Circadian Clocks: Role in Health and Disease

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Author :
Publisher : Springer
ISBN 13 : 1493934503
Total Pages : 378 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Circadian Clocks: Role in Health and Disease by : Michelle L. Gumz

Download or read book Circadian Clocks: Role in Health and Disease written by Michelle L. Gumz and published by Springer. This book was released on 2016-02-29 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book sheds new light on the molecular mechanisms that generate circadian rhythms. It examines how biological rhythms influence physiological processes such as sleep, hormone synthesis and secretion, immunity, kidney function, the cardiovascular system, blood pressure, and the digestive system. Clinical implications are considered while exploring the impact of rhythms on neuropsychiatric disorders and chronotherapy’s potential for reducing cardiovascular risk. Offering a cross-section of expertise in both basic and translational (bench-to-bedside) research, this book serves as a guide for physicians and scientists who wish to learn more about the impact of circadian rhythms on physiological processes in health and disease.

Circadian Rhythms in Bacteria and Microbiomes

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Author :
Publisher : Springer Nature
ISBN 13 : 3030721582
Total Pages : 424 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Circadian Rhythms in Bacteria and Microbiomes by : Carl Hirschie Johnson

Download or read book Circadian Rhythms in Bacteria and Microbiomes written by Carl Hirschie Johnson and published by Springer Nature. This book was released on 2021-06-21 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses multiple aspects of biological clocks in prokaryotes. The first part of the book deals with the circadian clock system in cyanobacteria, i.e. the pioneer of bacterial clocks. Starting with the history and background of cyanobacteria and circadian rhythms in microorganisms, the topics range from the molecular basis, structure and evolution of the circadian clock to modelling approaches, Kai systems in cyanobacteria and biotechnological applications. In the second part, emergent timekeeping properties of bacteria in microbiomes and bacteria other than cyanobacteria are discussed. Since the discovery of circadian rhythms in cyanobacteria in the late 1980s, the field has exploded with new information. The cyanobacterial model system for studying circadian rhythms (Synechococcus elongatus), has allowed a detailed genetic dissection of the bacterial clock due to state-of-the-art methods in molecular, structural, and evolutionary biology. Cutting-edge research spanning from cyanobacteria and circadian phenomena in other kinds of bacteria, to microbiomes has now given the field another major boost. This book is aimed at junior and senior researchers alike. Students or researchers new to the field of biological clocks in prokaryotes will get a comprehensive overview, while more experienced researchers will get an update on the latest developments.

Circadian Clocks

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Author :
Publisher : Humana
ISBN 13 : 9781071603833
Total Pages : 342 pages
Book Rating : 4.6/5 (38 download)

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Book Synopsis Circadian Clocks by : Steven A. Brown

Download or read book Circadian Clocks written by Steven A. Brown and published by Humana. This book was released on 2021-12-22 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Circadian Clock

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1441912622
Total Pages : 300 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis The Circadian Clock by : Urs Albrecht

Download or read book The Circadian Clock written by Urs Albrecht and published by Springer Science & Business Media. This book was released on 2010-01-23 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.

Circadian Clocks

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642259502
Total Pages : 414 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Circadian Clocks by : Achim Kramer

Download or read book Circadian Clocks written by Achim Kramer and published by Springer Science & Business Media. This book was released on 2013-04-18 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with a contemporary and comprehensive overview about the molecular, cellular and system-wide principles of circadian clock regulation. Emphasis is placed on the importance of circadian clocks for the timing of therapeutic interventions.

Circadian Medicine

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Publisher : John Wiley & Sons
ISBN 13 : 1118467787
Total Pages : 405 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Circadian Medicine by : Christopher S. Colwell

Download or read book Circadian Medicine written by Christopher S. Colwell and published by John Wiley & Sons. This book was released on 2015-07-07 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Circadian rhythms, the biological oscillations based around our 24-hour clock, have a profound effect on human physiology and healthy cellular function. Circadian Rhythms: Health and Disease is a wide-ranging foundational text that provides students and researchers with valuable information on the molecular and genetic underpinnings of circadian rhythms and looks at the impacts of disruption in our biological clocks in health and disease. Circadian Rhythms opens with chapters that lay the fundamental groundwork on circadian rhythm biology. Section II looks at the impact of circadian rhythms on major organ systems. Section III then turns its focus to the central nervous system. The book then closes with a look at the role of biological rhythms in aging and neurodegeneration. Written in an accessible and informative style, Circadian Rhythms: Health and Disease,will be an invaluable resource and entry point into this fascinating interdisciplinary field that brings together aspects of neuroscience, cell and molecular biology, and physiology.

Circadian Clock in Brain Health and Disease

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Author :
Publisher : Springer Nature
ISBN 13 : 3030811476
Total Pages : 193 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Circadian Clock in Brain Health and Disease by : Olivia Engmann

Download or read book Circadian Clock in Brain Health and Disease written by Olivia Engmann and published by Springer Nature. This book was released on 2021-11-13 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, leading experts in the field review how circadian rhythms impact the brain. An essential function of mammalian life is the exploitation of the regularities provided by the 24-hour cycle of day and night. The development and evolution of circadian clock mechanisms have allowed us to optimally adapt our behavior and physiology to the external world. Not surprisingly, a growing body of evidence links the disruption of circadian rhythms by genetic, lifestyle and environmental factors to illnesses of the brain. In the first section of the book, readers will learn about the molecular and anatomic architecture of circadian function in mammals. The ways in which environmental disruptions and misalignments can influence such mechanisms and therefore impair brain function and health status are also addressed. In the second part, the focus shifts to those brain regions responsible for brain function and the body-wide regulation of circadian function. Amongst others, special attention is paid to the role of astrocytes and the brain’s reward and hyprocretin / orexin systems. The book concludes with an extensive discussion on the consequences of circadian rhythm dysfunction. Several chapters present the latest findings on Attention Deficit Hyperactivity Disorder, schizophrenia, autism spectrum disorder, drug abuse and mood disorders. Written by auhorities in the field, the book provides a state-of-the-art review of the latest findings on circadian clocks in the brain and highlights their potentially far-reaching impacts on our health and well-being. As such, it is essential reading for all neuroscientists and clinicians seeking to understand the intricate connections between circadian rhythms and brain health and illness.

Human Circadian Physiology

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Author :
Publisher :
ISBN 13 :
Total Pages : 692 pages
Book Rating : 4.:/5 (84 download)

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Book Synopsis Human Circadian Physiology by : Charles A. Czeisler

Download or read book Human Circadian Physiology written by Charles A. Czeisler and published by . This book was released on 1978 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Circadian Rhythms

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Author :
Publisher : Oxford University Press
ISBN 13 : 0198717687
Total Pages : 169 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Circadian Rhythms by : Russell G. Foster

Download or read book Circadian Rhythms written by Russell G. Foster and published by Oxford University Press. This book was released on 2017 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explains how organisms can 'know' the time and reveals what we now understand of the nature and operation of chronobiological processes. Covering variables such as light, the metabolism, human health, and the seasons, Foster and Kreitzman illustrate how jet lag and shift work can impact on human well-being.--

A Time for Metabolism and Hormones

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Publisher : Springer
ISBN 13 : 3319270699
Total Pages : 132 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis A Time for Metabolism and Hormones by : Paolo Sassone-Corsi

Download or read book A Time for Metabolism and Hormones written by Paolo Sassone-Corsi and published by Springer. This book was released on 2016-04-04 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

Circadian Rhythms

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Author :
Publisher : Perspectives Cshl
ISBN 13 : 9781621821243
Total Pages : 232 pages
Book Rating : 4.8/5 (212 download)

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Book Synopsis Circadian Rhythms by : Akhilesh B. Reddy

Download or read book Circadian Rhythms written by Akhilesh B. Reddy and published by Perspectives Cshl. This book was released on 2018 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our daily routines and physiological functions-and those of virtually all living organisms-are synchronized with the Earth's rotation about its axis. These include sleep patterns, hormone secretion, blood pressure, body temperature, and feeding behavior. Oscillations in these processes, or circadian rhythms, are controlled by molecular feedback loops that integrate with environmental and metabolic stimuli. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines the molecular and cellular details of the oscillatory machinery and how they control aspects of our physiology. Contributors discuss the cell-autonomous generation of circadian time and how those mechanisms interact with circuit-level mechanisms in the suprachiasmatic nucleus. Links between circadian and redox systems, as well as the relationship between circadian oscillations and pathogenic infections, are also covered. In addition, the authors examine circadian rhythms in other species (e.g., plants and Drosophila) and how they enable the organisms to adapt to their environments. This volume will therefore serve as a valuable reference for not only neurobiologists and cell and molecular biologists, but all who wish to understand the clocks and rhythms of life.

Insect Timing

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Publisher : Gulf Professional Publishing
ISBN 13 : 044450608X
Total Pages : 245 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Insect Timing by : D.L. Denlinger

Download or read book Insect Timing written by D.L. Denlinger and published by Gulf Professional Publishing. This book was released on 2001-06-19 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now that many of the clock genes have been identified it is possible to track daily patterns of clock-related mRNAs and proteins to link the entraining light cycles with molecular oscillations within the cell. Insect experiments have led the way in demonstrating that the concept of a "master clock" can no longer be used to explain the temporal organization within an animal. Insects have a multitude of cellular clocks that can function independently and retain their function under organ culture conditions, and they thus offer a premier system for studying how the hierarchical organization of clocks results in the overall temporal organization of the animal. Photoperiodism, and its most obvious manifestation, diapause, does not yet have the molecular underpinning that has been established for circadian rhythms, but recent studies are beginning to identify genes that appear to be involved in the regulation of diapause.

Biological Clocks, Rhythms, and Oscillations

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Author :
Publisher : MIT Press
ISBN 13 : 0262036770
Total Pages : 369 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Biological Clocks, Rhythms, and Oscillations by : Daniel B. Forger

Download or read book Biological Clocks, Rhythms, and Oscillations written by Daniel B. Forger and published by MIT Press. This book was released on 2017-11-16 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the mathematical, computational, and analytical techniques used for modeling biological rhythms, presenting tools from many disciplines and example applications. All areas of biology and medicine contain rhythms, and these behaviors are best understood through mathematical tools and techniques. This book offers a survey of mathematical, computational, and analytical techniques used for modeling biological rhythms, gathering these methods for the first time in one volume. Drawing on material from such disciplines as mathematical biology, nonlinear dynamics, physics, statistics, and engineering, it presents practical advice and techniques for studying biological rhythms, with a common language. The chapters proceed with increasing mathematical abstraction. Part I, on models, highlights the implicit assumptions and common pitfalls of modeling, and is accessible to readers with basic knowledge of differential equations and linear algebra. Part II, on behaviors, focuses on simpler models, describing common properties of biological rhythms that range from the firing properties of squid giant axon to human circadian rhythms. Part III, on mathematical techniques, guides readers who have specific models or goals in mind. Sections on “frontiers” present the latest research; “theory” sections present interesting mathematical results using more accessible approaches than can be found elsewhere. Each chapter offers exercises. Commented MATLAB code is provided to help readers get practical experience. The book, by an expert in the field, can be used as a textbook for undergraduate courses in mathematical biology or graduate courses in modeling biological rhythms and as a reference for researchers.

The Circadian Code

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Author :
Publisher : Rodale Books
ISBN 13 : 0593135903
Total Pages : 290 pages
Book Rating : 4.5/5 (931 download)

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Book Synopsis The Circadian Code by : Satchin Panda, PhD

Download or read book The Circadian Code written by Satchin Panda, PhD and published by Rodale Books. This book was released on 2020-02-11 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: When we eat may be as important as what we eat. Like most people, you probably wake up, get hungry for meals and doze off in bed around the same time every day. If you’ve ever experienced jet lag or pulled an all-nighter, you know that this schedule can easily be thrown off kilter. But for some people, that imbalance—difficulty sleeping at night, hunger at odd times, or sudden fatigue at noon—is a constant. If you're one of those people, Dr. Satchin Panda, one of the leading researchers on circadian rhythms, has a plan to reset your body clock. Beginning with an in-depth explanation of the circadian clock—why it’s important, how it works, and how to know it isn’t working—The Circadian Code outlines lifestyle changes to make to get back on track. It's a concrete plan to enhance weight loss, improve sleep, optimize exercise, and manage technology so that it doesn’t interfere with your body’s natural rhythm. Dr. Panda’s life changing methods show you how to prevent and reverse ailments like diabetes, cancer, and dementia, as well as microbiome conditions like acid reflux, heartburn, and irritable bowel disease.

The Rhythms Of Life

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Publisher : Profile Books
ISBN 13 : 1847653723
Total Pages : 469 pages
Book Rating : 4.8/5 (476 download)

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Book Synopsis The Rhythms Of Life by : Leon Kreitzman

Download or read book The Rhythms Of Life written by Leon Kreitzman and published by Profile Books. This book was released on 2011-09-30 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Popular science at its most exciting: the breaking new world of chronobiology - understanding the rhythm of life in humans and all plants and animals. The entire natural world is full of rhythms. The early bird catches the worm -and migrates to an internal calendar. Dormice hibernate away the winter. Plants open and close their flowers at the same hour each day. Bees search out nectar-rich flowers day after day. There are cicadas that can breed for only two weeks every 17 years. And in humans: why are people who work anti-social shifts more illness prone and die younger? What is jet-lag and can anything help? Why do teenagers refuse to get up in the morning, and are the rest of us really 'larks' or 'owls'? Why are most people born (and die) between 3am-5am? And should patients be given medicines (and operations) at set times of day, because the body reacts so differently in the morning, evening and at night? The answers lie in our biological clocks the mechanisms which give order to all living things. They impose a structure that enables us to change our behaviour in relation to the time of day, month or year. They are reset at sunrise and sunset each day to link astronomical time with an organism's internal time.

Molecular Biology of Circadian Rhythms

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 9780471418245
Total Pages : 302 pages
Book Rating : 4.4/5 (182 download)

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Book Synopsis Molecular Biology of Circadian Rhythms by : Amita Sehgal

Download or read book Molecular Biology of Circadian Rhythms written by Amita Sehgal and published by John Wiley & Sons. This book was released on 2004-04 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text begins with a general introduction to biochemical and biophysical aspects of circadian timing, then proceeds to its essential focus on collating the newest information on molecular mechanisms of circadian rhythms. It includes a chapter on the implications for clinical research on affective disorders, sleep disorders, and the relevance for therapeutic treatment, as well as coverage of multiple oscillators and hormonal rhythms. Sections include: Molecular Control of Circadian Rhythms: Animal Models Molecular Control of Circadian Rhythms: From Cyanobacteria to Plants Circadian Organization in Complex Organisms. Chapter topics include examinations of circadian rhythms in non-mammalian vertebrates, neurospora, and humans.

Circadian Clocks

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9780306465048
Total Pages : 820 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis Circadian Clocks by : Joseph S. Takahashi

Download or read book Circadian Clocks written by Joseph S. Takahashi and published by Springer Science & Business Media. This book was released on 2001-09-30 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nature of the circadian clocks is described at the molecular, cellular, tissue, and system levels of organization in diverse organisms. The central role of the circadian clock in the regulation of the sleep-wake cycle as well as seasonal rhythms and other cyclical processes is also discussed. The importance of the circadian clock system for human health, safety, performance, and productivity is also reviewed in this volume."--BOOK JACKET.