Comparing Salivary And Plaque Microbiomes In Fixed Vs Removable Orthodontic Treatment

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Comparing Salivary and Plaque Microbiomes in Fixed Vs Removable Orthodontic Treatment

Author : Arvin Pal
Publisher :
ISBN 13 :
Total Pages : 55 pages
Book Rating : 4.:/5 (13 download)

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Book Synopsis Comparing Salivary and Plaque Microbiomes in Fixed Vs Removable Orthodontic Treatment by : Arvin Pal

Download or read book Comparing Salivary and Plaque Microbiomes in Fixed Vs Removable Orthodontic Treatment written by Arvin Pal and published by . This book was released on 2022 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt: BackgroundToday, we know that the oral microbiome is the second most abundant microbiome in the human body, after the gastrointestinal tract, and comprises a delicate ecosystem which consists of hundreds of different predominantly commensal but also pathogenic bacteria 2. The average adult can harbor as many as 100 billion bacteria in their mouth, and the accessibility of the oral cavity makes this massive microbiome uniquely convenient for scientific investigation. The most common pathologies associated with oral microorganisms are dental caries and periodontal disease. Numerous studies have shown common microbial shifts associated with oral disease, but it is not clearly exactly which bacteria are involved in these shifts, especially in patients with orthodontic appliances. ObjectiveIn this study, we analyze the salivary microbiome of patients undergoing orthodontic treatment using either traditional metal braces or removable clear aligners. The salivary microbiome of these patients is compared to the respective microbiomes found in the tooth-associated plaque above the gingival margin, as well as the plaque found on the clear aligner trays themselves, throughout the first 12 months of orthodontic treatment. Clinical data, such as plaque levels and gingival health, are also compared with changes in salivary microbial composition throughout treatment, in order to identify a potential relationship between microbial composition and oral health during orthodontic treatment. MethodsClinical data, saliva, and plaque samples were collected at the following orthodontic treatment timepoints for both clear aligner and fixed appliance patients: 0 months, 1 month, 3 months, 6 months, and 12 months. Plaque levels were quantified using Turesky et al. Modified Quigley-Hein Plaque Index (PI), and 36; 37 gingival health was measured using the L e and Silness Gingival Index (GI) 38. Next generation sequencing of the V1 to V3 region of the 16S rRNA gene from DNA extracted from the saliva and plaque samples and microbial community analysis was performed. Standard microbial community data analysis was performed with bioinformatic protocols. ResultsThe average age of the fixed appliance group (23.0 13.6 years) was lower than the average age of the clear aligner group (30.9 12.3 years), but the difference was not significant (p = 0.201). Plaque and gingival index scores are significantly (p

Initial Changes In The Oral Microbiome In Orthodontic Patients During Treatment

Author : Andrew Hopkins
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Initial Changes In The Oral Microbiome In Orthodontic Patients During Treatment by : Andrew Hopkins

Download or read book Initial Changes In The Oral Microbiome In Orthodontic Patients During Treatment written by Andrew Hopkins and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Background: The oral microbiome is host to a diverse set of microbes and is extremely dynamic depending on the environment that it is placed in. Microbial profile changes are associated with a patient's ability to practice proper oral hygiene, the diet they maintain, adequate salivary flow and composition, and a myriad of other contributing factors. Orthodontic appliances pose as an obstacle as they act as plaque retentive surfaces on the teeth and hinder the patient's ability to perform oral hygiene successfully. The inability to remove plaque allows it to develop into a mature biofilm, capable of causing dental diseases such as caries and periodontal disease.Objective: Our study aims to investigate how patients microbial profiles and gingival/plaque indices change over time comparing patients undergoing orthodontic therapy through fixed appliances with those receiving clear aligner therapy with a focus on early time points. Methods: The study was performed on a total of nine patients, five of which received fixed appliances and four received clear aligner therapy. Both supragingival and subgingival bacterial samples were collected at six different timepoints: T0 (baseline directly before orthodontic treatment commences), T1 (one-week after orthodontic treatment commences), T2 (two- weeks), T3 (three-weeks), T4 (four-week) and T5 (three-months). Additionally, at each visit the gingival and plaque indices were recorded. The indices were compared within each group at successive time points as well as between both treatment groups. The composition of the plaque samples was elucidated by extracting the DNA and performing next generation sequencing of the 16S rRNA. Changes in plaque profiles, diversity, and overall composition were compared between timepoints and between both treatment groups. Results: The results of the study showed that there was a general trend for higher gingival indices in patients undergoing FA when compared to CA therapy, which was statistically significant at T5 (p

