Clinical and Translational Science

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Publisher : Academic Press
ISBN 13 : 012802111X
Total Pages : 812 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Clinical and Translational Science by : David Robertson

Download or read book Clinical and Translational Science written by David Robertson and published by Academic Press. This book was released on 2016-11-25 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and new biostatistical approaches, and investigative tools. It presents complete instruction and guidance from fundamental principles, approaches, and infrastructure, especially for human genetics and genomics, human pharmacology, research in special populations, the societal context of human research, and the future of human research. The book moves on to discuss legal, social, and ethical issues, and concludes with a discussion of future prospects, providing readers with a comprehensive view of this rapidly developing area of science. Introduces novel physiological and therapeutic strategies for engaging the fastest growing scientific field in both the private sector and academic medicine Brings insights from international leaders into the discipline of clinical and translational science Addresses drug discovery, drug repurposing and development, innovative and improved approaches to go/no-go decisions in drug development, and traditional and innovative clinical trial designs

Fundamentals of Clinical Data Science

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Publisher : Springer
ISBN 13 : 3319997130
Total Pages : 219 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Fundamentals of Clinical Data Science by : Pieter Kubben

Download or read book Fundamentals of Clinical Data Science written by Pieter Kubben and published by Springer. This book was released on 2018-12-21 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book comprehensively covers the fundamentals of clinical data science, focusing on data collection, modelling and clinical applications. Topics covered in the first section on data collection include: data sources, data at scale (big data), data stewardship (FAIR data) and related privacy concerns. Aspects of predictive modelling using techniques such as classification, regression or clustering, and prediction model validation will be covered in the second section. The third section covers aspects of (mobile) clinical decision support systems, operational excellence and value-based healthcare. Fundamentals of Clinical Data Science is an essential resource for healthcare professionals and IT consultants intending to develop and refine their skills in personalized medicine, using solutions based on large datasets from electronic health records or telemonitoring programmes. The book’s promise is “no math, no code”and will explain the topics in a style that is optimized for a healthcare audience.

Basic Science Methods for Clinical Researchers

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Publisher : Academic Press
ISBN 13 : 012803078X
Total Pages : 383 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Basic Science Methods for Clinical Researchers by : Morteza Jalali

Download or read book Basic Science Methods for Clinical Researchers written by Morteza Jalali and published by Academic Press. This book was released on 2017-03-31 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow’s clinician scientists and future leaders in discovery science. Serves as a helpful guide for clinical researchers who lack a conventional science background Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)

Understanding Clinical Research

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Publisher : McGraw Hill Professional
ISBN 13 : 0071792651
Total Pages : 262 pages
Book Rating : 4.0/5 (717 download)

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Book Synopsis Understanding Clinical Research by : Renato D. Lopes

Download or read book Understanding Clinical Research written by Renato D. Lopes and published by McGraw Hill Professional. This book was released on 2013-05-22 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete guide to understanding and applying clinical research results Ideal for both researchers and healthcare providers Understanding Clinical Research addresses both the operational challenges of clinical trials and the needs of clinicians to comprehend the nuances of research methods to accurately analyze study results. This timely resource covers all aspects of clinical trials--from study design and statistics to regulatory oversight--and it delivers a detailed yet streamlined overview of must-know research topics. The text features an accessible three-part organization that traces the evolution of clinical research and explains the bedrock principles and unique challenges of clinical experimentation and observational research. Reinforcing this content are real-life case examples--drawn from the authors' broad experience--that put chapter concepts into action and contribute to a working knowledge of integral research techniques. FEATURES: The most definitive guide to promoting excellence in clinical research, designed to empower healthcare providers to assess a study's strengths and weaknesses with confidence and apply this knowledge to optimize patient outcomes In-depth coverage of fundamental research methods and protocols from preeminent authorities provides readers with an instructive primer and a springboard for ongoing clinical research education Clear, comprehensive three-part organization: Section One: Evolution of Clinical Research offers a succinct history of clinical trials, drug regulations, and the role of the FDA while covering the impact of information technology and academic research organizations Section Two: Principles of Clinical Experimentation takes you through the typical phases of clinical trials in the development of medical products, from initial human subject research to postapproval surveillance studies Section Three: Observational Research highlights the underlying principles, pitfalls, and methods for case-control studies, cohort studies, registries, and subgroup analyses within randomized trials

Advancing the Nation's Health Needs

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Publisher : National Academies Press
ISBN 13 : 0309094275
Total Pages : 187 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Advancing the Nation's Health Needs by : National Research Council

Download or read book Advancing the Nation's Health Needs written by National Research Council and published by National Academies Press. This book was released on 2005-08-13 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report is the twelfth assessment of the National Institutes of Health National Research Service Awards program. The research training needs of the country in basic biomedical, clinical, and behavioral and social sciences are considered. Also included are the training needs of oral health, nursing, and health services research. The report has been broadly constructed to take into account the rapidly evolving national and international health care needs. The past and present are analyzed, and predictions with regard to future needs are presented.

Designing Clinical Research

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451165854
Total Pages : 388 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Designing Clinical Research by : Stephen B. Hulley

Download or read book Designing Clinical Research written by Stephen B. Hulley and published by Lippincott Williams & Wilkins. This book was released on 2011-11-30 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designing Clinical Research sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology—including molecular and genetic clinical research—and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing. All chapters have been thoroughly revised, updated, and made more user-friendly.

Principles and Practice of Clinical Research

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Publisher : Elsevier
ISBN 13 : 0080489567
Total Pages : 447 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Principles and Practice of Clinical Research by : John I. Gallin

Download or read book Principles and Practice of Clinical Research written by John I. Gallin and published by Elsevier. This book was released on 2011-04-28 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers. *Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research*Delves into data management and addresses how to collect data and use it for discovery*Contains valuable, up-to-date information on how to obtain funding from the federal government

Clinical Research Computing

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Publisher : Academic Press
ISBN 13 : 012803145X
Total Pages : 242 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Clinical Research Computing by : Prakash Nadkarni

Download or read book Clinical Research Computing written by Prakash Nadkarni and published by Academic Press. This book was released on 2016-04-29 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Research Computing: A Practitioner’s Handbook deals with the nuts-and-bolts of providing informatics and computing support for clinical research. The subjects that the practitioner must be aware of are not only technological and scientific, but also organizational and managerial. Therefore, the author offers case studies based on real life experiences in order to prepare the readers for the challenges they may face during their experiences either supporting clinical research or supporting electronic record systems. Clinical research computing is the application of computational methods to the broad field of clinical research. With the advent of modern digital computing, and the powerful data collection, storage, and analysis that is possible with it, it becomes more relevant to understand the technical details in order to fully seize its opportunities. Offers case studies, based on real-life examples where possible, to engage the readers with more complex examples Provides studies backed by technical details, e.g., schema diagrams, code snippets or algorithms illustrating particular techniques, to give the readers confidence to employ the techniques described in their own settings Offers didactic content organization and an increasing complexity through the chapters

Evidence-Based Practice in Action

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Publisher : Guilford Publications
ISBN 13 : 1462539769
Total Pages : 465 pages
Book Rating : 4.4/5 (625 download)

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Book Synopsis Evidence-Based Practice in Action by : Sona Dimidjian

Download or read book Evidence-Based Practice in Action written by Sona Dimidjian and published by Guilford Publications. This book was released on 2019-08-30 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The evidence-based practice (EBP) movement has always been about implementing optimal health care practices. Practitioners have three primary roles they can play in relation to the research evidence in EBP: scientists, systematic reviewers, and research consumers. Learning EBP is an acculturation process begun during professional training that seamlessly integrates research and practice"--Provided by publisher.

A Concise Review of Clinical Laboratory Science

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451159706
Total Pages : 676 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis A Concise Review of Clinical Laboratory Science by : Joel Hubbard

Download or read book A Concise Review of Clinical Laboratory Science written by Joel Hubbard and published by Lippincott Williams & Wilkins. This book was released on 2011-12-21 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Second Edition offers a concise review of all areas of clinical lab science, including the standard areas, such as hematology, chemistry, hemostasis, immunohematology, clinical microbiology, parasitology, urinalysis and more, as well as lab management, lab government regulations, and quality assurance. A companion website offers 35 case studies, an image bank of color images, and a quiz bank with 500 questions in certification format.

The Science and Clinical Application of Manual Therapy

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Publisher : Elsevier Health Sciences
ISBN 13 : 0702049956
Total Pages : 334 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis The Science and Clinical Application of Manual Therapy by : Hollis H. King

Download or read book The Science and Clinical Application of Manual Therapy written by Hollis H. King and published by Elsevier Health Sciences. This book was released on 2010-09-18 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Science and Clinical Application of Manual Therapy is a multi-disciplinary, international reference book based on work by the top basic science researchers and clinical researchers in the area of Manual Therapy and Manual Medicine (MT/MM). The first book to bring together research on the benefits of MT/MM beyond the known effects on musculoskeletal disorders, the volume presents evidence of the benefit of MT/MM in treating systemic disorders. This book makes a powerful case for how MT/MM affects the central nervous system and the autonomic effector systems (the circulatory, respiratory, gastrointestinal systems, and pelvic organs) which impact on a person’s health. The volume covers how MT/MM works and details the conditions – such as chronic skeletal and visceral pain diseases, asthma, pneumonia, and cardiovascular deregulation – that can benefit from it. Longstanding theoretical models of MT/MM mechanisms are critically assessed in the light of current understanding of physiological and neurophysiological function, and the influences of psychological and cortical processes on the effects of MT/MM are explored. The book, which is divided into four main sections, will appeal to osteopathic physicians, osteopaths, chiropractors, physical therapists and massage therapists, as well as all body workers/health practitioners who use their hands in health care. It will be of particular value to all practitioners involved in treatment of chronic pain disorders as well as those involved in basic and clinical research in this field. Authored by the leading multidisciplinary basic science and clinical researchers from throughout the world Describes research confirming benefit of MT for musculoskeletal disorders (which helps provide a rational for greater utilization of manual therapy and reimbursement for this healthcare service) Presents the latest findings on the beneficial effect of MT on systemic disorders including asthma, pneumonia, otitis media, heart rate dysfunction and GI disturbance Critically assesses longstanding theoretical models of MT/MM mechanisms with respect to the current understanding of physiological and neurophysiological function Explores the influences of psychological and cortical processes on the effects of MT/MM, including the effect of placebo Uniquely presents research findings from all the manual therapy professions and scientists making the case for the benefits of MT The symposium from which the book was derived was supported by the NIH National Center for Complimentary and Alternative Medicine

Science and Pseudoscience in Clinical Psychology, First Edition

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Publisher : Guilford Press
ISBN 13 : 1462509029
Total Pages : 498 pages
Book Rating : 4.4/5 (625 download)

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Book Synopsis Science and Pseudoscience in Clinical Psychology, First Edition by : Scott O. Lilienfeld

Download or read book Science and Pseudoscience in Clinical Psychology, First Edition written by Scott O. Lilienfeld and published by Guilford Press. This book was released on 2012-12-18 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first major text designed to help professionals and students evaluate the merits of popular yet controversial practices in clinical psychology, differentiating those that can stand up to the rigors of science from those that cannot. Leading researchers review widely used therapies for alcoholism, infantile autism, ADHD, and posttraumatic stress disorder; herbal remedies for depression and anxiety; suggestive techniques for memory recovery; and self-help models. Other topics covered include issues surrounding psychological expert testimony, the uses of projective assessment techniques, and unanswered questions about dissociative identity disorder. Providing knowledge to guide truly accountable mental health practice, the volume also imparts critical skills for designing and evaluating psychological research programs. It is ideal for use in advanced undergraduate- and graduate-level courses in clinical psychology, psychotherapy, and evidence-based practice.

Health Care Delivery and Clinical Science

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Publisher :
ISBN 13 : 9781522539261
Total Pages : 0 pages
Book Rating : 4.5/5 (392 download)

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Book Synopsis Health Care Delivery and Clinical Science by : Information Resources Management Association

Download or read book Health Care Delivery and Clinical Science written by Information Resources Management Association and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of better processes to provide proper healthcare has enhanced contemporary society. By implementing effective collaborative strategies, this ensures proper quality and instruction for both the patient and medical practitioners. Health Care Delivery and Clinical Science: Concepts, Methodologies, Tools, and Applications is a comprehensive reference source for the latest scholarly material on emerging strategies and methods for delivering optimal healthcare and examines the latest techniques and methods of clinical science. Highlighting a range of pertinent topics such as medication management, health literacy, and patient engagement, this multi-volume book is ideally designed for professionals, practitioners, researchers, academics, and graduate students interested in healthcare delivery and clinical science.

The Great Ideas of Clinical Science

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Publisher : Taylor & Francis
ISBN 13 : 113593018X
Total Pages : 447 pages
Book Rating : 4.1/5 (359 download)

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Book Synopsis The Great Ideas of Clinical Science by : Scott O. Lilienfeld

Download or read book The Great Ideas of Clinical Science written by Scott O. Lilienfeld and published by Taylor & Francis. This book was released on 2012-12-06 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: The idea that there is a fundamental rift between researchers and practitioners should not come as a surprise to anyone familiar with the current literature, trends, and general feelings in the field of clinical psychology. Central to this scientist-practitioner gap is an underlying disagreement over the nature of knowledge - namely that while some individuals point to research studies as the foundation of truth, others argue that clinical experience offers a more adequate understanding of the causes, assessment, and treatment of mental illness. The Great Ideas of Clinical Science is an ambitious attempt to dig beneath these fundamental differences, and reintroduce the reader to unifying principles often overlooked by students and professionals alike. The editors have identified 17 such universals, and have pulled together a group of the most prolific minds in the field to present the philosophical, methodological, and conceptual ideas that define the state of the field. Each chapter focuses on practical as well as conceptual points, offering valuable insight to practicing clinicians, researchers, and teachers of any level of experience. Written for student, practitioner, researcher, and educated layperson, this integrative volume aims to facilitate communication among all mental health professionals and to narrow the scientist-practitioner gap.

Foundations of Clinical Research

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Publisher :
ISBN 13 : 9780803646575
Total Pages : 0 pages
Book Rating : 4.6/5 (465 download)

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Book Synopsis Foundations of Clinical Research by : Leslie Gross Portney

Download or read book Foundations of Clinical Research written by Leslie Gross Portney and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Draw upon the foundations necessary for finding and interpreting research evidence across all healthcare professions. Revised to reflect the most current changes in the field of clinical research in rehabilitation and medicine, you'll find a growing emphasis on evidence-based practice (EBP) as well as new vocabulary that is being integrated into research and practice across disciplines.

Understanding Pharmacoepidemiology

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Publisher : McGraw Hill Professional
ISBN 13 : 0071766677
Total Pages : 208 pages
Book Rating : 4.0/5 (717 download)

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Book Synopsis Understanding Pharmacoepidemiology by : Yi Yang

Download or read book Understanding Pharmacoepidemiology written by Yi Yang and published by McGraw Hill Professional. This book was released on 2010-12-31 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise introduction to the study of medication utilization and safety in large populations of people Understanding Pharmacoepidemiology is a clear, engagingly written roadmap to mastering the important concepts and methods of pharmacoepidemiology. It explains what pharmacoepidemiology is, how pharmacoepidemiology studies are conducted, and how to interpret findings. You will learn the importance of pharmacoepidemiology, basic terminology used in research, and the data sources, study designs, and statistical analyses employed in pharmacoepidemiology research. Upon completing Understanding Pharmacoepidemiology you will have a better understanding of how to evaluate the associations between medication utilization and outcomes. Each chapter includes these valuable learning aids: A list of learning objectives Case studies or examples Discussion questions Tables and Figures You will also find a glossary of important words and terms. The content you need to understand the concepts and methods of pharmacoepidemiology: Introduction to Pharmacoepidemiology: Principles of Epidemiology Applied to the Study of Medication Use, Study Designs in Pharmacoepidemiology: Using Secondary Data in Pharmacoepidemiology; Biostatistics and Pharmacoepidemiology: Other Methodological Issues; Evaluation of Pharmacoepidemiology Literature; Medication Utilization Patterns; Medication Safety and Pharmacovigilance; and FDA Perspectives on Post-market Drug Safety.

Clinical Laboratory Science Review

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Publisher :
ISBN 13 : 9780967043432
Total Pages : 270 pages
Book Rating : 4.0/5 (434 download)

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Book Synopsis Clinical Laboratory Science Review by :

Download or read book Clinical Laboratory Science Review written by and published by . This book was released on 2015 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: