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Closed Loop Control Of Blood Glucose
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Book Synopsis Closed-Loop Control of Blood Glucose by : Frederick Chee
Download or read book Closed-Loop Control of Blood Glucose written by Frederick Chee and published by Springer. This book was released on 2007-10-24 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents closed-loop blood glucose control in a simple manner, which includes the hardware and "software" components that make up the control system. It provides examples on how mathematical models are formulated as well as the control algorithms that stem from mathematical exercises. The book also describes the basic physiology of blood glucose regulation during fasting and meal from a functional level.
Book Synopsis Design and implementation of a closed-loop blood glucose control system in patients with type 1 diabetes by : Fabian Mauricio León Vargas
Download or read book Design and implementation of a closed-loop blood glucose control system in patients with type 1 diabetes written by Fabian Mauricio León Vargas and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Closed-Loop Control of Blood Glucose by : Frederick Chee
Download or read book Closed-Loop Control of Blood Glucose written by Frederick Chee and published by Springer Science & Business Media. This book was released on 2007-10-01 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents closed-loop blood glucose control in a simple manner, which includes the hardware and "software" components that make up the control system. It provides examples on how mathematical models are formulated as well as the control algorithms that stem from mathematical exercises. The book also describes the basic physiology of blood glucose regulation during fasting and meal from a functional level.
Book Synopsis Closed-loop System for Blood Glucose Level Control by : Evgeniia Litinskaia
Download or read book Closed-loop System for Blood Glucose Level Control written by Evgeniia Litinskaia and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Closed-loop Blood Glucose Control Device by : Joel Broida
Download or read book Closed-loop Blood Glucose Control Device written by Joel Broida and published by . This book was released on 1983 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Explicitly Minimizing Clinical Risk Through Closed-loop Control of Blood Glucose in Patients with Type 1 Diabetes Mellitus by : Fraser Murray Coulter Cameron
Download or read book Explicitly Minimizing Clinical Risk Through Closed-loop Control of Blood Glucose in Patients with Type 1 Diabetes Mellitus written by Fraser Murray Coulter Cameron and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Type 1 Diabetes Mellitus or Juvenile Onset Diabetes is currently a permanent, incurable disease that removes the ability of the patient's body to control blood glucose levels. This loss of automatic control greatly increases the patient's exposure to clinical risks of high and low blood glucose levels. These risks can be mitigated through tight, regulation of blood glucose levels using insulin injections, but only at the price of paying frequent attention to the blood glucose levels and manually providing accurate dosing decisions. This can be very trying for all patients, especially teenagers and children. Recent technological advances enable automatic external regulation of patient's blood glucose levels. Pumps can infuse insulin into the subcutaneous tissue to lower blood glucose levels. Continuous glucose monitors can sense subcutaneous glucose levels, specifically the rises caused by meals and the drops caused by insulin. This has caused a flurry of control and modeling research, in the hopes of mitigating the clinical risk without the price of constant human attention. The most common approach, and the one taken here, is to use model predictive control, where the predictions from a model of glucose dynamics are optimized against a cost function using the future insulin injections. We directly minimize the asymmetric clinical risk instead, and recognize that our control authority (the potential effects of injecting insulin) is largely limited to reducing the blood glucose level. We further consider likely future blood glucose measurements, since we both respond better to positive disturbances than negative ones, and because negative disturbances are more risky. Also, we explicitly estimate the uncertainty of predictions, since glucose dynamics incorporate uncertainty from the complex biology, stochastic patient behaviour, and extrapolation. More uncertainty should mean more cautious insulin injection. Lastly, since meals occur faster than insulin acts and can raise the blood glucose by 2 to 4 times the width of the acceptable range, this work develops a novel Bayesian framework for detecting meals and estimating their effects. This work improves prediction root mean squared error by 20% relative to predictions excluding meals for prediction horizons from 1 to 4 hours and improves robustness to meals. These prediction improvements alone reduce the avoidable clinical risk by 38% relative to predictions excluding meals. When the improvements to the predictions are combined with minimizing clinical risk under uncertainty and measurement anticipation the avoidable clinical risk is reduced by 30% relative to a published MPC controller that has privileged information and tunes independently for each patient.
Book Synopsis Evaluation of the Subcutaneous Route for Closed-loop Control of Glucose by : Zlatko Trajanoski
Download or read book Evaluation of the Subcutaneous Route for Closed-loop Control of Glucose written by Zlatko Trajanoski and published by . This book was released on 1995 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Managing Diabetes and Hyperglycemia in the Hospital Setting by : Boris Draznin
Download or read book Managing Diabetes and Hyperglycemia in the Hospital Setting written by Boris Draznin and published by American Diabetes Association. This book was released on 2016-05-20 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the number of patients with diabetes increases annually, it is not surprising that the number of patients with diabetes who are admitted to the hospital also increases. Once in the hospital, patients with diabetes or hyperglycemia may be admitted to the Intensive Care Unit, require urgent or elective surgery, enteral or parenteral nutrition, intravenous insulin infusion, or therapies that significantly impact glycemic control (e.g., steroids). Because many clinical outcomes are influenced by the degree of glycemic control, knowledge of the best practices in inpatient diabetes management is extremely important. The field of inpatient management of diabetes and hyperglycemia has grown substantially in the last several years. This body of knowledge is summarized in this book, so it can reach the audience of hospitalists, endocrinologists, nurses and other team members who take care of hospitalized patients with diabetes and hyperglycemia.
Book Synopsis Microelectronics, Electromagnetics and Telecommunications by : Jaume Anguera
Download or read book Microelectronics, Electromagnetics and Telecommunications written by Jaume Anguera and published by Springer. This book was released on 2018-01-25 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume contains 94 best selected research papers presented at the Third International Conference on Micro Electronics, Electromagnetics and Telecommunications (ICMEET 2017) The conference was held during 09-10, September, 2017 at Department of Electronics and Communication Engineering, BVRIT Hyderabad College of Engineering for Women, Hyderabad, Telangana, India. The volume includes original and application based research papers on microelectronics, electromagnetics, telecommunications, wireless communications, signal/speech/video processing and embedded systems.
Book Synopsis Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI Approach by : Anirudh Nath
Download or read book Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI Approach written by Anirudh Nath and published by Academic Press. This book was released on 2022-08-13 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonlinear Control for Blood Glucose Regulation of Diabetic Patients: An LMI-Based Approach exposes readers to the various existing mathematical models that define the dynamics of glucose-insulin for Type 1 diabetes patients. After providing insights into the mathematical model of patients, the authors discuss the need and emergence of new control techniques that can lead to further development of an artificial pancreas. The book presents various nonlinear control techniques to address the challenges that Type 1 diabetic patients face in maintaining their blood glucose level in the safe range (70-180 mg/dl). The closed-loop solution provided by the artificial pancreas depends mainly on the effectiveness of the control algorithm, which acts as the brain of the system. APS control algorithms require a mathematical model of the gluco-regulatory system of the T1D patients for their design. Since the gluco-regulatory system is inherently nonlinear and largely affected by external disturbances and parametric uncertainty, developing an accurate model is very difficult. Presents control-oriented modeling of the gluco-regulatory system of Type 1 diabetic patients using input-output data Demonstrates the design of a robust insulin delivery mechanism utilizing state estimation information with parametric uncertainties and exogenous disturbance in the framework of Linear Matrix Inequality (LMI) Introduces readers to the relevance and effectiveness of powerful nonlinear controllers for the Artificial Pancreas Provides the first book on LMI-based nonlinear control techniques for the Artificial Pancreas
Book Synopsis Control Applications for Biomedical Engineering Systems by : Ahmad Taher Azar
Download or read book Control Applications for Biomedical Engineering Systems written by Ahmad Taher Azar and published by Academic Press. This book was released on 2020-01-22 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Control Applications for Biomedical Engineering Systems presents different control engineering and modeling applications in the biomedical field. It is intended for senior undergraduate or graduate students in both control engineering and biomedical engineering programs. For control engineering students, it presents the application of various techniques already learned in theoretical lectures in the biomedical arena. For biomedical engineering students, it presents solutions to various problems in the field using methods commonly used by control engineers. Points out theoretical and practical issues to biomedical control systems Brings together solutions developed under different settings with specific attention to the validation of these tools in biomedical settings using real-life datasets and experiments Presents significant case studies on devices and applications
Book Synopsis Hypoglycemia in Diabetes by : Philip Cryer
Download or read book Hypoglycemia in Diabetes written by Philip Cryer and published by American Diabetes Association. This book was released on 2016-07-12 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for diabetes researchers and medical professionals who work closely with patients with diabetes, this newly updated and expanded edition provides new perspectives and direct insight into the causes and consequences of this serious medical condition from one of the foremost experts in the field. Using the latest scientific and medical developments and trends, readers will learn how to identify, prevent, and treat this challenging phenomenon within the parameters of the diabetes care regimen.
Book Synopsis Prediction Methods for Blood Glucose Concentration by : Harald Kirchsteiger
Download or read book Prediction Methods for Blood Glucose Concentration written by Harald Kirchsteiger and published by Springer. This book was released on 2015-11-24 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book tackles the problem of overshoot and undershoot in blood glucose levels caused by delay in the effects of carbohydrate consumption and insulin administration. The ideas presented here will be very important in maintaining the welfare of insulin-dependent diabetics and avoiding the damaging effects of unpredicted swings in blood glucose – accurate prediction enables the implementation of counter-measures. The glucose prediction algorithms described are also a key and critical ingredient of automated insulin delivery systems, the so-called “artificial pancreas”. The authors address the topic of blood-glucose prediction from medical, scientific and technological points of view. Simulation studies are utilized for complementary analysis but the primary focus of this book is on real applications, using clinical data from diabetic subjects. The text details the current state of the art by surveying prediction algorithms, and then moves beyond it with the most recent advances in data-based modeling of glucose metabolism. The topic of performance evaluation is discussed and the relationship of clinical and technological needs and goals examined with regard to their implications for medical devices employing prediction algorithms. Practical and theoretical questions associated with such devices and their solutions are highlighted. This book shows researchers interested in biomedical device technology and control researchers working with predictive algorithms how incorporation of predictive algorithms into the next generation of portable glucose measurement can make treatment of diabetes safer and more efficient.
Book Synopsis Physical Activity and Type 1 Diabetes by : Johan Henrik Jendle
Download or read book Physical Activity and Type 1 Diabetes written by Johan Henrik Jendle and published by Frontiers Media SA. This book was released on 2020-01-17 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis A Control Study Approach to Regulate Blood Glucose Level by : Pratik Mehta
Download or read book A Control Study Approach to Regulate Blood Glucose Level written by Pratik Mehta and published by . This book was released on 2018 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Instrumentation is an exciting field to discover and explore. Diabetes mellitus is one of the critical research areas which has been addressed for decades. The development of the constant glucose measuring devices and insulin pumps give an expectation for better well-being. The pancreas in the body plays a dynamic part in regulating the glucose level in blood. The function of the pancreas to produce insulin enzymes. The deficiency of the pancreas causes to rise in blood glucose level. Many research scientists are working on diagnosing and treating this diabetes mellitus disease. The mathematical model adopted in this work represents the dynamics of glucose and insulin. The name of model is extended Bergman Minimal Model. With this model, a closed loop feedback control system of blood glucose-insulin is developed to normalize the glucose level in blood. The developed system is implemented and analyzed with a software tool called MATLAB. The PID control and Fuzzy control methods are designed for exogenous insulin infusion pumps. These control methods are applied to the developed system to maintain the blood glucose level in desired range. Simulations shows that both designed control methods can keep the blood glucose level in desired range. However, the PID control method able to achieve the setpoint while the fuzzy control is never able to reach the setpoint value. With the PID control method, the output is oscillatory in nature to give blood glucose value before coming to the setpoint value. The fuzzy controller gives small overshoot in output but within the normal range.
Book Synopsis A Chinese Survey on the Effect and Experience of DIY Hybrid Closed-loop System in Patients with Type 1 Diabetes by : Ling-wang An
Download or read book A Chinese Survey on the Effect and Experience of DIY Hybrid Closed-loop System in Patients with Type 1 Diabetes written by Ling-wang An and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Background: In recent years, many open resources can be found in the open communities to help patients with type 1 diabetes make their own hybrid closed loop system (Do it by yourself, DIY) by using the existing insulin pump and continuous blood glucose monitoring system (CGMS). Insulin pumpu2019s basal insulin can be automatically adjusted to keep glucose in a stable range based on predicted future glucose levels. Nightscout software is used to implement remote data transmission and control. Softwares called.
Book Synopsis A CONTROLLER FOR BLOOD GLUCOSE REGULATION BASED ON MODULATION OF INSULIN SENSITIVITY IN PEOPLE WITH TYPE I DIABETES. by :
Download or read book A CONTROLLER FOR BLOOD GLUCOSE REGULATION BASED ON MODULATION OF INSULIN SENSITIVITY IN PEOPLE WITH TYPE I DIABETES. written by and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: BackgroundDespite new technology developed for diabetes management, glucose control remains suboptimal especially during meals. In recent years, bioelectronic medicine has shown promise for management of glucose fluctuations by controlling the insulin sensitivity (SI) through modulation of neural pathways. Within this context, in this work we present a proof-of-concept of the first closed-loop system that incorporates SI as an additional control variable for glucose regulation. MethodThe coordinated bi-hormonal bio-inspired controller (BiAP) for type 1 diabetes mellitus (T1DM) was extended by including a standard proportional-derivative (sPD) controller to determine the optimal SI from continuous blood glucose measurements. The tuning of the parameters of the resulting hybrid hormonal-insulin sensitivity glucose (InSiG) controller, and a comparison in performance with BiAP, were carried out on a virtual population of subjects with T1DM (n=20, 10 adults and 10 adolescents). A statistical analysis of the differences between controllers was performed using the parametric student paired t-test (u03b1 = 0.01). ResultsInSiG significantly increased the percentage of time glucose levels were within target (70-180 md/dL) to 99.4u00b11.0% in adults and 96.4u00b14.6% in adolescents (p