The Oral Microbiome and Clinical Changes in Patients with Fixed and Clear Aligner Orthodontic Appliance After Debonding

Author : Oman Konia
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (138 download)

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Book Synopsis The Oral Microbiome and Clinical Changes in Patients with Fixed and Clear Aligner Orthodontic Appliance After Debonding by : Oman Konia

Download or read book The Oral Microbiome and Clinical Changes in Patients with Fixed and Clear Aligner Orthodontic Appliance After Debonding written by Oman Konia and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Background:The most popular method for addressing malocclusion is by using fixed or removable orthodontic devices. However, these appliances can inadvertently accumulate plaque shortly after their application, which can lead to an imbalance in the bacterial population. This bacterial dysbiosis could increase the risk of several health issues, including dental caries, white spot lesions, periodontal diseases, and even metabolic diseases. This research investigates the changes in the gingival and plaque indices and the bacterial composition following the removal of orthodontic devices. Moreover, this work explores the ambiguity surrounding whether microbiological and clinical changes experienced by patients during orthodontic treatment are reversible post-therapy and compares the changes for fixed and clear aligner Orthodontic appliances Objective: To analyze the initial changes in clinical parameters and plaque levels of periodontal pathogens after orthodontic treatment with fixed or removable appliances. Materials and Methods: The subjects consisted of 14 patients completing orthodontic treatment ready for debonding. The Plaque Index and Gingival Index were measured as periodontal parameters. Both the plaque and gingival indexes were obtained from the central incisors, lateral incisors, canines, and first molars of both arches. Plaque and periodontal parameters were obtained at the following three-time points: at debonding (T0), 1 month (T1), and 3 months (T2) after debonding. Deep 16S rRNA sequencing was performed for the supra gingival plaques to analyze the correlation with the clinical indexes and to see the microbial community composition after debonding at 3-time points (T0, T1, and T2). Results: The Fixed appliance (FA) group had a statistically significant greater overall GI score than the Clear aligner (CA) group at time T0 (p

Characterization of the Oral Microbiome in Orthodontic Patients

Author : Edward Viloria
Publisher :
ISBN 13 :
Total Pages : 39 pages
Book Rating : 4.:/5 (113 download)

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Book Synopsis Characterization of the Oral Microbiome in Orthodontic Patients by : Edward Viloria

Download or read book Characterization of the Oral Microbiome in Orthodontic Patients written by Edward Viloria and published by . This book was released on 2019 with total page 39 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are approximately 700 bacterial species present in the oral cavity that exist in a complex, delicately balanced ecosystem. Orthodontic treatment with fixed appliances has been shown to disrupt this balance leading to an increased risk of white spot lesions, caries and periodontal disease. With the advent of clear aligners, orthodontic patients are now able to remove their appliances and perform oral hygiene more efficiently. Previous studies have examined the effects of fixed and removable orthodontic appliances on periodontal health with varying results. We examined patients at the UCLA Orthodontics Clinic with fixed appliances (n=12) and clear aligners (n=12) through the first six months of treatment. Periodontal status was evaluated using the Turesky et al. Modified Quigley-Hein Plaque Index (PI) and the L e and Silness Gingival Index (GI). Plaque was collected from anterior teeth, posterior teeth and from the inner surface of the clear aligner trays. DNA from the plaque samples was extracted and subjected to next generation sequencing of the 16S rRNA gene. There was a significant increase in PI and GI in the fixed appliance group over the first six months of treatment. In the clear aligner group, there was no significant increase in PI, but there was a significant, yet transient increase in GI that eventually returned to baseline levels. Distinct, patient-specific shifts in the microbial communities were observed in both groups upon starting treatment. The microbial community inside the clear aligners is unique and less diverse than those found on teeth, but the overall composition of tooth-associated biofilm was similar between both groups. Patients treated with fixed appliances experienced significantly more plaque accumulation on the surfaces of the teeth compared to patients treated with clear aligners. This increase in plaque accumulation in the fixed appliance group was associated with a significant increase in gingival inflammation, which was localized to the posterior teeth. The inner surfaces of the clear aligner trays harbor a unique microbial community that is less diverse than those found in tooth-associated biofilms.

Promoting Dental Health in Orthodontic Patients

Author : Fredrik Lundström
Publisher :
ISBN 13 :
Total Pages : 134 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Promoting Dental Health in Orthodontic Patients by : Fredrik Lundström

Download or read book Promoting Dental Health in Orthodontic Patients written by Fredrik Lundström and published by . This book was released on 1985 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Effects of White Spot Lesion Therapy on Different Salivary Parameters After Removal of Fixed Orthodontic Appliances

Author : Shahin Setoudeh Maram
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (138 download)

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Book Synopsis The Effects of White Spot Lesion Therapy on Different Salivary Parameters After Removal of Fixed Orthodontic Appliances by : Shahin Setoudeh Maram

Download or read book The Effects of White Spot Lesion Therapy on Different Salivary Parameters After Removal of Fixed Orthodontic Appliances written by Shahin Setoudeh Maram and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although orthodontic treatment does not directly damage the teeth, it causes a change in the oral environment leading to an increased risk of periodontal disease and white spot lesions (WSLs), which are visible areas of demineralized enamel. This study aims to investigate the efficacy of different commercially available fluoride varnishes to treat WSLs after the completion of orthodontic treatment and evaluate their effect on the salivary parameters and the oral microbiome. The study followed a split-mouth design, with each of the subjects receiving different treatment on the left and right sides of their mouth. Subjects were assigned to one of three groups, with each group receiving two of the following three treatment options: placebo varnish (petroleum jelly), 5% sodium fluoride varnish (Henry Schein Acclean), and a light-cured fluoride varnish (3M XT Extended Contact Varnish). There were a total of 4 visits for this study: T0 (within 30 days of removing braces), T1 (day 30), T2 (day 90), and T3 (day 180). At each visit, subjects completed an Oral Health Questionnaire and the severity of the WSLs was assessed using DIAGNOdent laser fluorescence pen. The scores were used to assess the efficacy of the different interventions at re-mineralizing WSLs. To test the resting flow rate of saliva and salivary consistency, lower lip labial secretion and the resting salivary consistency in the oral cavity were visually assessed, respectively. Collected saliva was kept for measuring flow rate, pH, and buffering capacity. Although the study is still ongoing and therefore had a small sample size of 17 subjects enrolled at the time of data analysis, some notable trends were observed. DIAGNOdent measurements showed an interesting trend with a decrease of 20% in scores for WSLs treated with the placebo varnish and 5% NaF groups over the observation period. In contrast, the LCFV group showed a small albeit not significant increase in DIAGNOdent scores during the first 6 months after orthodontic treatment. The differences in pH between the treatments were relatively small and not clinically significant. When examining the colony-forming units (CFUs), an interesting pattern emerged in terms of the proportions of S. mutans and C. albicans relative to the total microbial load. The non-significant 9.75% increase in total microbial load, was accompanied by an 81.66% decrease in C. albicans load, and an 81.35% decrease in S. mutans load. This resulted in an overall decreasing trend in the proportions of S. mutans and C. albicans relative to the total bacterial load. However, to obtain more reliable and conclusive results it is necessary to increase the sample size.

ORAL MICROFLORA CHANGES IN ORTHODONTIC TREATMENT

Author : Dr. Chandresh Shukla
Publisher : Book Rivers
ISBN 13 : 9355151144
Total Pages : 62 pages
Book Rating : 4.3/5 (551 download)

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Book Synopsis ORAL MICROFLORA CHANGES IN ORTHODONTIC TREATMENT by : Dr. Chandresh Shukla

Download or read book ORAL MICROFLORA CHANGES IN ORTHODONTIC TREATMENT written by Dr. Chandresh Shukla and published by Book Rivers. This book was released on 2022-05-24 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cumulated Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 1912 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1997 with total page 1912 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Orthodontic Therapeutic Biomarkers in Saliva and Gingival Crevicular Fluid

Author : Sagar S. Bhat
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis Orthodontic Therapeutic Biomarkers in Saliva and Gingival Crevicular Fluid by : Sagar S. Bhat

Download or read book Orthodontic Therapeutic Biomarkers in Saliva and Gingival Crevicular Fluid written by Sagar S. Bhat and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several biologically active substances representing the bone deposition and resorption processes are released following damage to periodontal tissue during orthodontic movement. Biomarkers are by definition objective, quantifiable characteristics of biological processes. The analysis of saliva/salivary fluid and Gingival crevicular fluid (GCF) may be an accepted way to examine the ongoing biochemical processes associated with bone turnover during orthodontic tooth movement and fixed orthodontic treatment pain. Assessing the presence of these salivary physiological biomarkers would benefit the clinician in appropriate pain diagnosis and management objectively of various problems encountered during the orthodontic procedures and for better outcome of biomechanical therapy. Due to lack of standardized collection procedure, even though well accepted by patients, saliva is often neglected as a body fluid of diagnostic and prognostic value. A literature search was carried out in major databases such as PubMed, Medline, Cochrane library, Web of Science, Google Scholar, Scopus and EMBASE for relevant studies. Publication in English between 2000 to 2021 which estimated Saliva markers as indicators of orthodontic tooth movement was included. The list of biomarkers available to date was compiled and is presented in table format. Each biomarker is discussed separately based on the available and collected evidences. Several sensitive salivary and GCF biomarkers are available to detect the biomechanical changes occurring during orthodontic tooth movement and pain occurring during fixed orthodontic therapy. Further focussed research might help to analyze the sensitivity and reliability of these biomarkers or cytokines, which in turn can lead to the development of chairside tests to assess the pain experienced by patients during orthodontic therapy and finally the outcome of the fixed orthodontic therapy.

