Clinical Application Of Radiolabelled Platelets

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Clinical Application of Radiolabelled Platelets

Author : C. Kessler
Publisher : Springer Science & Business Media
ISBN 13 : 9400905815
Total Pages : 307 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Clinical Application of Radiolabelled Platelets by : C. Kessler

Download or read book Clinical Application of Radiolabelled Platelets written by C. Kessler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: AIMS OF THE COLOGNE-SYMPOSIUM ON RADIOLABELLED PLATELETS In 1976, M. Thakur et al (1) were the first to publish a paper concerning the in vivo thrombus detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisation had been disappointing because of the unspecific binding of a number of the isotopes used, as well as the poor labelling efficiency or an insufficient low gamma-emitting property. Because of its physical characteristics (2.8 days half-life, 94% gamma emission) 111 Indium turned out to be the best isotope for platelet kinetic studies as well as for the measurement of platelet incorporation by Thrombi to be used up until now. The lipophile complexes of Ill-In (8-hydroxyquinoline, acetylacetone, tropolone) diffuse passively into the platelets without altering the function or the life span of the platelets. This advantage has let to an increase in the clinical applications of 1211-In labelled platelets. Today, radiolabelled platelets are used for thrombus detection in several different medical areas such as cardiology, nephrology. angiology or neurology. Even though many scientists and hospital doctors now routinely use radiolabelled platelet as a diagnostic tool, there is as yet not a standardized labelling method. In addition to this, there are neither standardized image procedures for the different clinical applications nor an agreement about specificity and sensitivity of the method. In 1983, a symposium on Radiolabelled Cellular Blood Elements was organized by M.Thakur, M.R.Hardeman and M.D.

Radiolabeled Blood Elements

Author : J. Martin-Comin
Publisher : Springer Science & Business Media
ISBN 13 : 1461524628
Total Pages : 354 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Radiolabeled Blood Elements by : J. Martin-Comin

Download or read book Radiolabeled Blood Elements written by J. Martin-Comin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scintigraphic imaging with radiolabeled blood elements has continued to be a useful diagnostic modality. The major trust of recent investigation has been in simplifying labeling techniques and developing new agents that will label blood elements selectively in vitro. The VI Symposium of the International Society of Radiolabeled Blood Elements was held in Barcelona (Spain) during November 23 to 27, 1992.The conference was sponsored by the NATO Scientific Affairs Division, the USA Department of Energy and the Spanish National Health Service. This monograph comprises articles that represent most of the 85 papers (70 oral and 15 posters) presented during the symposium. The meeting was attended by 110 investigators hailed from 21 countries. Although lllIn-oxine and 99mTc-HMPAO remain the choice agents for labeling blood components for routine applications, there was heavy emphasis on developing new labeling agents that will either simplify the in vitro labeling procedure, or, even better, will label blood components selectively in vivo, by injecting the radioactive agents directly into patients. The degree of success in imaging target lesions in humans by using these agents has been excellent.

Radiolabeled Cellular Blood Elements

Author : M. L. Thakur
Publisher : Springer Science & Business Media
ISBN 13 : 1468449222
Total Pages : 435 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Radiolabeled Cellular Blood Elements by : M. L. Thakur

Download or read book Radiolabeled Cellular Blood Elements written by M. L. Thakur and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preparing manuscripts with figures and tables for camera repro duction was a formidable task. Care has been taken for consistency and typographic accuracy. However, I make no claim that no errors exist in this volume. ,I hope, however, that the reader will under stand and ignore any error and find this compendious volume useful for numerous biologic studies, physiologic explorations and clinical app lications of radiolabeled cellular blood elements in years to come. M. L. Thakur Editor, and the ASI Director ACKNOWLEDGEMENTS Dr. Max Hardeman of the University of Amsterdam and Dr. Michael Ezekowitz of Yale University served as the codirectors of the Advanced Study Institute (ASI). Dr. Hardeman spent countless hours and contri buted to the scientific program, took care of mailings in Europe, organized transportation in Italy, and communicated with the hotel management on numerous occasions. I cannot thank him enough! Dr. Ezekowitz collected some manuscripts and corrected a few. I am grateful to him. I take this opportunity once again to thank all the guest fac ulty, who, despite their busy schedules and time constraints, accepted my invitation and made valuable contributions to the ASI. I am also grateful to all participants, who were so friendly and were primary resources for many lively discussions. They made the ASI profession ally beneficial and socially enjoyable.

