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Author :
Publisher : Am Cncl on Science, Health
ISBN 13 :
Total Pages : 16 pages
Book Rating : 4./5 ( download)
Download or read book Chemoprevention of Breast Cancer written by and published by Am Cncl on Science, Health. This book was released on with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Robert C. Bast, Jr.
Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2004 pages
Book Rating : 4.1/5 (19 download)
Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author : K. I. Bland
Publisher : Saunders
ISBN 13 :
Total Pages : 822 pages
Book Rating : 4.0/5 (919 download)
Download or read book The Breast written by K. I. Bland and published by Saunders. This book was released on 2009 with total page 822 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering the most comprehensive, up-to-date information on the diagnosis and management of, and rehabilitation following, surgery for benign and malignant diseases of the breast, this surgical reference is now in a new edition available in both print and online for easy, convenient access to the absolute latest advances.
Author : Seigo Nakamura
Publisher : Springer Nature
ISBN 13 : 9811645213
Total Pages : 324 pages
Book Rating : 4.8/5 (116 download)
Download or read book Hereditary Breast and Ovarian Cancer written by Seigo Nakamura and published by Springer Nature. This book was released on 2021-10-20 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly informative and clearly written book presents the basic science and the latest data on hereditary breast and ovarian cancer (HBOC) to provide an up-to-date and holistic overview of the disease. It starts off by presenting the molecular mechanisms, genetic testing and counseling, and variants of unknown significance (VUS) to help readers understand the contemporary interpretation of the disease. Further chapters focus on the surveillance, diagnosis and treatment, including chemoprevention, risk reduction and drug development based on molecular mechanisms. It also includes a chapter on the latest findings from the HBOC database, ethical issues and the parp inhibitors, and discusses innovative thinking to manage and understand the disease. Hereditary Breast and Ovarian Cancer - Molecular Mechanism and Clinical Practice offers breast surgeons, medical oncologists, gynecological oncologists and genetic counselors a comprehensive overview of the disease. Providing insights into recent scientific findings and further avenues for investigation, it is also a thought-provoking and informative read for researchers and scholars.
Author : Lida A. Mina
Publisher : Springer
ISBN 13 : 3319194372
Total Pages : 108 pages
Book Rating : 4.3/5 (191 download)
Download or read book Breast Cancer Prevention and Treatment written by Lida A. Mina and published by Springer. This book was released on 2016-06-02 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uniquely designed for oncologists and general practitioners, this book offers clinicians comprehensive guidelines when dealing with women at high risk for breast cancer. Written by experts in the field on the cutting edge of this research, the following questions will be answered for the reader by the end of the book: · Who is at elevated risk for breast cancer? · Who should be genetically screened? · When and how often should we obtain imaging? · What type of imaging is adequate? · What medications are available for prevention? · When is surgical intervention appropriate? · What lifestyle changes should be implemented to prevent this disaster? With one in eight women likely to contract breast cancer in her lifetime, the significance of identifying and managing the high-risk patient is evident. Breakthroughs in the identification of genes associated with breast carcinoma, particularly BRCA1 and 2, as well as other risk factors, influence not only how patients are screened, but also how they are treated. Breast Cancer Prevention and Treatment provides a guided approach to prevention of breast cancer in women at elevated risk for this malignancy.
Author : William J. Gradishar
Publisher : Springer Science & Business Media
ISBN 13 : 9780792378907
Total Pages : 230 pages
Book Rating : 4.3/5 (789 download)
Download or read book Advances in Breast Cancer Management, 2nd edition written by William J. Gradishar and published by Springer Science & Business Media. This book was released on 2000-08-31 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: The optimal management of breast cancer patients relies on the expertise of a team of medical specialists including radiologists, surgeons, radiation therapists and medical oncologists. Much of the progress in breast cancer management made over the last several years reflects the translation of observations made in the laboratory to the clinic. Critically evaluating the impact of new treatment approaches relies on a commitment to well-designed clinical trials. In this volume, Advances in Breast Cancer Management, a renowned group of breast cancer experts have been asked to provide their perspective on management issues that directly effect patients on a day-to-day basis. Dr. Melody Cobleigh discusses the consequences of estrogen deprivation and the ways of ameliorating secondary symptoms and the potential long-term morbidity. Drs. Haigh and Guiliano review the sentinel lymph node biopsy technique including results from their extensive experience. Dr. Abram Recht places into perspective the potential benefit of post-mastectomy radiotherapy and reviews recent trials that address this issue. Dr. Dennis Slamon takes from us from the laboratory to the clinic in explaining the development of Herceptin as a paradigm for therapy targeted to specific molecular characteristics of breast cancer tumor cells. Drs. Nieto, Shpall, Crump and Pritchard offer different perspectives on the future of high-dose chemotherapy with stem cell transplantation as a treatment for breast cancer patients. Drs.
Author : Guilherme Novita
Publisher : Springer Nature
ISBN 13 : 3030136361
Total Pages : 604 pages
Book Rating : 4.0/5 (31 download)
Download or read book Breast Diseases written by Guilherme Novita and published by Springer Nature. This book was released on 2019-10-08 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed in a small-format for practical reading and point-of-care setting use, this work presents the most up-to-date concepts on breast diseases. The main objective of this book is to propagate current knowledge of the most frequent breast diseases, being a quick reference, evidence-based manual covering the major clinical scenarios in mastology. The essence of the work can be summarized in the following sentence: "access to maximum content in the least amount of time.” The book contains data that will allow readers to understand and treat patients with different complaints and diseases. Each chapter presents a flow chart and a summary of the five major publications on the subject. This is unique in comparison with other books in this medical specialty. Developed by a team of international expert specialists who deal with breast pathologies on a daily basis, the book also includes additional contributions from experienced, renowned professionals in interdisciplinary specialties related to the main area. This book will be of interest to physicians who deal with breast diseases and wish to improve their knowledge through exposure to state-of-the-art data and best practices advice. It is also directed to medical students and residents in training within mastology. (This title was originally published in Portuguese by the Brazilian publisher Atheneu in 2011 and has sold very well and gone into a third edition, published in 2017. The Editors have all English language rights, detailed in the attached contract, although it is in Portuguese).
Download or read book Chemoprevention of Breast Cancer written by and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: CONTEXT: Breast cancer is an important cause of morbidity and mortality among women in the United States. Secondary prevention by screening is only moderately effective. Primary prevention by chemoprevention may be an important strategy. OBJECTIVE: To examine the evidence about the benefits and harms of breast cancer chemoprevention for pre- and postmenopausal women for the U.S. Preventive Services Task Force. DATA SOURCES: We identified English-language articles on breast cancer chemoprevention from comprehensive searches of the MEDLINE database from 1966 through January 2000. We used systematic reviews, hand searching of relevant articles, and extensive peer review to identify important articles and assure completeness. STUDY SELECTION: We included all randomized controlled trials of chemoprevention agents of at least one year's duration among women at low to high risk for breast cancer that measured clinical endpoints of breast cancer incidence and harms of treatment. We also included, as background, other studies that reported benefits and harms of the chemopreventive agents. DATA EXTRACTION: We extracted the following data from the four included articles: demographic and breast cancer risk details about patients, inclusion criteria, study design and randomization, duration, interventions, and outcome measures. We evaluated the internal and external validity of each article. We judged the overall quality of evidence on aggregate internal and external validity and coherence of the results. DATA SYNTHESIS: Strong, direct evidence shows that tamoxifen reduces by approximately half the incidence of invasive and noninvasive breast cancer in pre- and postmenopausal women at high risk for breast cancer. Similarly, evidence from one study suggests that raloxifene reduces by the same amount the incidence of invasive breast cancer in postmenopausal women at low to average risk for breast cancer. Raloxifene also reduces the risk of vertebral fractures in postmenopausal women with osteoporosis. Both drugs are associated with an increased risk of venous thromboembolic disease (deep vein thrombosis and pulmonary embolism); tamoxifen is also associated with an increased risk of endometrial cancer. The balance between benefits and harms varies among subgroups of women, depending on age, predicted risk of breast cancer, and hysterectomy status. CONCLUSIONS: Tamoxifen and raloxifene reduce the incidence of breast cancer in women over a wide range of ages and levels of breast cancer risk. Both drugs may also have other benefits, but they may cause harm in otherwise healthy women who take them for prophylaxis.
Author : Raymond C. Bergan
Publisher : Springer
ISBN 13 : 9781461356639
Total Pages : 0 pages
Book Rating : 4.3/5 (566 download)
Download or read book Cancer Chemoprevention written by Raymond C. Bergan and published by Springer. This book was released on 2012-10-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume offers a broad overview of topics related to cancer chemoprevention. It provides a review of topics ranging from basic research arenas to clinical trial design, implementation, and interpretation. It covers all key areas necessary for understanding the field of cancer chemoprevention for the interested reader, for individuals wishing to enter this area of investigation, and for individuals seeking guidance in particular areas of research, relating to agent identification, basic science investigations and clinical trials. The genesis of this book is based on the fact that cancer chemoprevention is a relatively new and rapidly evolving field spanning a wide array of disciplines, and forces researchers to address difficult and complex questions whose answers are not readily available. Cancer Chemoprevention provides a ready resource whose importance and intent lie in its ability to gather and solidify disparate data to explicitly outline areas of difficulty and to highlight future areas of important development. It provides broad outlines for current, ongoing and future directions in this area with various target organ sites, written by experts in their respective fields, whose primary research focuses upon that individual field.
Author : William C.S. Cho
Publisher : Springer Science & Business Media
ISBN 13 : 940076443X
Total Pages : 323 pages
Book Rating : 4.4/5 (7 download)
Download or read book Cancer Chemoprevention and Treatment by Diet Therapy written by William C.S. Cho and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments’ side effects. In the past, clinical data showed that some complementary and alternative medicine (CAM) possessed anticancer abilities, but some clinicians and scientists have queried about the scientific validity of CAM due to the lack of scientific evidence. There is great demand in the knowledge gap to explore the scientific and evidence-based knowledge of CAM in the anticancer field. With this aim, a book series is needed to structurally deliver the knowledge to readers. Throughout the past few years, the cancer chemopreventive potencies and treatment effects of a number of natural dietary agents present in different food sources have been evaluated by various experiments. Some of them have progressed to early clinical trials. This volume is a specialized book presenting the research evidence relevant to the use of specific diet therapy in cancer chemoprevention and treatment. We begin with lessons learned from dietary resveratrol as an effective agent with anticancer properties against malignancies, followed examples of flavonoids from fruits and vegetables in the prevention and treatment of cancer. Evidence for the beneficial influence of diet enriched with flax seed oil and green tea on cancer will be reviewed. Soy food intake may enhance the effects on anticancer treatment for breast cancer, whereas lycopene-rich foods may possess chemopreventive efficacy. There are also discussions on the contribution of the cancer preventive effects of the antioxidant-rich foods and Mediterranean diet. In addition, the modulation of proteasome pathways by nutraceuticals is highlighted. Finally, we close the book with a discussion on the attenuation of cell survival signaling by bioactive phytochemicals in the prevention and therapy cancer.
Author : Philipp Y. Maximov
Publisher : Springer Science & Business Media
ISBN 13 : 3034806647
Total Pages : 218 pages
Book Rating : 4.0/5 (348 download)
Download or read book Tamoxifen written by Philipp Y. Maximov and published by Springer Science & Business Media. This book was released on 2013-07-23 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tamoxifen is a pioneering medicine for the treatment and prevention of breast cancer. It is the first drug targeted therapy in cancer to be successful. Tamoxifen targets the tumor estrogen receptor. The therapy is known to have saved the lives of millions of women over the past 40 years. This monograph, written by V. Craig Jordan - known as the “father of tamoxifen” - and his Tamoxifen Team at the Georgetown University Washington DC, illustrates the journey of this milestone in medicine. It includes a personal interview with V. Craig Jordan about his four decades of discovery in breast cancer research and treatment. V. Craig Jordan was there for the birth of tamoxifen as he is credited for reinventing a “failed morning after contraceptive” to become the “gold standard” for the treatment of breast cancer. He contributed to every aspect of tamoxifen application in therapeutics and all aspects of tamoxifen’s pharmacology. He discovered the selective estrogen receptor modulators (SERMs) and explored the new biology of estrogen-induced apoptosis.
Author : Gary J. Kelloff
Publisher : Springer Science & Business Media
ISBN 13 : 159259767X
Total Pages : 998 pages
Book Rating : 4.5/5 (925 download)
Download or read book Cancer Chemoprevention written by Gary J. Kelloff and published by Springer Science & Business Media. This book was released on 2004-06-04 with total page 998 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accompanying CD-ROM in pocket at end of v. 2 contains a compact e-book version of v. 2.
Author : Edward R. Sauter
Publisher : Springer Science & Business Media
ISBN 13 : 0387875832
Total Pages : 251 pages
Book Rating : 4.3/5 (878 download)
Download or read book Breast Cancer Risk Reduction and Early Detection written by Edward R. Sauter and published by Springer Science & Business Media. This book was released on 2010-01-22 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: While many comprehensive texts have been written on the treatment of breast cancer, the most common cancer among women, there are relatively few which cover in depth the prevention and early detection of the disease. The goal of this work is to present what experts in the ?eld feel is the current knowledge and future direction of breast cancer prevention and early detection. We begin Part I of the book with a review of risk factors, both genetic and environmental. We next review progress in the use of chemoprevention. Notably, chemoprevention risk reduction studies have led to FDA approval of two medications which measurably reduce disease incidence among women at increased risk, although with some risk of treatment related side effects. Newer agents in the pipeline, which may also reduce risk among normal risk women, are also discussed. Surgical risk reducing strategies complete the section on prevention, including both the bene?ts and downsides to this more aggressive approach. Even with aggressive prevention strategies, some women will develop breast cancer. For these women, early detection is critical to minimize disease spread and maximize long term survival. Part II of this book reviews current and upcoming approaches to early detection. Imaging strategies, including mammography, breast ultrasound, MRI, and PET imaging are reviewed. The potential for molecular tumor targeting to detect disease prior to the formation of a mass visible by anatomic imaging is presented.
Author : Daniel W. Nixon
Publisher : CRC Press
ISBN 13 : 9780849368509
Total Pages : 160 pages
Book Rating : 4.3/5 (685 download)
Download or read book Chemoprevention of Cancer written by Daniel W. Nixon and published by CRC Press. This book was released on 1994-11-08 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemoprevention of Cancer guides you through the exciting new field of cancer chemoprevention. It covers epidemiology, known chemopreventive compounds, development of new chemopreventive agents, specific examples of preventive agents and their mechanisms of action, and current prevention clinical trials.
Author : Gillian M. Newstead
Publisher : Thieme
ISBN 13 : 162623468X
Total Pages : 728 pages
Book Rating : 4.6/5 (262 download)
Download or read book Breast MRI Interpretation written by Gillian M. Newstead and published by Thieme. This book was released on 2021-01-06 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: State-of-the-art resource details effective breast MRI techniques for improved screening and diagnosis Magnetic resonance imaging (MRI) of the breast has evolved into an important breast cancer screening tool and major advance in women's health. Breast MRI is currently the most sensitive detection technique for both non-invasive and invasive cancers and follow-up in women with a new breast cancer diagnosis. It is increasingly becoming the go-to imaging method for screening women at high and intermediate risk of breast cancer and those with dense breast tissue on mammography. Yet despite its reliability and growing use, many radiologists lack the expertise to accurately perform breast MR image interpretation. Breast MRI Interpretation: Text and Case Analysis for Screening and Diagnosis by Gillian M. Newstead reflects insights and expertise from one of the leading authorities on breast imaging. The book is a highly practical reference on evaluation and interpretation of breast MR imaging, with discussion of the modality as a screening and diagnostic tool. Topics include image acquisition and interpretation, clinical implementation, managing findings, and overcoming problems. Key Highlights About 3,000 illustrations from the University of Chicago including single selected images, side-by-side images at different time points and acquisition parameters, and 3-D images enhance understanding of breast imaging Discussion of advanced acquisition techniques and future potential applications including non-contrast imaging, quantitative dynamic imaging, and artificial intelligence using advanced computer analytic methods This remarkable resource streamlines the breast MRI process, enabling radiologists to incorporate this imaging modality into practice, conduct screening and diagnostic exams more efficaciously, and interpret findings accurately.
Author : John M. Pezzuto
Publisher : Springer Nature
ISBN 13 : 3030398552
Total Pages : 639 pages
Book Rating : 4.0/5 (33 download)
Download or read book Natural Products for Cancer Chemoprevention written by John M. Pezzuto and published by Springer Nature. This book was released on 2020-04-03 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the efficacy of various naturally occurring chemopreventive agents in preventing or delaying cancer. It focuses on the holistic chemopreventive concept, demonstrating the relevant response is the combined effect of a series of compounds that alone have been shown to have some effect in different experimental models. Written by leading experts in the field, the contributions provide details of research on various chemopreventive agents. Offering insights into the unique molecular targets and mechanisms, safety issues, molecular efficacy, and occurrence in nature of these compounds, the book is a valuable resource for all scientists working in biomedicine, and specifically in cancer research.
Author : Goutam Brahmachari
Publisher : Elsevier
ISBN 13 : 0128212780
Total Pages : 386 pages
Book Rating : 4.1/5 (282 download)
Download or read book Discovery and Development of Anti-Breast Cancer Agents from Natural Products written by Goutam Brahmachari and published by Elsevier. This book was released on 2021-06-24 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discovery and Development of Anti-Breast Cancer Agents from Natural Products presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations. This volume in the Natural Products Drug Discovery series focuses on molecules of natural origin and their synthetic analogs that show promising potential to act as anti-breast cancer and chemotherapeutic agents. Combining foundational background information on cancer mechanisms with details of medicinal structures from natural products, this volume compiles the latest developments from across interdisciplinary fields.Discovery and Development of Anti-Breast Cancer Agents from Natural Products will serve as a valuable resource for researchers working to discover promising leads for the development of novel pharmaceuticals for breast cancer, highlighting a number of key structures from natural products and exploring possible future developments in the area. - Highlights active agents from natural sources for development as novel anti-cancer agents - Features contributions from active researchers and leading experts working in the field - Includes foundational background information on both breast cancer mechanisms and natural product structures to support researchers from different disciplines
