Challenges of Biological Aging

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Publisher : Springer Publishing Company
ISBN 13 : 0826100821
Total Pages : 218 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Challenges of Biological Aging by : Edward J. Masoro

Download or read book Challenges of Biological Aging written by Edward J. Masoro and published by Springer Publishing Company. This book was released on 2000-09-05 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides the non-biologist an overview of what is known about the physiological bases of aging. The author examines the many basic theories and emerging hypotheses underlying the molecular, cellular, and systemic processes involved in senescence. He addresses the normal physiological changes that characterize the aging phenotype, and also considers the role of many age-associated diseases in growing older. Masoro synthesizes a much-needed "unified theory" of biological aging to which explains how and why the body grows into the condition we call "old." This text is intended for gerontology students in training, as well as for human physiologists interested in gerontology.

Problems of Ageing

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Publisher :
ISBN 13 :
Total Pages : 1100 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Problems of Ageing by : Edmund Vincent Cowdry

Download or read book Problems of Ageing written by Edmund Vincent Cowdry and published by . This book was released on 1952 with total page 1100 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Epigenetics of Aging

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1441906398
Total Pages : 462 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Epigenetics of Aging by : Trygve O. Tollefsbol

Download or read book Epigenetics of Aging written by Trygve O. Tollefsbol and published by Springer Science & Business Media. This book was released on 2009-11-11 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

The Challenge

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Publisher :
ISBN 13 :
Total Pages : 11 pages
Book Rating : 4.:/5 (387 download)

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Book Synopsis The Challenge by : Charles H. Barrows

Download or read book The Challenge written by Charles H. Barrows and published by . This book was released on 1971 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Problems of Ageing

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Publisher :
ISBN 13 :
Total Pages : 808 pages
Book Rating : 4.:/5 (43 download)

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Book Synopsis Problems of Ageing by : Edmund Vincent Cowdry

Download or read book Problems of Ageing written by Edmund Vincent Cowdry and published by . This book was released on 1979 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt:

New Directions in the Sociology of Aging

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Publisher : National Academies Press
ISBN 13 : 9780309292979
Total Pages : 301 pages
Book Rating : 4.2/5 (929 download)

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Book Synopsis New Directions in the Sociology of Aging by : Panel on New Directions in Social Demography, Social Epidemiology, and the Sociology of Aging

Download or read book New Directions in the Sociology of Aging written by Panel on New Directions in Social Demography, Social Epidemiology, and the Sociology of Aging and published by National Academies Press. This book was released on 2014-01-09 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aging of the population of the United States is occurring at a time of major economic and social changes. These economic changes include consideration of increases in the age of eligibility for Social Security and Medicare and possible changes in benefit levels. Furthermore, changes in the social context in which older individuals and families function may well affect the nature of key social relationships and institutions that define the environment for older persons. Sociology offers a knowledge base, a number of useful analytic approaches and tools, and unique theoretical perspectives that can facilitate understanding of these demographic, economic, and social changes and, to the extent possible, their causes, consequences and implications. The Future of the Sociology of Aging: An Agenda for Action evaluates the recent contributions of social demography, social epidemiology and sociology to the study of aging and identifies promising new research directions in these sub-fields. Included in this study are nine papers prepared by experts in sociology, demography, social genomics, public health, and other fields, that highlight the broad array of tools and perspectives that can provide the basis for further advancing the understanding of aging processes in ways that can inform policy. This report discusses the role of sociology in what is a wide-ranging and diverse field of study; a proposed three-dimensional conceptual model for studying social processes in aging over the life cycle; a review of existing databases, data needs and opportunities, primarily in the area of measurement of interhousehold and intergenerational transmission of resources, biomarkers and biosocial interactions; and a summary of roadblocks and bridges to transdisciplinary research that will affect the future directions of the field of sociology of aging.

The Biology of Ageing

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Author :
Publisher : CRC Press
ISBN 13 : 1000605191
Total Pages : 355 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis The Biology of Ageing by : Gurcharan Rai

Download or read book The Biology of Ageing written by Gurcharan Rai and published by CRC Press. This book was released on 2022-02-16 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the problems geriatricians are confronted with in everyday clinical practice is differentiating disease from the process of old age. The challenges of ageing require a better understanding of the essential biology of ageing in order to separate ageing from disease, and indeed ageing made worse by disease. Although the topic is large and diverse, this practical and easy-to-read reference book contains vital information on the biology of ageing. It provides a concise understanding of the changes that occur and focuses on the clinical implications of ageing. MCQs are featured throughout for revision and examination practice. The Biology of Ageing provides the reader with: . a learning guide on the biology of ageing through an overview of the changes that occur at both cellular and system levels . knowledge of how biological changes of ageing impact on physiology and the clinical relevance in medical practice . a practical consideration of these changes in disease presentations and how these changes may impact on disease management. This full-colour guide featuring slides, MRIs, figures and photographs is ideal for doctors training in geriatric medicine, practising geriatricians and those with an interest in management of older people.

The Biology of Senescence

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Author :
Publisher : CreateSpace
ISBN 13 : 9781456392420
Total Pages : 274 pages
Book Rating : 4.3/5 (924 download)

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Book Synopsis The Biology of Senescence by : Alex Comfort

Download or read book The Biology of Senescence written by Alex Comfort and published by CreateSpace. This book was released on 2010-11-25 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biology of Senescence

Research at the Intersection of the Physical and Life Sciences

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Publisher : National Academies Press
ISBN 13 : 0309147514
Total Pages : 122 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Research at the Intersection of the Physical and Life Sciences by : National Research Council

Download or read book Research at the Intersection of the Physical and Life Sciences written by National Research Council and published by National Academies Press. This book was released on 2010-03-25 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally, the natural sciences have been divided into two branches: the biological sciences and the physical sciences. Today, an increasing number of scientists are addressing problems lying at the intersection of the two. These problems are most often biological in nature, but examining them through the lens of the physical sciences can yield exciting results and opportunities. For example, one area producing effective cross-discipline research opportunities centers on the dynamics of systems. Equilibrium, multistability, and stochastic behavior-concepts familiar to physicists and chemists-are now being used to tackle issues associated with living systems such as adaptation, feedback, and emergent behavior. Research at the Intersection of the Physical and Life Sciences discusses how some of the most important scientific and societal challenges can be addressed, at least in part, by collaborative research that lies at the intersection of traditional disciplines, including biology, chemistry, and physics. This book describes how some of the mysteries of the biological world are being addressed using tools and techniques developed in the physical sciences, and identifies five areas of potentially transformative research. Work in these areas would have significant impact in both research and society at large by expanding our understanding of the physical world and by revealing new opportunities for advancing public health, technology, and stewardship of the environment. This book recommends several ways to accelerate such cross-discipline research. Many of these recommendations are directed toward those administering the faculties and resources of our great research institutions-and the stewards of our research funders, making this book an excellent resource for academic and research institutions, scientists, universities, and federal and private funding agencies.

Health, Illness, and Optimal Aging

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Publisher : SAGE Publications
ISBN 13 : 1452266980
Total Pages : 441 pages
Book Rating : 4.4/5 (522 download)

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Book Synopsis Health, Illness, and Optimal Aging by : Carolyn M. Aldwin

Download or read book Health, Illness, and Optimal Aging written by Carolyn M. Aldwin and published by SAGE Publications. This book was released on 2003-07-17 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: FROM THE FOREWORD by James Birren: "Gaining understanding of aging is one of the most complex issues facing twenty-first century science. This book addresses the complexity of the factors that interact and influence the course of our longer life expectancy....How we humans grow old is a product of our genetic background as members of a species and our families. But the genome expresses itself in physical and social environments that modulate the appearance of heredity traits. In a sense aging is an ecological problem in which the dynamics are often difficult to explain....This book brings information from the sciences together in a way that is rarely done.....It provides an integration of knowledge about the dynamics of aging and can promote wisdom about how we can modify the life course to our advantage." In Health, Illness, and Optimal Aging: Biological and Psychosocial Perspectives, Carolyn M. Aldwin and Diane F. Gilmer undertake the challenging task of assembling an objective and holistic picture of human aging. The authors provide comprehensive, multidisciplinary coverage of the physical aspects of aging, including age-related changes and disease-related processes, the demography of the aging population, theories of aging, and the promotion of optimal aging. In addition, the book covers the psychosocial aspects of aging, including mental health, stress and coping, spirituality, and care giving in later years. Features of this book: Integrated. Discusses both the biological aspects and psychosocial factors of aging, thus providing integrated coverage of information from the fields of biology, psychology, and the social sciences. Discusses both the biological aspects and psychosocial factors of aging, thus providing integrated coverage of information from the fields of biology, psychology, and the social sciences. Comprehensive. Covers every part of the aging process including the physical effect on the different systems of the human body, quality of life, social support, and health promotion programs. Covers every part of the aging process including the physical effect on the different systems of the human body, quality of life, social support, and health promotion programs. Pedagogical. Examples in each chapter enhance students′ understanding of real-life situations, and methodological issues help students become more critical consumers of research and data.Examples in each chapter enhance students′ understanding of real-life situations, and methodological issues help students become more critical consumers of research and data. Discusses both the biological aspects and psychosocial factors of aging, thus providing integrated coverage of information from the fields of biology, psychology, and the social sciences. Covers every part of the aging process including the physical effect on the different systems of the human body, quality of life, social support, and health promotion programs. Examples in each chapter enhance students′ understanding of real-life situations, and methodological issues help students become more critical consumers of research and data. Discusses both the biological aspects and psychosocial factors of aging, thus providing integrated coverage of information from the fields of biology, psychology, and the social sciences. Covers every part of the aging process including the physical effect on the different systems of the human body, quality of life, social support, and health promotion programs. Examples in each chapter enhance students′ understanding of real-life situations, and methodological issues help students become more critical consumers of research and data. Discusses both the biological aspects and psychosocial factors of aging, thus providing integrated coverage of information from the fields of biology, psychology, and the social sciences. Covers every part of the aging process including the physical effect on the different systems of the human body, quality of life, social support, and health promotion programs. Examples in each chapter enhance students′ understanding of real-life situations, and methodological issues help students become more critical consumers of research and data. Health, Illness and Optimal Aging is recommended for researchers seeking an overview of health psychology and aging, as well as undergraduate and graduate students taking classes in the social, behavioral, and health sciences. This text is also valuable for practitioners working with the elderly in fields such as nursing, social work, occupational and physical therapy, day-care and nursing home administration, psychology, and rehabilitation.

Biochemistry and Cell Biology of Ageing: Part II Clinical Science

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Author :
Publisher : Springer
ISBN 13 : 9811336814
Total Pages : 499 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Biochemistry and Cell Biology of Ageing: Part II Clinical Science by : J. Robin Harris

Download or read book Biochemistry and Cell Biology of Ageing: Part II Clinical Science written by J. Robin Harris and published by Springer. This book was released on 2019-03-19 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the subcellular Biochemistry series will attempt to bridge the gap between the subcellular events that are related to aging as they were described in the first volume of this set of two books and the reality of aging as this is seen in clinical practice. All chapters will start from the biochemistry or cell biology, where the data is available and work up towards the understanding that we have of aging in the various areas that are related to the subject. Key focus points for this volume are nutrition, external factors and genetics on aging. There will also be chapters that will focus on various organs or tissues in which aging has been well studied, like the eyes, the muscles, the immune system and the bones. The aim of the book project and the book project that is published in concert with this volume is to bring the subcellular and clinical areas into closer contact.

Problems of ageing

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Publisher :
ISBN 13 :
Total Pages : 758 pages
Book Rating : 4.:/5 (17 download)

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Book Synopsis Problems of ageing by : E. V. Cowdry

Download or read book Problems of ageing written by E. V. Cowdry and published by . This book was released on 1940 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Social and Biological Challenge of Our Aging Population

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Publisher :
ISBN 13 :
Total Pages : 206 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Social and Biological Challenge of Our Aging Population by :

Download or read book The Social and Biological Challenge of Our Aging Population written by and published by . This book was released on 1950 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Epigenetics of Aging and Longevity

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Publisher : Academic Press
ISBN 13 : 012811083X
Total Pages : 546 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Epigenetics of Aging and Longevity by : Alexey Moskalev

Download or read book Epigenetics of Aging and Longevity written by Alexey Moskalev and published by Academic Press. This book was released on 2017-11-17 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses—including cancer and cardiovascular, metabolic, and neurodegenerative diseases—are explored in detail. This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease. Offers a comprehensive overview of the epigenetic nature of aging, as well as the impact of epigenetic factors on longevity and regulating age-related disease Provides readers with clinical and epidemiological evidence for the role of epigenetic mechanisms in mediating the link between early-life experiences, life-course health and aging trajectory Applies current knowledge of epigenetic regulatory pathways towards developing therapeutic interventions for age-related diseases and extending the human lifespan

Challenges in Aging

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Publisher :
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Challenges in Aging by : Manfred Bergener

Download or read book Challenges in Aging written by Manfred Bergener and published by . This book was released on 1990 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for cell and molecular biologists interested in the ageing process, gerontologists, psychologists and psychiatrists, this book discusses such topics as age-associated memory-impairment, the position of the old in tribal societies, and other associated conditions.

Human Aging

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Publisher : Academic Press
ISBN 13 : 0128227370
Total Pages : 382 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Human Aging by : Calogero Caruso

Download or read book Human Aging written by Calogero Caruso and published by Academic Press. This book was released on 2021-05-11 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Aging: From Cellular Mechanisms to Therapeutic Strategies offers an exhaustive picture of all the biological aspects of human aging by describing the key mechanisms associated with human aging and covering events that could disrupt the normal course of aging. Each chapter includes a summary of the salient points covered, along with futures prospects. The book provides readers with the information they need to gain or deepen the skills needed to evaluate the mechanisms of aging and age-related diseases and to monitor the effectiveness of therapies aimed at slowing aging. The book encourages PhD and Postdoc students, researchers, health professionals and others interested in the biology of aging to explore the fascinating and challenging questions about why and how we age as well as what can and cannot be done about it. Concentrates on different processes, e.g., oxidative stress, cellular senescence and Inflammaging Offers the ability to access cross-sectional knowledge more easily Written by expert researchers in biogerontology who are actively involved in various fields within aging research

Proceedings

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Publisher :
ISBN 13 :
Total Pages : 183 pages
Book Rating : 4.:/5 (556 download)

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Book Synopsis Proceedings by :

Download or read book Proceedings written by and published by . This book was released on 1951 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: