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Author : Kyungmin Benjamin Hahm
Publisher :
ISBN 13 :
Total Pages : 382 pages
Book Rating : 4.:/5 ( download)
Download or read book Characterization of Transcription Factor LyF-1/Ikaros written by Kyungmin Benjamin Hahm and published by . This book was released on 1997 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Harinder Singh
Publisher : Springer Science & Business Media
ISBN 13 : 3540263632
Total Pages : 261 pages
Book Rating : 4.5/5 (42 download)
Download or read book Molecular Analysis of B Lymphocyte Development and Activation written by Harinder Singh and published by Springer Science & Business Media. This book was released on 2006-03-30 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell development and terminal plasma cell differentiation. In addition new insights became available for the processes of B cell activation, class switch recombination and somatic hypermutation. Many of the new findings and their implications for a molecular understanding of B cell biology in particular and cell differentiation in general are covered in this volume.
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ISBN 13 :
Total Pages : 830 pages
Book Rating : 4.F/5 ( download)
Download or read book Dissertation Abstracts International written by and published by . This book was released on 1997 with total page 830 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : James John Achilles Contos
Publisher :
ISBN 13 :
Total Pages : 534 pages
Book Rating : 4.:/5 (318 download)
Download or read book Genomic and Functional Characterization of Lysophospholipid Receptor Genes written by James John Achilles Contos and published by . This book was released on 1999 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rupa Sridharan
Publisher :
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.:/5 ( download)
Download or read book Analysis of the Ikaros Family of Proteins in Thymocyte Development written by Rupa Sridharan and published by . This book was released on 2006 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Katya Ravid
Publisher : John Wiley & Sons
ISBN 13 : 0471461067
Total Pages : 640 pages
Book Rating : 4.4/5 (714 download)
Download or read book Transcription Factors written by Katya Ravid and published by John Wiley & Sons. This book was released on 2003-11-04 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transcription Factors Normal and Malignant Development of Blood Cells Katya Ravid and Jonathan Licht The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies). Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification and characterization of chromosomal rearrangement in human blood leukemias. This complete digest of current transcription factor data offers comprehensive coverage of the myriad of transcription factors in blood cell development, composed by established experts in the field. In addition to updating the reader on the connection between chromosomal translocations involving transcription factors and cellular transformation leading to leukemia, Transcription Factors also reviews such subjects as: * Transcription factors and the megakaryocytic, myeloid, and erythroid lineages * Leukemias due to chromosomal translocations involving gene encoding transcription factors * Oncogenesis and hematopoiesis * In vivo studies of transcription factors implicated in hematopoiesis * And much more Appealing to both the researcher and the clinician in the field of hematology, Transcription Factors is a timely presentation of cell lineage development and sheds light on the processes involved in the development of specific leukemias. Providing insight into the study of transcription factors, readers will gain an understanding of mechanisms that lead to normal lineage commitment and terminal differentiation.
Author : John G. Monroe
Publisher : Springer Science & Business Media
ISBN 13 : 147572778X
Total Pages : 582 pages
Book Rating : 4.4/5 (757 download)
Download or read book Molecular Biology of B-Cell and T-Cell Development written by John G. Monroe and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the tremendous diversity of the cells of the hematopoietic system, they are all derived from common precursor cells that are generated in the fetus and persist into adult life. In this regard, Band T lymphocytes, which comprise the two arms of the antigen-specific and inducible immune system, though functionally very different, are descendants of the same stem cell precursor. In the past several years, we have witnessed an explosion of information regarding the process by which differentiation of B-and T-cells from stem cells occurs. This information, like the answers to most important biological questions, has come from multiple and diverse directions. Because all hematopoietic cells arise from common precursors, complex regulatory processes must be involved in determining commitment to various lineages. Understanding commitment to the B- or T-cell lineage remains incomplete; however, identification of transcription factors necessary for progression along specific B-and T-cell pathways suggests that we are on the verge of understanding the molecules involved in the initial fate-determining steps. Studies of this type previously could be accomplished only in nonmammalian systems that are more amenable to genetic approaches. However, new technologies allow increasingly elegant and informative studies in mammalian systems, particularly for cells of the hematopoietic system.
Author : Roger Louis Ferrini
Publisher :
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.:/5 ( download)
Download or read book Ikaros written by Roger Louis Ferrini and published by . This book was released on 2005 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Tasuku Honjo
Publisher : Elsevier
ISBN 13 : 0123984904
Total Pages : 587 pages
Book Rating : 4.1/5 (239 download)
Download or read book Molecular Biology of B Cells written by Tasuku Honjo and published by Elsevier. This book was released on 2014-10-09 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics. - Covers signaling mechanisms regulating B cell differentiation - Provides information on the development of therapeutics using monoclonal antibodies and clinical application of Ab - Contains studies on B cell tumors from various stages of B lymphocytes - Offers an integrated view of all aspects of B cells to produce a normal immune response
Author :
Publisher :
ISBN 13 :
Total Pages : 872 pages
Book Rating : 4.3/5 (91 download)
Download or read book American Doctoral Dissertations written by and published by . This book was released on 1996 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 476 pages
Book Rating : 4.3/5 (91 download)
Download or read book Genetics Abstracts written by and published by . This book was released on 1997 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
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ISBN 13 :
Total Pages : 1860 pages
Book Rating : 4.:/5 (319 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1997 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David P. Bazett-Jones
Publisher : Springer
ISBN 13 : 3319388827
Total Pages : 501 pages
Book Rating : 4.3/5 (193 download)
Download or read book The Functional Nucleus written by David P. Bazett-Jones and published by Springer. This book was released on 2016-10-17 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.
Author : L. Du Pasquier
Publisher : Springer Science & Business Media
ISBN 13 : 3642596746
Total Pages : 324 pages
Book Rating : 4.6/5 (425 download)
Download or read book Origin and Evolution of the Vertebrate Immune System written by L. Du Pasquier and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop ment of the principal concepts that created the foundation of what now is the broad field of immunology. With each major experimental and conceptual breakthrough, the classical, albeit essential, question has been asked "are the immune systems of phylogenetically primitive vertebrates and invertebrates similar to that of mammals?" Somewhat surprisingly for the jawed verte brates, the general answer has been a qualified form of "yes", whereas for agnathans and invertebrate phyla it has been "no" so far. The apparent abruptness in the appearance of the immune system of vertebrates is linked to the introduction of the somatic generation of the diversity of its antigen specific receptors. Therefore the questions regarding the origin and evolution of the specific immune system revolve around this phenomenon. With respect to the origin of the system (aside from the or igin of the rearranging machinery itself, the study of which is still in its infancy) one can ask questions about the cellular and mo lecular contexts in which the mechanism was introduced.
Author :
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ISBN 13 :
Total Pages : 962 pages
Book Rating : 4.X/5 (6 download)
Download or read book Nucleic Acids Abstracts written by and published by . This book was released on 1995-11 with total page 962 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Patricia Ann Ernst
Publisher :
ISBN 13 :
Total Pages : 244 pages
Book Rating : 4.:/5 ( download)
Download or read book Regulation of the Terminal Transferase Gene in Developing Lymphocytes written by Patricia Ann Ernst and published by . This book was released on 1996 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
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ISBN 13 :
Total Pages : 1218 pages
Book Rating : 4.:/5 (31 download)
Download or read book The Journal of Immunology written by and published by . This book was released on 2004 with total page 1218 pages. Available in PDF, EPUB and Kindle. Book excerpt:
