Patents for Chemicals, Pharmaceuticals and Biotechnology

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Author :
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 552 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Patents for Chemicals, Pharmaceuticals and Biotechnology by : Philip W. Grubb

Download or read book Patents for Chemicals, Pharmaceuticals and Biotechnology written by Philip W. Grubb and published by Oxford University Press, USA. This book was released on 2004 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Previous editions, 1st and 2nd, published under titles : 1st (1982) Patents for chemists ; 2nd (1986) Patents in chemistry and biotechnology ; 3rd edition published in 1999.

Chemical Engineering in the Pharmaceutical Industry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 111928550X
Total Pages : 1435 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Chemical Engineering in the Pharmaceutical Industry by : Mary T. am Ende

Download or read book Chemical Engineering in the Pharmaceutical Industry written by Mary T. am Ende and published by John Wiley & Sons. This book was released on 2019-04-08 with total page 1435 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products.

Chemical Engineering in the Pharmaceutical Industry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119285860
Total Pages : 1172 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Chemical Engineering in the Pharmaceutical Industry by : David J. am Ende

Download or read book Chemical Engineering in the Pharmaceutical Industry written by David J. am Ende and published by John Wiley & Sons. This book was released on 2019-04-23 with total page 1172 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the development and manufacturing of pharmaceutical products written for professionals in the industry, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry is a practical book that highlights chemistry and chemical engineering. The book’s regulatory quality strategies target the development and manufacturing of pharmaceutically active ingredients of pharmaceutical products. The expanded second edition contains revised content with many new case studies and additional example calculations that are of interest to chemical engineers. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The active pharmaceutical ingredients book puts the focus on the chemistry, chemical engineering, and unit operations specific to development and manufacturing of the active ingredients of the pharmaceutical product. The drug substance operations section includes information on chemical reactions, mixing, distillations, extractions, crystallizations, filtration, drying, and wet and dry milling. In addition, the book includes many applications of process modeling and modern software tools that are geared toward batch-scale and continuous drug substance pharmaceutical operations. This updated second edition: Contains 30new chapters or revised chapters specific to API, covering topics including: manufacturing quality by design, computational approaches, continuous manufacturing, crystallization and final form, process safety Expanded topics of scale-up, continuous processing, applications of thermodynamics and thermodynamic modeling, filtration and drying Presents updated and expanded example calculations Includes contributions from noted experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduate students, and professionals in the field of pharmaceutical sciences and manufacturing, the second edition of Chemical Engineering in the Pharmaceutical Industryf ocuses on the development and chemical engineering as well as operations specific to the design, formulation, and manufacture of drug substance and products.

Merck's Index

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Author :
Publisher :
ISBN 13 :
Total Pages : 496 pages
Book Rating : 4.6/5 (546 download)

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Book Synopsis Merck's Index by :

Download or read book Merck's Index written by and published by . This book was released on 1907 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chemical Engineering in the Pharmaceutical Industry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118088107
Total Pages : 1431 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Chemical Engineering in the Pharmaceutical Industry by : David J. am Ende

Download or read book Chemical Engineering in the Pharmaceutical Industry written by David J. am Ende and published by John Wiley & Sons. This book was released on 2011-03-10 with total page 1431 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with various unique elements in the drug development process within chemical engineering science and pharmaceutical R&D. The book is intended to be used as a professional reference and potentially as a text book reference in pharmaceutical engineering and pharmaceutical sciences. Many of the experimental methods related to pharmaceutical process development are learned on the job. This book is intended to provide many of those important concepts that R&D Engineers and manufacturing Engineers should know and be familiar if they are going to be successful in the Pharmaceutical Industry. These include basic analytics for quantitation of reaction components– often skipped in ChE Reaction Engineering and kinetics books. In addition Chemical Engineering in the Pharmaceutical Industry introduces contemporary methods of data analysis for kinetic modeling and extends these concepts into Quality by Design strategies for regulatory filings. For the current professionals, in-silico process modeling tools that streamline experimental screening approaches is also new and presented here. Continuous flow processing, although mainstream for ChE, is unique in this context given the range of scales and the complex economics associated with transforming existing batch-plant capacity. The book will be split into four distinct yet related parts. These parts will address the fundamentals of analytical techniques for engineers, thermodynamic modeling, and finally provides an appendix with common engineering tools and examples of their applications.

The Life-Cycle of Pharmaceuticals in the Environment

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Author :
Publisher : Elsevier
ISBN 13 : 190881845X
Total Pages : 272 pages
Book Rating : 4.9/5 (88 download)

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Book Synopsis The Life-Cycle of Pharmaceuticals in the Environment by : B.M. Peake

Download or read book The Life-Cycle of Pharmaceuticals in the Environment written by B.M. Peake and published by Elsevier. This book was released on 2015-11-13 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Life-Cycle of Pharmaceuticals in the Environment identifies pathways of entry of pharmaceuticals into the environment, beginning with the role of global prescribing and disposal practices. The book then discusses typical levels of common pharmaceuticals and how they can be determined in natural waters such as raw and treated sewage, and in potable water. In addition, sections examine methods currently available to degrade pharmaceuticals in natural waters and some of their ecotoxicological impacts, along with future considerations and the growing concept of product stewardship. - Encompasses the full lifecycle of common pharmaceuticals, from prescription and dispensing practices to their occurrence in a range of different types of natural waters and their environmental impact - Explores the role of the healthcare system and its affect on users - Beneficial for environmental engineers involved in the design and operation of appropriate degradation technologies of the pharmaceutical prescription and disposal practices

Fundamentals of Industrial Chemistry

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Publisher : John Wiley & Sons
ISBN 13 : 1118708660
Total Pages : 266 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Fundamentals of Industrial Chemistry by : John A. Tyrell

Download or read book Fundamentals of Industrial Chemistry written by John A. Tyrell and published by John Wiley & Sons. This book was released on 2014-04-28 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the connectivity between major chemicals, showing how a chemical is made along with why and some of the business considerations. The book helps smooth a student’s transition to industry and assists current professionals who need to understand the larger picture of industrial chemistry principles and practices. The book: Addresses a wide scope of content, emphasizing the business and polymer / pharmaceutical / agricultural aspects of industrial chemistry Covers patenting, experimental design, and systematic optimization of experiments Written by an author with extensive industrial experience but who is now a university professor, making him uniquely positioned to present this material Has problems at the end of chapters and a separate solution manual available for adopting professors Puts chemical industry topics in context and ties together many of the principles chemistry majors learn across more specific courses

Preparative Chromatography

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527649301
Total Pages : 545 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Preparative Chromatography by : H. Schmidt-Traub

Download or read book Preparative Chromatography written by H. Schmidt-Traub and published by John Wiley & Sons. This book was released on 2012-09-27 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and substantially extended to reflect the developments in this fast-changing field. It retains the interdisciplinary approach that elegantly combines the chemistry and engineering involved to describe the conception and improvement of chromatographic processes. It also covers recent advances in preparative chromatographic processes for the separation of "smaller" molecules using standard laboratory equipment as well as the detailed conception of industrial chemical plants. The increase in biopharmaceutical substances is reflected by new and revised chapters on different modifications of continuous chromatography as well as ion-exchange chromatography and other separation principles widely used in biochromatography. Following an introductory section on the history of chromatography, the current state of research and the design of chromatographic processes, the book goes on to define the general terminology. There then follow sections on stationary phases, selection of chromatographic systems and process concepts. A completely new chapter deals with engineering and operation of chromatographic equipment. Final chapters on modeling and determination of model parameters as well as model based design, optimization and control of preparative chromatographic processes allow for optimal selection of chromatographic processes. Essential for chemists and chemical engineers in the chemical, pharmaceutical, and food industries.

Research and Development Management in the Chemical and Pharmaceutical Industry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527606343
Total Pages : 280 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Research and Development Management in the Chemical and Pharmaceutical Industry by : Peter Bamfield

Download or read book Research and Development Management in the Chemical and Pharmaceutical Industry written by Peter Bamfield and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mastering management skills is hard to achieve by newcomers starting their careers in the chemical industry. The message coming from there is that good chemists swiftly have to become good managers if they are to survive and progress in today's competitive climate. This book is designed to help guide younger R & D chemists to ways in which they can quickly evolve skills which are built around three factors - people, knowledge and time. It covers the management of scientific personnel, management within a variety of R & D organisational structures, creating a climate of innovation, the management of projects including the time management and communication aspects of the job. The author, Peter Bamfield, is now working as a consultant. Due to his long experience in the chemical industry, he was elected President of the Royal Society of Chemistry's Industrial Affairs Division. This second edition of the book has been revised and updated to take recent global developments and restructuring in the chemical industry into account, as well as the rising importance of information technology in management.

Pharmaceutical Process Development

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1849733074
Total Pages : 375 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Pharmaceutical Process Development by : John Blacker

Download or read book Pharmaceutical Process Development written by John Blacker and published by Royal Society of Chemistry. This book was released on 2011-08-17 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical process research and development is an exacting, multidisciplinary effort but a somewhat neglected discipline in the chemical curriculum. This book presents an overview of the many facets of process development and how recent advances in synthetic organic chemistry, process technology and chemical engineering have impacted on the manufacture of pharmaceuticals. In 15 concise chapters the book covers such diverse subjects as route selection and economics, the interface with medicinal chemistry, the impact of green chemistry, safety, the crucial role of physical organic measurements in gaining a deeper understanding of chemical behaviour, the role of the analyst, new tools and innovations in reactor design, purification and separation, solid state chemistry and its role in formulation. The book ends with an assessment of future trends and challenges. The book provides a valuable overview of: both early and late stage chemical development, how safe and scaleable synthetic routes are designed, selected and developed, the importance of the chemical engineering, analytical and manufacturing interfaces, the key enabling technologies, including catalysis and biocatalysis, the importance of the green chemical perspective and solid form issues. The book, written and edited by experts in the field, is a contemporary, holistic treatise, with a logical sequence for process development and mini-case histories within the chapters to bring alive different aspects of the process. It is completely pharmaceutical themed, encompassing all essential aspects, from route and reagent selection to manufacture of the active compound. The book is aimed at both graduates and postgraduates interested in a career in the pharmaceutical industry. It informs them about the breadth of the work carried out in chemical research and development departments, and gives them a feel for the challenges involved in the job. The book is also of value to academics who often understand the drug discovery arena, but have far less appreciation of the drug development area, and are thus unable to advise their students about the relative merits of careers in chemical development versus discovery.

HPLC Method Development for Pharmaceuticals

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Author :
Publisher : Elsevier
ISBN 13 : 0080554199
Total Pages : 533 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis HPLC Method Development for Pharmaceuticals by : Satinder Ahuja

Download or read book HPLC Method Development for Pharmaceuticals written by Satinder Ahuja and published by Elsevier. This book was released on 2011-09-21 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective. HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge. - Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory - Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities) - Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase

Pharmaceutical Process Chemistry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527633693
Total Pages : 544 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Pharmaceutical Process Chemistry by : Takayuki Shioiri

Download or read book Pharmaceutical Process Chemistry written by Takayuki Shioiri and published by John Wiley & Sons. This book was released on 2010-12-09 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the whole area of process chemistry in the pharmaceutical industry, this monograph provides the essential knowledge on the basic chemistry needed for future development and key industrial techniques, as well as morphology, engineering and regulatory compliances. Application-oriented and well structured, the authors include recent examples of excellent industrial production of active pharmaceutical ingredients.

Pharmaceuticals and Personal Care Products: Waste Management and Treatment Technology

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Author :
Publisher : Butterworth-Heinemann
ISBN 13 : 0128165901
Total Pages : 507 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Pharmaceuticals and Personal Care Products: Waste Management and Treatment Technology by : Majeti Narasimha Vara Prasad

Download or read book Pharmaceuticals and Personal Care Products: Waste Management and Treatment Technology written by Majeti Narasimha Vara Prasad and published by Butterworth-Heinemann. This book was released on 2019-04-04 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceuticals and Personal Care Products Waste Management and Treatment Technology: Emerging Contaminants and Micro Pollutants provides the tools and techniques for identifying these contaminates and applying the most effective technology for their remediation, recovery and treatment. The consumption of pharmaceuticals and personal care products (PPCPs) has grown significantly over the last 35 years, thus increasing their potential risk to the environment. As PPCPs are very difficult to detect and remove using conventional wastewater treatment methods, this book provides solutions to a growing problem. - Includes sampling, analytical and characterization methods and technology for detecting PPCPs in the environment - Provides advanced treatment and disposal technologies for the removal of PPCPs from wastewater, surface water, landfills and septic systems - Examines the pathways of PPCPs into the environment

Patents for Chemicals, Pharmaceuticals, and Biotechnology

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Author :
Publisher : Oxford University Press, USA
ISBN 13 : 9780199684731
Total Pages : 0 pages
Book Rating : 4.6/5 (847 download)

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Book Synopsis Patents for Chemicals, Pharmaceuticals, and Biotechnology by : Philip W. Grubb

Download or read book Patents for Chemicals, Pharmaceuticals, and Biotechnology written by Philip W. Grubb and published by Oxford University Press, USA. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nature and origins of patent rights -- Historical developments -- Harmonization of patent law -- What can be patented -- Filing a patent application -- Obtaining a granted patent : patent cooperation treaty procedure -- Obtaining a granted patent : European patent office procedure -- Obtaining a granted patent : national procedures -- Maintaining a patent in force and extending the patent term -- Enforcing patent rights -- Invalidity and amendment of granted patents -- Chemical inventions -- Pharmaceutical inventions -- Biotechnological inventions -- Patenting of genes, plants, and animals -- The patent practitioner and his function -- Drafting the patent specification -- Drafting the claims -- Prosecution of the patent application to grant -- Inventorship, ownership, and compensation -- Commercial exploitation of patents -- How to catch the infringer and how not to be caught -- Patent aspects of licensing -- Patents and competition law : United Kingdom and European Union -- Patents and competition law : United States

Pharmaceuticals in the Environment

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 178262189X
Total Pages : 312 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Pharmaceuticals in the Environment by : R. E. Hester

Download or read book Pharmaceuticals in the Environment written by R. E. Hester and published by Royal Society of Chemistry. This book was released on 2016 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important reference for researchers in the pharmaceutical industry, environmentalists and policy makers wanting to better understand the impacts of pharmaceuticals on the environment.

Fine Chemicals

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Publisher : John Wiley & Sons
ISBN 13 : 0470651792
Total Pages : 258 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Fine Chemicals by : Peter Pollak

Download or read book Fine Chemicals written by Peter Pollak and published by John Wiley & Sons. This book was released on 2010-03-08 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive reference on one of the most exciting and challenging segments of the modern chemical industry. It comprises descriptions of the leading fine chemical companies, the products, markets and technologies on a global basis. It serves also as a guide for developing and succeeding in the $60 billion fine chemicals business, which is usually lumped into the chemical or pharmaceutical industry.

Clinical Pharmacology: Current Topics and Case Studies

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3709101441
Total Pages : 438 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Clinical Pharmacology: Current Topics and Case Studies by : Markus Müller

Download or read book Clinical Pharmacology: Current Topics and Case Studies written by Markus Müller and published by Springer Science & Business Media. This book was released on 2011-02-04 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today we witness an eventful time in which the powerful new forces of genomics, information technology and economics are rapidly changing the science and art of medicine. This will require more specialization than ever before. However, there is also an increasing demand for an integrated approach, which is provided by the discipline of Clinical Pharmacology (CP). CP pursues a scientific goal by studying drug action in patients and volunteers, a clinical goal by administering appropriate drug therapy and a regulatory goal by assessing the risk/benefit ratio of drug candidates in drug development and reimbursement. This introduction to current topics of CP covers traditional topics of clinical drug research and trial methodology but also provides insight in current topics like genomics, imaging technology and issues in drug reimbursement. A number of concrete case studies in clinical drug research and development help to give a better understanding of the general principles of CP.