Biological Mechanisms of Tooth Movement

Author : Vinod Krishnan
Publisher : John Wiley & Sons
ISBN 13 : 1405176903
Total Pages : 310 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Biological Mechanisms of Tooth Movement by : Vinod Krishnan

Download or read book Biological Mechanisms of Tooth Movement written by Vinod Krishnan and published by John Wiley & Sons. This book was released on 2009-03-09 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: The adaptation and development of biological concepts in orthodontics / Ze'evDavidovitch and Neal C. Murphy -- Biology of orthodontic tooth movement : an overview / Vinod Krishnan, Young Guk Park and Ze'ev Davidovitch -- The effects of mechanical loading on hard and soft tissues and cells / Itzhak Binderman . [und weitere] -- Genetic influences on orthodontic tooth movement / Maggie Zeichner-David -- The role of inflammation in defining the type and pattern of tissue response in orthodontic tooth movement / Masaru Yamaguchi -- Biological aspects of bone growth and metabolism in orthodontics / Song Chen, James K. Hartsfield Jr. and W. Eugene Roberts -- Markers of paradental tissue remodeling in the gingival crevicular fluid of -- Orthodontic patients / Laura R. Iwasaki and Jeffrey C. Nickel -- Effects of systemic diseases on orthodontic tooth movement / Ze'ev Davidovitch and Vinod Krishnan -- The effect of drugs and diet on orthodontic tooth movement / Vinod Krishnan and Ze'ev Davidovitch -- Biologically and clinically, what are optimal orthodontic forces and how are they applied in selective common malocclusions? / Vincent De Angelis and Ze'ev Davidovitch -- The biological background of relapse of orthodontic tooth movement / Jaap C. Maltha and Anne Marie Kuijpers Jagtman -- Mechanical and biological determinants of iatrogenic injuries in orthodontics / Vinod Krishnan.

Orthodontic Removable Appliances

Author : SS Lohakare
Publisher : Jaypee Brothers,Medical Publishers Pvt. Limited
ISBN 13 : 9788184482898
Total Pages : 86 pages
Book Rating : 4.4/5 (828 download)

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Book Synopsis Orthodontic Removable Appliances by : SS Lohakare

Download or read book Orthodontic Removable Appliances written by SS Lohakare and published by Jaypee Brothers,Medical Publishers Pvt. Limited. This book was released on 2008-12-01 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: - A complete and updated text explained in simplified and easy to grasp manner - Focuses on important orthodontic removable appliances - Covers all retentive, passive and active components, techniques of wire bending, plate construction and finishing, biomechanical consideration, practical management of different misaligned teeth, etc. Useful for students, teachers and practitioners of dentistry

Oral Biofilms

Author : S. Eick
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318068527
Total Pages : 247 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Oral Biofilms by : S. Eick

Download or read book Oral Biofilms written by S. Eick and published by Karger Medical and Scientific Publishers. This book was released on 2020-12-21 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms are highly organized polymicrobial communities that are embedded in an extracellular matrix and formed on natural and artificial surfaces. In the oral cavity, biofilms are formed not only on natural teeth, but also on restorative materials, prosthetic constructions, and dental implants. Oral diseases like caries, gingivitis, periodontitis, and also pulp inflammation are associated with biofilms. This publication is an up-to-date overview on oral biofilms from different clinically relevant perspectives. Experts comprising basic researchers and clinicians report on recent research relating to biofilms - from general summaries to recommendations for daily clinical work. This book covers all aspects of oral biofilms, including models used in the laboratory, biofilms in dental water unit lines, periodontal and peri-implant biofilms, caries-related biofilms, halitosis, endodontic biofilms, and Candida infections, as well as biofilms on dental materials and on orthodontic appliances. Several chapters deal with anti-biofilm therapy, from the efficacy of mechanical methods and the use of antimicrobials, to alternative concepts. This publication is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on biofilms.

