Clinical Applications Of Immunomics

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Clinical Applications of Immunomics

Author : Andras Falus
Publisher : Springer Science & Business Media
ISBN 13 : 0387792082
Total Pages : 284 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Clinical Applications of Immunomics by : Andras Falus

Download or read book Clinical Applications of Immunomics written by Andras Falus and published by Springer Science & Business Media. This book was released on 2008-12-23 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Innate immunity is one the most evolutionally conserved systems, designed to protect the organism from viruses and bacterial infections, stress and many other types of attacks from the outside world. During the past decade, the capacity of molecular biology and information technology to produce and analyse data have grown exponentially, rapidly reforming many aspects of immunology research in the post-genomics era. As a result, scientific understanding of signalling networks governing the innate immunity response in human tissues and other organisms has evolved beyond recognition, compared to even just a decade ago. Many strategies have been designed over the years to identify novel proteins, which have a crucial role in innate immunity responses by regulating particular signalling pathways. These projects had many advantages, including the definition of novel drug targets, as exemplified by the recent success of anti-TNF therapy, as well as leading to a better, system-wide understanding of the molecular control of innate immunity. In the past few years, a new concept, Immunomics, has been adopted to define an emerging, multidisciplinary field of research (Schonbach, 2003). Although rapid progress has been made to identify the proteins playing pivotal roles in the innate immunity–related signalling pathways (for example, TIR signalling pathways), the catalogue of proteins with a key regulatory function identified and studied is far from completed. Novel proteins need to be char- terised to gain a more comprehensive picture of how signalling networks are regulated.

Computational Immunology

Author : Josep Bassaganya-Riera
Publisher : Academic Press
ISBN 13 : 0128037156
Total Pages : 212 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Computational Immunology by : Josep Bassaganya-Riera

Download or read book Computational Immunology written by Josep Bassaganya-Riera and published by Academic Press. This book was released on 2015-10-21 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Immunology: Models and Tools encompasses the methodological framework and application of cutting-edge tools and techniques to study immunological processes at a systems level, along with the concept of multi-scale modeling. The book's emphasis is on selected cases studies and application of the most updated technologies in computational modeling, discussing topics such as computational modeling and its usage in immunological research, bioinformatics infrastructure, ODE based modeling, agent based modeling, and high performance computing, data analytics, and multiscale modeling. There are also modeling exercises using recent tools and models which lead the readers to a thorough comprehension and applicability. The book is a valuable resource for immunologists, computational biologists, bioinformaticians, biotechnologists, and computer scientists, as well as all those who wish to broaden their knowledge in systems modeling. - Offers case studies with different levels of complexity - Provides a detailed view on cutting-edge tools for modeling that are useful to experimentalists with limited computational skills - Explores the usage of simulation for hypothesis generation, helping the reader to understand the most valuable points on experimental setting

Chemical Genomics and Proteomics

Author : Ferenc Darvas
Publisher : CRC Press
ISBN 13 : 1439830592
Total Pages : 235 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Chemical Genomics and Proteomics by : Ferenc Darvas

Download or read book Chemical Genomics and Proteomics written by Ferenc Darvas and published by CRC Press. This book was released on 2013-01-11 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the pioneering first edition of Chemical Genomics and Proteomics more than seven years ago, the area of chemical genomics has rapidly expanded and diversified to numerous novel methods and subdisciplines, such as chemical glycomics and lipidomics. This second edition has been updated to uniquely reflect this interdisciplina

Immunoinformatics

Author : Namrata Tomar
Publisher : Humana
ISBN 13 : 9781071603918
Total Pages : 409 pages
Book Rating : 4.6/5 (39 download)

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Book Synopsis Immunoinformatics by : Namrata Tomar

Download or read book Immunoinformatics written by Namrata Tomar and published by Humana. This book was released on 2021-03-26 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers a wide range of diverse immunoinformatics research topics, involving tools and databases of potential epitope prediction, HLA gene analysis, MHC characterizing, in silico vaccine design, mathematical modeling of host-pathogen interactions, and network analysis of immune system data. In that way, this fully updated volume explores the enormous value of computational tools and models in immunology research. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of key insights and detailed implementation advice to encourage successful results in the lab. Authoritative and practical, Immunoinformatics, Third Edition serves as an ideal guide for scientists working at the intersection of bioinformatics, mathematical modelling, and statistics for the study of immune systems biology.

Immunoinformatics

Author : Christian Schönbach
Publisher : Springer Science & Business Media
ISBN 13 : 0387729682
Total Pages : 216 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Immunoinformatics by : Christian Schönbach

Download or read book Immunoinformatics written by Christian Schönbach and published by Springer Science & Business Media. This book was released on 2007-11-21 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: In contrast to existing books on immunoinformatics, this volume presents a cross-section of immunoinformatics research. The contributions highlight the interdisciplinary nature of the field and how collaborative efforts among bioinformaticians and bench scientists result in innovative strategies for understanding the immune system. Immunoinformatics is ideal for scientists and students in immunology, bioinformatics, microbiology, and many other disciplines.

