molecules. • Illustrates the crucial role and the important utility of multicomponent reactions (MCRs) to organic syntheses • Compiles novel and efficient synthetic multicomponent procedures to give readers a complete picture of this class of organic reactions • Helps readers to design efficient and practical transformations using multicomponent reaction strategies • Describes reaction background, applications to synthesize complex molecules and drugs, and reaction mechanisms

Multicomponent Reactions

Author : Jieping Zhu
Publisher : John Wiley & Sons
ISBN 13 : 3527604243
Total Pages : 484 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Multicomponent Reactions by : Jieping Zhu

Download or read book Multicomponent Reactions written by Jieping Zhu and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the very first book on this hot topic, the expert editors andauthors present a comprehensive overview of these elegantreactions. From the contents: Organoboron compounds Free-radical mediated multicomponent coupling reactions Applications in drug discovery Metal catalyzed reactions Total synthesis of natural products Asymmetric isocyanide-based reactions The Biginelli reaction Asymmetric isocyanide-based reactions The Domino-Knoevenagel-Hetero-Diels-Alder Reaction and relatedtransformations Catalytic asymmetric reactions Algorithm based methods for discovering novel reactions Post-condensation modifications of the Passerini and Ugireactions An essential reference for organic and catalytic chemists, andthose working in organometallics both in academia and industry.

Dienamine Catalysis for Organic Synthesis

Author : Kengadarane Anebouselvy
Publisher : Royal Society of Chemistry
ISBN 13 : 1782620907
Total Pages : 220 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Dienamine Catalysis for Organic Synthesis by : Kengadarane Anebouselvy

Download or read book Dienamine Catalysis for Organic Synthesis written by Kengadarane Anebouselvy and published by Royal Society of Chemistry. This book was released on 2018-03-02 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade a new era in asymmetric catalysis has been realised by the discovery of L-proline induced chiral enamines from carbonyls. Inspired by this, researchers have developed many other primary catalytic species in situ, more recently secondary catalytic species such as aminals have been identified for use in asymmetric synthesis. High-yielding asymmetric synthesis of bioactive and natural products through mild catalysis is an efficient approach in reaction engineering. In the early days, synthetic chemists mainly focused on the synthesis of complex molecules, with less attention on the reaction efficiency and eco-friendly conditions. Recent investigations have been directed towards the development of atom economy, eco-friendly and enantioselective synthesis for more targeted and efficient synthesis. Building on the momentum of this rapidly expanding research area, Dienamine catalysis for organic synthesis will provide a comprehensive introduction, from the preformed species, in situ generation and onto their applications in the synthesis of bioactive molecules and natural products.

Superbases for Organic Synthesis

Author : Tsutomu Ishikawa
Publisher : John Wiley & Sons
ISBN 13 : 9780470740866
Total Pages : 336 pages
Book Rating : 4.7/5 (48 download)

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Book Synopsis Superbases for Organic Synthesis by : Tsutomu Ishikawa

Download or read book Superbases for Organic Synthesis written by Tsutomu Ishikawa and published by John Wiley & Sons. This book was released on 2009-01-26 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Guanidines, amidines and phosphazenes have been attracting attention in organic synthesis due to their potential functionality resulting from their extremely strong basicity. They are also promising catalysts because of their potential for easy molecular modification, possible recyclability, and reduced or zero toxicity. Importantly, these molecules can be derived as natural products – valuable as scientists move towards “sustainable chemistry”, where reagents and catalysts are derived from biomaterial sources. Superbases for Organic Synthesis is an essential guide to these important molecules for preparative organic synthesis. Topics covered include the following aspects: an introduction to organosuperbases physicochemical properties of organic superbases amidines and guanidines in organic synthesis phosphazene: preparation, reaction and catalytic role polymer-supported organosuperbases application of organosuperbases to total synthesis related organocatalysts: proton sponges and urea derivatives amidines and guanidines in natural products and medicines Superbases for Organic Synthesis is a comprehensive, authoritative and up-to-date guide to these important reagents for organic chemists, drug discovery researchers and those interested in the chemistry of natural products.

Multi-component Copper Catalyzed Methods to Access Highly-substituted Amine-bearing Carbon Centers from Simple Starting Materials

Download Multi-component Copper Catalyzed Methods to Access Highly-substituted Amine-bearing Carbon Centers from Simple Starting Materials PDF Online Free

Author : Conor John Pierce
Publisher :
ISBN 13 : 9781303507311
Total Pages : 289 pages
Book Rating : 4.5/5 (73 download)

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Book Synopsis Multi-component Copper Catalyzed Methods to Access Highly-substituted Amine-bearing Carbon Centers from Simple Starting Materials by : Conor John Pierce

Download or read book Multi-component Copper Catalyzed Methods to Access Highly-substituted Amine-bearing Carbon Centers from Simple Starting Materials written by Conor John Pierce and published by . This book was released on 2013 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: An alternate route to these densely-functionalized substrates was discovered to be a unique tandem hydroamination/alkynylation reaction. Markovnikov addition of an amine across a terminal alkyne yields enamine which, upon tautamerization to ketimine, is coupled with a second equivalent of the same alkyne to form propargylamine.

Multi-component Reactions in Molecular Diversity

Author : Jean-Philippe Goddard
Publisher : John Wiley & Sons
ISBN 13 : 1786305119
Total Pages : 198 pages
Book Rating : 4.7/5 (863 download)

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Book Synopsis Multi-component Reactions in Molecular Diversity by : Jean-Philippe Goddard

Download or read book Multi-component Reactions in Molecular Diversity written by Jean-Philippe Goddard and published by John Wiley & Sons. This book was released on 2020-04-28 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: While very useful for studying syntheses of molecular diversity, multi-component reactions also offer rapid access to a variety of complex molecules that are relevant for biological applications. Multi-component Reactions in Molecular Diversity analyzes these reactions, whether they are realized by organometallic, ionic or even radical processes. It highlights popular methods based on monotype reactions (cascade, tandem, domino) and their efficiency and academic industrial domain are illustrated. This book also investigates the most efficient ways to prepare complex molecules. Multi-component reactions are in tune with the concepts of atom and steps economy, which are of prior importance in all the reported processes ? from the laboratory to the pilot scale. The essential criteria for green chemistry are also examined in the book in detail.

Synthesis of Heterocycles Via Multicomponent Reactions II

Author :
Publisher :
ISBN 13 : 9783642154560
Total Pages : 292 pages
Book Rating : 4.1/5 (545 download)

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Book Synopsis Synthesis of Heterocycles Via Multicomponent Reactions II by :

Download or read book Synthesis of Heterocycles Via Multicomponent Reactions II written by and published by . This book was released on 2010 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Géraldine Masson, Luc Neuville ∙ Carine Bughin ∙ Aude Fayol ∙ Jieping Zhu Multicomponent Syntheses of Macrocycles Thomas J.J. Müller Palladium-Copper Catalyzed Alkyne Activation as an Entry to Multicomponent Syntheses of Heterocycles Rachel Scheffelaar ∙ Eelco Ruijter ∙ Romano V.A. Orru Multicomponent Reaction Design Strategies: Towards Scaffold and Stereochemical Diversity Nicola Kielland ∙ Rodolfo Lavilla Recent Developments in Reissert-Type Multicomponent Reactions Jitender B. Bariwal ∙ Jalpa C. Trivedi ∙ Erik V. Van der Eycken Microwave Irradiation and Multicomponent Reactions Irini Akritopoulou-Zanze ∙ Stevan W. Djuric Applications of MCR-Derived Heterocycles in Drug Discovery.

Multicomponent Reactions in Organic Synthesis

Author : Jieping Zhu
Publisher : John Wiley & Sons
ISBN 13 : 3527332375
Total Pages : 512 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Multicomponent Reactions in Organic Synthesis by : Jieping Zhu

Download or read book Multicomponent Reactions in Organic Synthesis written by Jieping Zhu and published by John Wiley & Sons. This book was released on 2015-02-09 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive and up-to-date, this book focuses on the latest advances in the field, such as newly developed techniques, more environmentally benign processes, broadened scopes, and completely novel MCRs. In addition to carbene-promoted MCRs and frequently applied metal-catalyzed MCRs, it also covers recently developed catalytic enantioselective variants as well as MCR in drug discovery and for the synthesis of heterocyclic molecules and macrocycles. Edited by the leading experts and with a list of authors reading like a "who's who" in multicomponent reaction chemistry, this is definitely a must-have for every synthetic organic chemist as well as medicinal chemists working in academia and pharmaceutical companies.

Multicomponent Reactions towards Heterocycles

Author : Erik Van der Eycken
Publisher : John Wiley & Sons
ISBN 13 : 3527349081
Total Pages : 626 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Multicomponent Reactions towards Heterocycles by : Erik Van der Eycken

Download or read book Multicomponent Reactions towards Heterocycles written by Erik Van der Eycken and published by John Wiley & Sons. This book was released on 2022-03-21 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a wide-ranging overview of essential topics and recent advances in MCR chemistry Heterocycles are a central component in natural product chemistry, pharmaceuticals, agrochemicals, and material science. New synthetic methodologies integrating the sequencing of multicomponent reactions (MCRs) are today being used for the rapid synthesis of diversified heterocycles in just one step. Multicomponent Reactions towards Heterocycles presents an up-to-date summary MCR chemistry with a focus on the conjugation between modern synthetic methodologies and MCRs. Featuring contributions by leaders in the field, this comprehensive resource highlights applications of MCRs in natural products and intermediate synthesis, discusses current trends and future prospects in MCR chemistry, outlines novel multicomponent procedures, and more. The authors provide the practical information required for designing new reaction strategies and mechanisms, covering topics including MCR-based green synthetic methods, cyclization and cycloaddition reactions, heterocycle multicomponent syntheses in a continuous flow, catalytic alkynoyl generation, MCR synthesis of saturated heterocycles, and C–H functionalization and multicomponent reactions. Provides a thorough overview of heterocycles as input in multicomponent reactions Discusses recent advances in the field of MCR chemistry and progress in the synthesis and functionalization of heterocycles Demonstrates the use of MCRs to simplify synthetic design and achieve complexity and diversity in novel bioactive molecules Highlights examples of multicomponent polymerizations, target-oriented synthesis, and applications of MCR in medicinal chemistry Explains the methodology of using on-resin MCRs to produce heterocycle compounds Illustrating the key role of MCRs towards heterocycles in natural product synthesis, drug discovery, organic synthesis, and other applications, Multicomponent Reactions towards Heterocycles is required reading for synthetic chemists in academia and industry alike.

Multi-Component and Sequential Reactions in Polymer Synthesis

Author : Patrick Theato
Publisher : Springer
ISBN 13 : 3319207202
Total Pages : 209 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Multi-Component and Sequential Reactions in Polymer Synthesis by : Patrick Theato

Download or read book Multi-Component and Sequential Reactions in Polymer Synthesis written by Patrick Theato and published by Springer. This book was released on 2015-07-06 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Advances in Polymer Science presents critical reviews of the present and future trends in polymer and biopolymer science. It covers all areas of research in polymer and biopolymer science including chemistry, physical chemistry, physics, material science. The thematic volumes are addressed to scientists, whether at universities or in industry, who wish to keep abreast of the important advances in the covered topics. Advances in Polymer Science enjoys a longstanding tradition and good reputation in its community. Each volume is dedicated to a current topic and each review critically surveys one aspect of that topic, to place it within the context of the volume. The volumes typically summarize the significant developments of the last 5 to 10 years and discuss them critically, presenting selected examples, explaining and illustrating the important principles and bringing together many important references of primary literature. On that basis, future research directions in the area can be discussed. Advances in Polymer Science volumes thus are important references for every polymer scientist, as well as for other scientists interested in polymer science as an introduction to a neighboring field or as a compilation of detailed information for the specialist. Review articles for the individual volumes are invited by the volume editors. Single contributions can be specially commissioned. Readership: Polymer scientists or scientists in related fields interested in polymer and biopolymer science, at universities or in industry, graduate students.