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Clinical Relevance Of Genetic Factors In Pulmonary Diseases
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Book Synopsis Clinical Relevance of Genetic Factors in Pulmonary Diseases by : Takeshi Kaneko
Download or read book Clinical Relevance of Genetic Factors in Pulmonary Diseases written by Takeshi Kaneko and published by Springer. This book was released on 2018-07-12 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the underlying genetic basis of common pulmonary diseases and discusses their pathogenesis and pathophysiology. These insights provide the basis for understanding different subtypes and phonotypes, and will promote better treatment strategies and individualized medicine. The book provides new and valuable information for the development of the areas of study, as well as practical guidelines for clinicians engaged in treating pulmonary diseases. This volume of the Respiratory Disease Series – Diagnostic Tools and Disease Managements will broaden the understanding of beginning and experienced researchers and clinicians who treat pulmonary diseases. Moreover, residents and clinicians engaged in medical oncology will find it a valuable guide to support them in their day-to-day work.
Author :United States. Public Health Service. Office of the Surgeon General Publisher : ISBN 13 : Total Pages :728 pages Book Rating :4.:/5 (318 download)
Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Book Synopsis Network Medicine by : Joseph Loscalzo
Download or read book Network Medicine written by Joseph Loscalzo and published by Harvard University Press. This book was released on 2017-02-01 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Big data, genomics, and quantitative approaches to network-based analysis are combining to advance the frontiers of medicine as never before. Network Medicine introduces this rapidly evolving field of medical research, which promises to revolutionize the diagnosis and treatment of human diseases. With contributions from leading experts that highlight the necessity of a team-based approach in network medicine, this definitive volume provides readers with a state-of-the-art synthesis of the progress being made and the challenges that remain. Medical researchers have long sought to identify single molecular defects that cause diseases, with the goal of developing silver-bullet therapies to treat them. But this paradigm overlooks the inherent complexity of human diseases and has often led to treatments that are inadequate or fraught with adverse side effects. Rather than trying to force disease pathogenesis into a reductionist model, network medicine embraces the complexity of multiple influences on disease and relies on many different types of networks: from the cellular-molecular level of protein-protein interactions to correlational studies of gene expression in biological samples. The authors offer a systematic approach to understanding complex diseases while explaining network medicine’s unique features, including the application of modern genomics technologies, biostatistics and bioinformatics, and dynamic systems analysis of complex molecular networks in an integrative context. By developing techniques and technologies that comprehensively assess genetic variation, cellular metabolism, and protein function, network medicine is opening up new vistas for uncovering causes and identifying cures of disease.
Book Synopsis SARS, MERS and other Viral Lung Infections by : David S. Hui
Download or read book SARS, MERS and other Viral Lung Infections written by David S. Hui and published by European Respiratory Society. This book was released on 2016-06-01 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viral respiratory tract infections are important and common causes of morbidity and mortality worldwide. In the past two decades, several novel viral respiratory infections have emerged with epidemic potential that threaten global health security. This Monograph aims to provide an up-to-date and comprehensive overview of severe acute respiratory syndrome, Middle East respiratory syndrome and other viral respiratory infections, including seasonal influenza, avian influenza, respiratory syncytial virus and human rhinovirus, through six chapters written by authoritative experts from around the globe.
Book Synopsis A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases by : Institute of Medicine
Download or read book A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2011-08-26 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic diseases are common and costly, yet they are also among the most preventable health problems. Comprehensive and accurate disease surveillance systems are needed to implement successful efforts which will reduce the burden of chronic diseases on the U.S. population. A number of sources of surveillance data-including population surveys, cohort studies, disease registries, administrative health data, and vital statistics-contribute critical information about chronic disease. But no central surveillance system provides the information needed to analyze how chronic disease impacts the U.S. population, to identify public health priorities, or to track the progress of preventive efforts. A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases outlines a conceptual framework for building a national chronic disease surveillance system focused primarily on cardiovascular and chronic lung diseases. This system should be capable of providing data on disparities in incidence and prevalence of the diseases by race, ethnicity, socioeconomic status, and geographic region, along with data on disease risk factors, clinical care delivery, and functional health outcomes. This coordinated surveillance system is needed to integrate and expand existing information across the multiple levels of decision making in order to generate actionable, timely knowledge for a range of stakeholders at the local, state or regional, and national levels. The recommendations presented in A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases focus on data collection, resource allocation, monitoring activities, and implementation. The report also recommends that systems evolve along with new knowledge about emerging risk factors, advancing technologies, and new understanding of the basis for disease. This report will inform decision-making among federal health agencies, especially the Department of Health and Human Services; public health and clinical practitioners; non-governmental organizations; and policy makers, among others.
Book Synopsis The Normal Lung by : John Frederic Murray
Download or read book The Normal Lung written by John Frederic Murray and published by W.B. Saunders Company. This book was released on 1986 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Lung Development by : Claude Gaultier
Download or read book Lung Development written by Claude Gaultier and published by Springer. This book was released on 2013-05-27 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge about the mechanisms of lung development has been growing rapidly, especially with regard to cellular and molecular aspects of growth and differentiation. This authoritative international volume reviews key aspects of lung development in health and disease by providing a comprehensive review of the complex series of cellular and molecular interactions required for lung development. It covers such topics as pulmonary hypoplasia, effects of malnutrition, and pulmaonary angiogenesis. An indispensable reference for all those involved in studying or treating lung disease in neonates and children, the book offers a unique view of the development of this essential organ.
Book Synopsis Interstitial Lung Disease E-Book by : Harold R Collard
Download or read book Interstitial Lung Disease E-Book written by Harold R Collard and published by Elsevier Health Sciences. This book was released on 2017-02-18 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinically focused and designed to provide a to-the-point overview, Interstitial Lung Disease, by Drs. Talmadge King, Harold Collard, and Luca Richeldi, bring you up to date with increased understanding, new treatment protocols, and recent advances in the field. Written by contributing specialists who are global experts in their respective areas, this one-stop reference provides pulmonologists, intensivists, internal medicine physicians, and researchers with a dependable source of information on current treatment options and patient care.• Evidence for current treatment options for interstitial pneumonia, idiopathic pulmonary fibrosis, and smoking-related interstitial lung diseases. • Approach to diagnosis of interstitial lung diseases, such as sarcoidosis, hypersensitivity pneumonitis, and Churg-Strauss syndrome.• Genetic markers for inherited interstitial lung diseases such as dyskeratosis congenita, tuberous sclerosis/LAM, and hyper-IgE syndrome.
Book Synopsis Management of Chronic Obstructive Pulmonary Disease by : N.M. Siafakas
Download or read book Management of Chronic Obstructive Pulmonary Disease written by N.M. Siafakas and published by European Respiratory Society. This book was released on 2006-12-01 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the 1970s, therapeutic nihilism has moved towards a more optimistic attitude regarding therapeutic alternatives in COPD. Research focused on inflammatory and physiological mechanisms has substantially increased during the last 10 years. This has led to an increased understanding of the pathophysiology of the disease, which has resulted in improved treatment. Thus, in parallel to smoking-cessation programmes, other treatment modalities have been shown to be successful. Physiotherapy and pharmacotherapy have been extensively studied and the knowledge regarding what these therapeutic approa.
Book Synopsis Airway Remodeling by : Peter Howarth
Download or read book Airway Remodeling written by Peter Howarth and published by CRC Press. This book was released on 2001 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This landmark volume discusses the characteristics and impact of the remodeling process on airway function and clinical disease expression within the airway in asthma, covering pharmacological therapies and possible future targets relevant to regulating the remodeling process. Emphasizes the importance of treating underlying airway inflammation and the relevance of structural alterations to the airway wall, including glandular increases, enhanced collagen deposition within the submucosa, increased vasculature, smooth hypertrophy, and hyperplasias! Tracing the development and maintenance of bronchial hyperresponsiveness, decline in lung function, and loss of reversibility evident in chronic asthma, Airway Remodelingdescribes the contribution of inflammatory cells in the development of airway structural changes examines how pharmaceutical agents act and whether existing treatments modify or prevent remodeling in chronically inflamed asthmatic airways considers whether neural pathways initiate as well as contribute to the airway inflammatory cascade that leads to remodeling reviews the action of cytokines and growth factors on ASM signaling outlines novel approaches to regulating smooth muscle growth clarifies whether permanent ventilatory incapacity in asthma is caused by the uncoupling of the airway and the role of the lung parenchyma details high-resolution computerized tomography scan to measure the internal size of the airway at baseline, during challenge, or after bronchodilatation and more!Improving lung function and quality of life by reducing the need for emergency care, hospital admissions, and systemic steroid administration, Airway Remodeling is a superb reference for pulmonologists and respiratory system specialists; physiologists; pneumologists; allergists; pharmacologists; molecular, cellular, and lung biologists; and graduate and medical school students in these disciplines.
Book Synopsis Clinically Relevant Mycoses by : Elisabeth Presterl
Download or read book Clinically Relevant Mycoses written by Elisabeth Presterl and published by Springer. This book was released on 2018-12-17 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes an evidence-based, practical approach to diagnosis and treatment of the fungal infections most frequently encountered in a general hospital. The opening section provides an easy-to-understand overview of the basic medical and scientific background of fungal infections. Epidemiology, pathogenesis, clinical presentation, diagnostics, and treatment are then carefully explained and discussed for a variety of clinical syndromes, including those associated with Candida, Aspergillus, Cryptococcus, and Pneumocystis spp., Mucoraceae, dermatophytes, and rare fungi. Readers will gain a clear perception of common management challenges and the best way to respond to them, including in specific patient groups such as children and the immunocompromised. In addition to providing an excellent tool for decision-making on clinical management, the book offers a sound basis for the framing of further research questions and studies in the field. It will be an invaluable companion for doctors, students of medicine and pharmacology, nurses, and other health care professionals.
Book Synopsis ERS Handbook of Paediatric Respiratory Medicine by : Ernst Eber
Download or read book ERS Handbook of Paediatric Respiratory Medicine written by Ernst Eber and published by European Respiratory Society. This book was released on 2021 with total page 915 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 19 sections of this second edition of the ERS Handbook of Paediatric Respiratory Medicine cover the whole spectrum of paediatric respiratory medicine, from anatomy and development to disease, rehabilitation and treatment. The editors have brought together leading clinicians to produce a thorough and easy-to-read reference tool. The Handbook is structured to accompany the paediatric HERMES syllabus, making it an essential resource for anyone interested in this field and an ideal educational training guide.
Book Synopsis Computed Tomography of the Chest by : Stanley S. Siegelman
Download or read book Computed Tomography of the Chest written by Stanley S. Siegelman and published by . This book was released on 1984 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Idiopathic Pulmonary Fibrosis by : Ulrich Costabel
Download or read book Idiopathic Pulmonary Fibrosis written by Ulrich Costabel and published by European Respiratory Society. This book was released on 2016-03-01 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Idiopathic pulmonary fibrosis (IPF) is a steadily progressive and ultimately fatal disease of unknown origin. Recent years have seen advances in our understanding of IPF and a number of guidelines have been published. But many questions remain unanswered, particularly surrounding probable versus definite IPF. This Monograph aims to discuss the latest achievements in IPF, and covers key diagnostic issues, staging of the disease, complications and comorbidities, treatment, unmet patient needs and perspectives for the future. This book will be of interest to all clinicians and researchers in this area.
Book Synopsis Clinical Metabolomics Applications in Genetic Diseases by : Anas M. Abdel Rahman
Download or read book Clinical Metabolomics Applications in Genetic Diseases written by Anas M. Abdel Rahman and published by Springer Nature. This book was released on 2023-10-31 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book helps readers discover the forefront of personalized medicine on clinical metabolomics and its applications in genetic diseases. This comprehensive guide offers a functional relationship map between cell components and genetic variations in various diseases, providing insights that can be applied to personalized medicine. The book covers the latest developments in metabolomics for health, with practical guidance for clinical experts looking to advance their laboratory techniques and career. The metabolomics profile is a powerful tool that has revolutionized our understanding of the relationship between genetics, clinical readouts, and disease outcomes. By integrating metabolomics with genomics and clinical phenotypes, the authors have developed diagnostic and prediction models that have vastly improved patient outcomes and deepened the understanding of disease mechanisms. This model has been successfully applied in various conditions, including inborn errors of metabolism, primary immunodeficiency, and endocrine disorders. However, integrating metabolomics with other omics datasets and clinical phenotypes requires careful study design, analytical tools, and data analysis and interpretation. This groundbreaking new book provides essential guidance for researchers, students, and professionals looking to leverage metabolomics in their own work, including biochemical and clinical geneticists, pharmacogenomics and pharmacometabolomics experts, pharmaceutics and diagnostic researchers, medical scientists, clinical dietitians, metabolic engineers, clinical chemists, and personalized medicine specialists.
Book Synopsis Chronic Obstructive Pulmonary Disease Exacerbations by : Jadwiga A. Wedzicha
Download or read book Chronic Obstructive Pulmonary Disease Exacerbations written by Jadwiga A. Wedzicha and published by CRC Press. This book was released on 2008-09-22 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic Obstructive Pulmonary Disease Exacerbations covers the definition, diagnosis, epidemiology, mechanisms, and treatment associated with COPD exacerbations. This text also addresses imaging and how it plays a pivotal role in the diagnosis and study of exacerbations.Written by today's top experts, Chronic Obstructive Pulmonary Disease Exacerbat
Book Synopsis Clinical Tuberculosis by : Peter D. O. Davies
Download or read book Clinical Tuberculosis written by Peter D. O. Davies and published by CRC Press. This book was released on 2014-04-30 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely updated and revised, Clinical Tuberculosis continues to provide the TB practitioner-whether in public health, laboratory science or clinical practice-with a synoptic and definitive account of the latest methods of diagnosis, treatment and control of this challenging and debilitating disease.New in the Fifth Edition:Gamma interferon-based