Brain Dopaminergic Systems: Imaging with Positron Tomography

Author : J.C Baron
Publisher : Springer Science & Business Media
ISBN 13 : 9401135282
Total Pages : 206 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Brain Dopaminergic Systems: Imaging with Positron Tomography by : J.C Baron

Download or read book Brain Dopaminergic Systems: Imaging with Positron Tomography written by J.C Baron and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging of the Dopaminergic system in the human brain with the in vivo use of Positron Emis sion Tomography has emerged in the late 1980s as a tool of major importance in Clinical Neuros ciences and Pharmacology. The last few years have witnessed the rapid development of new radiotracers specific to receptors, reuptake sites and enzymes of the dopamine system; the application of these radiotracers has led to major breakthroughs in the pathophysiology and therapy of movement disorders and schizophrenic-like psychoses. This book is the first to collect, in a single volume, state-of-the-art contributions to the various aspects of this research. Its contents address methodological issues related to the design, labelling, quantitative imaging and compartmental modelisation of radioligands of the post-synaptic, pre-synaptic and enzyme sites of the dopamine system and to their use in clinical research in the fields of Parkinson's disease as well as other movement disorders, psychoses and neuroleptic receptor occupancy. The chapters were written by leading European scientists in the field of Positron Emission Tomography, gathered together in Caen (France, November 1990) under the aegis of the EEC Concerted Action on "PET Investigations of Cellular Regeneration and Degeneration. This book provides a current and comprehensive overview on PET studies of the brain dopamine system which should aid and interest neurologists, psychiatrists, pharmacologists and medical imaging scientists. J.C. Baron D. Comar L. Farde J.L. Martinot B. Mazoyer August 1991 ix LIST OF CONTRffiUTORS Dr Yves Agid DrL.

Radiopharmaceuticals for Positron Emission Tomography - Methodological Aspects

Author : G. Stöcklin
Publisher : Springer Science & Business Media
ISBN 13 : 9780792323402
Total Pages : 210 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Radiopharmaceuticals for Positron Emission Tomography - Methodological Aspects by : G. Stöcklin

Download or read book Radiopharmaceuticals for Positron Emission Tomography - Methodological Aspects written by G. Stöcklin and published by Springer Science & Business Media. This book was released on 1993-06-30 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiochemical methodology constitutes the most important base for the successful functioning of a PET group in the routine production and development of radiopharmaceuticals. Of the several hundred products which have been labelled with positron emitters during the past two decades about 35 are presently considered to be of major interest. The time for a state-of-the-art review is right, since this field has advanced over the past fifteen years to reach a level where guidelines can now be suggested. Chapters of this book deal with each of the main methodological aspects of the chemistry needed to develop an effective radiopharmaceutical, namely radionuclide production, automation and metabolite analysis. A further chapter on QA/QC is written by a broadly-based expert group and is meant to provide a guideline and a base for future monographs and regulations on major PET radiopharmaceuticals of today. This book will help the increasing numbers of scientists who are now entering the field of PET to appreciate the methodological aspects that are normally addressed by chemists in relation to PET radiopharmaceuticals; it provides many useful practical guidelines and will promote early success in their own endeavours, since these will often necessarily begin by establishing chemical methodology of the kind discussed here.

National Library of Medicine Current Catalog

Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 1032 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1990 with total page 1032 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Radiolabelled Cellular Blood Elements

Author : Helmut Sinzinger
Publisher :
ISBN 13 :
Total Pages : 414 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Radiolabelled Cellular Blood Elements by : Helmut Sinzinger

Download or read book Radiolabelled Cellular Blood Elements written by Helmut Sinzinger and published by . This book was released on 1990 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Current Catalog

Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 1024 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Current Catalog by : National Library of Medicine (U.S.)

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1024 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Clinical Nuclear Medicine

Author : K. E. Britton
Publisher : Springer
ISBN 13 : 1489933565
Total Pages : 757 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Clinical Nuclear Medicine by : K. E. Britton

Download or read book Clinical Nuclear Medicine written by K. E. Britton and published by Springer. This book was released on 2013-11-11 with total page 757 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear medicine is the bridge between a particular clinical problem and a relevant test using radionuclides. It began as a minor technical tool used in a few branches of medicine, notably endocrinology and nephrology. However, throughout the world it has now become established as a clinical discipline in its own right, with specific training programmes, special skills and a particular approach to patient management. Although the practising nuclear medicine physician must necessarily learn a great deal of basic science and technology, a sound medical training and a clinical approach to the subject remains of fundamental importance. It is for this reason that we have attempted in this book to approach the subject from a clinical standpoint, including where necessary relevant physiological material. There exist many excellent texts which cover the basic science and technology of nuclear medicine. We have, therefore, severely limited our coverage of these aspects of the subject to matters which we felt to be essential, particularly those which have been less well covered in other texts - for example, the contents of Chapter 21 on Quantitation by Royal and McNeil. Similarly, we have included at the end of some chapters descriptions of particular techniques where we and the authors felt that it would be helpful. In order to emphasize the clinical approach of this book we have inverted the traditional sequence of material in chapters, presenting the clinical problems first in each instance.

Platelets and Their Factors

Author : Franz von Bruchhausen
Publisher : Springer Science & Business Media
ISBN 13 : 3642606393
Total Pages : 771 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Platelets and Their Factors by : Franz von Bruchhausen

Download or read book Platelets and Their Factors written by Franz von Bruchhausen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 771 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platelets playa fundamental, life-saving role in hemostasis and blood clotting at sites of vascular injury. Unwanted platelet activation and arterial thombus formation are, however, implicated in the onset of myocardial infarction, stroke, and other cardiovascular diseases. Acceptance that platelets play a major role in the pathogenesis of atherosclerosis including coronary heart disease has revolutionized the pharmacological treatment of cardiovascular diseases, and aspirin is now an essential antiplatelet drug and the golden standard for future developments. Yet the search for better and perhaps safer antiplatelet drugs is one of the most active areas of investigation in both basic and clinical research. Platelets, especially human platelets, have also emerged as one of the major models for the study of inter- and intracellular signal transduction pathways. Many biochemists, cell biologists, pharmacologists, pathologists, hematologists, and cardiologists find platelets useful for studying processes such as adhesion, inside-out and outside-in signalling through the plasma membrane, channels, calcium homeostasis, protein kinases, the network of intracellular signal transduction cascades, and the release of vasoactive substances. The aim of the editors has been to compile chapters summarizing the current state-of-the-art information on the biochemistry, cell biology, pharmacology, and physiologic and pathophysiologic roles of human platelets. We hope that this volume represents the major aspects of current platelet research although it is perhaps inevitable that certain areas are covered less thoroughly than others. We would like to acknowledge the excellent help and support of the Springer-Verlag staff, in particular that of Ms. Doris Walker.

Library of Congress Subject Headings

Author : Library of Congress
Publisher :
ISBN 13 :
Total Pages : 1712 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Library of Congress Subject Headings by : Library of Congress

Download or read book Library of Congress Subject Headings written by Library of Congress and published by . This book was released on 1991 with total page 1712 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Library of Congress Subject Headings

Author : Library of Congress. Office for Subject Cataloging Policy
Publisher :
ISBN 13 :
Total Pages : 1698 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Library of Congress Subject Headings by : Library of Congress. Office for Subject Cataloging Policy

Download or read book Library of Congress Subject Headings written by Library of Congress. Office for Subject Cataloging Policy and published by . This book was released on 1991 with total page 1698 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Library of Congress Subject Headings

Author : Library of Congress. Cataloging Policy and Support Office
Publisher :
ISBN 13 :
Total Pages : 1596 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Library of Congress Subject Headings by : Library of Congress. Cataloging Policy and Support Office

Download or read book Library of Congress Subject Headings written by Library of Congress. Cataloging Policy and Support Office and published by . This book was released on 2009 with total page 1596 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cumulative Book Index

Author :
Publisher :
ISBN 13 :
Total Pages : 2328 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cumulative Book Index by :

Download or read book Cumulative Book Index written by and published by . This book was released on 1995 with total page 2328 pages. Available in PDF, EPUB and Kindle. Book excerpt: A world list of books in the English language.

P-Z

Author : Library of Congress. Office for Subject Cataloging Policy
Publisher :
ISBN 13 :
Total Pages : 1644 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis P-Z by : Library of Congress. Office for Subject Cataloging Policy

Download or read book P-Z written by Library of Congress. Office for Subject Cataloging Policy and published by . This book was released on 1990 with total page 1644 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Library of Congress Subject Headings: F-O

Author : Library of Congress. Subject Cataloging Division
Publisher :
ISBN 13 :
Total Pages : 1452 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Library of Congress Subject Headings: F-O by : Library of Congress. Subject Cataloging Division

Download or read book Library of Congress Subject Headings: F-O written by Library of Congress. Subject Cataloging Division and published by . This book was released on 1988 with total page 1452 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mollison's Blood Transfusion in Clinical Medicine

Author : Harvey G. Klein
Publisher : John Wiley & Sons
ISBN 13 : 1405199407
Total Pages : 956 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Mollison's Blood Transfusion in Clinical Medicine by : Harvey G. Klein

Download or read book Mollison's Blood Transfusion in Clinical Medicine written by Harvey G. Klein and published by John Wiley & Sons. This book was released on 2014-02-03 with total page 956 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mollison's Blood Transfusion in Clinical Medicine is an icon in the field of transfusion and the first edition was published in 1951. The book arose from the concept of the transfusionist, as both scientist and expert consultant. For many years, this text has provided the primary, and often the sole, reference for detailed information and practical experience in blood transfusion. The book is completely revised and updated throughout to include the latest advances and developments in the field.