Chromatography Its Development And Various Applications

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Chromatography and Its Applications

Author : Sasikumar Dhanarasu
Publisher : BoD – Books on Demand
ISBN 13 : 9535103571
Total Pages : 214 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Chromatography and Its Applications by : Sasikumar Dhanarasu

Download or read book Chromatography and Its Applications written by Sasikumar Dhanarasu and published by BoD – Books on Demand. This book was released on 2012-03-16 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromatography is a powerful separation tool that is used in all branches of science, and is often the only means of separating components from complex mixtures. The Russian botanist Mikhail Tswett coined the term chromatography in 1906. The first analytical use of chromatography was described by James and Martin in 1952, for the use of gas chromatography for the analysis of fatty acid mixtures. A wide range of chromatographic procedures makes use of differences in size, binding affinities, charge, and other properties. Many types of chromatography have been developed. These include Column chromatography, High performance liquid chromatography (HPLC), Gas chromatography, Size exclusion chromatography, Ion exchange chromatography etc. In this book contains more details about the applications of chromatography by various research findings. Each and every topics of this book have included lists of references at the end to provide students and researchers with starting points for independent chromatography explorations. I welcome comments, criticisms, and suggestions from students, faculty and researchers.

Ultra-High Performance Liquid Chromatography and Its Applications

Author : Q. Alan Xu
Publisher : John Wiley & Sons
ISBN 13 : 1118533984
Total Pages : 342 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Ultra-High Performance Liquid Chromatography and Its Applications by : Q. Alan Xu

Download or read book Ultra-High Performance Liquid Chromatography and Its Applications written by Q. Alan Xu and published by John Wiley & Sons. This book was released on 2013-04-01 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explores both the benefits and limitations of new UHPLC technology High performance liquid chromatography (HPLC) has been widely used in analytical chemistry and biochemistry to separate, identify, and quantify compounds for decades. The science of liquid chromatography, however, was revolutionized a few years ago with the advent of ultra-high performance liquid chromatography (UHPLC), which made it possible for researchers to analyze sample compounds with greater speed, resolution, and sensitivity. Ultra-High Performance Liquid Chromatography and Its Applications enables readers to maximize the performance of UHPLC as well as develop UHPLC methods tailored to their particular research needs. Readers familiar with HPLC methods will learn how to transfer these methods to a UHPLC platform and vice versa. In addition, the book explores a variety of UHPLC applications designed to support research in such fields as pharmaceuticals, food safety, clinical medicine, and environmental science. The book begins with discussions of UHPLC method development and method transfer between HPLC and UHPLC platforms. It then examines practical aspects of UHPLC. Next, the book covers: Coupling UHPLC with mass spectrometry Potential of shell particles in fast liquid chromatography Determination of abused drugs in human biological matrices Analyses of isoflavones and flavonoids Therapeutic protein characterization Analysis of illicit drugs The final chapter of the book explores the use of UHPLC in drug metabolism and pharmacokinetics studies for traditional Chinese medicine. With its frank discussions of UHPLC's benefits and limitations, Ultra-High Performance Liquid Chromatography and Its Applications equips analytical scientists with the skills and knowledge needed to take full advantage of this new separation technology.

Handbook of Thin-Layer Chromatography

Author : Joseph Sherma
Publisher : CRC Press
ISBN 13 : 0824748662
Total Pages : 1356 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Handbook of Thin-Layer Chromatography by : Joseph Sherma

Download or read book Handbook of Thin-Layer Chromatography written by Joseph Sherma and published by CRC Press. This book was released on 2003-04-18 with total page 1356 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this third edition, more than 40 renowned authorities introduce and update chapters on the theory, fundamentals, techniques, and instrumentation of thin-layer chromatography (TLC) and high-performance thin-layer chromatography (HPTLC), highlighting the latest procedures and applications of TLC to 19 important compound classes and coverage of TLC applications by compound type. Easily adaptable to industrial scenarios , the Handbook of Thin-Layer Chromatography, Third Edition supports practical research strategies with extensive tables of data, offers numerous figures that illustrate techniques and chromatograms, and includes a glossary as well as a directory of equipment suppliers.

Preparative Chromatography Techniques

Author : K. Hostettmann
Publisher : Springer Science & Business Media
ISBN 13 : 3662036312
Total Pages : 259 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Preparative Chromatography Techniques by : K. Hostettmann

Download or read book Preparative Chromatography Techniques written by K. Hostettmann and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few years, increasing attention has been paid to the search for bioactive compounds from natural sources. The success of plant-derived products such as paclitaxel (Taxol) in tumor therapy or artemisinin in the treatment of malaria has provided the impetus for the introduction of numerous research programmes, especially in Industry. A great deal of effort is being expended in the generation of novel lead molecules of vegetable, marine and microbial origin by the use of high throughput screening protocols. When interesting hits are found, it is essen tial to have methods available for the rapid isolation of target compounds. For this reason, both industry and academia need efficient preparative chromatographic separation techniques and experience in their application. Purified natural products are required for complete spectro scopic identification and full characterization of new compo unds, for biological testing and for the supply of pharmaceuti cals, standards, and starting materials for synthetic work. Obtaining pure products from an extract can be a very long, te dious and expensive undertaking, involving many steps. Sometimes only minute amounts of the desired compounds are at hand and these entities may be labile. Thus it is an advantage to have access to as many different methods as possible in order to aid the isolation process. Although a certain amount of trial and error may be involved, nowadays there is the possibility of devising suitable rapid separation schemes by a judicious choice of the different techniques available.

Forensic Applications of Gas Chromatography

Author : Michelle Groves Carlin
Publisher : CRC Press
ISBN 13 : 1482218933
Total Pages : 189 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Forensic Applications of Gas Chromatography by : Michelle Groves Carlin

Download or read book Forensic Applications of Gas Chromatography written by Michelle Groves Carlin and published by CRC Press. This book was released on 2017-09-11 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several areas of forensic science use the technique of gas chromatography, ranging from fire analysis to the investigation of fraudulent food and perfumes. Covering the essentials of this powerful analytical technique, Forensic Applications of Gas Chromatography explains the theory and shows applications of this knowledge to various realms of foren

Monolithic Chromatography and Its Modern Applications

Author : Perry G. Wang
Publisher : ILM Publications
ISBN 13 : 1906799032
Total Pages : 644 pages
Book Rating : 4.9/5 (67 download)

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Book Synopsis Monolithic Chromatography and Its Modern Applications by : Perry G. Wang

Download or read book Monolithic Chromatography and Its Modern Applications written by Perry G. Wang and published by ILM Publications. This book was released on 2010 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title describes monolithic chromatography and its applications in the analytical field.

Extraction Chromatography

Author :
Publisher : Elsevier
ISBN 13 : 0080858023
Total Pages : 585 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Extraction Chromatography by :

Download or read book Extraction Chromatography written by and published by Elsevier. This book was released on 1975-06-01 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extraction Chromatography

Protein Purification

Author : Jan-Christer Janson
Publisher : John Wiley & Sons
ISBN 13 : 9780471186267
Total Pages : 712 pages
Book Rating : 4.1/5 (862 download)

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Book Synopsis Protein Purification by : Jan-Christer Janson

Download or read book Protein Purification written by Jan-Christer Janson and published by John Wiley & Sons. This book was released on 1998 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a state-of-the-art sourcebook on modern high-resolution biochemical separation techniques for proteins. It contains all the basic theory and principles used in protein chromatography and electrophoresis.

Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development

Author :
Publisher : Elsevier
ISBN 13 : 0323884881
Total Pages : 434 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development by :

Download or read book Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development written by and published by Elsevier. This book was released on 2022-12-02 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development provides a valuable "go-to reference for many difficult-to-solve challenges using pertinent chromatographic theory, first-hand case studies, and examples provided from academic and industry experts. This text also enables professors teaching an analytical instrumental course to introduce and instruct students about one of the most sustainable and powerful separation methods currently available. While the text has broad applicability across industrial sectors, it focuses primarily on application in the pharmaceutical industry. The book is designed to allow readers to align current HPLC/UHPLC capabilities with SFC as an orthogonal tool for project specific methods in the pharmaceutical industry. It highlights where SFC falls on the spectrum of useful chromatographic tools for routine and challenging separative methods. Experienced HPLC users who are interested in developing knowledge in orthogonal separation techniques, as well as newcomers to the field of separation science, will find this text particularly useful. Chapters address where SFC may fit the analytical needs of the pharmaceutical industry and alert the readers as to where the technique will not fit. Readers will gain an understanding of how and where SFC may be applied and adapted more routinely across the pharmaceutical industry as a 'green' way of undertaking separation opportunities and challenges. Areas within the pharmaceutical industry include early drug discovery, process chemistry, and late stage development and manufacturing. - Describes approaches to SFC column and mobile phase selection for method development for both analytical and preparative tasks - Gives practical examples of how analytical SFC enables the monitoring of synthetic reactions including unstable intermediates, chiral and achiral polar reactants and products across small and large modalities - Provides need-focused case studies for pharmaceutical analysts, process chemists, and contract chemistry facilities that can benefit from monitoring or purifying polar intermediates, mutagenic impurities, nitrosamines and other reaction by-products including excipients and metabolites

Principles and Applications of Gas Chromatography in Food Analysis

Author : Michael H. Gordon
Publisher : Springer Science & Business Media
ISBN 13 : 1461306817
Total Pages : 371 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Principles and Applications of Gas Chromatography in Food Analysis by : Michael H. Gordon

Download or read book Principles and Applications of Gas Chromatography in Food Analysis written by Michael H. Gordon and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: The food analyst plays an important role in modern society. Stricter control over additives in food and concern about the effects of contamination of food by industrial and agricultural chemicals are among the developments which are leading to an increasing emphasis on detailed and accurate analysis of food. However. analysis of food is required for many reasons, including detection of toxic components, monitoring legislation, detecting adulteration, formulation of controlled diets, controlling formulation during product development and detecting changes in food during storage and processing. Foods comprise a complex mixture of components and food analysis requires efficient methods of separation with high sensitivity or specificity of detection. Although many food components are involatile or thermally labile and therefore not suitable for analysis by gas chromatography, other components are volatile and this technique is the preferred analytical method. Developments in methods of derivati zation, injector design and column technology have also extended the applicability of gas chromatography to the analysis of relatively involatile compounds.

Preparative Chromatography

Author : H. Schmidt-Traub
Publisher : John Wiley & Sons
ISBN 13 : 3527649301
Total Pages : 545 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Preparative Chromatography by : H. Schmidt-Traub

Download or read book Preparative Chromatography written by H. Schmidt-Traub and published by John Wiley & Sons. This book was released on 2012-09-27 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and substantially extended to reflect the developments in this fast-changing field. It retains the interdisciplinary approach that elegantly combines the chemistry and engineering involved to describe the conception and improvement of chromatographic processes. It also covers recent advances in preparative chromatographic processes for the separation of "smaller" molecules using standard laboratory equipment as well as the detailed conception of industrial chemical plants. The increase in biopharmaceutical substances is reflected by new and revised chapters on different modifications of continuous chromatography as well as ion-exchange chromatography and other separation principles widely used in biochromatography. Following an introductory section on the history of chromatography, the current state of research and the design of chromatographic processes, the book goes on to define the general terminology. There then follow sections on stationary phases, selection of chromatographic systems and process concepts. A completely new chapter deals with engineering and operation of chromatographic equipment. Final chapters on modeling and determination of model parameters as well as model based design, optimization and control of preparative chromatographic processes allow for optimal selection of chromatographic processes. Essential for chemists and chemical engineers in the chemical, pharmaceutical, and food industries.

Liquid Chromatography

Author : Salvatore Fanali
Publisher : Elsevier
ISBN 13 : 0128093447
Total Pages : 840 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Liquid Chromatography by : Salvatore Fanali

Download or read book Liquid Chromatography written by Salvatore Fanali and published by Elsevier. This book was released on 2017-06-23 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liquid Chromatography: Applications, Second Edition,is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their knowledge of the wide variety of applications in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more. This second edition addresses these new developments with updated chapters from the most expert researchers in the field. - Emphasizes the integration of chromatographic methods and sample preparation - Explains how liquid chromatography is used in different industrial sectors - Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical) - Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making

Applications of Ion Chromatography for Pharmaceutical and Biological Products

Author : Lokesh Bhattacharyya
Publisher : John Wiley & Sons
ISBN 13 : 0470467096
Total Pages : 484 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Applications of Ion Chromatography for Pharmaceutical and Biological Products by : Lokesh Bhattacharyya

Download or read book Applications of Ion Chromatography for Pharmaceutical and Biological Products written by Lokesh Bhattacharyya and published by John Wiley & Sons. This book was released on 2012-03-27 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive source of information on the application of ion chromatography (IC) in the analysis of pharmaceutical drugs and biologicals. This book, with contributors from academia, pharma, the biotech industry, and instrument manufacturing, presents the different perspectives, experience, and expertise of the thought leaders of IC in a comprehensive manner. It explores potential IC applications in different aspects of product development and quality control testing. In addition, an appendix section gives information on critical physical and chromatographic parameters related to IC and information on current manufacturers of IC systems, columns, and other components.

Introduction to Modern Liquid Chromatography

Author : Lloyd R. Snyder
Publisher : John Wiley & Sons
ISBN 13 : 1118210395
Total Pages : 831 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Introduction to Modern Liquid Chromatography by : Lloyd R. Snyder

Download or read book Introduction to Modern Liquid Chromatography written by Lloyd R. Snyder and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 831 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest edition of the authoritative reference to HPLC High-performance liquid chromatography (HPLC) is today the leading technique for chemical analysis and related applications, with an ability to separate, analyze, and/or purify virtually any sample. Snyder and Kirkland's Introduction to Modern Liquid Chromatography has long represented the premier reference to HPLC. This Third Edition, with John Dolan as added coauthor, addresses important improvements in columns and equipment, as well as major advances in our understanding of HPLC separation, our ability to solve problems that were troublesome in the past, and the application of HPLC for new kinds of samples. This carefully considered Third Edition maintains the strengths of the previous edition while significantly modifying its organization in light of recent research and experience. The text begins by introducing the reader to HPLC, its use in relation to other modern separation techniques, and its history, then leads into such specific topics as: The basis of HPLC separation and the general effects of different experimental conditions Equipment and detection The column—the "heart" of the HPLC system Reversed-phase separation, normal-phase chromatography, gradient elution, two-dimensional separation, and other techniques Computer simulation, qualitative and quantitative analysis, and method validation and quality control The separation of large molecules, including both biological and synthetic polymers Chiral separations, preparative separations, and sample preparation Systematic development of HPLC separations—new to this edition Troubleshooting tricks, techniques, and case studies for both equipment and chromatograms Designed to fulfill the needs of the full range of HPLC users, from novices to experts, Introduction to Modern Liquid Chromatography, Third Edition offers the most up-to-date, comprehensive, and accessible survey of HPLC methods and applications available.

Chromatography in Food Science and Technology

Author : Tibor Cserhati
Publisher : CRC Press
ISBN 13 : 1000117243
Total Pages : 569 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Chromatography in Food Science and Technology by : Tibor Cserhati

Download or read book Chromatography in Food Science and Technology written by Tibor Cserhati and published by CRC Press. This book was released on 2020-08-26 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: oCompilation and evaluation of the newest applications of chromatography for food science and technology oEnumeration of chromatographic methods and critical discussion of results This book presents a unique collection of up-to-date chromatographic methods for the separation and quantitative determination of carbohydrates, lipids, proteins, peptides, amino acids, vitamins, aroma and flavor compounds in a wide variety of foods and food products. Chromatography in Food Science and Technology presents a concise evaluation of existing chromatographic methods used for many food and food product macro and microcomponents. Chromatographic methods are compiled according to the character of the food components to be separated. The book's chapters deal separately with the different classes of food components, presenting both gas and liquid chromatographic methods used for their determination, and discussing the advantages and disadvantages of each. Unlike other references, Chromatography in Food Science and Technology is entirely devoted to the use of chromatography for food analysis, and focuses on practical, food-related examples. It treats the theoretical aspects of chromatography briefly, to the degree that the information helps the use and development of new analytical methods for the separation of any kind of food components.

Multidimensional Liquid Chromatography

Author : Steven A. Cohen
Publisher : Wiley-Interscience
ISBN 13 : 9780471738473
Total Pages : 0 pages
Book Rating : 4.7/5 (384 download)

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Book Synopsis Multidimensional Liquid Chromatography by : Steven A. Cohen

Download or read book Multidimensional Liquid Chromatography written by Steven A. Cohen and published by Wiley-Interscience. This book was released on 2008-04-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multidimensional Liquid Chromatography (MDLC) is a very powerful separation technique for analyzing exceptionally complex samples in one step. This authoritative reference presents a number of recent contributions that help define the current art and science of MDLC. Topics covered include instrumentation, theory, methods development, and applications of MDLC in the life sciences and in industrial chemistry. With the information to help you perform very difficult separations of complex samples, this reference includes chapters contributed by leading experts or teams of experts.

Forensic Applications of High Performance Liquid Chromatography

Author : Shirley Bayne
Publisher : CRC Press
ISBN 13 : 1439882592
Total Pages : 278 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Forensic Applications of High Performance Liquid Chromatography by : Shirley Bayne

Download or read book Forensic Applications of High Performance Liquid Chromatography written by Shirley Bayne and published by CRC Press. This book was released on 2017-07-27 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromatography has many roles in forensic science, ranging from toxicology to environmental analysis. In particular, high-performance liquid chromatography (HPLC) is a primary method of analysis in many types of laboratories. Maintaining a balance between practical solutions and the theoretical considerations involved in HPLC analysis, Forensic App