Cancer Cytogenetics

Download Cancer Cytogenetics PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118795512
Total Pages : 645 pages
Book Rating : 4.1/5 (187 download)

DOWNLOAD NOW!


Book Synopsis Cancer Cytogenetics by : Sverre Heim

Download or read book Cancer Cytogenetics written by Sverre Heim and published by John Wiley & Sons. This book was released on 2015-06-29 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first three editions of this acclaimed book presented a much-needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations. New contributors reflecting broader international authorship and even greater expertise Greater emphasis throughout on the clinical importance and application of information about cytogenetic and molecular aberrations Includes a complete coverage of chromosome aberrations in cancer based on an assessment of the 60,000 neoplasms cytogenetically investigated to date Now produced in full color for enhanced clarity Covers how molecular genetic data (PCR-based and sequencing information) are collated with the cytogenetic data where pertinent Discusses how molecular cytogenetic data (based on studies using FISH, CGH, SNP, etc) are fused with karyotyping data to enable an as comprehensive understanding of cancer cytogenetics as is currently possible

The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment

Download The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment PDF Online Free

Author :
Publisher : The Experiment, LLC
ISBN 13 : 1615191658
Total Pages : 345 pages
Book Rating : 4.6/5 (151 download)

DOWNLOAD NOW!


Book Synopsis The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment by : Jessica Wapner

Download or read book The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment written by Jessica Wapner and published by The Experiment, LLC. This book was released on 2014-04-08 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of The Wall Street Journal’s 10 Best Nonfiction Books of the Year Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research— the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same. Science journalist Jessica Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute—with extensive original reporting, including more than thirty-five interviews—to the dozens of researchers, doctors, and patients with a direct role in this inspirational story. Their curiosity and determination would ultimately lead to a lifesaving treatment unlike anything before it. The Philadelphia Chromosome chronicles the remarkable change of fortune for the more than 70,000 people worldwide who are diagnosed with CML each year. It is a celebration of a rare triumph in the battle against cancer and a blueprint for future research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

Molecular Biology of the Cell

Download Molecular Biology of the Cell PDF Online Free

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

DOWNLOAD NOW!


Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Role of Chromosomes in Cancer Biology

Download The Role of Chromosomes in Cancer Biology PDF Online Free

Author :
Publisher : Butterworth-Heinemann
ISBN 13 : 1483192911
Total Pages : 137 pages
Book Rating : 4.4/5 (831 download)

DOWNLOAD NOW!


Book Synopsis The Role of Chromosomes in Cancer Biology by : Peo C. Kollerr

Download or read book The Role of Chromosomes in Cancer Biology written by Peo C. Kollerr and published by Butterworth-Heinemann. This book was released on 2017-07-22 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Role of Chromosomes in Cancer Biology provides a description of the molecular organization and function of chromosomes and the consequences of chromosomal aberrations in human development. The book presents accounts on the structure and function of the chromosome; the cellular features of primary tumors and ascetic fluid; the cytological actions of radiation and drugs and their relevance to therapy. Developmental disorders caused by chromosomal anomalies; chromosome aneuploidy in human malignancies; and viral oncogenesis are discussed as well. The book will prove to be very insightful to those involved in cancer research, oncologists, cytologists, and molecular biologists.

The Causes and Consequences of Chromosomal Aberrations

Download The Causes and Consequences of Chromosomal Aberrations PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 9780849388934
Total Pages : 556 pages
Book Rating : 4.3/5 (889 download)

DOWNLOAD NOW!


Book Synopsis The Causes and Consequences of Chromosomal Aberrations by : Ilan R. Kirsch

Download or read book The Causes and Consequences of Chromosomal Aberrations written by Ilan R. Kirsch and published by CRC Press. This book was released on 1992-12-21 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Causes and Consequences of Chromosomal Aberrations explores one of the most dramatic examples of genomic instability-chromosomal aberrations. It describes some of the more recent techniques used to map genes within the human genome, study chromosomal aberrations at the cellular level, and define the organization of the interphase nucleus. General overviews are provided to build a conceptual framework for understanding the generality and specificity of chromosomal aberrations. The Causes and Consequences of Chromosomal Aberrations also explores the role of recombinases and topoisomerases in the development of chromosomal aberrations. It contains studies of chromosomal aberrations, which offer separate instructive treatises on specific malignancies. The Causes and Consequences of Chromosomal Aberrations is useful to medical and graduate students, physicians, molecular biologists, and cytogeneticists. It will benefit anyone interested in the concepts, contributions, and development in the field of molecular cytogenetics.

Genome Chaos

Download Genome Chaos PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128136367
Total Pages : 556 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!


Book Synopsis Genome Chaos by : Henry H. Heng

Download or read book Genome Chaos written by Henry H. Heng and published by Academic Press. This book was released on 2019-05-25 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine transports readers from Mendelian Genetics to 4D-genomics, building a case for genes and genomes as distinct biological entities, and positing that the genome, rather than individual genes, defines system inheritance and represents a clear unit of selection for macro-evolution. In authoring this thought-provoking text, Dr. Heng invigorates fresh discussions in genome theory and helps readers reevaluate their current understanding of human genetics, evolution, and new pathways for advancing molecular and precision medicine. Bridges basic research and clinical application and provides a foundation for re-examining the results of large-scale omics studies and advancing molecular medicine Gathers the most pressing questions in genomic and cytogenomic research Offers alternative explanations to timely puzzles in the field Contains eight evidence-based chapters that discuss 4d-genomics, genes and genomes as distinct biological entities, genome chaos and macro-cellular evolution, evolutionary cytogenetics and cancer, chromosomal coding and fuzzy inheritance, and more

The Chromosomes in Human Cancer and Leukemia

Download The Chromosomes in Human Cancer and Leukemia PDF Online Free

Author :
Publisher : Elsevier Science & Technology
ISBN 13 :
Total Pages : 784 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis The Chromosomes in Human Cancer and Leukemia by : Avery A. Sandberg

Download or read book The Chromosomes in Human Cancer and Leukemia written by Avery A. Sandberg and published by Elsevier Science & Technology. This book was released on 1980 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Holland-Frei Cancer Medicine

Download Holland-Frei Cancer Medicine PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2004 pages
Book Rating : 4.1/5 (19 download)

DOWNLOAD NOW!


Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Abnormal Chromosomes

Download Abnormal Chromosomes PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119652057
Total Pages : 211 pages
Book Rating : 4.1/5 (196 download)

DOWNLOAD NOW!


Book Synopsis Abnormal Chromosomes by : Sverre Heim

Download or read book Abnormal Chromosomes written by Sverre Heim and published by John Wiley & Sons. This book was released on 2022-02-15 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore the past, present, and future of cancer cytogenetics In Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics, globally renowned researchers Drs. Sverre Heim and Felix Mitelman deliver a state-of-the-art review of how cancer cytogenetic analyses have contributed to an improved understanding of tumorigenesis as well as to the diagnosis and treatment of cancer patients. The book also discusses how cytogenetics – the study of chromosomes - meets, interacts with, and cross-fertilizes other investigative technologies, including molecular somatic cell genetics. The book provides an impetus to think more deeply about the role chromosomes, and their abnormalities, play in health and disease, especially in neoplastic disorders. From which origins did cytogenetics develop? How did the finding of acquired chromosomal abnormalities in cells of leukemias and solid tumors influence our understanding of cancer as a biological process? How was information of this nature put to good use in the clinical management of cancer patients? Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics offers readers: A thorough introduction to ancient theories of disease, the advent of cellular pathology, and how a scientific interest in chromosomes developed Comprehensive exploration of the conceptual importance of Theodor Boveri and his somatic mutation theory of cancer A detailed chronological resume of cancer cytogenetic discoveries during the 20th century In-depth discussions of the role of chromosome abnormalities, oncogenes, and tumor suppressor genes in leukemias, lymphomas, and solid tumors, together with a survey of what chromosome analyses have revealed about the clonal evolution of neoplastic cell populations A discussion of the importance of pathogenetic classifications of neoplastic diseases, the role chromosome abnormalities play in this context, and which technological breakthroughs can be expected in chromosome-oriented cancer research Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics was written for everyone with a scientific or clinical interest in cancer, especially how acquired chromosome abnormalities lead to neoplastic transformation. The book teaches how cytogenetic analyses contribute to a better understanding of tumorigenesis, but also how the finding of specific chromosome aberrations can be crucial for the diagnosis, prognosis, and management of cancer patients.

Chromosomal Translocations and Genome Rearrangements in Cancer

Download Chromosomal Translocations and Genome Rearrangements in Cancer PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3319199838
Total Pages : 486 pages
Book Rating : 4.3/5 (191 download)

DOWNLOAD NOW!


Book Synopsis Chromosomal Translocations and Genome Rearrangements in Cancer by : Janet D. Rowley

Download or read book Chromosomal Translocations and Genome Rearrangements in Cancer written by Janet D. Rowley and published by Springer. This book was released on 2015-12-09 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume collates world experts’ insights into the molecular biology of cancer chromosomes, their abnormalities and the subsequent cellular consequences. Exploring themes involving oncogenes, such as by chromosomal translocations, other genome rearrangements and somatic mutations, this book is a review of the field of cancer genetics that presages a new era, as whole genome sequencing becomes more accessible. The work begins with a look at historical themes, such as the analysis of metaphase chromosomes using microscopy and staining techniques, advances in which provided our first broad glimpse into the genetic anatomy of a malignant cell. Readers will learn about the application of DNA molecular cloning techniques in the 1980s, that led to the identification of the genes involved in the Philadelphia and Burkitt's lymphoma chromosomal translocations, solidifying the role of oncogenes and tumour suppressor genes in cancer aetiology via chromosomal alterations and which launched a field in cancer genetics. Subsequent chapters bring the reader up to date by reviewing recent developments in the field, with dedicated sections on leukaemia/lymphoma, sarcomas and epithelial tumours. Contributions feature numerous colour tables and illustrations and this volume will provide a basis for understanding cancer chromosomes for many years to come.

Chromosomes and Cancer

Download Chromosomes and Cancer PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 796 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Chromosomes and Cancer by : James German

Download or read book Chromosomes and Cancer written by James German and published by John Wiley & Sons. This book was released on 1974 with total page 796 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Cytogenetics

Download Cancer Cytogenetics PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118210581
Total Pages : 799 pages
Book Rating : 4.1/5 (182 download)

DOWNLOAD NOW!


Book Synopsis Cancer Cytogenetics by : Sverre Heim

Download or read book Cancer Cytogenetics written by Sverre Heim and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 799 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Cytogenetics, 3rd Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area and incorporates a vast amount of new data from the latest basic and clinical investigations. Edited by two leading experts, and now involving a new panel of international experts, the book offers an authoritative description of neoplastic processes at the chromosomal level of genomic organization. Researchers in cytogenetics, medical and molecular genetics, cellular and molecular biology, cancer research, clinical oncology, and hematology will find this reference both thorough and authoritative.

Chromosome 12 Aberrations in Human Solid Tumors

Download Chromosome 12 Aberrations in Human Solid Tumors PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3662062550
Total Pages : 201 pages
Book Rating : 4.6/5 (62 download)

DOWNLOAD NOW!


Book Synopsis Chromosome 12 Aberrations in Human Solid Tumors by : Jörn Bullerdiek

Download or read book Chromosome 12 Aberrations in Human Solid Tumors written by Jörn Bullerdiek and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers involved in the cytogenetics and molecular genetics of human tumors will welcome this comprehensive overview of the type of aberrations that chromosome 12 presents in human solid tumors. The authors study the implications for a cytogenetic subtyping of the tumors involved and strategies for identifying the molecular changes which underlie the karyotypic alterations. The aberrations of chromosome 12 which the book deals with are very frequent chromosomal alterations in human tumors occuring in frequent benign mesenchymal tumors, such as uterine leiomyomas and lipomas, and in tumors of epithelial origin, such as pleomorphic adenomas of the salivary glands.

The Genetics of Cancer

Download The Genetics of Cancer PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9401106770
Total Pages : 222 pages
Book Rating : 4.4/5 (11 download)

DOWNLOAD NOW!


Book Synopsis The Genetics of Cancer by : B.A. Ponder

Download or read book The Genetics of Cancer written by B.A. Ponder and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.

Chromosomal Instability in Cancer Cells

Download Chromosomal Instability in Cancer Cells PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 331920291X
Total Pages : 228 pages
Book Rating : 4.3/5 (192 download)

DOWNLOAD NOW!


Book Synopsis Chromosomal Instability in Cancer Cells by : B. Michael Ghadimi

Download or read book Chromosomal Instability in Cancer Cells written by B. Michael Ghadimi and published by Springer. This book was released on 2015-09-16 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Recent Results in Cancer Research presents a comprehensive review of current understanding of chromosomal instability in cancer and of strategies to use this information for better treatment of patients with cancer. Cancer is a disease of the chromosomes, and chromosomal instability in cancer disrupts gene function by either inactivating tumor suppressor genes or activating growth-promoting oncogenes. The chromosomal basis for these aberrations is either translocations, which change the integrity of genes, or abnormal numbers of chromosomes, a condition referred to as aneuploidy, which results in abnormal gene expression levels. Such structural or numerical chromosomal aberrations are specific for distinct tumor entities. The degree of chromosomal instability and the degree of intratumor heterogeneity have profound consequences for disease outcome and for therapeutic stratification.

Telomeres and Telomerase in Cancer

Download Telomeres and Telomerase in Cancer PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1603278796
Total Pages : 375 pages
Book Rating : 4.6/5 (32 download)

DOWNLOAD NOW!


Book Synopsis Telomeres and Telomerase in Cancer by : Keiko Hiyama

Download or read book Telomeres and Telomerase in Cancer written by Keiko Hiyama and published by Springer Science & Business Media. This book was released on 2009-03-18 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Telomerase, an enzyme that maintains telomeres and endows eukaryotic cells with immortality, was first discovered in tetrahymena in 1985. In 1990s, it was proven that this enzyme also plays a key role in the infinite proliferation of human cancer cells. Now telomere and telomerase are widely accepted as important factors involved in cancer biology, and as promising diagnostic tools and therapeutic targets. Recently, role of telomerase in “cancer stem cells” has become another attractive story. Until now, there are several good books on telomere and telomerase focusing on biology in ciliates, yeasts, and mouse or basic sciences in human, providing basic scientists or students with updated knowledge.

Chromosomes and Cancer

Download Chromosomes and Cancer PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 398 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Chromosomes and Cancer by : Janet D. Rowley

Download or read book Chromosomes and Cancer written by Janet D. Rowley and published by . This book was released on 1983 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: