Biochemistry of Collagen

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Publisher : Springer Science & Business Media
ISBN 13 : 1475746024
Total Pages : 546 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Biochemistry of Collagen by : Gopalasamudram Ramachandran

Download or read book Biochemistry of Collagen written by Gopalasamudram Ramachandran and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collagen is a fascinating protein not only because of its ubiquitous occurrence in multicellular animals, but also because of its unique chemi cal structure. As the predominant constituent in bone, cartilage, skin, tendon, and tooth, it is not surprising that collagen is of interest to anatomists, biochemists, biomedical engineers, cell biologists, dermatolo gists, dental surgeons, leather chemists, orthopedic surgeons, physiologists, physicians, zoologists, and a host of others. This book was planned to provide an up-to-date comprehensive survey of all aspects of biochemistry of collagen. The recent discovery of genetically distinct collagens with tissue specificity has opened a new era in collagen biochemistry, and Karl Piez discusses this in the opening chapter on primary structure. In the next chapter, Ramachandran and Rama krishnan deal with the molecular structure of collagen, placing special emphasis on the conformational aspects of its polypeptide chains. Follow ing the consideration of primary and secondary structure of collagen, the three-dimensional arrangement of collagen molecules in the fibrils is covered by Miller in Chapter 3. Collagen is generally in the insoluble state in the living organism due to the cross-linking of individual molecules, and Tanzer describes the various aspects of this cross-linkage in Chapter 4. The biosynthesis of collagen is discussed in depth by Prockop and his colleagues.

Collagen

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Publisher : CRC Press
ISBN 13 : 135108769X
Total Pages : 516 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Collagen by : Marcel E. Nimni

Download or read book Collagen written by Marcel E. Nimni and published by CRC Press. This book was released on 2018-01-18 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series was conceived with the idea of integrating current aspects of ongoing research in the collagen field. The book consists of a spectrum of papers which discus divers aspects such as X-ray structure, the thermodynamics and mechanism of fibrillogenesis, and the use of collagen as a biomaterial for the manufacturing of many implantable, sometimes lifesaving, devises.

Biochemistry of Collagens, Laminins and Elastin

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Publisher : Academic Press
ISBN 13 : 0128098996
Total Pages : 274 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Biochemistry of Collagens, Laminins and Elastin by : Morten Karsdal

Download or read book Biochemistry of Collagens, Laminins and Elastin written by Morten Karsdal and published by Academic Press. This book was released on 2016-07-29 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers provides a comprehensive introduction to collagen and structural proteins. Type I collagen is one of the most abundant molecules in the body, playing essential roles in different tissues, particularly bone and skin. A key aspect of type I collagen is its post-translational modifications which are essential for correct synthesis and structural integrity of collagens, for tissue-specific functionality, as well as for application as biomarkers of different pathologies. This volume summarizes current data on key structural proteins (collagens, laminins and elastin), reviews how these molecules affect pathologies, and describes selected modifications of proteins that result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the ECM harbor cryptic signaling functions that may be viewed as endocrine functions. Additionally, it highlights how this knowledge can be exploited to modulate fibrotic disease. - Provides a comprehensive introduction to collagen and structural proteins - Provides insight into emerging analytical technologies that can detect biomarkers of extracellular matrix degradation - Includes a chapter dedicated to the biomarkers of structural proteins - Contains insights into the biochemical interactions and changes to structural composition of proteins in disease states

The Collagens: Biochemistry and Pathophysiology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642761976
Total Pages : 429 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Collagens: Biochemistry and Pathophysiology by : Eugene J. Kucharz

Download or read book The Collagens: Biochemistry and Pathophysiology written by Eugene J. Kucharz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes every manner in which collagen is involved in normal anddisease-altered states of the various organs and systems. In the first part of the book the biochemical aspects of collagens are reviewed, including their structure, heterogeneity, syntheses, and degradation. The main part focuses on the involvement of collagen in bone, cartilage, tendon, muscle, heart, vessels, lungs, liver, skin, eye, ear, teeth, periodontal tissues, kidneys and reproductive, hemopoietic,and nervous systems. The influence of radiation and nutrition on collagen, the role of collagen in neoplasms, the hormonal control of its metabolism, immunobiology and the pharmacology of collagen are also described. The most important feature of the book is the comprehensive review of the medical aspects of collagen, from those known in detail to those only hypothesized including hereditary disorders affecting collagen and so-called collagen diseases. Each chapter reviewsknown or possible mechanisms of collagen involvement and changes in indices of collagen which can be measured in clinical practice to monitor these phenomena. The fact that collagen is involved into the pathophysiology of almost all organs and body systems means that physicians in almost all branches of medicine will find this book of great interest.

Biochemistry of Collagens, Laminins and Elastin

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Author :
Publisher : Elsevier
ISBN 13 : 0443156182
Total Pages : 586 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Biochemistry of Collagens, Laminins and Elastin by : Morten Karsdal

Download or read book Biochemistry of Collagens, Laminins and Elastin written by Morten Karsdal and published by Elsevier. This book was released on 2023-11-07 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry of Collagens, Laminins, and Elastin: Structure, Function and Biomarkers, Third Edition provides current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of these proteins can result in altered signaling properties of the original extracellular matrix (ECM). Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions with ties to endocrine function, and how this knowledge may be used to modulate various pathologies, including fibrotic disease. This new edition has been expanded and revised to incorporate recent research advances. Several new chapters explore a range of chronic diseases in which the ECM and collagens, laminin and elastin are central players in disease modulation, including new chapters on lung, skin and intestinal disease, as well as cancers. The new edition also considers emerging analytical technologies that can detect biomarkers of ECM degradation, with discussion of protein quantification and detecting aging of collagens. - Provides an updated, comprehensive discussion of collagen and related structural proteins - Contains insights into biochemical interactions and changes to structural composition of proteins in disease states - Proves the importance of proteins for collagen assembly, function and durability - Examines details on how collagens play a key role in a range of chronic diseases - Offers approaches for protein quantification and detection of collagen aging

Collagen

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540232728
Total Pages : 272 pages
Book Rating : 4.2/5 (327 download)

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Book Synopsis Collagen by : Jürgen Brinckmann

Download or read book Collagen written by Jürgen Brinckmann and published by Springer Science & Business Media. This book was released on 2005-05-03 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: J. Brinckmann: Collagens at a Glance.- J. Engel, H.P. Bächinger: Structure, Stability and Folding of the Collagen Triple Helix.- S. Ricard-Blum, F. Ruggiero, M. van der Rest: The Collagen Superfamily.- T. Koide, K. Nagata: Collagen Biosynthesis.- J. Myllyharju: Intracellular Post-Translational Modifications of Collagens.- D.S. Greenspan: Biosynthetic Processing of Collagen Molecules.- D.E. Birk, P. Bruckner: Collagen Suprastructures.- D.R. Eyre, J.-J. Wu: Collagen Cross-Links

Structure and function of Collagen types

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Publisher : Elsevier
ISBN 13 : 0323155715
Total Pages : 328 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Structure and function of Collagen types by : Richard Maynes

Download or read book Structure and function of Collagen types written by Richard Maynes and published by Elsevier. This book was released on 2012-12-02 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structure and Function of Collagen Types is a collection of articles that reviews the different types of collagens (Type I to XI). Each article focuses on a particular type of collagen and written by leading investigators in the collagen field. The book begins with a review of the fibril forming collagens (types I, II, and III) and traces the early work on the structure of these collagens to our knowledge of the structure of the collagen genes. This chapter is followed by a detailed description of type IV (basement membrane) collagen. Chapter 3 addresses the biosynthesis and chain assembly of type V collagen. The evidence that type VI collagen is assembled to form tetramers is presented in chapter 4. The subsequent article shows that type VII collagens are assembled to form partially overlapping dimers. Chapter 6 presents the structure of type VIII collagen. Chapters 7, 8, and 9 discuss the structure and characteristics of collagens that are synthesized by cartilaginous tissues and these are designated as type IX, type X, and type XI. The final chapter reviews the recombinant DNA techniques used to investigate collagen structure and the possibility to recognize new collagen types from a cDNA library. Physiologists, cell biologists, and researchers in the field of collagen will find the text very insightful.

Biology of Collagen

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Publisher :
ISBN 13 :
Total Pages : 408 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Biology of Collagen by : Andrus Viidik

Download or read book Biology of Collagen written by Andrus Viidik and published by . This book was released on 1980 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biochemistry of Collagens, Laminins and Elastin

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Author :
Publisher : Academic Press
ISBN 13 : 9780128170687
Total Pages : 0 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis Biochemistry of Collagens, Laminins and Elastin by : Morten Karsdal

Download or read book Biochemistry of Collagens, Laminins and Elastin written by Morten Karsdal and published by Academic Press. This book was released on 2019-05-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are 28 different collagens, with 46 unique chains, which allows for a collagen for each time and place. Some collagens are specialized for basement membrane, whereas others are the central structural component of the interstitial matrix. There are eight collagens among the 20 most abundant proteins in the body, which makes these molecules essential building blocks of tissues. In addition, lessons learned from monogenomic mutations in these proteins result in grave pathologies, exemplifying their importance in development. These molecules, and their post-translationally modified products serve as biomarkers of diseases in a range of pathologies associated with the extracellular matrix. Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers, Second Edition provides researchers and students current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of proteins can result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions that may be viewed as endocrine function, and it highlights how this knowledge can be exploited to modulate fibrotic disease.

Collagen

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387739068
Total Pages : 516 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Collagen by : Peter Fratzl

Download or read book Collagen written by Peter Fratzl and published by Springer Science & Business Media. This book was released on 2008-05-10 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not only does this book provide a comprehensive review of current research advances in collagen structure and mechanics, it also explores this biological macromolecule’s many applications in biomaterials and tissue engineering. Readers gain an understanding of the structure and mechanical behavior of type I collagen and collagen-based tissues in vertebrates across all length scales, from the molecular (nano) to the organ (macro) level.

Collagen

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (87 download)

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Book Synopsis Collagen by :

Download or read book Collagen written by and published by . This book was released on 1988 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bone Morphogenetic Protein And Collagen: An Advances In Tissue Banking Specialist Publication

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Author :
Publisher : World Scientific
ISBN 13 : 9814486388
Total Pages : 169 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Bone Morphogenetic Protein And Collagen: An Advances In Tissue Banking Specialist Publication by : Glyn O Phillips

Download or read book Bone Morphogenetic Protein And Collagen: An Advances In Tissue Banking Specialist Publication written by Glyn O Phillips and published by World Scientific. This book was released on 2004-01-16 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: What are bone morphogenetic proteins (BMPs) and how can they be used in orthopaedic practice? Ever since Urist proposed in 1976 that protein factors from cortical bone appeared to modulate bone healing in animals, there has been a search for these mysterious osteoinductive components. Now that their structure has been elucidated, they have been purified and cloned, and are now available for the improvement of bone healing.The best source of BMPs is demineralised bone. This bone allograft is used to achieve greater osteoinductive capacity. But are the actions of procurement, processing, demineralisation and sterilisation harmful to the BMPs? Unless the BMPs can be assayed, neither their clinical nor their scientific effectiveness can be appraised. All these aspects are logically and scientifically described in this volume. In addition, there is a review of the biochemistry of one of the two main components of bone, namely collagen. This subject is itself a confusing but rapidly growing field. This comprehensive review describes the procedures for building up bone in vivo and in vitro.Bone Morphogenetic Protein and Collagen answers most of the questions of orthopaedic surgeons and tissue bankers on how BMPs can be produced and used to their maximum effectiveness.

Extracellular Matrix Biochemistry

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Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 500 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Extracellular Matrix Biochemistry by : Karl A. Piez

Download or read book Extracellular Matrix Biochemistry written by Karl A. Piez and published by Elsevier Publishing Company. This book was released on 1984 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Collagen

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Publisher : Informa Medical
ISBN 13 : 9780849346002
Total Pages : 320 pages
Book Rating : 4.3/5 (46 download)

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Book Synopsis Collagen by : Marcel E. Nimni

Download or read book Collagen written by Marcel E. Nimni and published by Informa Medical. This book was released on 1988 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and expanded, this Second Edition thoroughly examines the wide array of new and emerging cosmeceutical compounds from antiaging, skin care and repair, moisturizing, and protective compounds to agents with antimicrobial and antiirritant properties.

Connective Tissues

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Publisher : Springer Science & Business Media
ISBN 13 : 3642619320
Total Pages : 469 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Connective Tissues by : R. Fricke

Download or read book Connective Tissues written by R. Fricke and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: connective tissues are essential for the physical functioning of the animals's body. The condition of the various connective tissues is governed by biochemical factors, anabolism and catabolism, that are controlled by specific enzymes. Any change outside the normal range of metabolism, for instance induced by immunological reactions, may induce a pathological disturbance. The result can be acute or chronic inflammation, or loss of normal function, expressed in loosening, dilatation, breaking, wear, stiffness, shrinking, scars, stenosis, and cirrhosis or any other kind of fibrosis. A first step toward improving our understanding of the feedback mecha nism that maintains the biological status and texture of a given connective tissue is to combine what is known about synthesis and enzymatic degradation of the components of fibers and ground substance. Common pathological phenomena like chronic inflammation of immune reactions can be either the result of the cause of disturbances in the sensitive balance of connective tissue metabolism. Nowadays con nective tissues are less and less regarded as brady trophic tissue but rather as a stimulating and many-sided problem of research. Before we can understand the pathogenesis of the connective tissue diseases that result in the destructive processes mentioned above, basic research will be necessary. This research will be furthered by a constant exchange of information and the results of· observations. To promote this exchange of information between scientists, symposia on connective tissue research are organized at regular intervals.

Collagen Biochemistry & Biomechanics

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Publisher : Springer
ISBN 13 :
Total Pages : 326 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis Collagen Biochemistry & Biomechanics by : Marcel E. Nimni

Download or read book Collagen Biochemistry & Biomechanics written by Marcel E. Nimni and published by Springer. This book was released on 1988-02-29 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series was conceived with the idea of integrating current aspects of ongoing research in the collagen field. The book consists of a spectrum of papers which discus divers aspects such as X-ray structure, the thermodynamics and mechanism of fibrillogenesis, and the use of collagen as a biomaterial for the manufacturing of many implantable, sometimes lifesaving, devises.

Biochemistry of Collagen

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Author :
Publisher :
ISBN 13 : 9781475746037
Total Pages : 558 pages
Book Rating : 4.7/5 (46 download)

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Book Synopsis Biochemistry of Collagen by : Gopalasamudram Ramachandran

Download or read book Biochemistry of Collagen written by Gopalasamudram Ramachandran and published by . This book was released on 2014-01-15 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: