The 25th Congress of the International Association for Breast Cancer Research

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Publisher : IOS Press
ISBN 13 : 9781586036690
Total Pages : 90 pages
Book Rating : 4.0/5 (366 download)

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Book Synopsis The 25th Congress of the International Association for Breast Cancer Research by : International association for breast cancer research. congress

Download or read book The 25th Congress of the International Association for Breast Cancer Research written by International association for breast cancer research. congress and published by IOS Press. This book was released on 2006 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: Talks about the theme 'Personalized Breast Cancer Therapy', which covers a number of areas of general interest to breast cancer researchers including sessions on pathology and molecular profiling of breast tumors, signal transduction, receptors and hormones, tumor microenvironment, cancer stem cells and clinical therapeutics.

Signaling Mechanisms Regulating T Cell Diversity and Function

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Publisher : CRC Press
ISBN 13 : 149870509X
Total Pages : 258 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Signaling Mechanisms Regulating T Cell Diversity and Function by : Jonathan Soboloff

Download or read book Signaling Mechanisms Regulating T Cell Diversity and Function written by Jonathan Soboloff and published by CRC Press. This book was released on 2017-03-27 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1456 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1993 with total page 1456 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chemical Abstracts

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Publisher :
ISBN 13 :
Total Pages : 2540 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Chemical Abstracts by :

Download or read book Chemical Abstracts written by and published by . This book was released on 2002 with total page 2540 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biological & Agricultural Index

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Publisher :
ISBN 13 :
Total Pages : 912 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Biological & Agricultural Index by :

Download or read book Biological & Agricultural Index written by and published by . This book was released on 1996 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Journal of Cell Biology

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Publisher :
ISBN 13 :
Total Pages : 608 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Journal of Cell Biology by :

Download or read book The Journal of Cell Biology written by and published by . This book was released on 1998 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: No. 2, pt. 2 of November issue each year from v. 19-47; 1963-70 and v. 55- 1972- contain the Abstracts of papers presented at the annual meeting of the American Society for Cell Biology, 3d-10th; 1963-70 and 12th- 1972- .

Molecular Biology of the Cell

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Publisher :
ISBN 13 :
Total Pages : 700 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2000 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Receptor Tyrosine Kinases: Family and Subfamilies

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Publisher : Springer
ISBN 13 : 3319118889
Total Pages : 888 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Receptor Tyrosine Kinases: Family and Subfamilies by : Deric L. Wheeler

Download or read book Receptor Tyrosine Kinases: Family and Subfamilies written by Deric L. Wheeler and published by Springer. This book was released on 2015-07-31 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book devotes a chapter to each RTK family and the multiple receptors within each family, thoroughly covering all of the RTKs. The chapters all follow the same structure, presenting this essential information in an accessible and user-friendly format. Each chapter covers one specific family of receptors and begins with a general introduction to that family and a comprehensive discussion of that receptor’s family in development and human disease. Following are in-depth analyses of each family’s receptors with discussions on the gene, protein, ligands, activation, and signaling pathways along with discussion of receptor processing and signal attenuation. Further, cross talk with other receptors systems, post-translational modification and specific unique characteristics to each RTK are discussed. Because it isolates and explains each family, this book is an essential companion volume to Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease, by the same authors, which talks about RTKs more generally and without the family-by-family detail.

Signaling by Receptor Tyrosine Kinases

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Publisher :
ISBN 13 : 9781936113330
Total Pages : 0 pages
Book Rating : 4.1/5 (133 download)

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Book Synopsis Signaling by Receptor Tyrosine Kinases by : Joseph Schlessinger

Download or read book Signaling by Receptor Tyrosine Kinases written by Joseph Schlessinger and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Receptor tyrosine kinases are cell-surface receptors that respond to numerous hormones and growth factors, including insulin, insulin-like growth factors, epidermal growth factor, and nerve growth factor. They activate highly conserved intracellular signaling pathways that regulate cell proliferation, differentiation, and metabolism, playing essential roles in developing and adult animals. This book examines the nature of these receptors and their ligands, the molecular mechanisms that they regulate within cells, and the roles of the receptors in normal physiology and control of embryogenesis. It also discusses how dysfunction of these mechanisms can contribute to cancer and other diseases.

Environmental Impacts on Reproductive Health and Fertility

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Publisher : Cambridge University Press
ISBN 13 : 9780521519526
Total Pages : 262 pages
Book Rating : 4.5/5 (195 download)

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Book Synopsis Environmental Impacts on Reproductive Health and Fertility by : Tracey J. Woodruff

Download or read book Environmental Impacts on Reproductive Health and Fertility written by Tracey J. Woodruff and published by Cambridge University Press. This book was released on 2010-01-28 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many reproductive and developmental health problems are caused by exposure to chemicals that are widely dispersed in our environment. These problems include infertility, miscarriage, poor pregnancy outcomes, abnormal fetal development, early puberty, endometriosis, and diseases and cancers of reproductive organs. The compelling nature of the collective science has resulted in recognition of a new field of environmental reproductive health. Focusing on exposures to environmental contaminants, particularly during critical periods in development and their potential effects on all aspects of future reproductive life-course, this book provides the first comprehensive source of information bringing together the arguments that are spread out among various scientific disciplines in environmental health, clinical and public health fields. It provides a review of the science in key areas of the relationship between environmental contaminants and reproductive health outcomes, and recommendations on efforts toward prevention in clinical care and public policy.

Cancer Research

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Publisher :
ISBN 13 :
Total Pages : 454 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Cancer Research by :

Download or read book Cancer Research written by and published by . This book was released on 1999 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neurogenesis and Neural Plasticity

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Publisher : Springer Science & Business Media
ISBN 13 : 364236232X
Total Pages : 447 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Neurogenesis and Neural Plasticity by : Catherine Belzung

Download or read book Neurogenesis and Neural Plasticity written by Catherine Belzung and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain. With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain.

The Growth Hormone/Insulin-Like Growth Factor Axis during Development

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Publisher : Springer Science & Business Media
ISBN 13 : 0387262741
Total Pages : 420 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis The Growth Hormone/Insulin-Like Growth Factor Axis during Development by : Isabel Varela-Nieto

Download or read book The Growth Hormone/Insulin-Like Growth Factor Axis during Development written by Isabel Varela-Nieto and published by Springer Science & Business Media. This book was released on 2005-12-17 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Insulin-like growth factor (IGF)-I is a widely expressed growth factor with diverse effects on many tissues throughout development and in adult life. The purpose of this work is to provide detailed and updated information on the role of the growth hormone (GH)-IGF axis in fetal and postnatal development, as well as its physiological functions and implications in pathology.

MCQs in Biochemistry

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Publisher : New Age International
ISBN 13 : 8122423574
Total Pages : 16 pages
Book Rating : 4.1/5 (224 download)

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Book Synopsis MCQs in Biochemistry by : G. Vidya Sagar

Download or read book MCQs in Biochemistry written by G. Vidya Sagar and published by New Age International. This book was released on 2008 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical and Paramedical graduates aspiring for higher education planning to take PG ought to appear in entrance examinations. These entrance examinations are usually patterned in objective type. Biochemistry forms an integral part of curriculum of medical and paramedical courses. It is an important subject and deals with various Chemical, Biochemical, and Physiological reactions and processes that take place inside a living system. Quite a large number of MCQs appear in PG medical and paramedica.

Recent Advances in Glucocorticoid Receptor Action

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540432296
Total Pages : 410 pages
Book Rating : 4.4/5 (322 download)

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Book Synopsis Recent Advances in Glucocorticoid Receptor Action by : A. Cato

Download or read book Recent Advances in Glucocorticoid Receptor Action written by A. Cato and published by Springer Science & Business Media. This book was released on 2002-09-12 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The long-term use of glucocorticoids is associated with several deleterious effects. Attempts to separate the beneficial from the adverse effects of these compounds have met with varying degrees of difficulty. The discovery of distinct modes of action of the glucocorticoid receptor, the protein that mediates glucocorticoid action has opened up many possibilities for improving glucocorticoid therapy. This book provides an in-depth overview of the molecular actions of the glucocorticoid receptor and discusses the chances of an imminent identification of selective glucocorticoid agonists. Such componds should fulfill all the criteria of a glucocorticoid but should lack the sideeffects so far linked with classical glucocorticoids.

Advances in Immunohistochemistry

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Publisher :
ISBN 13 :
Total Pages : 386 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Advances in Immunohistochemistry by : Ronald A. DeLellis

Download or read book Advances in Immunohistochemistry written by Ronald A. DeLellis and published by . This book was released on 1984 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis

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Publisher : Springer Nature
ISBN 13 : 3030291685
Total Pages : 564 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis by : Padma V. Devarajan

Download or read book Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis written by Padma V. Devarajan and published by Springer Nature. This book was released on 2019-11-09 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book elaborates on drug delivery targeting via intracellular delivery, specifically through the Receptor Mediated Endocytosis (RME) approach, due to the involvement of cellular receptors in various grave diseases. Targeted delivery relies on two basic approaches, passive and active targeting. While passive targeting approaches have shown great promise, the improved selectivity achieved with active targeting approaches has resulted in significantly higher efficacy. Interestingly there are numerous strategies for active targeting, many of which are already highlighted in , Targeted Drug Delivery: Concepts and Applications. Nevertheless an exciting and practical strategy for active targeting, which could enable high intracellular delivery, is through exploitation of RME. Cells in the body express receptors to enable various physiological and biochemical processes. As a result, many of these receptors are overexpressed in pathological conditions, or newer receptors expressed due to defective cellular functioning. RME is based on exploitation of such receptors to achieve intracellular delivery. While targeted delivery can have manifold applications, in this book we focus on two major and challenging therapeutic areas; i) Cancer and ii) Infectious Diseases. Targeted Intracellular Drug Delivery by Receptor Medicated Endocytosis discusses the major receptors that are useful for targeted delivery for these afflictions. A major section of this book is dedicated to details regarding their occurrence and location, the recognition domain of the receptor, structure activity relationship of substrate /ligand for selective binding, ligands explored, antagonists for ligand binding and relevance of these aspects for therapy of cancer and infectious diseases. These facets are elucidated with the help of specific examples from academic research and also emphasize commercial products, wherever relevant. In vitro cellular models relied on for assessing receptor mediated cellular targeting and in vivo models depicting clinical efficacy are focused on in a separate section. Finally, we briefly discuss the regulatory and toxicity issues that may be associated specifically with the RME approach of intracellular drug delivery.