The Health Effects of Cannabis and Cannabinoids

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Publisher : National Academies Press
ISBN 13 : 0309453070
Total Pages : 487 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis The Health Effects of Cannabis and Cannabinoids by : National Academies of Sciences, Engineering, and Medicine

Download or read book The Health Effects of Cannabis and Cannabinoids written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-03-31 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

Clinical Applications for Cannabis & Cannabinoids

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Publisher :
ISBN 13 : 9781737990208
Total Pages : 98 pages
Book Rating : 4.9/5 (92 download)

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Book Synopsis Clinical Applications for Cannabis & Cannabinoids by : Paul Armentano

Download or read book Clinical Applications for Cannabis & Cannabinoids written by Paul Armentano and published by . This book was released on 2021-11 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Therapeutic Uses of Cannabis

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Publisher : CRC Press
ISBN 13 : 9789057023187
Total Pages : 164 pages
Book Rating : 4.0/5 (231 download)

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Book Synopsis Therapeutic Uses of Cannabis by : British Medical Association

Download or read book Therapeutic Uses of Cannabis written by British Medical Association and published by CRC Press. This book was released on 1997-11-18 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the last Annual Representative Meeting of the British Medical Association a motion was passed that `certain additional cannabinoids should be legalized for wider medicinal use.'' This report supports this landmark statement by reviewing the scientific evidence for the therapeutic use of cannabinoids and sets the agenda for change. It will be welcomed by those who believe that cannabinoids can be used in medical treatment. The report discusses in a clear and readable form the use and adverse effects of the drug for nausea, multiple sclerosis, pain, epilepsy, glaucoma, and asthma.

Marijuana As Medicine?

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Publisher : National Academies Press
ISBN 13 : 0309065313
Total Pages : 216 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Marijuana As Medicine? by : Institute of Medicine

Download or read book Marijuana As Medicine? written by Institute of Medicine and published by National Academies Press. This book was released on 2000-12-30 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some people suffer from chronic, debilitating disorders for which no conventional treatment brings relief. Can marijuana ease their symptoms? Would it be breaking the law to turn to marijuana as a medication? There are few sources of objective, scientifically sound advice for people in this situation. Most books about marijuana and medicine attempt to promote the views of advocates or opponents. To fill the gap between these extremes, authors Alison Mack and Janet Joy have extracted critical findings from a recent Institute of Medicine study on this important issue, interpreting them for a general audience. Marijuana As Medicine? provides patientsâ€"as well as the people who care for themâ€"with a foundation for making decisions about their own health care. This empowering volume examines several key points, including: Whether marijuana can relieve a variety of symptoms, including pain, muscle spasticity, nausea, and appetite loss. The dangers of smoking marijuana, as well as the effects of its active chemical components on the immune system and on psychological health. The potential use of marijuana-based medications on symptoms of AIDS, cancer, multiple sclerosis, and several other specific disorders, in comparison with existing treatments. Marijuana As Medicine? introduces readers to the active compounds in marijuana. These include the principal ingredient in Marinol, a legal medication. The authors also discuss the prospects for developing other drugs derived from marijuana's active ingredients. In addition to providing an up-to-date review of the science behind the medical marijuana debate, Mack and Joy also answer common questions about the legal status of marijuana, explaining the conflict between state and federal law regarding its medical use. Intended primarily as an aid to patients and caregivers, this book objectively presents critical information so that it can be used to make responsible health care decisions. Marijuana As Medicine? will also be a valuable resource for policymakers, health care providers, patient counselors, medical faculty and studentsâ€"in short, anyone who wants to learn more about this important issue.

Marijuana and Medicine

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Author :
Publisher : National Academies Press
ISBN 13 : 0309071550
Total Pages : 288 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Marijuana and Medicine by : Institute of Medicine

Download or read book Marijuana and Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 1999-07-10 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The medical use of marijuana is surrounded by a cloud of social, political, and religious controversy, which obscures the facts that should be considered in the debate. This book summarizes what we know about marijuana from evidence-based medicineâ€"the harm it may do and the relief it may bring to patients. The book helps the reader understand not only what science has to say about medical marijuana but also the logic behind the scientific conclusions. Marijuana and Medicine addresses the science base and the therapeutic effects of marijuana use for medical conditions such as glaucoma and multiple sclerosis. It covers marijuana's mechanism of action, acute and chronic effects on health and behavior, potential adverse effects, efficacy of different delivery systems, analysis of the data about marijuana as a gateway drug, and the prospects for developing cannabinoid drugs. The book evaluates how well marijuana meets accepted standards for medicine and considers the conclusions of other blue-ribbon panels. Full of useful facts, this volume will be important to anyone interested in informed debate about the medical use of marijuana: advocates and opponents as well as policymakers, regulators, and health care providers.

Cannabis and Cannabinoids

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Publisher : Routledge
ISBN 13 : 1136614931
Total Pages : 482 pages
Book Rating : 4.1/5 (366 download)

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Book Synopsis Cannabis and Cannabinoids by : Ethan B Russo

Download or read book Cannabis and Cannabinoids written by Ethan B Russo and published by Routledge. This book was released on 2013-09-05 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Study the latest research findings by international experts! This comprehensive volume presents state-of-the-art scientific research on the therapeutic uses of cannabis and its derivatives. All too often, discussions of the potential medical uses of this substance are distorted by political considerations that have no place in a medical debate. Cannabis and Cannabinoids: Pharmacology, Toxicology, and Therapeutic Potential features fair, equitable discussion of this emerging and controversial medical topic by the world’s foremost researchers. Cannabis and Cannabinoids examines the benefits, drawbacks, and side effects of medical marijuana as a treatment for various conditions and diseases. This book discusses the scientific basis for marijuana’s use in cases of pain, nausea, anorexia, and cachexia. It also explores its possible benefits in glaucoma, ischemia, spastic disorders, and migraine. Cannabis and Cannabinoids examines all facets of the medical use of marijuana, including: botany history biochemistry pharmacology clinical use toxicology side effects Cannabis and Cannabinoids is a reference work that will become indispensable to physicians, psychologists, researchers, biochemists, graduate students, and interested members of the public. No other book available offers this comprehensive, even-handed look at a deeply divisive subject.

Medicinal Cannabis and CBD in Mental Healthcare

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Publisher : Springer Nature
ISBN 13 : 3030785599
Total Pages : 591 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Medicinal Cannabis and CBD in Mental Healthcare by : Kylie O'Brien

Download or read book Medicinal Cannabis and CBD in Mental Healthcare written by Kylie O'Brien and published by Springer Nature. This book was released on 2021-10-27 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book functions as a clinician’s guide to the use of cannabidiol (CBD) in the treatment of mental health conditions. It conveys the scientific evidence of efficacy of CBD as well as THC and addresses the social stigma attached to its medical use. The book describes the endocannabinoid system, how stress and the endocannabinoid system interact and key constituents, pharmacokinetics and safety aspects of medicinal cannabis, focusing on CBD and THC. Chapters on specific mental health conditions describe the underpinning pathomechanisms including how the endocannabinoid system is involved, and summarises the scientific evidence including animal and human research for the use of CBD and THC in treatment of such conditions. Topics covered include anxiety, depression, post-traumatic stress disorder, insomnia, Alzheimer's Disease and autism spectrum disorder. Chapters also discuss treatment guidelines and case studies. Unique and focused, Medicinal Cannabis and CBD in Mental Healthcare is an invaluable reference for medical practitioners seeking to adopt CBD-use in their treatment plans.

Handbook of Cannabis for Clinicians: Principles and Practice

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Publisher : W. W. Norton & Company
ISBN 13 : 0393714195
Total Pages : 438 pages
Book Rating : 4.3/5 (937 download)

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Book Synopsis Handbook of Cannabis for Clinicians: Principles and Practice by : Dustin Sulak DO

Download or read book Handbook of Cannabis for Clinicians: Principles and Practice written by Dustin Sulak DO and published by W. W. Norton & Company. This book was released on 2021-06-29 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first foundational text on the clinical use of cannabis and cannabinoid therapies. Despite thousands of years of medical use and an impressive record of safety, versatility, and efficacy, Cannabis sativa has existed outside the modern pharmacopeia since the 1940s. Primarily driven by popular demand, this botanical has returned to health care, but most clinicians lack the knowledge essential for identifying candidates for treatment, guiding patients, maximizing benefit, and minimizing harm. Dustin Sulak provides health care professionals—including physicians, psychologists, pharmacists, and nurses—with an accessible and evidence-based reference that empowers them to intelligently discuss cannabis with their patients and implement cannabis and cannabinoid therapies with confidence. Based on over a decade of clinical experience and an extensive review of the literature, this detailed and scientifically accurate guide includes the history of cannabis in medicine, the foundations of endocannabinoid physiology, the pharmacological effects of cannabis’ myriad active constituents, the clinical utility of its various preparations, and specific strategies and cautions for treating the most common conditions presenting to a cannabis clinician. This guide is an essential resource for practitioners of any specialty field or experience level who wish to improve their patients’ outcomes, harness the healing potential of the endocannabinoid system, and wield a powerful solution to many of healthcare’s challenges.

Cannabis Is Medicine

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Publisher : Little, Brown Spark
ISBN 13 : 031650081X
Total Pages : 369 pages
Book Rating : 4.3/5 (165 download)

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Book Synopsis Cannabis Is Medicine by : Bonni Goldstein

Download or read book Cannabis Is Medicine written by Bonni Goldstein and published by Little, Brown Spark. This book was released on 2020-09-29 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unlock the healing power of cannabis medicine and discover the cutting-edge science behind its remarkable impact on human health. Millions of people around the world are healing illnesses with cannabis. Nonetheless, many physicians remain reluctant to discuss cannabis medicine with their patients. And with so much conflicting misinformation from unreliable sources, finding out if cannabis could be an effective treatment for you or a loved one can feel nearly impossible. This book is the comprehensive resource for people who have not found relief from conventional medicines. Bonni Goldstein, MD, has helped thousands of patients suffering from chronic, difficult-to-treat conditions improve with cannabis. In this revelatory book, she explains the current state of scientific research on how cannabis interacts with human physiology to create homeostasis -- balance -- leading to good health. Many of the plant's compounds, including CBD and CBG, and their therapeutic effects are explained in detail. Readers will learn how to best navigate the multitude of available cannabis-based products, with detailed guidance on safety and usage, and how to customize a personalized cannabis regimen. And Dr. Goldstein presents 28 common conditions for which patients have found cannabis treatment to be effective, including cancer, insomnia and gastrointestinal disorders. As medical cannabis laws continue to evolve, it is more vital than ever for struggling patients to understand the benefits of this plant from an honest, medicine-based perspective. Educational, practical, and thorough, Cannabis Is Medicine empowers patients to make informed decisions about this natural medicine and improve the quality of their lives.

Marijuana Medical Handbook

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Author :
Publisher : Ed Rosenthal
ISBN 13 : 0932551866
Total Pages : 266 pages
Book Rating : 4.9/5 (325 download)

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Book Synopsis Marijuana Medical Handbook by : Dale Gieringer

Download or read book Marijuana Medical Handbook written by Dale Gieringer and published by Ed Rosenthal. This book was released on 2008 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: An estimated 40 million Americans have medical symptoms that marijuana can relieve. THE MARIJUANA MEDICAL HANDBOOK is a one-stop resource that gives candid, objective advice on using marijuana for healing, understanding its effects on the body, safe administration, targeting illnesses, side effects and the various delivery methods from edibles and tinctures to smokeless vapouriser pipes. This thouroughly revised edition incorporates the most up-to-date information on the ever-changing politics of marijuana, the plant's usage and medical research.

Cannabis in Medical Practice

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Publisher : McFarland
ISBN 13 : 0786483903
Total Pages : 252 pages
Book Rating : 4.7/5 (864 download)

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Book Synopsis Cannabis in Medical Practice by : Mary Lynn Mathre, R.N.

Download or read book Cannabis in Medical Practice written by Mary Lynn Mathre, R.N. and published by McFarland. This book was released on 2010-07-27 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because marijuana is a Schedule I drug under the Controlled Substances Act, the therapeutic benefits of cannabis are no longer mentioned in the formal education of health care professionals. Doctors who do learn of the drug's therapeutic value are often intimidated by its illegal status. Thus millions of patients afflicted with such illnesses as glaucoma, AIDS, cancer, multiple sclerosis, spinal cord injuries, seizure disorders and chronic pain are denied access to information about the drug's benefits and, in many cases, suffer needlessly. Straightforward and nonpoliticized information on the therapeutic uses of cannabis is provided here by medical, legal and scientific professionals. Legal issues, a worldwide history of therapeutic cannabis and a discussion of its pharmacology are covered. Specific medical uses are then examined, including its application for sufferers of cancer, AIDS, glaucoma, and seizure disorders, and its potential use in psychiatry. Dosages and administration of cannabis are explored, along with considerations on the use of the drug during pregnancy and the risks of addiction and dependency.

