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Clinical Dilemmas In Primary Liver Cancer
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Book Synopsis Clinical Dilemmas in Primary Liver Cancer by : Roger Williams
Download or read book Clinical Dilemmas in Primary Liver Cancer written by Roger Williams and published by John Wiley & Sons. This book was released on 2011-12-27 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Dilemmas in Liver Cancer follows the successful format of the other books in the Clinical Dilemmas series, with each chapter focused on a specific dilemma, or issue facing doctors in their day-to-day job, and providing them with practical clinical information and help to better assessment and treat their patients – in this case patients suffering from liver cancer, the third commonest cancer in terms of mortality worldwide. Chapters feature up-to-date information on the basic mechanisms, epidemiological risk factors, screening and surveillance strategies, diagnosis and treatment. It is an extremely practical and clinically-orientated book, and as most patients around the world present with advanced disease, a main focus is on the most recent advances allowing early diagnosis and use of locoregional and systemic therapy, surgery, transplantation and combination therapies. Each chapter is authored by an international expert in the relevant area.
Book Synopsis Clinical Dilemmas in Primary Liver Cancer by : Roger Williams
Download or read book Clinical Dilemmas in Primary Liver Cancer written by Roger Williams and published by John Wiley & Sons. This book was released on 2011-11-03 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Dilemmas in Liver Cancer follows the successful format of the other books in the Clinical Dilemmas series, with each chapter focused on a specific dilemma, or issue facing doctors in their day-to-day job, and providing them with practical clinical information and help to better assessment and treat their patients – in this case patients suffering from liver cancer, the third commonest cancer in terms of mortality worldwide. Chapters feature up-to-date information on the basic mechanisms, epidemiological risk factors, screening and surveillance strategies, diagnosis and treatment. It is an extremely practical and clinically-orientated book, and as most patients around the world present with advanced disease, a main focus is on the most recent advances allowing early diagnosis and use of locoregional and systemic therapy, surgery, transplantation and combination therapies. Each chapter is authored by an international expert in the relevant area.
Book Synopsis Clinical Dilemmas in Viral Liver Disease by : Graham Foster
Download or read book Clinical Dilemmas in Viral Liver Disease written by Graham Foster and published by John Wiley & Sons. This book was released on 2011-09-22 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Dilemmas in Viral Liver Disease is a practicalup-to-date handbook providing answers to the questions andchallenges that arise in day-to-day practice. Each short chapter addresses a different topic and providesevidence-based guidance on subjects ranging from optimizing currentmanagement through to special management problems and noveltreatments. This book is suitable for all medical professionals involved inthe care of patients with viral liver disease: established andtrainee hepatologists, pediatric hepatologists, pathologists,radiologists, transplant surgeons and nurse specialists
Book Synopsis Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease by : Roger Williams
Download or read book Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease written by Roger Williams and published by John Wiley & Sons. This book was released on 2016-02-16 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease offers hepatologists practical, up-to-date and expert guidance on the most topical dilemmas, difficulties and areas of controversy/difficulty surrounding this ever-increasing area of liver disease they face in daily practice. Roger Williams and Simon Taylor-Robinson, two of Europe’s leading hepatologists, have recruited leading figures from across the world to assist them, resulting in a truly international approach. Each chapter covers a specific area of difficulty, containing clear learning points and providing evidence-based expert guidance on the latest hot topics in clinical management such as: Is NAFLD different in absence of Metabolic Syndrome? Are the pros outweighed by the cons of obtaining a liver biopsy? Is progression to cirrhosis more likely in children with NAFLD? What are the dangers as well as the true benefits of bariatric surgery? How is it best to use antifibrotic agents in clinical practice? Clinical Dilemmas in Non-Alcoholic Fatty Liver Disease provides the answers to the questions and challenges that clinicians face every day in this area. It is essential reading for hepatologists of all levels and researchers in hepatology, as well as all those involved in the care of patients with NAFLD, including gastroenterologists, pathologists and specialist hepatology nurses.