Clinical Cases in Orthodontics

Author : Martyn T. Cobourne
Publisher : John Wiley & Sons
ISBN 13 : 140519779X
Total Pages : 457 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Clinical Cases in Orthodontics by : Martyn T. Cobourne

Download or read book Clinical Cases in Orthodontics written by Martyn T. Cobourne and published by John Wiley & Sons. This book was released on 2012-07-23 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wiley-Blackwell's Clinical Cases series is designed to recognize the centrality of clinical cases to the profession by providing actual cases with an academic backbone. Clinical Cases in Orthodontics applies both theory and practice to real-life orthodontic cases in a clinically relevant format. This unique approach supports the new trend in case-based and problem-based learning, thoroughly covering topics ranging from Class I malocclusions to orthognathic surgery. Highly illustrated in full color, Clinical Cases in Orthodontics' format fosters independent learning and prepares the reader for case-based examinations.

Oral Health in America

Author :
Publisher :
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Oral Health in America by :

Download or read book Oral Health in America written by and published by . This book was released on 2000 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dental Caries

Author : Zhou Xuedong
Publisher : Springer
ISBN 13 : 3662474506
Total Pages : 187 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Dental Caries by : Zhou Xuedong

Download or read book Dental Caries written by Zhou Xuedong and published by Springer. This book was released on 2015-10-20 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a well-illustrated and comprehensive guide to the etiology, clinical manifestations, diagnosis, clinical management and prevention of dental caries. Current challenging problems in the field are analyzed and the latest research findings, presented. After an introductory chapter on tooth development, the relationships of biofilm and saliva to dental caries and the significance of the balance between demineralization and remineralization for the development of carious lesions are discussed. Subsequent chapters address the state of the art in diagnosis and treatment, the implications of disease burden for prevention and the association between systemic diseases and dental caries. Dental Caries: Principles and Management is intended for dental school students, practicing dentists and researchers in dentistry.

Congenital Craniofacial Deformities: Genetic and Clinical Aspects

Author : Hanyao Huang
Publisher : Frontiers Media SA
ISBN 13 : 2832537456
Total Pages : 79 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Congenital Craniofacial Deformities: Genetic and Clinical Aspects by : Hanyao Huang

Download or read book Congenital Craniofacial Deformities: Genetic and Clinical Aspects written by Hanyao Huang and published by Frontiers Media SA. This book was released on 2023-10-30 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Caries Management - Science and Clinical Practice

Author : Hendrik Meyer-Lueckel
Publisher : Thieme
ISBN 13 : 3131693819
Total Pages : 846 pages
Book Rating : 4.1/5 (316 download)

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Book Synopsis Caries Management - Science and Clinical Practice by : Hendrik Meyer-Lueckel

Download or read book Caries Management - Science and Clinical Practice written by Hendrik Meyer-Lueckel and published by Thieme. This book was released on 2013-03-20 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the science behind the diseasea comprehensive approach to modern caries management This systematic approach to modern caries management combines new, evidence-based treatment techniques with the scientific underpinnings of caries formationproviding an in-depth review for both clinicians in daily practice and students advancing in the field. Beginning with patho-anatomic changes in the dental hard tissues, Dental Caries: Science and Clinical Practice goes on to cover non-invasive, minimally invasive, and more aggressive interventions based on each stage of the disease. From microbiology and histology to visual, tactile and radiographic diagnosis, risk assessment, preventive measures, and tooth preservation and treatment strategies, the book is packed with valuable clinical information for all dental practitioners. Key Features: Succinctly covers the science behind the disease, with recommendations for treatments based on assessment starting at the microscopic level Written by a team of leading worldwide authorities on caries treatment and managementand utilizing the International Caries Detection and Assessment System (ICDAS) standard throughout Covers the newest treatment techniques, including adhesion technology, fissure sealing and infiltration, caries removal, tooth-colored restorations, and more Demonstrates step-by-step caries procedures in striking, full-color illustrations of adult and pediatric cases Offers the newest thinking on early prevention and behavioral changes in oral health promotion, including the role of diet and nutrition, biofilm management, fluoride use, population-based approaches, and more Shifting to the new paradigm of heal and seal rather than the more invasive drill and fill, this beautifully illustrated text puts scientific principles into clinical action for the best results. It is an essential resource for a complete, proactive approach to caries detection, assessment, treatment, management, and prevention in contemporary dental practice.