The Silent Cry: How to Turn Translational Medicine Towards Patients and Unmet Medical Needs

Author : Manuela Battaglia
Publisher : Frontiers Media SA
ISBN 13 : 2889636798
Total Pages : 150 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis The Silent Cry: How to Turn Translational Medicine Towards Patients and Unmet Medical Needs by : Manuela Battaglia

Download or read book The Silent Cry: How to Turn Translational Medicine Towards Patients and Unmet Medical Needs written by Manuela Battaglia and published by Frontiers Media SA. This book was released on 2020-05-12 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Science and Applications of Synthetic and Systems Biology

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309219396
Total Pages : 570 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis The Science and Applications of Synthetic and Systems Biology by : Institute of Medicine

Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines

Author : Darren R. Flower
Publisher : Springer Science & Business Media
ISBN 13 : 1461450705
Total Pages : 316 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines by : Darren R. Flower

Download or read book Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines written by Darren R. Flower and published by Springer Science & Business Media. This book was released on 2012-12-09 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will address an important emergent area within the field of immunomics: the discovery of antigens and adjuvants within the context of reverse vaccinology. Conventional approaches to vaccine design and development requires pathogens to be cultivated in the laboratory and the immunogenic molecules within them to be identifiable. Conventional vaccinology is no longer universally successful, particularly for recalcitrant pathogens. By using genomic information we can study vaccine development in silico: 'reverse vaccinology', can identify candidate subunits vaccines by identifying antigenic proteins and by using equally rational approaches to identify novel immune response-enhancing adjuvants.

Bioreactor Design Concepts for Viral Vaccine Production

Author : Surajbhan Sevda
Publisher : Elsevier
ISBN 13 : 0443153795
Total Pages : 476 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Bioreactor Design Concepts for Viral Vaccine Production by : Surajbhan Sevda

Download or read book Bioreactor Design Concepts for Viral Vaccine Production written by Surajbhan Sevda and published by Elsevier. This book was released on 2024-05-12 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioreactor Design Concepts for Viral Vaccine Production covers a range of interdisciplinary chapters from the engineering perspective of bioreactor design to the biotechnological perspectives of vector design for vaccine development. The book covers bioreactor concepts such as static systems, single-use systems, stirred tanks, perfusion, wave and packed-beds. It reviews options for efficient and economical production of human vaccines and discusses basic factors relevant for viral antigen production in mammalian cells, avian cells, and insect cells. This book will be a great resource for those interested in implemented novel bioreactor design or experimental schemes towards intensified or/and enhanced vaccine production. - Covers the fundamentals of bioreactor designs - Provides strategies for designing a successful vector-based vaccine - Discusses the applications of biological kinetics, thermodynamics and basic substrate requirements for viral vaccine production

Basic Immunology and Its Clinical Application

Author : Mitsuru Matsumoto
Publisher : Springer Nature
ISBN 13 : 981999781X
Total Pages : 252 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Basic Immunology and Its Clinical Application by : Mitsuru Matsumoto

Download or read book Basic Immunology and Its Clinical Application written by Mitsuru Matsumoto and published by Springer Nature. This book was released on with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunoinformatics

Author : Gregory R. Bock
Publisher : John Wiley & Sons
ISBN 13 : 0470090758
Total Pages : 272 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Immunoinformatics by : Gregory R. Bock

Download or read book Immunoinformatics written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2004-03-05 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The astounding diversity of the immune system and the complexity of its regulatory pathways makes immunology a combinatorial science. Computational analysis has therefore become an essential element of immunology research and this has led to the creation of the emerging field of immunoinformatics. This book is the first to feature thorough coverage of this new field. Immunoinformatics facilitates the understanding of immune function by modelling the interactions among immunological components. Biological research provides ever deeper insights into the complexity of living organisms while computer science provides an effective means to store and analyse large volumes of complex data. Combining the two fields increases the efficiency of biological research and offers the potential for major advances in the study of biological systems. This book encompasses key developments in immunoinformatics, including immunological databases, sequence analysis, structure modelling, mathematical modelling of the immune system, simulation of laboratory experiments, statistical support for immunological experimentation and immunogenomics. The difficulties in effective application of bioinformatic tools in immunology arise at both ends of the spectrum: most immunologists have only a limited comprehension of sophisticated data analysis and applicability and limitations, while the average computer scientist lacks knowledge of the depth and complexity of biological data. The purpose of this book, therefore, is to present contributions from a multidisciplinary team of biologists and computer scientists to explore the issues related to better understanding of immune function and, in particular, to help apply new computer science methods to immunological research. Related Novartis Foundation symposia: 247 In Silico Simulation of Biological Processes Chair: Denis Noble 252 Generation and effector functions of regulatory lymphocytes Chair: Jean-François Bach

Microbial Products

Author : Mamtesh Singh
Publisher : CRC Press
ISBN 13 : 1000626679
Total Pages : 798 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Microbial Products by : Mamtesh Singh