Cannabinoids and Sleep

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Publisher : Springer
ISBN 13 : 9783030616656
Total Pages : 183 pages
Book Rating : 4.6/5 (166 download)

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Book Synopsis Cannabinoids and Sleep by : Jaime M. Monti

Download or read book Cannabinoids and Sleep written by Jaime M. Monti and published by Springer. This book was released on 2022-02-18 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on cannabis and sleep is emerging with promising results. This book offers current and comprehensive knowledge on cannabinoid research results in connection with sleep. The volume covers aspects of the hemp plant Cannabis sativa, the pharmacology of cannabinoids, neurobiology and pharmacology of sleep and wakefulness, and the benefits and side effects of cannabis on the central nervous system. It further discusses the putative therapeutical properties of cannabinoids and endocannabinoids and their potential for the treatment of sleep disorders such as insomnia, obstructive sleep apnea, REM sleep behavior disorder, and restless legs syndrome. The book is written by medical and scientific experts in this field and intended for researchers from a range of disciplines such as biomedicine, biology, neurosciences, clinical medicine, neurology, and pharmacology.

The Science of Medical Cannabis

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Publisher :
ISBN 13 : 9781536145663
Total Pages : 144 pages
Book Rating : 4.1/5 (456 download)

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Book Synopsis The Science of Medical Cannabis by : David S. Younger

Download or read book The Science of Medical Cannabis written by David S. Younger and published by . This book was released on 2018-11-14 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cultural, scientific and legislative divide created by vigorous debates over the legalization of medical marijuana is giving way to a new synergy among community stakeholders across the United States. The goal is to improve access to medical marijuana for patients with refractory debilitating neurological disorders, cancer, and chronic pain as an alternative to ineffective pharmacotherapy and potentially addictive pain medications. The ultimate test of our nations resolve to ensure the welfare of our sickest patients is the enactment and implement of effective public health reform in the area of medical marijuana, also known as medical cannabis.This book evolved out of the present need for a definitive volume on the science and public health aspects of medical cannabis to fuel this national narrative. The ethnographic research presented in the concluding chapter was inspired by Professor Miriam W. Boeri and colleagues, at Bentley University in Waltham, MA. They examined views of community stakeholders including medical marijuana dispensary entrepreneurs, health care professionals, and patients in a state that legalized medical marijuana in 2013, yet there continued to be confusion and misunderstandings in the interpretation and implementation of medical marijuana guidelines during the period of policy shifts. Apparent gaps in policy development and implementation signaled the urgency for a comparison study addressing stakeholder views in New York State, where its medical marijuana program has legally dispensed the drug since 2014. The resulting pilot study was carried out in the Division of Health Policy and Management of the City University of New York School of Public Health. The research model incorporated ethnographic and grounded methodologies to detail the views of physicians, pharmacists, educators, patients, and entrepreneur stakeholders; with triangulation of data and application of dominant themes into a socioecological framework model to identify areas of public health policy reform. The findings of this study detail that New York, like other states that recently legalized the dispensation of medical marijuana, faces challenges beyond policy transparency, communication and education explicitly to improve the implementation process for applying and registering medical cannabis dispensaries, referring physicians, and qualified patient recipients.Ken Langone, Chairman of the Board of New York University Langone Health, and Steven Galetta, Chair of Neurology in the School of Medicine, where the authors is senior staff in neuroepidemiology, motivated him to pursue doctoral training in Health Policy and Management. The author has had the good fortune of interacting with thought-provoking medical students, neurology trainees, public health doctoral students, and professors who reinforce the high ethical standards in medical and public health practice and research. However, his patients still educate him in empathy and humanity. The author is grateful to his family, including his spouse Holly and sons Adam and Seth, who serve as his daily compass, encouraging him to take on projects that promote core values of medicine and humanity.

The Cannabinoids

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Publisher :
ISBN 13 :
Total Pages : 944 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Cannabinoids by : Stig Agurell

Download or read book The Cannabinoids written by Stig Agurell and published by . This book was released on 1984 with total page 944 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cannabinoids: Chemical, Pharmacologic, and Therapeutic Aspects provides a comprehensive discussion of the various aspects of cannabis and its constituents. The book is organized into six sections. Section I covers the clinical aspects of cannabis including the health aspects, impact on memory function, and the characteristics and treatment of marijuana abusers. Section II on chemical aspects includes studies on the chemistry and structure-activity relationships of cannabinoids; smoking characteristics of marijuana cigarettes; and developments in cannabinoid analyses of body fluids. Sectio ...

Phytocannabinoids

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Publisher : Springer
ISBN 13 : 3319455419
Total Pages : 137 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Phytocannabinoids by : A. Douglas Kinghorn

Download or read book Phytocannabinoids written by A. Douglas Kinghorn and published by Springer. This book was released on 2017-01-24 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents the current state of the art on phytocannnabinoid chemistry and pharmacology and will be of much use to those wishing to understand the current landscape of the exciting and intriguing phytocannabinoid science. The focus is on natural product cannabinoids which have been demonstrated to act at specific receptor targets in the CNS.

Cannabis

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Publisher : CRC Press
ISBN 13 : 1351398032
Total Pages : 406 pages
Book Rating : 4.3/5 (513 download)

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Book Synopsis Cannabis by : Betty Wedman-St.Louis

Download or read book Cannabis written by Betty Wedman-St.Louis and published by CRC Press. This book was released on 2018-04-19 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cannabis is one of the oldest cultivated plants dating back 12,000 years and demonstrates medicinal properties including immune support, anti-inflammatory effects, and cancer-fighting potential. As cannabis receives regulatory approval in the United States, clinicians will need guidelines to prescribe medical marijuana for various health conditions. This book presents information to healthcare professionals focusing on medical cannabis. It is a science-based overview providing clinical recommendations and dosing guidelines for practitioners to advise patients appropriately. Features: Discusses the endocannabinoid system role in homeostasis, pain control, and regulatory function in health and disease Advises clinicians on cannabis use in patients with cancer; cardiovascular, brain, and liver function; mood disorders; and patients receiving palliative care Includes information on cannabis nutrition as well as the cannabis microbiome Features information on cannabis quality control for safe and effective delivery Cannabis: A Clinician’s Guide is written for clinicians providing a resource guide to help them assess the medicinal value of cannabis, answer patient and consumer questions, and recommend its use optimally. The book is divided into three sections covering cannabis science, use in clinical practice, and regulations and standards. It includes practical information on dosing guidelines and dispensary insights, personal cannabis stories, and an in depth look at the nutritional benefits of cannabis and how to use it in daily life. From the Author: "As a clinical nutritionist, I have been involved in the use of cannabis since 1981 while researching diabetes in India. Ayurvedic medicine listed cannabis as a beneficial herb with curing properties. In 1983, a Chinese medicine doctor in the Peoples Republic of China gave me a cannabis herbal supplement for sleep that he claimed Chairman Mao took regularly. Upon returning to the United States, no one would even talk to me about cannabis because of its Schedule I status. During an Antioxidants class taught for Everglades University, I included information on cannabis, but was restricted from including it in the course description. Cannabis: A Clinician’s Guide unveils deceit on this herbal medicine used for thousands of years providing insight into the science behind its use and how to incorporate cannabis into daily life, especially for those suffering from neurological disorders, cancer, and mood disorders."

Clinical Practice Guidelines We Can Trust

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Author :
Publisher : National Academies Press
ISBN 13 : 030921646X
Total Pages : 217 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Clinical Practice Guidelines We Can Trust by : Institute of Medicine

Download or read book Clinical Practice Guidelines We Can Trust written by Institute of Medicine and published by National Academies Press. This book was released on 2011-06-16 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in medical, biomedical and health services research have reduced the level of uncertainty in clinical practice. Clinical practice guidelines (CPGs) complement this progress by establishing standards of care backed by strong scientific evidence. CPGs are statements that include recommendations intended to optimize patient care. These statements are informed by a systematic review of evidence and an assessment of the benefits and costs of alternative care options. Clinical Practice Guidelines We Can Trust examines the current state of clinical practice guidelines and how they can be improved to enhance healthcare quality and patient outcomes. Clinical practice guidelines now are ubiquitous in our healthcare system. The Guidelines International Network (GIN) database currently lists more than 3,700 guidelines from 39 countries. Developing guidelines presents a number of challenges including lack of transparent methodological practices, difficulty reconciling conflicting guidelines, and conflicts of interest. Clinical Practice Guidelines We Can Trust explores questions surrounding the quality of CPG development processes and the establishment of standards. It proposes eight standards for developing trustworthy clinical practice guidelines emphasizing transparency; management of conflict of interest ; systematic review-guideline development intersection; establishing evidence foundations for and rating strength of guideline recommendations; articulation of recommendations; external review; and updating. Clinical Practice Guidelines We Can Trust shows how clinical practice guidelines can enhance clinician and patient decision-making by translating complex scientific research findings into recommendations for clinical practice that are relevant to the individual patient encounter, instead of implementing a one size fits all approach to patient care. This book contains information directly related to the work of the Agency for Healthcare Research and Quality (AHRQ), as well as various Congressional staff and policymakers. It is a vital resource for medical specialty societies, disease advocacy groups, health professionals, private and international organizations that develop or use clinical practice guidelines, consumers, clinicians, and payers.