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Comparison Of Resampling Methods For Improving Confidence Intervals In Group Sequential Trials On Rare Event Target Populations
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Book Synopsis Comparison of Resampling Methods for Improving Confidence Intervals in Group Sequential Trials on Rare Event Target Populations by : S. Thomas Cleveland
Download or read book Comparison of Resampling Methods for Improving Confidence Intervals in Group Sequential Trials on Rare Event Target Populations written by S. Thomas Cleveland and published by . This book was released on 2002 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Analysis of Clinical Trials Using SAS by : Alex Dmitrienko
Download or read book Analysis of Clinical Trials Using SAS written by Alex Dmitrienko and published by SAS Institute. This book was released on 2017-07-17 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analysis of Clinical Trials Using SAS®: A Practical Guide, Second Edition bridges the gap between modern statistical methodology and real-world clinical trial applications. Tutorial material and step-by-step instructions illustrated with examples from actual trials serve to define relevant statistical approaches, describe their clinical trial applications, and implement the approaches rapidly and efficiently using the power of SAS. Topics reflect the International Conference on Harmonization (ICH) guidelines for the pharmaceutical industry and address important statistical problems encountered in clinical trials. Commonly used methods are covered, including dose-escalation and dose-finding methods that are applied in Phase I and Phase II clinical trials, as well as important trial designs and analysis strategies that are employed in Phase II and Phase III clinical trials, such as multiplicity adjustment, data monitoring, and methods for handling incomplete data. This book also features recommendations from clinical trial experts and a discussion of relevant regulatory guidelines. This new edition includes more examples and case studies, new approaches for addressing statistical problems, and the following new technological updates: SAS procedures used in group sequential trials (PROC SEQDESIGN and PROC SEQTEST) SAS procedures used in repeated measures analysis (PROC GLIMMIX and PROC GEE) macros for implementing a broad range of randomization-based methods in clinical trials, performing complex multiplicity adjustments, and investigating the design and analysis of early phase trials (Phase I dose-escalation trials and Phase II dose-finding trials) Clinical statisticians, research scientists, and graduate students in biostatistics will greatly benefit from the decades of clinical research experience and the ready-to-use SAS macros compiled in this book.
Book Synopsis Statistics with Confidence by : Douglas Altman
Download or read book Statistics with Confidence written by Douglas Altman and published by John Wiley & Sons. This book was released on 2013-06-03 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly popular introduction to confidence intervals has been thoroughly updated and expanded. It includes methods for using confidence intervals, with illustrative worked examples and extensive guidelines and checklists to help the novice.
Book Synopsis Introduction to Statistics Through Resampling Methods and Microsoft Office Excel by : Phillip I. Good
Download or read book Introduction to Statistics Through Resampling Methods and Microsoft Office Excel written by Phillip I. Good and published by John Wiley & Sons. This book was released on 2005-07-22 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn statistical methods quickly and easily with the discovery method With its emphasis on the discovery method, this publication encourages readers to discover solutions on their own rather than simply copy answers or apply a formula by rote. Readers quickly master and learn to apply statistical methods, such as bootstrap, decision trees, t-test, and permutations to better characterize, report, test, and classify their research findings. In addition to traditional methods, specialized methods are covered, allowing readers to select and apply the most effective method for their research, including: * Tests and estimation procedures for one, two, and multiple samples * Model building * Multivariate analysis * Complex experimental design Throughout the text, Microsoft Office Excel(r) is used to illustrate new concepts and assist readers in completing exercises. An Excel Primer is included as an Appendix for readers who need to learn or brush up on their Excel skills. Written in an informal, highly accessible style, this text is an excellent guide to descriptive statistics, estimation, testing hypotheses, and model building. All the pedagogical tools needed to facilitate quick learning are provided: * More than 100 exercises scattered throughout the text stimulate readers' thinking and actively engage them in applying their newfound skills * Companion FTP site provides access to all data sets discussed in the text * An Instructor's Manual is available upon request from the publisher * Dozens of thought-provoking questions in the final chapter assist readers in applying statistics to solve real-life problems * Helpful appendices include an index to Excel and Excel add-in functions This text serves as an excellent introduction to statistics for students in all disciplines. The accessible style and focus on real-life problem solving are perfectly suited to both students and practitioners.
Book Synopsis Statistical Methods in Water Resources by : D.R. Helsel
Download or read book Statistical Methods in Water Resources written by D.R. Helsel and published by Elsevier. This book was released on 1993-03-03 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data on water quality and other environmental issues are being collected at an ever-increasing rate. In the past, however, the techniques used by scientists to interpret this data have not progressed as quickly. This is a book of modern statistical methods for analysis of practical problems in water quality and water resources.The last fifteen years have seen major advances in the fields of exploratory data analysis (EDA) and robust statistical methods. The 'real-life' characteristics of environmental data tend to drive analysis towards the use of these methods. These advances are presented in a practical and relevant format. Alternate methods are compared, highlighting the strengths and weaknesses of each as applied to environmental data. Techniques for trend analysis and dealing with water below the detection limit are topics covered, which are of great interest to consultants in water-quality and hydrology, scientists in state, provincial and federal water resources, and geological survey agencies.The practising water resources scientist will find the worked examples using actual field data from case studies of environmental problems, of real value. Exercises at the end of each chapter enable the mechanics of the methodological process to be fully understood, with data sets included on diskette for easy use. The result is a book that is both up-to-date and immediately relevant to ongoing work in the environmental and water sciences.
Book Synopsis Meta-Analysis with R by : Guido Schwarzer
Download or read book Meta-Analysis with R written by Guido Schwarzer and published by Springer. This book was released on 2015-10-08 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive introduction to performing meta-analysis using the statistical software R. It is intended for quantitative researchers and students in the medical and social sciences who wish to learn how to perform meta-analysis with R. As such, the book introduces the key concepts and models used in meta-analysis. It also includes chapters on the following advanced topics: publication bias and small study effects; missing data; multivariate meta-analysis, network meta-analysis; and meta-analysis of diagnostic studies.
Download or read book Sampling written by Sharon L. Lohr and published by CRC Press. This book was released on 2019-04-08 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edition is a reprint of the second edition published by Cengage Learning, Inc. Reprinted with permission. What is the unemployment rate? How many adults have high blood pressure? What is the total area of land planted with soybeans? Sampling: Design and Analysis tells you how to design and analyze surveys to answer these and other questions. This authoritative text, used as a standard reference by numerous survey organizations, teaches sampling using real data sets from social sciences, public opinion research, medicine, public health, economics, agriculture, ecology, and other fields. The book is accessible to students from a wide range of statistical backgrounds. By appropriate choice of sections, it can be used for a graduate class for statistics students or for a class with students from business, sociology, psychology, or biology. Readers should be familiar with concepts from an introductory statistics class including linear regression; optional sections contain the statistical theory, for readers who have studied mathematical statistics. Distinctive features include: More than 450 exercises. In each chapter, Introductory Exercises develop skills, Working with Data Exercises give practice with data from surveys, Working with Theory Exercises allow students to investigate statistical properties of estimators, and Projects and Activities Exercises integrate concepts. A solutions manual is available. An emphasis on survey design. Coverage of simple random, stratified, and cluster sampling; ratio estimation; constructing survey weights; jackknife and bootstrap; nonresponse; chi-squared tests and regression analysis. Graphing data from surveys. Computer code using SAS® software. Online supplements containing data sets, computer programs, and additional material. Sharon Lohr, the author of Measuring Crime: Behind the Statistics, has published widely about survey sampling and statistical methods for education, public policy, law, and crime. She has been recognized as Fellow of the American Statistical Association, elected member of the International Statistical Institute, and recipient of the Gertrude M. Cox Statistics Award and the Deming Lecturer Award. Formerly Dean’s Distinguished Professor of Statistics at Arizona State University and a Vice President at Westat, she is now a freelance statistical consultant and writer. Visit her website at www.sharonlohr.com.
Book Synopsis Targeted Learning by : Mark J. van der Laan
Download or read book Targeted Learning written by Mark J. van der Laan and published by Springer Science & Business Media. This book was released on 2011-06-17 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: The statistics profession is at a unique point in history. The need for valid statistical tools is greater than ever; data sets are massive, often measuring hundreds of thousands of measurements for a single subject. The field is ready to move towards clear objective benchmarks under which tools can be evaluated. Targeted learning allows (1) the full generalization and utilization of cross-validation as an estimator selection tool so that the subjective choices made by humans are now made by the machine, and (2) targeting the fitting of the probability distribution of the data toward the target parameter representing the scientific question of interest. This book is aimed at both statisticians and applied researchers interested in causal inference and general effect estimation for observational and experimental data. Part I is an accessible introduction to super learning and the targeted maximum likelihood estimator, including related concepts necessary to understand and apply these methods. Parts II-IX handle complex data structures and topics applied researchers will immediately recognize from their own research, including time-to-event outcomes, direct and indirect effects, positivity violations, case-control studies, censored data, longitudinal data, and genomic studies.
Book Synopsis Multivariate Permutation Tests by : Fortunato Pesarin
Download or read book Multivariate Permutation Tests written by Fortunato Pesarin and published by Wiley. This book was released on 2001-06-08 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complex multivariate problems are frequently encountered in many scientific disciplines and it can be very difficult to obtain meaningful results. Permutation and nonparametric combination methods provide flexible solutions to complex problems by reducing the problem down to a set of simpler sub-problems. The author presents a novel but well tested approach using real examples taken from biomedical research. Statistical analyses are performed in a nonparametric setting, so that no assumptions need be made about the underlying distribution and the dependence relations between variables. * Provides a clear exposition of the use of multivariate permutation testing, with emphasis on the use of nonparametric combination methodology. * Growing area of research with many practical applications, notably in biostatistics. * Numerous case studies and examples help to illustrate the theory. * Provides solutions to multi-aspect problems, to problems with missing data, analysis of factorial designs and repeated measures. * Explains the analysis of categorical, ordered categorical, binary, continuous, and mixed variables in both an experimental and an observational context. * NPC-Test(c) software (demo copy), SAS macros, S-Plus code and datasets are available on the Web at http://www.stat.unipd.it/~pesarin/ For researchers and practitioners in a number of scientific disciplines, particularly biostatistics, the vast collection of techniques, examples and case studies will be an invaluable resource. Graduate students of applied statistics and nonparametric methods will find the book provides an accessible introduction to multivariate permutation testing.
Book Synopsis Recent Developments in Multiple Comparison Procedures by : Yoav Benjamini
Download or read book Recent Developments in Multiple Comparison Procedures written by Yoav Benjamini and published by IMS. This book was released on 2004 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Understanding The New Statistics by : Geoff Cumming
Download or read book Understanding The New Statistics written by Geoff Cumming and published by Routledge. This book was released on 2013-06-19 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to introduce the new statistics - effect sizes, confidence intervals, and meta-analysis - in an accessible way. It is chock full of practical examples and tips on how to analyze and report research results using these techniques. The book is invaluable to readers interested in meeting the new APA Publication Manual guidelines by adopting the new statistics - which are more informative than null hypothesis significance testing, and becoming widely used in many disciplines. Accompanying the book is the Exploratory Software for Confidence Intervals (ESCI) package, free software that runs under Excel and is accessible at www.thenewstatistics.com. The book’s exercises use ESCI's simulations, which are highly visual and interactive, to engage users and encourage exploration. Working with the simulations strengthens understanding of key statistical ideas. There are also many examples, and detailed guidance to show readers how to analyze their own data using the new statistics, and practical strategies for interpreting the results. A particular strength of the book is its explanation of meta-analysis, using simple diagrams and examples. Understanding meta-analysis is increasingly important, even at undergraduate levels, because medicine, psychology and many other disciplines now use meta-analysis to assemble the evidence needed for evidence-based practice. The book’s pedagogical program, built on cognitive science principles, reinforces learning: Boxes provide "evidence-based" advice on the most effective statistical techniques. Numerous examples reinforce learning, and show that many disciplines are using the new statistics. Graphs are tied in with ESCI to make important concepts vividly clear and memorable. Opening overviews and end of chapter take-home messages summarize key points. Exercises encourage exploration, deep understanding, and practical applications. This highly accessible book is intended as the core text for any course that emphasizes the new statistics, or as a supplementary text for graduate and/or advanced undergraduate courses in statistics and research methods in departments of psychology, education, human development , nursing, and natural, social, and life sciences. Researchers and practitioners interested in understanding the new statistics, and future published research, will also appreciate this book. A basic familiarity with introductory statistics is assumed.
Book Synopsis Resampling-Based Multiple Testing by : Peter H. Westfall
Download or read book Resampling-Based Multiple Testing written by Peter H. Westfall and published by John Wiley & Sons. This book was released on 1993-01-12 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combines recent developments in resampling technology (including the bootstrap) with new methods for multiple testing that are easy to use, convenient to report and widely applicable. Software from SAS Institute is available to execute many of the methods and programming is straightforward for other applications. Explains how to summarize results using adjusted p-values which do not necessitate cumbersome table look-ups. Demonstrates how to incorporate logical constraints among hypotheses, further improving power.
Book Synopsis Measuring and Monitoring Plant Populations by : Caryl Elzinga
Download or read book Measuring and Monitoring Plant Populations written by Caryl Elzinga and published by Createspace Independent Publishing Platform. This book was released on 2015-01-02 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: This technical reference applies to monitoring situations involving a single plant species, such as an indicator species, key species, or weed. It was originally developed for monitoring special status plants, which have some recognized status at the Federal, State, or agency level because of their rarity or vulnerability. Most examples and discussions in this technical reference focus on these special status species, but the methods described are also applicable to any single-species monitoring and even some community monitoring situations.We thus hope wildlife biologists, range conservationists, botanists, and ecologists will all find this technical reference helpful.
Book Synopsis Statistics in Medicine by : Robert H. Riffenburgh
Download or read book Statistics in Medicine written by Robert H. Riffenburgh and published by Academic Press. This book was released on 2006 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicine deals with treatments that work often but not always, so treatment success must be based on probability. Statistical methods lift medical research from the anecdotal to measured levels of probability. This book presents the common statistical methods used in 90% of medical research, along with the underlying basics, in two parts: a textbook section for use by students in health care training programs, e.g., medical schools or residency training, and a reference section for use by practicing clinicians in reading medical literature and performing their own research. The book does not require a significant level of mathematical knowledge and couches the methods in multiple examples drawn from clinical medicine, giving it applicable context. Easy-to-follow format incorporates medical examples, step-by-step methods, and check yourself exercises Two-part design features course material and a professional reference section Chapter summaries provide a review of formulas, method algorithms, and check lists Companion site links to statistical databases that can be downloaded and used to perform the exercises from the book and practice statistical methods New in this Edition: New chapters on: multifactor tests on means of continuous data, equivalence testing, and advanced methods New topics include: trial randomization, treatment ethics in medical research, imputation of missing data, and making evidence-based medical decisions Updated database coverage and additional exercises Expanded coverage of numbers needed to treat and to benefit, and regression analysis including stepwise regression and Cox regression Thorough discussion on required sample size
Book Synopsis Introduction to Probability and Statistics Using R by : G. Jay Kerns
Download or read book Introduction to Probability and Statistics Using R written by G. Jay Kerns and published by Lulu.com. This book was released on 2010-01-10 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a textbook for an undergraduate course in probability and statistics. The approximate prerequisites are two or three semesters of calculus and some linear algebra. Students attending the class include mathematics, engineering, and computer science majors.
Book Synopsis Experimental and Quasi-experimental Designs for Generalized Causal Inference by : William R. Shadish
Download or read book Experimental and Quasi-experimental Designs for Generalized Causal Inference written by William R. Shadish and published by Cengage Learning. This book was released on 2002 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sections include: experiments and generalised causal inference; statistical conclusion validity and internal validity; construct validity and external validity; quasi-experimental designs that either lack a control group or lack pretest observations on the outcome; quasi-experimental designs that use both control groups and pretests; quasi-experiments: interrupted time-series designs; regresssion discontinuity designs; randomised experiments: rationale, designs, and conditions conducive to doing them; practical problems 1: ethics, participation recruitment and random assignment; practical problems 2: treatment implementation and attrition; generalised causal inference: a grounded theory; generalised causal inference: methods for single studies; generalised causal inference: methods for multiple studies; a critical assessment of our assumptions.
Book Synopsis Users' Guides to the Medical Literature by : Gordon Guyatt
Download or read book Users' Guides to the Medical Literature written by Gordon Guyatt and published by McGraw Hill Professional. This book was released on 2008-03-01 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: The “essential” companion to the landmark Users' Guides to the Medical Literature - completely revised and updated! 5 STAR DOODY'S REVIEW! "This second edition is even better than the original. Information is easier to find and the additional resources that will be available at www.JAMAevidence.com will provide readers with a one-stop source for evidence-based medicine."--Doody's Review Service Evidence-based medicine involves the careful interpretation of medical studies and its clinical application. And no resource helps you do it better-and faster-than Users' Guides to the Medical Literature: Essentials of Evidence-Based Clinical Practice. This streamlined reference distills the most clinically-relevant coverage from the parent Users' Guide Manual into one highly-focused, portable resource. Praised for its clear explanations of detailed statistical and mathematical principles, The Essentials concisely covers all the basic concepts of evidence-based medicine--everything you need to deliver optimal patient care. It's a perfect at-a-glance source for busy clinicians and students, helping you distinguish between solid medical evidence and poor medical evidence, tailor evidence-based medicine for each patient, and much more. Now in its second edition, this carry-along quick reference is more clinically relevant--and more essential--than ever! FEATURES Completely revised and updated with all new coverage of the basic issues in evidence-based medicine in patient care Abundant real-world examples drawn from the medical literature are woven throughout, and include important related principles and pitfalls in using clinical research in patient care decisions Edited by over 60 internationally recognized editors and contributors from around the globe Also look for JAMAevidence.com, a new interactive database for the best practice of evidence based medicine.