Download or read book Microbial Products written by Mamtesh Singh and published by CRC Press. This book was released on 2022-11-16 with total page 798 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Products: Applications and Translational Trends offers complete coverage of the production of microbial products, including biopolymers, biofuels, bioactive compounds, and their applications in fields such as bioremediation, agriculture, medicine, and other industrial settings. This book focuses on multiple processes including upstream procedures and downstream processing, and the tools required for their production. Lab-scale development processes may not be as efficient when aiming for large-scale industrial production, so it is necessary to utilize in silico modeling tools for bioprocess design to ensure success at translational levels. Therefore, this book presents in silico and mathematical simulations and approaches used for such applications. Further, it examines microbial products produced from bacteria, fungi, and algae. These major microbial categories have the capacity to produce various, diverse secondary metabolites, bioactive compounds, enzymes, biopolymers, biofuels, probiotics, and more. The bioproducts examined in the book are of great social, medical, and agricultural benefit, and include examples of biodegradable polymers, biofuels, biofertilizers, and drug delivery agents. Presents approaches and tools that aid in the design of eco-friendly, efficient, and economic bioprocesses. Utilizes in silico and mathematical simulations for optimal bioprocess design. Examines approaches to be used for bioproducts from the lab scale to widely applied microbial biotechnologies. Presents the latest trends and technologies in the production approaches for microbial bio-products manufacture and application. This book is ideal for both researchers and academics, as it provides up-to-date knowledge of applied microbial biotechnology approaches for bio-products.

Reverse Vaccinology

Author : Pedro A Reche
Publisher : Frontiers Media SA
ISBN 13 : 2889633853
Total Pages : 139 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Reverse Vaccinology by : Pedro A Reche

Download or read book Reverse Vaccinology written by Pedro A Reche and published by Frontiers Media SA. This book was released on 2020-01-15 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Acute Rheumatic Fever and Rheumatic Heart Disease

Author : Dr. Scott Dougherty
Publisher : Elsevier Health Sciences
ISBN 13 : 0323754600
Total Pages : 364 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Acute Rheumatic Fever and Rheumatic Heart Disease by : Dr. Scott Dougherty

Download or read book Acute Rheumatic Fever and Rheumatic Heart Disease written by Dr. Scott Dougherty and published by Elsevier Health Sciences. This book was released on 2020-02-22 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute Rheumatic Fever and Rheumatic Heart Disease is a concise, yet comprehensive, clinical resource highlighting must-know information on rheumatic heart disease and acute rheumatic fever from a global perspective. Covering the major issues dominating the field, this practical resource presents sufficient detail for a deep and thorough understanding of the latest treatment options, potential complications, and disease management strategies to improve patient outcomes. - Divided into four distinct sections for ease of navigation: Acute Rheumatic Fever, Rheumatic Heart Disease, Population-Based Strategies for Disease Control, and Acute and Emergency Presentations. - International editors and chapter authors ensure a truly global perspective. - Covers all clinical aspects, including epidemiology, pathophysiology, clinical features, diagnosis, management, and treatment. - Includes key topics on population-based measures for disease control for effective primary, secondary, and tertiary prevention. - Consolidates today's available information and guidance into a single, convenient resource.

Oncogene Proteins

Author : Peter B. Murphy
Publisher : Nova Publishers
ISBN 13 : 9781604562590
Total Pages : 368 pages
Book Rating : 4.5/5 (625 download)

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Book Synopsis Oncogene Proteins by : Peter B. Murphy

Download or read book Oncogene Proteins written by Peter B. Murphy and published by Nova Publishers. This book was released on 2008 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oncogene proteins are proteins coded by oncogenes. They include proteins resulting from the fusion of an oncogene and another gene. This new book presents the latest research in the field from around the world.

Encyclopedia of Bioinformatics and Computational Biology

Author :
Publisher : Elsevier
ISBN 13 : 0128114320
Total Pages : 3421 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Encyclopedia of Bioinformatics and Computational Biology by :

Download or read book Encyclopedia of Bioinformatics and Computational Biology written by and published by Elsevier. This book was released on 2018-08-21 with total page 3421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Post-genomic Approaches in Drug and Vaccine Development

Author : Kishore R. Sakharkar
Publisher : CRC Press
ISBN 13 : 1000795713
Total Pages : 451 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Post-genomic Approaches in Drug and Vaccine Development by : Kishore R. Sakharkar

Download or read book Post-genomic Approaches in Drug and Vaccine Development written by Kishore R. Sakharkar and published by CRC Press. This book was released on 2022-09-01 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, genome sequencing projects and the associated efforts have facilitated the discovery of several novel disease targets and the approval of several innovative drugs. To further exploit this data for human health and disease, there is a need to understand the genome data itself in detail, discover novel targets, understand their role in physiological pathways and associated diseases, with the aim to translate these discoveries to clinical and preventive medicine. It is equally important to understand the labors and limitations in integrating clinical phenotypes with genomic, transcriptomic, proteomic and metabolomic approaches. T