Book Synopsis Guidelines on Hepatitis B and C Testing by : World Health Organization
Download or read book Guidelines on Hepatitis B and C Testing written by World Health Organization and published by World Health Organization. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Testing and diagnosis of hepatitis B (HBV) and C (HCV) infection is the gateway for access to both prevention and treatment services, and is a crucial component of an effective response to the hepatitis epidemic. Early identification of persons with chronic HBV or HCV infection enables them to receive the necessary care and treatment to prevent or delay progression of liver disease. Testing also provides an opportunity to link people to interventions to reduce transmission, through counselling on risk behaviors and provision of prevention commodities (such as sterile needles and syringes) and hepatitis B vaccination. These are the first WHO guidelines on testing for chronic HBV and HCV infection and complement published guidance by WHO on the prevention, care and treatment of chronic hepatitis C and hepatitis B infection. These guidelines outline the public health approach to strengthening and expanding current testing practices for HBV and HCV, and are intended for use across age groups and populations.
Book Synopsis Hepatocellular Carcinoma by : Yujin Hoshida
Download or read book Hepatocellular Carcinoma written by Yujin Hoshida and published by Springer. This book was released on 2019-08-05 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the current limitations and unmet needs in Hepatocellular Carcinoma (HCC) diagnosis, treatment, and prevention. It also provides newly emerging concepts, approaches, and technologies to address challenges. Topics covered include changing landscape of HCC etiologies in association with health disparities, framework of clinical management algorithm, new and experimental modalities of HCC diagnosis and prognostication, multidisciplinary treatment options including rapidly evolving molecular targeted therapies and immune therapies, multi-omics molecular characterization, and clinically relevant experimental models. The book is intended to assist collaboration between the diverse disciplines and facilitate forward and reverse translation between basic and clinical research by providing a comprehensive overview of relevant areas, covering epidemiological trend and population-level patient management strategies, new diagnostic and prognostic tools, recent advances in the standard care and novel therapeutic approaches, and new concepts in pathogenesis and experimental approaches and tools, by experts and opinion leaders in their respective fields. By thoroughly and concisely covering whole aspects of HCC care, Hepatocellular Carcinoma serves as a valuable reference for multidisciplinary readers, and promotes the development of personalized precision care strategies that lead to substantial improvement of disease burden and patient prognosis in HCC.
Book Synopsis Clinical Dilemmas in Viral Liver Disease by : Graham R. Foster
Download or read book Clinical Dilemmas in Viral Liver Disease written by Graham R. Foster and published by John Wiley & Sons. This book was released on 2020-05-04 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only evidence-based book to approach viral liver disease by focusing exclusively on the clinical dilemmas encountered by hepatologists and their medical teams Although viral hepatitis is a growing public health risk around the world, the World Health Organization (WHO) views the elimination of hepatitis infection over the next several as an achievable goal. Effective pharmaceutical therapies are now available, yet medical teams caring for patients with viral hepatitis are challenged when looking for answers to specific questions in the current medical literature. The second edition of Clinical Dilemmas in Viral Liver Disease provides evidence-based guidance for medical teams involved in diagnosing, treating, and managing patients with viral liver disease. This fully updated book explores developments in new treatments and new diagnostic approaches that are contributing to WHO goals of viral elimination. Brief, easily referenced chapters examine clearly defined topics, addressing the clinical questions and difficulties encountered by medical teams in day-to-day practice. Contributions by an international team of investigators and clinicians address clinical questions and issues which are seldom found in standard textbooks and online repositories. Offering practical guidance on the specific challenges and dilemmas of treating viral liver disease, this unique volume: Provides practical, evidence-based guidance on topical and controversial issues Addresses understudied questions that arise in day-to-day clinical practice Discusses the challenges surrounding global elimination programs Presents focused approach that is supported by current literature and expert opinion The second edition of Clinical Dilemmas in Viral Liver Disease is required reading for practicing and trainee hepatologists, gastroenterologists, transplant surgeons, virologists, and other practitioners involved in caring for patients with liver disease.
Book Synopsis Chronic Liver Failure by : Pere Ginès
Download or read book Chronic Liver Failure written by Pere Ginès and published by Springer Science & Business Media. This book was released on 2010-11-03 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.
Book Synopsis Stereotactic Body Radiation Therapy by : Simon S. Lo
Download or read book Stereotactic Body Radiation Therapy written by Simon S. Lo and published by Springer Science & Business Media. This book was released on 2012-08-28 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.
Book Synopsis Hepato-Pancreato-Biliary and Transplant Surgery by : Quyen D Chu
Download or read book Hepato-Pancreato-Biliary and Transplant Surgery written by Quyen D Chu and published by Beaux Books Publishing, LLC. This book was released on 2018-01-08 with total page 1352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique textbook provides a concise and practical approach to clinical dilemmas involving the liver, pancreas, and biliary tree. Six major sections encompass (1) Hepatic, (2) Biliary, (3) Pancreas, (4) Transplantation, (5) Trauma, and (6) Innovative Technology. Each topic is written by recognized experts from an "e;experiential"e; viewpoint combined with evidence-based medicine. The book contains over 170 chapters and over 350 contributors. It is relevant to Surgical Oncologists, Hepato-Pancreato-Biliary (HPB) Surgeons, Transplant Surgeons, Traumatologists, HPB Interventionalists, General Surgeons, and trainees and students. The title of each chapter is in a form of a clinical scenario and each chapter begins with a Case Scenario and ends with Salient Points. Special debates are included in each section. There are numerous compelling images, detailed illustrations, comprehensive tables, thorough algorithms, and other adjunctive tools that enhance learning. The authors emanate from different corners of the world. The book is a valuable resource for faculty, students, surgical trainees, fellows, and all health care providers in the HPB/Trauma/Transplant/Oncology fields.
Book Synopsis Hepatocellular Carcinoma in Sub-Saharan Africa by : Michael Charles Kew
Download or read book Hepatocellular Carcinoma in Sub-Saharan Africa written by Michael Charles Kew and published by . This book was released on 2012-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book comprehensively covers all aspects of hepatocellular carcinoma (cancer) as it occurs in sub-Saharan black Africans and how the cancer differs from that in other parts of the world, in most of which it occurs infrequently. The first chapter is introduced with a discussion of the difficulty in recording all cases of this cancer in sub Saharan Africa and then covers its epidemiology, emphasising the very high incidence of liver cancer in sub Saharan black Africans. The relatively young age at which the tumor occurs in comparison with the older age of the patients in resource-rich regions is stressed. The sex distribution of the cancer is also discussed. The second chapter describes the ways in which hepatocellular cancer presents in black Africans, its symptoms and signs, and how its presentation differs from that in other parts of the world. The third chapter summarises the grave outlook for patients with the tumor, the very short survival times of the patients, and the reasons for their deaths. The fourth chapter discusses the diagnosis of the cancer and why this is far more difficult than it is in resource-rich countries. The fifth chapter deals with the pathology of the tumor-its similarities and differences from that in other parts of the world. The sixth chapter is the longest in the book, and it deals comprehensively with the causes of liver cancer in sub-Saharan Africa. The major cause is chronic infection with the hepatitis B virus, an infection acquired in early childhood, and the possible mechanisms by which this may cause the cancer. Other less common but still important causes in the subcontinent-such as exposure to the fungal carcinogen, aflatoxin, chronic hepatitis C virus infection, dietary iron overload among Africans, and membranous obstruction of the inferior vena cava-are also discussed. The seventh chapter discusses the difficulty in treating hepatocellular cancer and the poor results obtained in sub-Saharan Africa in comparison with the results of treatment in industrialized countries. The penultimate chapter presents possible ways to prevent the cancer or, at least, to detect it at a far earlier time than is currently the case and when it may be more amenable to treatment. The current status of vaccination in preventing hepatitis B virus infection, and hence liver cancer, is discussed in detail. The final chapter asks the question, "How can we improve the diagnosis and treatment of this dreadful malignant disease?"
Book Synopsis Targeted Therapies in Oncology, Second Edition by : Giuseppe Giaccone
Download or read book Targeted Therapies in Oncology, Second Edition written by Giuseppe Giaccone and published by CRC Press. This book was released on 2013-10-21 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the last edition of this book, major advances have been made in our understanding of key pathways that control tumor progression. This has led to the development of new anticancer agents that have the ability to block the activity of proteins involved in neoplastic cell development and proliferation. Targeted Therapies in Oncology, Second Edition provides a concise timely panorama of existing targeted therapies and progress into future anticancer treatments. These therapies notably include: Targeted agents of immune checkpoints Signal-transduction inhibitors Antiangiogenic agents Vascular-disrupting agents Apoptosis modulators Stem cell inhibitors Tumor profiling for drug development The book emphasizes the biology behind this new class of drugs as well as the clinical achievements obtained. The contributors to this volume stand at the cutting edge of cancer research and treatment around the world.
Download or read book Drug-Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series
Book Synopsis Perioperative Chemotherapy by : U. Metzger
Download or read book Perioperative Chemotherapy written by U. Metzger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.
Book Synopsis Imaging in Clinical Oncology by : Athanasios D. Gouliamos
Download or read book Imaging in Clinical Oncology written by Athanasios D. Gouliamos and published by Springer. This book was released on 2018-10-04 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second edition of a well-received book reflecting the state of the art in oncologic imaging research and promoting mutual understanding and collaboration between radiologists and clinical oncologists. It presents all currently available imaging modalities and covers a broad spectrum of oncologic diseases for most organ systems. Today, oncologic imaging faces the challenge of improving and refining concepts for precise tumor delineation and biologic/functional tumor characterization, as well as for purposes of creating individual treatment plans. The concept of radiomics has further advanced the conversion of images into mineable data and subsequent analysis of said data for decision-making support. Since the release of the book’s first edition, radiomics has been introduced in oncology studies and can be performed with tomographic images from CT, MRI and PET/CT studies. The combination of radiomic data with genomic features is known as radiogenomics, and can potentially offer additional decision-making support. This book will be of interest to clinical oncologists with regard to the diagnosis, staging, treatment and follow-up on various tumors affecting the CNS, chest, abdomen, urogenital and musculoskeletal systems.
Book Synopsis Hepatobiliary Cancer by : Paul H. Sugarbaker
Download or read book Hepatobiliary Cancer written by Paul H. Sugarbaker and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: When one deals with cancer, the hepatobiliary malignancies present a chal lenge to the oncologists that can be characterized as a series of unsolved clinical and biological dilemmas. Liver metastases from colorectal and other gastrointestinal malignancies, hepatocellular carcinoma, cholangiocar cinoma, and gall bladder cancer present an array of problems but have two features in common. These are high morbidity and mortality with an overall poor result from treatment. Why is it that hepatobiliary cancer carries with it such a dismal prognosis? First of all, these diseases present, for the most part, in an advanced state. To this point in time the oncologist has had no help from early diagnosis or screening. Only the occasional patient followed by ultrasound or a tumor marker has the disease diagnosed in an asymptomatic state. By the time these diseases become symptomatic, curative treatment options have usually disappeared. Evolution has placed the liver in a protected position in order to avoid injury to the soft parenchyma. As with many other internal organs, the nerve supply is extremely limited. These two anatomic features result in a great lack of early warning signs of cancer.
Book Synopsis Surgical Pathology of Liver Tumors by : Taofic Mounajjed
Download or read book Surgical Pathology of Liver Tumors written by Taofic Mounajjed and published by Springer. This book was released on 2015-07-21 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a practical guide for the diagnostic surgical pathologist in evaluating tumors involving the liver. It comprehensively covers the histological findings and key clinical and molecular correlates of liver tumors. The focus is on material that is most relevant to the actual practice of liver pathology including those aspects that are directly relevant to the diagnosis, subtyping and prognostication of hepatic adenomas specimens, including biopsy specimens and surgical resections. The book will teach pathologists how to avoid common diagnostic pitfalls. Each chapter uses or discusses the nomenclature and classification system of liver tumors as per the current WHO classification of liver tumors. Each chapter fully incorporates the most up to date diagnostic methodologies, including immunohistochemistry and molecular methods. Referencing is succinct and references were carefully chosen for their key role as the primary sources of information on a given disease. The text is richly illustrated with beautiful color images that highlight not just the “average” histological findings for a given entity, but also fully illustrate all of the key histological variability. Gross images are also included to highlight important diagnostic features. Tables are used judiciously to present summary information that allows a quick review on how similar entities compare and contrast. In addition, the clinical significance of various diseases will be discussed in a focused fashion that highlights how pathology information is being used to make key clinical management decisions. Each chapter is written by experts in hepatopathology, all from the Mayo Clinic Departments of Pathology. Surgical Pathology of Liver Tumors will be of great utility to surgical pathologists and surgical pathologists in training as well as clinicians involved in the care of patients with liver tumors, particularly hepatologists and oncologists.
